The basophil activation test in wasp venom allergy: Sensitivity, specificity and monitoring specific immunotherapy

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 59, Issue 10, 2004, Pages 1102-1109

  Erdmann, Stephan M ^a,b   Sachs, B ^a   Kwiecien, R ^b   Moll Slodowy, S ^a   Sauer, I ^a   Merk, H F ^a  

^a Dept of Dermatol and Allergology ^*  (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Basophil; Basophil activation; CD63 expression; Flow cytometry; Hymenoptera allergy

Indexed keywords

BEE VENOM; CD63 ANTIGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; MONOCLONAL ANTIBODY; WASP VENOM;

ADULT; ALLERGY; ANTIGEN EXPRESSION; ARTICLE; BASOPHIL; BASOPHIL ACTIVATION TEST; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; HUMAN; HYMENOPTERA; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOTHERAPY; IN VITRO STUDY; INSECT STING; LABORATORY TEST; PATIENT MONITORING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SENSITIZATION; SKIN TEST;

ADOLESCENT; ADULT; ANTIGENS, CD; BASOPHILS; BEE VENOMS; DESENSITIZATION, IMMUNOLOGIC; FLOW CYTOMETRY; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; MIDDLE AGED; PLATELET MEMBRANE GLYCOPROTEINS; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SKIN TESTS; WASP VENOMS;

EID: 4644294332     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2004.00624.x     Document Type: Article

References (30)

