Short report: Benznidazole efficacy among Trypanosoma cruzi-infected adolescents after a six-year follow-up

American Journal of Tropical Medicine and Hygiene

Volumn 71, Issue 5, 2004, Pages 594-597

  Andrade, Ana Lucia S S ^a   Martelli, Celina M T ^a   Oliveira, Renato M ^a   Silva, Simonne A ^a   Aires, Andréa I S ^a   Soussumi, Lea M T ^b   Covas, Dimas T ^b   Silva, Luiz S ^c   Andrade, João G ^a   Travassos, Luiz R ^c   Almeida, Igor C ^d  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^b Fundacao Hemocentro de Ribeirao Preto   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ANTIPROTOZOAL AGENT; BENZNIDAZOLE; MUCIN; PLACEBO;

ADOLESCENT DISEASE; ANTIGEN PURIFICATION; ARTICLE; CARDIOMYOPATHY; CHEMOLUMINESCENCE; CHEMOTHERAPY; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG INDICATION; ELECTROCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FOLLOW UP; HUMAN; LONG TERM CARE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS; TRYPOMASTIGOTE;

TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 10044268612     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2004.71.594     Document Type: Article

References (7)

1. World Health Organization. Chagas Disease. Strategic Direction for Research. Available at http://www.who.int/tdr/diseases/ chagas/. Accessed March 10, 2004.
2. de Andrade AL, Zicker F, de Oliveira RM, Almeida Silva S, Luquetti A, Travassos LR, Almeida IC, de Andrade SS, de Andrade JG, Martelli CMT, 1996. Randomised trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection. Lancet 348: 1407-1413.
3. Sosa Estani S, Segura EL, Ruiz AM, Velazquez E, Porcel BM, Yampotis C, 1998. Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease. Am J Trop Med Hyg 59: 526-529.
4. Almeida IC, Covas DT, Soussumi LM, Travassos LR, 1997. A highly sensitive and specific chemiluminescent enzyme-linked immunosorbent assay for diagnosis of active Trypanosoma cruzi infection. Transfusion 37: 850-857.
5. Smith PG, 1987. Evaluating interventions against tropical diseases. Int J Epidemiol 16: 159-166.
6. Galvão LMC, Chiari E, Macedo AM, Luquetti AO, Silva SA, Andrade AL, 2003. PCR as a tool for monitoring Trypanosoma cruzi parasitemia in childhood after specific chemotherapy. J Clin Microbiol 41: 5066-5070.
7. de Andrade AL, Zicker F, Rassi A, Rassi AG, Oliveira RM, Silva SA, de Andrade SS, Martelli CMT, 1998. Early electrocardiographic abnormalities in Trypanosoma crazi-seropositive children. Am J Trop Med Hyg 59: 530-534.