Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Straud, Sarah ^a   Zubovych, Iryna ^a   de Brabander, Jef K ^a   Roth, Michael G ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FERROPORTIN; IRON; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE INHIBITOR; REACTIVE OXYGEN METABOLITE; ANTINEMATODAL AGENT; BAFILOMYCIN A; CATION TRANSPORT PROTEIN; FUSED HETEROCYCLIC RINGS; MACROLIDE; METAL TRANSPORTING PROTEIN 1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG TARGETING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; IRON METABOLISM; IRON TRANSPORT; MELANOMA CELL; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; NEOPLASM; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEMATODAL AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, WESTERN; CATION TRANSPORT PROTEINS; CELL LINE; CELL LINE, TUMOR; CHOLESTEROL; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; IRON; MACROLIDES; NEOPLASMS; REACTIVE OXYGEN SPECIES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 77955363186     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011629     Document Type: Article

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