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Volumn 10, Issue , 2010, Pages

RNA Interference inhibits Hepatitis B Virus of different genotypes in Vitro and in Vivo

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B(E) ANTIGEN; SHORT HAIRPIN RNA; VIRUS DNA; VIRUS RNA; SMALL INTERFERING RNA; VIRUS PROTEIN;

EID: 77955301529     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-10-214     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • 10.1056/NEJM199712113372406. 9392700
    • Hepatitis B virus infection. WM Lee, N Engl J Med 1997 337 24 1733 1745 10.1056/NEJM199712113372406 9392700
    • (1997) N Engl J Med , vol.337 , Issue.24 , pp. 1733-1745
    • Lee, W.M.1
  • 2
    • 0019451351 scopus 로고
    • Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan
    • 10.1016/S0140-6736(81)90585-7. 6118576
    • Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan. RP Beasley LY Hwang CC Lin CS Chien, Lancet 1981 2 8256 1129 1133 10.1016/S0140-6736(81)90585-7 6118576
    • (1981) Lancet , vol.2 , Issue.8256 , pp. 1129-1133
    • Beasley, R.P.1    Hwang, L.Y.2    Lin, C.C.3    Chien, C.S.4
  • 3
    • 0344959603 scopus 로고    scopus 로고
    • Strategies to prevent and control hepatitis B and C virus infections: A global perspective
    • 10.1016/S0264-410X(98)00415-0. 10194830
    • Strategies to prevent and control hepatitis B and C virus infections: a global perspective. EE Mast MJ Alter HS Margolis, Vaccine 1999 17 13-14 1730 1733 10.1016/S0264-410X(98)00415-0 10194830
    • (1999) Vaccine , vol.17 , Issue.13-14 , pp. 1730-1733
    • Mast, E.E.1    Alter, M.J.2    Margolis, H.S.3
  • 4
    • 0027976744 scopus 로고
    • Clinical toxicity of the interferons
    • 10.2165/00002018-199410020-00003. 7516663
    • Clinical toxicity of the interferons. T Vial J Descotes, Drug Saf 1994 10 2 115 150 10.2165/00002018-199410020-00003 7516663
    • (1994) Drug Saf , vol.10 , Issue.2 , pp. 115-150
    • Vial, T.1    Descotes, J.2
  • 5
    • 0030039651 scopus 로고    scopus 로고
    • A survey of adverse events in 11,241 patients with chronic viral hepatitis treated with alfa interferon
    • 10.1016/S0168-8278(96)80184-X. 8834023
    • A survey of adverse events in 11,241 patients with chronic viral hepatitis treated with alfa interferon. G Fattovich G Giustina S Favarato A Ruol, J Hepatol 1996 24 1 38 47 10.1016/S0168-8278(96)80184-X 8834023
    • (1996) J Hepatol , vol.24 , Issue.1 , pp. 38-47
    • Fattovich, G.1    Giustina, G.2    Favarato, S.3    Ruol, A.4
  • 6
    • 67649224111 scopus 로고    scopus 로고
    • Antiviral therapy of chronic hepatitis B: Opportunities and challenges in Asia
    • 10.1016/j.jhep.2009.04.003. 19467727
    • Antiviral therapy of chronic hepatitis B: opportunities and challenges in Asia. YF Liaw, J Hepatol 2009 51 2 403 410 10.1016/j.jhep.2009.04.003 19467727
    • (2009) J Hepatol , vol.51 , Issue.2 , pp. 403-410
    • Liaw, Y.F.1
  • 7
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • 10.1038/35888. 9486653
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. A Fire S Xu MK Montgomery SA Kostas SE Driver CC Mello, Nature 1998 391 6669 806 811 10.1038/35888 9486653
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 8
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • 10.1038/35078107. 11373684
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. SM Elbashir J Harborth W Lendeckel A Yalcin K Weber T Tuschl, Nature 2001 411 6836 494 498 10.1038/35078107 11373684
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 9
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • 10.1101/gad.981002. 11959843
