-
1
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899-911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
2
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, Gonzalez-Garcia M, Postema CE et al. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74: 597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
-
3
-
-
0027166048
-
Bcl-2 heterodimerizes in.vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in.vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-19.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
4
-
-
0032528118
-
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
-
Gross A, Jockel J, Wei MC, Korsmeyer SJ. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J 1998; 17: 3878-85.
-
(1998)
EMBO J
, vol.17
, pp. 3878-3885
-
-
Gross, A.1
Jockel, J.2
Wei, M.C.3
Korsmeyer, S.J.4
-
5
-
-
20544437817
-
Unknotting the roles of Bcl-2 and Bcl-xL in cell death
-
Kim R. Unknotting the roles of Bcl-2 and Bcl-xL in cell death. Biochem Biophys Res Commun 2005; 333: 336-43.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 336-343
-
-
Kim, R.1
-
6
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397: 441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
7
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li LY, Luo X, Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 2001; 412: 95-9.
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
8
-
-
0035930523
-
Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: Cooperation with exonuclease and DNase I
-
Widlak P, Li LY, Wang X, Garrard WT. Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I. J Biol Chem 2001; 276: 48 404-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 48404-48409
-
-
Widlak, P.1
Li, L.Y.2
Wang, X.3
Garrard, W.T.4
-
9
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K et al. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 1997; 275: 1129-32.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
10
-
-
0021821903
-
Involvement of the bcl-2 gene in human follicular lymphoma
-
Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985; 228: 1440-3.
-
(1985)
Science
, vol.228
, pp. 1440-1443
-
-
Tsujimoto, Y.1
Cossman, J.2
Jaffe, E.3
Croce, C.M.4
-
11
-
-
0242721548
-
Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists
-
Wang S, Yang D, Lippman ME. Targeting Bcl-2 and Bcl-XL with nonpeptidic small-molecule antagonists. Semin Oncol 2003; 30: 133-42.
-
(2003)
Semin Oncol
, vol.30
, pp. 133-142
-
-
Wang, S.1
Yang, D.2
Lippman, M.E.3
-
12
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang JL, Liu D, Zhang ZJ et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc Natl Acad Sci USA 2000; 97: 7124-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7124-7129
-
-
Wang, J.L.1
Liu, D.2
Zhang, Z.J.3
-
13
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005; 435: 677-81.
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
-
14
-
-
0141569444
-
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/ leukemia-2 proteins
-
Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins. J Med Chem 2003; 46: 4259-64.
-
(2003)
J Med Chem
, vol.46
, pp. 4259-4264
-
-
Kitada, S.1
Leone, M.2
Sareth, S.3
Zhai, D.4
Reed, J.C.5
Pellecchia, M.6
-
15
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed JC. Double identity for proteins of the Bcl-2 family. Nature 1997; 387: 773-6.
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
16
-
-
0038165498
-
Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion
-
Kawatani M, Imoto M. Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion. J Biol Chem 2003;278: 19 732-42.
-
(2003)
J Biol Chem
, vol.278
, pp. 19732-19742
-
-
Kawatani, M.1
Imoto, M.2
-
17
-
-
39049087313
-
Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin
-
Futamura Y, Sawa R, Umezawa Y et al. Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin. J Am Chem Soc 2008; 130: 1822-3.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 1822-1823
-
-
Futamura, Y.1
Sawa, R.2
Umezawa, Y.3
-
18
-
-
0024998009
-
Isolation and structure determination of inostamycin, a novel inhibitor of phosphatidylinositol turnover
-
Imoto M, Umezawa K, Takahashi Y et al. Isolation and structure determination of inostamycin, a novel inhibitor of phosphatidylinositol turnover. J Nat Prod 1990; 53: 825-9.
-
(1990)
J Nat Prod
, vol.53
, pp. 825-829
-
-
Imoto, M.1
Umezawa, K.2
Takahashi, Y.3
-
19
-
-
0036384309
-
Induction of EGF-dependent apoptosis by vacuolar-type H(+)-ATPase inhibitors in A431 cells overexpressing the EGF receptor
-
Yoshimoto Y, Imoto M. Induction of EGF-dependent apoptosis by vacuolar-type H(+)-ATPase inhibitors in A431 cells overexpressing the EGF receptor. Exp Cell Res 2002; 279: 118-27.
-
(2002)
Exp Cell Res
, vol.279
, pp. 118-127
-
-
Yoshimoto, Y.1
Imoto, M.2
-
20
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
Tzung SP, Kim KM, Basanez G et al. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nat Cell Biol 2001; 3: 183-91.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 183-191
-
-
Tzung, S.P.1
Kim, K.M.2
Basanez, G.3
-
21
-
-
28844473501
-
Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus
-
Takemoto Y, Watanabe H, Uchida K et al. Chemistry and biology of moverastins, inhibitors of cancer cell migration, produced by Aspergillus. Chem Biol 2005; 12: 1337-47.
