Efficient affinity maturation of antibodies in an engineered chicken B cell line DT40-SW by increasing point mutation

Journal of Bioscience and Bioengineering

Volumn 110, Issue 3, 2010, Pages 351-358

  Kajita, Masamichi ^a   Okazawa, Takahiro ^a   Ikeda, Mika ^a   Todo, Kagefumi ^a   Magari, Masaki ^a   Kanayama, Naoki ^a   Ohmori, Hitoshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Affinity maturation; Antibody; Chicken B cell line DT40; Gene conversion; Point mutation; XRCC3

Indexed keywords

ANIMALS; ANTIBODIES; CELL CULTURE; MACHINERY;

AFFINITY MATURATION; B CELLS; GENE CONVERSION; POINT MUTATIONS; XRCC3;

GENES;

MONOCLONAL ANTIBODY; XRCC3 PROTEIN;

ANIMAL CELL; ANTIBODY AFFINITY; ARTICLE; B LYMPHOCYTE; BIOENGINEERING; CHICKEN; CONTROLLED STUDY; GENE CONVERSION; GENE DISRUPTION; GENE TARGETING; NONHUMAN; POINT MUTATION; WILD TYPE;

EID: 77955321545     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2010.03.006     Document Type: Article

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