Toward an atomistic understanding of the immune synapse: Large-scale molecular dynamics simulation of a membrane-embedded TCR-pMHC-CD4 complex

Molecular Immunology

Volumn 45, Issue 5, 2008, Pages 1221-1230

  Wan, Shunzhou ^a   Flower, Darren R ^b   Coveney, Peter V ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

High performance computing; Immunological synapse; Molecular dynamics

Indexed keywords

CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ARTICLE; CALCIUM SIGNALING; CELL INTERACTION; CELL JUNCTION; CELL MEMBRANE; FLUORESCENCE MICROSCOPY; IMMUNE SYNAPSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MODEL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; SIMULATION; SYNAPSE; THERMODYNAMICS;

ANTIGENS, CD4; COMPUTER SIMULATION; HUMANS; INTERCELLULAR JUNCTIONS; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE PROTEINS; MODELS, CHEMICAL; MOTION; MULTIPROTEIN COMPLEXES; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 37349112664     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.09.022     Document Type: Article

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