-
(2005)
Chem Biol
, vol.12
, pp. 1337-1347
-
-
Takemoto, Y.1
Watanabe, H.2
Uchida, K.3
-
22
-
-
31444454220
-
Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells
-
Tsuchiya A, Tashiro E, Yoshida M, Imoto M. Involvement of nuclear accumulation of heat shock protein 27 in leptomycin B-induced apoptosis in HeLa cells. J Antibiotics 2005; 58: 810-16.
-
(2005)
J Antibiotics
, vol.58
, pp. 810-816
-
-
Tsuchiya, A.1
Tashiro, E.2
Yoshida, M.3
Imoto, M.4
-
23
-
-
0000222386
-
Depsipeptides from Metarhizium anisopliae
-
Païs M, Das BC, Ferron P. Depsipeptides from Metarhizium anisopliae. Phytochemistry 1981; 20: 715-23.
-
(1981)
Phytochemistry
, vol.20
, pp. 715-723
-
-
Païs, M.1
Das, B.C.2
Ferron, P.3
-
25
-
-
0021678693
-
Isolation and characterization of concanamycins A, B and C
-
Kinashi H, Someno K, Sakaguchi K. Isolation and characterization of concanamycins A, B and C. The J Antibiotics 1984; 37: 1333-43.
-
(1984)
The J Antibiotics
, vol.37
, pp. 1333-1343
-
-
Kinashi, H.1
Someno, K.2
Sakaguchi, K.3
-
27
-
-
32544448056
-
Role of mitochondria as the gardens of cell death
-
Kim R, Emi M, Tanabe K. Role of mitochondria as the gardens of cell death. Cancer Chemother Pharmacol 2006; 57: 545-53.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 545-553
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
-
28
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997; 89: 175-84.
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
29
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998; 391: 96-9.
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
31
-
-
0036481562
-
+ -ATPases -nature's most versatile proton pumps
-
+-ATPases-nature's most versatile proton pumps. Nat Rev Mol Cell Biol 2002; 3: 94-103.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 94-103
-
-
Nishi, T.1
Forgac, M.2
-
33
-
-
33847377377
-
Tumor acidity, chemoresistance and proton pump inhibitors
-
De Milito A, Fais S. Tumor acidity, chemoresistance and proton pump inhibitors. Future Oncol 2005; 1: 779-86.
-
(2005)
Future Oncol
, vol.1
, pp. 779-786
-
-
De Milito, A.1
Fais, S.2
-
34
-
-
23044467723
-
The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump
-
Lu X, Qin W, Li J et al. The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump. Cancer Res 2005; 65: 6843-9.
-
(2005)
Cancer Res
, vol.65
, pp. 6843-6849
-
-
Lu, X.1
Qin, W.2
Li, J.3
-
35
-
-
0037147147
-
Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha
-
Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL. Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. J Biol Chem 2002; 277: 49 569-76.
-
(2002)
J Biol Chem
, vol.277
, pp. 49569-49576
-
-
Tafani, M.1
Cohn, J.A.2
Karpinich, N.O.3
Rothman, R.J.4
Russo, M.A.5
Farber, J.L.6
-
36
-
-
0032515874
-
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
-
Hu Y, Benedict MA, Wu D, Inohara N, Nunez G. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci USA 1998; 95: 4386-91.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4386-4391
-
-
Hu, Y.1
Benedict, M.A.2
Wu, D.3
Inohara, N.4
Nunez, G.5
-
37
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L, Gurbuxani S, Susin SA et al. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 2001; 3: 839-43.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
-
38
-
-
23944462470
-
Regulation of the human apoptotic DNase/RNase endonuclease G: Involvement of Hsp70 and ATP
-
Kalinowska M, Garncarz W, Pietrowska M, Garrard WT, Widlak P. Regulation of the human apoptotic DNase/RNase endonuclease G: Involvement of Hsp70 and ATP. Apoptosis 2005; 10: 821-30.
-
(2005)
Apoptosis
, vol.10
, pp. 821-830
-
-
Kalinowska, M.1
Garncarz, W.2
Pietrowska, M.3
Garrard, W.T.4
Widlak, P.5
-
39
-
-
0034608892
-
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
-
Nylandsted J, Rohde M, Brand K, Bastholm L, Elling F, Jaattela M. Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2. Proc Natl Acad Sci USA 2000; 97: 7871-6.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7871-7876
-
-
Nylandsted, J.1
Rohde, M.2
Brand, K.3
Bastholm, L.4
Elling, F.5
Jaattela, M.6
-
40
-
-
39149114079
-
HSP70 and EndoG modulate cell death by heat in human skin keratinocytes in.vitro
-
Chinnathambi S, Tomanek-Chalkley A, Bickenbach JR. HSP70 and EndoG modulate cell death by heat in human skin keratinocytes in.vitro. Cells Tissues Organs 2008; 187: 131-40.
-
(2008)
Cells Tissues Organs
, vol.187
, pp. 131-140
-
-
Chinnathambi, S.1
Tomanek-Chalkley, A.2
Bickenbach, J.R.3
|