1. MÜLLER U, MOSBECH H. Position paper: Immunotherapy with Hymenoptera venoms. Allergy 1993;48(Suppl. 14):37-46.
2. RUEFF F, PRZYBILLA B, MÜLLER U, MOSBECH H. Position paper. The sting challenge test in Hymenoptera venom allergy. Allergy 1996;51:216-225.
3. KNOL EF, MUL FP, JANSEN H, CALAFAT J, ROOS D. Monitoring human basophil activation via CD63 monoclonal antibody 435. J Allergy Clin Immunol 1991;88:328-338.
4. NIEUWENHUIS HK, VAN OOSTERHOUT JJG, ROZEMULLER E, VAN IWAARDEN F, SIXMAA JJ. Studies with a monoclonal antibody against activated platelets: evidence that a secreted 53,000 molecular weight lysosome-like granule protein is exposed on the surface of activated platelets in the circulation. Blood 1987;266:3239-3245.
5. METZELAAR M, WIJNGAARD PLJ, PETERS PJ, SIXMA JJ, NIEUWENHUIS HK, CLEVERS HC. CD63 antigen: a novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. J Biol Chem 1991;266:3239-3245.
6. SAINTE-LAUDY J, VALLON C, GUERIN JC. Diagnosis of latex allergy: comparison of histamine release and flow cytometric analysis of basophil activation. Inflamm Res 1996;45:35-36.
7. EBO DG, LECHKAR B, SCHUERWEGH AJ, BRIDTS CH, DE CLERCK LS, STEVENS WJ. Validation of a two-color flow cytometric assay detecting in vitro basophil activation for the diagnosis of IgE-mediated natural rubber latex allergy. Allergy 2002;57:706-712.
8. ERDMANN SM, HEUSSEN N, MOLLSLODOWY S, MERK HF, SACHS B. CD63 expression on basophils as a tool for the diagnosis of pollen-associated food allergy: sensitivity and specificity. Clin Exp Allergy 2003;33:607-614.
9. PARIS-KOHLER A, DEMOLY P, PERSI L, LEBEL B, BOUSQUET J, ARNOUX B. In vitro diagnosis of cypress pollen allergy by using cytofluorimetric analysis of basophils. J Allergy Clin Immunol 2000;105:339-345.
10. SAPORTA M, KAMEI S, PERSI L, BOUSQUET L, ARNOUX B. Basophil activation during pollen season in patients monosensitized to grass pollens. Allergy 2001;56:442-445.
11. SAINTE-LAUDY J, SABBAH A, DROUET M, LAURET MG, LOIRY M. Diagnosis of venom allergy by flow cytometry. Correlation with clinical history, skin tests, specific IgE, histamine and leukotriene C4 release. Clin Exp Allergy 2000;30:1166-1171.
12. SANZ ML, GAMBOA PM, ANTÉPARA I, USUAF C, VILA L, GARCIA-AVILÉS C et al. Flow cytometric basophil activation test by detection of CD63 expression in patients with immediate-type reactions to betalactam antibiotics. Clin Exp Allergy 2002;32:277-287.
13. MÜLLER HL. Diagnosis and treatment of insect sensitivity. J Asthma Res 1966;3:331-333.
14. The European Academy of Allergology and Clinical Immunology. Allergen standardization and skin tests. Allergy 1993;48(Suppl. 14):48-82.
15. DE WECK A, SANZ ML. Flow cytometric cellular allergen stimulation test. Technical and clinical evaluation of a new diagnostic test in allergy and pseudoallergy. ACI International 2002;14:2-13.
16. ZWEIG MH, CAMPBELL G. Receiver-operating characteristics (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 1993;39:561-577.
17. GOLDMAN L. Quantitative aspects of clinical reasoning. In: BRAUNWALD E, editor. Principles of Internal Medicine. New York: McGraw-Hill, 1987:5-11.
18. FRANKEN HH, DUBOIS AE, MINKEMA HJ, VAN DER HEIDE S, DE MONCHY JG. Lack of reproducibility of a single negative sting challenge response in the assessment of anaphylactic risk in patients with suspected yellow jacket hypersensitivity. J Allergy Clin Immunol 1994;93:431-436.
19. MACGLASHAN DW. Releasability of human basophils: Cellular sensitivity and maximal histamine release are independent variables. J Allergy Clin Immunol 1993;91:605-615.
20. KLEINE-TEBBE J. Basophil histamine release by freshly prepared food extracts. Allergy Proc 1993;14:55-58.
21. CROCKARD AD, ENNIS M. Laboratory-based allergy diagnosis: should we go with the flow? Clin Exp Allergy 2001;31:975-977.
22. SIRAGANIAN RP, HOOK WA. Mechanism of histamine release by formyl methionine-containing peptides. J Immunol 1977;119:2078-2083.
23. NGUYEN K-L, GILLIS S, MACGLASHAN DW. A comparative study of releasing and nonreleasing human basophils: nonreleasing basophils lack an early component of the signal transduction pathway that follws IgE cross-linking. J Allergy Clin Immunol 1990;85:1020-1029.
24. KEPLEY CL, YOUSSEF L, ANDREWS RP, WILSON BS, OLIVER JM. Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion. J Immunol 2000;165:5913-5920.
25. MACGLASHAN DW, PETERS SP, WARNER J, LICHTENSTEIN LM. Characteristics of human basophil sulfidopeptide leukotriene release: releasability defined as the ability of the basophil to respond to dimeric cross-links. J Immunol 1986;136:2231-2239.
26. AKDIS CA, BLASER K. Mechanisms of allergen-specific immunotherapy. Allergy 2000;55:522-530.
27. AKDIS CA, BLASER K. IL-10 induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy. FASEB J 1999;13:603-609.
28. GRAFT DF, GOLDEN DBK, REISMAN RE, VALENTINE MD, YUNGINGER JW. Position statement. The discontinuation of Hymenoptera venom immunotherapy. J Allergy Clin Immunol 1998;101:573-575.
29. SCHROEDER JT, KAGEY-SOBOTKA A, LICHTENSTEIN LM. The role of the basophil in allergic inflammation. Allergy 1995;50:463-472.
30. MÜLLER UR. New developments in the diagnosis and treatment of hymenoptera venom allergy. Int Arch Allergy Immunol 2001;124:447-453.