A novel pharmacophore model for the design of anthrax lethal factor inhibitors

Chemical Biology and Drug Design

Volumn 76, Issue 3, 2010, Pages 263-268

  Yuan, Hongbin ^a   Johnson, Sherida L ^a   Chen, Li Hsing ^a   Wei, Jun ^a   Pellecchia, Maurizio ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Anthrax; drug design; LF; Pharmacophore

Indexed keywords

ANTHRAX TOXIN; GELATINASE A; GELATINASE B; METALLOPROTEINASE INHIBITOR;

ANTHRAX; ARTICLE; CONFORMATIONAL TRANSITION; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL;

ANTHRAX; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CRYSTALLOGRAPHY, X-RAY; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; METALLOPROTEASES; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955242489     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.01000.x     Document Type: Article

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