A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99

Journal of Molecular Graphics and Modelling

Volumn 25, Issue 1, 2006, Pages 17-29

  Mantzourani, E D ^a,b   Tselios, T V ^b   Grdadolnik, S Golič ^c   Brancale, A ^d   Platts, J A ^e   Matsoukas, J M ^b   Mavromoustakos, T M ^a  

^a INSTITUTE OF BIOLOGY   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

^c NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Arg91, Ala96 MBP87 99; Bioactive conformation; Major histocompatibility complex; Molecular dynamics; NMR; T cell receptor

Indexed keywords

BIOACTIVE CONFORMATION; MAJOR HISTOCOMPATIBILITY COMPLEX; T-CELL RECEPTOR;

COMPUTER SIMULATION; CONFORMATIONS; IMMUNOLOGY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYPEPTIDES;

PROTEINS;

ALANINE; ARGININE; ASPARTIC ACID; HISTIDINE; ISOLEUCINE; MYELIN BASIC PROTEIN; MYELIN BASIC PROTEIN[87-99][91 ARGININE 96 ALANINE]; PEPTIDE DERIVATIVE; PHENYLALANINE; PROLINE; T LYMPHOCYTE RECEPTOR; THREONINE; UNCLASSIFIED DRUG; VALINE;

ALLERGIC ENCEPHALOMYELITIS; AMINO TERMINAL SEQUENCE; ARTICLE; CALCULATION; CONFORMATION; CRYSTAL STRUCTURE; DRUG SYNTHESIS; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN STRUCTURE; THEORETICAL MODEL;

AMINO ACID SEQUENCE; AMINO ACIDS, AROMATIC; ANIMALS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION;

EID: 33748599264     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2005.09.010     Document Type: Article

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