메뉴 건너뛰기




Volumn 16, Issue 8, 2010, Pages 1570-1583

DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures

Author keywords

DiGeorge syndrome; MicroRNA processing; Molecular recognition; Ribonuclease III; RNA binding protein

Indexed keywords

MICRORNA; MICRORNA 21; PROTEIN DGCR8; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 77955119567     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2111310     Document Type: Article
Times cited : (52)

References (48)
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. 2009. MicroRNAs: Target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 5
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • Croce CM. 2009. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10: 704-714.
    • (2009) Nat Rev Genet , vol.10 , pp. 704-714
    • Croce, C.M.1
  • 7
    • 55049137165 scopus 로고    scopus 로고
    • MicroRNA biogenesis: There's more than one way to skin a cat
    • Faller M, Guo F. 2008. MicroRNA biogenesis: There's more than one way to skin a cat. Biochim Biophys Acta 1779: 663-667.
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 663-667
    • Faller, M.1    Guo, F.2
  • 9
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. 2008. Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat Rev Genet 9: 102-114.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 12
    • 34447115822 scopus 로고    scopus 로고
    • The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
    • Guil S, Caceres JF. 2007. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 14: 591-596.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 591-596
    • Guil, S.1    Caceres, J.F.2
  • 13
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN. 2004. The Drosha- DGCR8 complex in primary microRNA processing. Genes Dev 18: 3016-3027.
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 16
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor microRNA
    • Heo I, Joo C, Cho J, Ha M, Han J, Kim VN. 2008. Lin28 mediates the terminal uridylation of let-7 precursor microRNA. Mol Cell 32: 276-284.
    • (2008) Mol Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 18
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. 2007. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39: 673-677.
    • (2007) Nat Genet , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 19
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. 2001. Identification of novel genes coding for small expressed RNAs. Science 294: 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 21
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • DOI 10.1016/j.cub.2004.11.001, PII S0960982204008693
    • Landthaler M, Yalcin A, Tuschl T. 2004. The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14: 2162-2167. (Pubitemid 39623200)
    • (2004) Current Biology , vol.14 , Issue.23 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 22
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau NC, Lim LP, Weinstein EG, Bartel DP. 2001. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 23
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee RC, Ambros V. 2001. An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 24
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • DOI 10.1093/emboj/cdf476
    • Lee Y, Jeon K, Lee JT, Kim S, Kim VN. 2002. MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J 21: 4663-4670. (Pubitemid 34984353)
    • (2002) EMBO Journal , vol.21 , Issue.17 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.-T.3    Kim, S.4    Kim, V.N.5
  • 27
    • 0033377664 scopus 로고    scopus 로고
    • EMAN: Semiautomated software for high-resolution single-particle reconstructions
    • DOI 10.1006/jsbi.1999.4174
    • Ludtke SJ, Baldwin PR, Chiu W. 1999. EMAN: Semiautomated software for high-resolution single-particle reconstructions. J Struct Biol 128: 82-97. (Pubitemid 30013436)
    • (1999) Journal of Structural Biology , vol.128 , Issue.1 , pp. 82-97
    • Ludtke, S.J.1    Baldwin, P.R.2    Chiu, W.3
  • 29
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman MA, Thomson JM, Hammond SM. 2008. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 14: 1539-1549.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 30
    • 73449134082 scopus 로고    scopus 로고
    • Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography
    • Peng L, Ryazantsev S, Sun R, Zhou ZH. 2010. Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography. Structure 18: 47-58.
    • (2010) Structure , vol.18 , pp. 47-58
    • Peng, L.1    Ryazantsev, S.2    Sun, R.3    Zhou, Z.H.4
  • 32
    • 0033511832 scopus 로고    scopus 로고
    • Cell biology of heme
    • Ponka P. 1999. Cell biology of heme. Am J Med Sci 318: 241-256.
    • (1999) Am J Med Sci , vol.318 , pp. 241-256
    • Ponka, P.1
  • 35
    • 0037466486 scopus 로고    scopus 로고
    • Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region
    • DOI 10.1016/S0006-291X(03)00554-0
    • Shiohama A, Sasaki T, Noda S, Minoshima S, Shimizu N. 2003. Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun 304: 184-190. (Pubitemid 36434214)
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , Issue.1 , pp. 184-190
    • Shiohama, A.1    Sasaki, T.2    Noda, S.3    Minoshima, S.4    Shimizu, N.5
  • 40
    • 66449118741 scopus 로고    scopus 로고
    • Post-transcriptional control of DGCR8 expression by the Microprocessor
    • Triboulet R, Chang HM, Lapierre RJ, Gregory RI. 2009. Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA 15: 1005-1011.
    • (2009) RNA , vol.15 , pp. 1005-1011
    • Triboulet, R.1    Chang, H.M.2    Lapierre, R.J.3    Gregory, R.I.4
  • 41
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI. 2008. Selective blockade of microRNA processing by Lin28. Science 320: 97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 42
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • DOI 10.1038/ng1969, PII NG1969
    • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. 2007. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 39: 380-385. (Pubitemid 46328490)
    • (2007) Nature Genetics , vol.39 , Issue.3 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 43
    • 29244462551 scopus 로고    scopus 로고
    • Accurate marker-free alignment with simultaneous geometry determination and reconstruction of tilt series in electron tomography
    • DOI 10.1016/j.ultramic.2005.07.007, PII S0304399105001865
    • Winkler H, Taylor KA. 2006. Accurate marker-free alignment with simultaneous geometry determination and reconstruction of tilt series in electron tomography. Ultramicroscopy 106: 240-254. (Pubitemid 41820581)
    • (2006) Ultramicroscopy , vol.106 , Issue.3 , pp. 240-254
    • Winkler, H.1    Taylor, K.A.2
  • 44
    • 33749984008 scopus 로고    scopus 로고
    • Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing
    • DOI 10.1093/nar/gkl458
    • Yeom KH, Lee Y, Han J, Suh MR, Kim VN. 2006. Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing. Nucleic Acids Res 34: 4622-4629. (Pubitemid 44567057)
    • (2006) Nucleic Acids Research , vol.34 , Issue.16 , pp. 4622-4629
    • Yeom, K.-H.1    Lee, Y.2    Han, J.3    Suh, M.R.4    Kim, V.N.5
  • 46
    • 23044502585 scopus 로고    scopus 로고
    • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
    • DOI 10.1074/jbc.M504714200
    • Zeng Y, Cullen BR. 2005. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J Biol Chem 280: 27595-27603. (Pubitemid 41076871)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.30 , pp. 27595-27603
    • Zeng, Y.1    Cullen, B.R.2
  • 47
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
    • DOI 10.1038/sj.emboj.7600491
    • Zeng Y, Yi R, Cullen BR. 2005. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J 24: 138-148. (Pubitemid 40188471)
    • (2005) EMBO Journal , vol.24 , Issue.1 , pp. 138-148
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 48
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • DOI 10.1093/emboj/cdf582
    • Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W. 2002. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J 21: 5875-5885. (Pubitemid 35315285)
    • (2002) EMBO Journal , vol.21 , Issue.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.