Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231

Journal of Ethnopharmacology

Volumn 131, Issue 1, 2010, Pages 95-103

  Bui Xuan, Ngoc Ha ^a   Tang, Patrick Ming Kuen ^a,d   Wong, Chun Kwok ^b,c   Fung, Kwok Pui ^a,c  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apoptosis; Autophagy; Breast cancer; MAPKs; Pheophorbide a; Photodynamic therapy

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHEOPHORBIDE A; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; DNA DEGRADATION; DRUG CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; RAT; SCUTELLARIA; SCUTELLARIA BARBATA;

SCUTELLARIA BARBATA;

EID: 77955323884     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.06.007     Document Type: Article

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