Evidence that photoactivated pheophorbide a causes in human cancer cells a photodynamic effect involving lipid peroxidation

Cancer Biology and Therapy

Volumn 8, Issue 14, 2009, Pages 1318-1327

  Rapozzi, Valentina ^a   Miculan, Mara ^a   Xodo, Luigi E ^a  

^a Section of Oncology and Molecular Pathology   (Italy)

Author keywords

Glutathione S transferase; Heme oxygenase; HepG2 and HeLa cells; Lipid peroxidation; PDT; Pheophorbide a

Indexed keywords

BAFILOMYCIN A1; DOXYCYCLINE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; HEME OXYGENASE 1; MALONALDEHYDE; PHEOPHORBIDE A; PHOTOSENSITIZING AGENT; SMALL INTERFERING RNA; TAMOXIFEN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; CHLOROPHYLL; DRUG DERIVATIVE; GSTA1 PROTEIN, HUMAN; HMOX1 PROTEIN, HUMAN; RADIOSENSITIZING AGENT; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER THERAPY; CELL CYCLE ARREST; CELL DEATH; CELL PROLIFERATION; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IRRADIATION; LIPID OXIDATION; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; TUMOR CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; GENETICS; IC 50; LIVER CELL CARCINOMA; LIVER TUMOR; PATHOLOGY; PHOTOCHEMOTHERAPY; PHYSIOLOGY; RADIATION EXPOSURE; RNA INTERFERENCE;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHLOROPHYLL; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; GLUTATHIONE TRANSFERASE; HELA CELLS; HEME OXYGENASE-1; HUMANS; INHIBITORY CONCENTRATION 50; LIPID PEROXIDATION; LIVER NEOPLASMS; NEOPLASM PROTEINS; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; RADIATION-SENSITIZING AGENTS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 68149149783     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.14.8628     Document Type: Article

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