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. PJ Paddison AA Caudy E Bernstein GJ Hannon DS Conklin, Genes Dev 2002 16 8 948 958 10.1101/gad.981002 11959843
    • (2002) Genes Dev , vol.16 , Issue.8 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 10
    • 70349462531 scopus 로고    scopus 로고
    • RNA interference inhibitors of hepatitis B virus
    • 10.1111/j.1749-6632.2009.04974.x. 19796073
    • RNA interference inhibitors of hepatitis B virus. AP McCaffrey, Ann N Y Acad Sci 2009 1175 15 23 10.1111/j.1749-6632.2009.04974.x 19796073
    • (2009) Ann N y Acad Sci , vol.1175 , pp. 15-23
    • McCaffrey, A.P.1
  • 11
    • 70449512070 scopus 로고    scopus 로고
    • Hepatitis B Virus Inhibition in Mice by Lentiviral Vector Mediated Small Interference RNA
    • 10.1186/1471-230X-9-73. 19804649
    • Hepatitis B Virus Inhibition in Mice by Lentiviral Vector Mediated Small Interference RNA. L Deng G Li L Xi A Yin Y Gao W You X Wang B Sun, BMC Gastroenterol 2009 9 1 73 10.1186/1471-230X-9-73 19804649
    • (2009) BMC Gastroenterol , vol.9 , Issue.1 , pp. 73
    • Deng, L.1    Li, G.2    Xi, L.3    Yin, A.4    Gao, Y.5    You, W.6    Wang, X.7    Sun, B.8
  • 12
    • 0037108818 scopus 로고    scopus 로고
    • Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
    • 10.1073/pnas.202398599. 12374864
    • Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. PL Yang A Althage J Chung FV Chisari, Proc Natl Acad Sci USA 2002 99 21 13825 13830 10.1073/pnas.202398599 12374864
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.21 , pp. 13825-13830
    • Yang, P.L.1    Althage, A.2    Chung, J.3    Chisari, F.V.4
  • 14
    • 0037382795 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus expression and replication by RNA interference
    • 10.1053/jhep.2003.50146. 12668968
    • Inhibition of hepatitis B virus expression and replication by RNA interference. A Shlomai Y Shaul, Hepatology 2003 37 4 764 770 10.1053/jhep.2003.50146 12668968
    • (2003) Hepatology , vol.37 , Issue.4 , pp. 764-770
    • Shlomai, A.1    Shaul, Y.2
  • 15
    • 33846124558 scopus 로고    scopus 로고
    • Hepatitis B virus is inhibited by RNA interference in cell culture and in mice
    • 10.1016/j.antiviral.2006.05.022. 16844238
    • Hepatitis B virus is inhibited by RNA interference in cell culture and in mice. RS Ying C Zhu XG Fan N Li XF Tian HB Liu BX Zhang, Antiviral Res 2007 73 1 24 30 10.1016/j.antiviral.2006.05.022 16844238
    • (2007) Antiviral Res , vol.73 , Issue.1 , pp. 24-30
    • Ying, R.S.1    Zhu, C.2    Fan, X.G.3    Li, N.4    Tian, X.F.5    Liu, H.B.6    Zhang, B.X.7
  • 16
    • 0346873025 scopus 로고    scopus 로고
    • Small interfering RNA inhibits hepatitis B virus replication in mice
    • 10.1016/S1525-0016(03)00244-2. 14599810
    • Small interfering RNA inhibits hepatitis B virus replication in mice. H Giladi M Ketzinel-Gilad L Rivkin Y Felig O Nussbaum E Galun, Mol Ther 2003 8 5 769 776 10.1016/S1525-0016(03)00244-2 14599810
    • (2003) Mol Ther , vol.8 , Issue.5 , pp. 769-776
    • Giladi, H.1    Ketzinel-Gilad, M.2    Rivkin, L.3    Felig, Y.4    Nussbaum, O.5    Galun, E.6
  • 17
    • 38049161918 scopus 로고    scopus 로고
    • RNAi for treating hepatitis B viral infection
    • 10.1007/s11095-007-9504-0. 18074201
    • RNAi for treating hepatitis B viral infection. Y Chen G Cheng RI Mahato, Pharm Res 2008 25 1 72 86 10.1007/s11095-007-9504-0 18074201
    • (2008) Pharm Res , vol.25 , Issue.1 , pp. 72-86
    • Chen, Y.1    Cheng, G.2    Mahato, R.I.3
  • 18
    • 44349178186 scopus 로고    scopus 로고
    • Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo
