A comparative approach linking molecular dynamics of altered peptide ligands and MHC with In Vivo immune responses

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Knapp, Bernhard ^a   Omasits, Ulrich ^a   Schreiner, Wolfgang ^a   Epstein, Michelle M ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Universitatsklinik fur Dermatologie   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN BASIC PROTEIN; HLA ANTIGEN CLASS 2; LIGAND; PEPTIDE;

ADAPTIVE IMMUNITY; ALLERGIC ENCEPHALITIS; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIGEN STRUCTURE; ARTICLE; BINDING AFFINITY; BORDETELLA PERTUSSIS; CD4+ T LYMPHOCYTE; COMPUTER MODEL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLOGRAPHY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; IMMUNE RESPONSE; IN VIVO STUDY; MOLECULAR DYNAMICS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; T LYMPHOCYTE; ALLERGIC ENCEPHALOMYELITIS; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; LIGANDS; MICE; MOLECULAR DYNAMICS SIMULATION; MYELIN BASIC PROTEINS; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 77955342515     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011653     Document Type: Article

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