In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 8, 2010, Pages 3318-3325

  Matsuo, Alisson L ^a   Silva, Luis S ^a   Torrecilhas, Ana C ^a   Pascoalino, Bruno S ^a   Ramos, Thiago C ^a   Rodrigues, Elaine G ^a   Schenkman, Sergio ^a   Caires, Antonio C F ^b   Travassos, Luiz R ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 ETHANEBIS(DIPHENYLPHOSPHINE); BENZNIDAZOLE; N,N DIMETHYL 1 PHENETHYLAMINE; PALLADIUM COMPLEX; PHENETHYLAMINE; PHOSPHINE DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INVASION; CHAGAS DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; DRUG TOLERABILITY; FEMALE; HOST PARASITE INTERACTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARASITE DEVELOPMENT; PRIORITY JOURNAL; SINGLE DRUG DOSE; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ANIMALS; CELL LINE; CHAGAS DISEASE; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NITROIMIDAZOLES; PALLADIUM; PARASITIC SENSITIVITY TESTS; TREATMENT OUTCOME; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 77955352809     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00323-10     Document Type: Article

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