    • 10.1038/mt.2008.82. 18431360
    • Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo. A Ely T Naidoo S Mufamadi C Crowther P Arbuthnot, Mol Ther 2008 16 6 1105 1112 10.1038/mt.2008.82 18431360
    • (2008) Mol Ther , vol.16 , Issue.6 , pp. 1105-1112
    • Ely, A.1    Naidoo, T.2    Mufamadi, S.3    Crowther, C.4    Arbuthnot, P.5
  • 20
    • 43949090856 scopus 로고    scopus 로고
    • New complex recombinant genotype of hepatitis B virus identified in Vietnam
    • 10.1128/JVI.02556-07. 18353958
    • New complex recombinant genotype of hepatitis B virus identified in Vietnam. TT Tran TN Trinh K Abe, J Virol 2008 82 11 5657 5663 10.1128/JVI.02556-07 18353958
    • (2008) J Virol , vol.82 , Issue.11 , pp. 5657-5663
    • Tran, T.T.1    Trinh, T.N.2    Abe, K.3
  • 21
    • 67349263842 scopus 로고    scopus 로고
    • Detection of a newly identified hepatitis B virus genotype in southeastern France
    • 10.1016/j.jcv.2009.03.007. 19376743
    • Detection of a newly identified hepatitis B virus genotype in southeastern France. P Colson B Roquelaure C Tamalet, J Clin Virol 2009 45 2 165 167 10.1016/j.jcv.2009.03.007 19376743
    • (2009) J Clin Virol , vol.45 , Issue.2 , pp. 165-167
    • Colson, P.1    Roquelaure, B.2    Tamalet, C.3
  • 22
    • 33750633962 scopus 로고    scopus 로고
    • Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens
    • 10.1002/hep.21345. 17006908
    • Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens. M Sugiyama Y Tanaka T Kato E Orito K Ito SK Acharya RG Gish A Kramvis T Shimada N Izumi, et al. Hepatology 2006 44 4 915 924 10.1002/hep.21345 17006908
    • (2006) Hepatology , vol.44 , Issue.4 , pp. 915-924
    • Sugiyama, M.1    Tanaka, Y.2    Kato, T.3    Orito, E.4    Ito, K.5    Acharya, S.K.6    Gish, R.G.7    Kramvis, A.8    Shimada, T.9    Izumi, N.10
  • 24
    • 0032692170 scopus 로고    scopus 로고
    • RNA-polymerase III-driven expression cassettes in human gene therapy
    • 11249665
    • RNA-polymerase III-driven expression cassettes in human gene therapy. MF Medina S Joshi, Curr Opin Mol Ther 1999 1 5 580 594 11249665
    • (1999) Curr Opin Mol Ther , vol.1 , Issue.5 , pp. 580-594
    • Medina, M.F.1    Joshi, S.2
  • 25
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • 10.1038/nature04791. 16724069
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. D Grimm KL Streetz CL Jopling TA Storm K Pandey CR Davis P Marion F Salazar MA Kay, Nature 2006 441 7092 537 541 10.1038/nature04791 16724069
    • (2006) Nature , vol.441 , Issue.7092 , pp. 537-541
    • Grimm, D.1    Streetz, K.L.2    Jopling, C.L.3    Storm, T.A.4    Pandey, K.5    Davis, C.R.6    Marion, P.7    Salazar, F.8    Kay, M.A.9
  • 26
    • 61649128003 scopus 로고    scopus 로고
    • Rational design leads to more potent RNA interference against hepatitis B virus: Factors effecting silencing efficiency
    • 10.1038/mt.2008.273. 19088704
    • Rational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency. K Keck EM Volper RM Spengler DD Long CY Chan Y Ding AP McCaffrey, Mol Ther 2009 17 3 538 547 10.1038/mt.2008.273 19088704
    • (2009) Mol Ther , vol.17 , Issue.3 , pp. 538-547
    • Keck, K.1    Volper, E.M.2    Spengler, R.M.3    Long, D.D.4    Chan, C.Y.5    Ding, Y.6    McCaffrey, A.P.7
  • 27
    • 0021990056 scopus 로고
    • Quantitation of hepatitis B virus (HBV) core antigen in serum in the presence of antibodies to HBV core antigen: Comparison with assays of serum HBV DNA, DNA polymerase, and HBV e antigen
    • 3988901
    • Quantitation of hepatitis B virus (HBV) core antigen in serum in the presence of antibodies to HBV core antigen: comparison with assays of serum HBV DNA, DNA polymerase, and HBV e antigen. R Bredehorst H von Wulffen C Granato, J Clin Microbiol 1985 21 4 593 598 3988901
    • (1985) J Clin Microbiol , vol.21 , Issue.4 , pp. 593-598
    • Bredehorst, R.1    Von Wulffen, H.2    Granato, C.3
  • 28
    • 0038290377 scopus 로고    scopus 로고
    • New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA
    • 10.1128/JCM.41.5.1901-1906.2003. 12734224
    • New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA. T Kimura A Rokuhara A Matsumoto S Yagi E Tanaka K Kiyosawa N Maki, J Clin Microbiol 2003 41 5 1901 1906 10.1128/JCM.41.5.1901-1906.2003 12734224
    • (2003) J Clin Microbiol , vol.41 , Issue.5 , pp. 1901-1906
    • Kimura, T.1    Rokuhara, A.2    Matsumoto, A.3    Yagi, S.4    Tanaka, E.5    Kiyosawa, K.6    Maki, N.7
  • 29
    • 19944428132 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomised trial
    • 10.1016/S0140-6736(05)17701-0. 15639293
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. HL Janssen M van Zonneveld H Senturk S Zeuzem US Akarca Y Cakaloglu C Simon TM So G Gerken RA de Man, et al. Lancet 2005 365 9454 123 129 10.1016/S0140-6736(05)17701-0 15639293
    • (2005) Lancet , vol.365 , Issue.9454 , pp. 123-129
    • Janssen, H.L.1    Van Zonneveld, M.2    Senturk, H.3    Zeuzem, S.4    Akarca, U.S.5    Cakaloglu, Y.6    Simon, C.7    So, T.M.8    Gerken, G.9    De Man, R.A.10
  • 30
    • 67649467313 scopus 로고    scopus 로고
    • EASL clinical practice guidelines. Management of chronic hepatitis B
    • 10.1016/j.gcb.2009.03.002. 19481389
    • [EASL clinical practice guidelines. Management of chronic hepatitis B]. EASL, Gastroenterol Clin Biol 2009 33 6-7 539 554 10.1016/j.gcb.2009.03.002 19481389
    • (2009) Gastroenterol Clin Biol , vol.33 , Issue.6-7 , pp. 539-554
  • 31
    • 67349145735 scopus 로고    scopus 로고
    • EASL clinical practice guidelines on the management of chronic hepatitis B: The need for liver biopsy
    • 10.1016/j.jhep.2009.02.017. 19410321
    • EASL clinical practice guidelines on the management of chronic hepatitis B: the need for liver biopsy. GV Papatheodoridis S Manolakopoulos, J Hepatol 2009 51 1 226 227 10.1016/j.jhep.2009.02.017 19410321
    • (2009) J Hepatol , vol.51 , Issue.1 , pp. 226-227
    • Papatheodoridis, G.V.1    Manolakopoulos, S.2
  • 32
    • 34548316974 scopus 로고    scopus 로고
    • AASLD Practice Guidelines on chronic hepatitis B and HBV infection in Italy
    • author reply 609. 10.1002/hep.21841. 17661422
    • AASLD Practice Guidelines on chronic hepatitis B and HBV infection in Italy. T Stroffolini GB Gaeta A Mele, Hepatology 2007 46 2 608 609 author reply 609 10.1002/hep.21841 17661422
    • (2007) Hepatology , vol.46 , Issue.2 , pp. 608-609
    • Stroffolini, T.1    Gaeta, G.B.2    Mele, A.3
  • 33
    • 34250674546 scopus 로고    scopus 로고
    • Opportunities for treating chronic hepatitis B and C virus infection using RNA interference
    • 10.1111/j.1365-2893.2006.00818.x. 17576386
    • Opportunities for treating chronic hepatitis B and C virus infection using RNA interference. P Arbuthnot V Longshaw T Naidoo MS Weinberg, J Viral Hepat 2007 14 7 447 459 10.1111/j.1365-2893.2006.00818.x 17576386
    • (2007) J Viral Hepat , vol.14 , Issue.7 , pp. 447-459
    • Arbuthnot, P.1    Longshaw, V.2    Naidoo, T.3    Weinberg, M.S.4
  • 34
    • 22544447827 scopus 로고    scopus 로고
    • Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors
    • 10.1002/jgm.739. 15756649
    • Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors. MD Moore MJ McGarvey RA Russell BR Cullen MO McClure, J Gene Med 2005 7 7 918 925 10.1002/jgm.739 15756649
    • (2005) J Gene Med , vol.7 , Issue.7 , pp. 918-925
    • Moore, M.D.1    McGarvey, M.J.2    Russell, R.A.3    Cullen, B.R.4    McClure, M.O.5
  • 35
    • 0038731180 scopus 로고    scopus 로고
    • Short interfering RNA-directed inhibition of hepatitis B virus replication
    • 10.1016/S0014-5793(03)00400-9. 12753904
    • Short interfering RNA-directed inhibition of hepatitis B virus replication. K Hamasaki K Nakao K Matsumoto T Ichikawa H Ishikawa K Eguchi, FEBS Lett 2003 543 1-3 51 54 10.1016/S0014-5793(03)00400-9 12753904
    • (2003) FEBS Lett , vol.543 , Issue.1-3 , pp. 51-54
    • Hamasaki, K.1    Nakao, K.2    Matsumoto, K.3    Ichikawa, T.4    Ishikawa, H.5    Eguchi, K.6
  • 37
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • 10.1126/science.1068999. 11910072
    • A system for stable expression of short interfering RNAs in mammalian cells. TR Brummelkamp R Bernards R Agami, Science 2002 296 5567 550 553 10.1126/science.1068999 11910072
    • (2002) Science , vol.296 , Issue.5567 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 38
    • 16344396086 scopus 로고    scopus 로고
    • Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo
    • 10.1158/1078-0432.CCR-04-1129. 15756028
    • Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. T Shiokawa Y Hattori K Kawano Y Ohguchi H Kawakami K Toma Y Maitani, Clin Cancer Res 2005 11 5 2018 2025 10.1158/1078-0432.CCR-04-1129 15756028
    • (2005) Clin Cancer Res , vol.11 , Issue.5 , pp. 2018-2025
    • Shiokawa, T.1    Hattori, Y.2    Kawano, K.3    Ohguchi, Y.4    Kawakami, H.5    Toma, K.6    Maitani, Y.7
  • 39
    • 0029803056 scopus 로고    scopus 로고
    • A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet
    • 8951178
    • A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. M Ishiyama H Tominaga M Shiga K Sasamoto Y Ohkura K Ueno, Biol Pharm Bull 1996 19 11 1518 1520 8951178
    • (1996) Biol Pharm Bull , vol.19 , Issue.11 , pp. 1518-1520
    • Ishiyama, M.1    Tominaga, H.2    Shiga, M.3    Sasamoto, K.4    Ohkura, Y.5    Ueno, K.6
  • 40
    • 77952425411 scopus 로고    scopus 로고
    • Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites
    • 10.1016/j.jhep.2009.10.038. 20400195
    • Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites. D Sun C Rosler K Kidd-Ljunggren M Nassal, J Hepatol 2010 52 6 817 826 10.1016/j.jhep.2009.10.038 20400195
    • (2010) J Hepatol , vol.52 , Issue.6 , pp. 817-826
    • Sun, D.1    Rosler, C.2    Kidd-Ljunggren, K.3    Nassal, M.4
  • 42
    • 84984535216 scopus 로고    scopus 로고
    • Identification of androgen response elements in the enhancer i of hepatitis B virus: A mechanism for sex disparity in chronic hepatitis B
    • Identification of androgen response elements in the enhancer I of hepatitis B virus: A mechanism for sex disparity in chronic hepatitis B. SH Wang SH Yeh WH Lin HY Wang DS Chen PJ Chen, Hepatology 2009
    • (2009) Hepatology
    • Wang, S.H.1    Yeh, S.H.2    Lin, W.H.3    Wang, H.Y.4    Chen, D.S.5    Chen, P.J.6
  • 43
    • 35348840226 scopus 로고    scopus 로고
    • Replicative competence of the T131I, K141E, and G145R surface variants of hepatitis B Virus
    • 10.1086/521198. 17763322
    • Replicative competence of the T131I, K141E, and G145R surface variants of hepatitis B Virus. S Jammeh HC Thomas P Karayiannis, J Infect Dis 2007 196 7 1010 1013 10.1086/521198 17763322
    • (2007) J Infect Dis , vol.196 , Issue.7 , pp. 1010-1013
    • Jammeh, S.1    Thomas, H.C.2    Karayiannis, P.3


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