-
1
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
-
Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102-114.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
4
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V (2004) The functions of animal microRNAs. Nature 431:350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
6
-
-
70349320158
-
Causes and consequences of micro-RNA dysregulation in cancer
-
Croce CM (2009) Causes and consequences of micro-RNA dysregulation in cancer. Nat Rev Genet 10: 704-714.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
7
-
-
38349186896
-
MicroRNAs (miRNAs) in neurodegenerative diseases
-
Nelson PT, Wang WX, Rajeev BW (2008) MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol 18:130-138.
-
(2008)
Brain Pathol
, vol.18
, pp. 130-138
-
-
Nelson, P.T.1
Wang, W.X.2
Rajeev, B.W.3
-
9
-
-
55049137165
-
MicroRNA biogenesis: There's more than one way to skin a cat
-
Faller M, Guo F (2008) MicroRNA biogenesis: there's more than one way to skin a cat. Biochim Biophys Acta 1779:663-667.
-
(2008)
Biochim Biophys Acta
, vol.1779
, pp. 663-667
-
-
Faller, M.1
Guo, F.2
-
10
-
-
58749113430
-
A three-dimensional view of the molecular machinery of RNA interference
-
Jinek M, Doudna JA (2009) A three-dimensional view of the molecular machinery of RNA interference. Nature 457:405-412.
-
(2009)
Nature
, vol.457
, pp. 405-412
-
-
Jinek, M.1
Doudna, J.A.2
-
11
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, Kim VN (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
12
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
DOI 10.1038/nature03049
-
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ (2004) Processing of primary microRNAs by the Microprocessor complex. Nature 432:231-235. (Pubitemid 39545854)
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.J.2
Plasterk, R.H.A.3
Ketting, R.F.4
Hannon, G.J.5
-
13
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
DOI 10.1038/nature03120
-
Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R (2004) The Microprocessor complex mediates the genesis of microRNAs. Nature 432:235-240. (Pubitemid 39545855)
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.-P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
14
-
-
10644234841
-
The Drosha-DGCR8 complex in primary micro-RNA processing
-
Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN (2004) The Drosha-DGCR8 complex in primary micro-RNA processing. Genes Dev 18:3016-3027.
-
(2004)
Genes Dev
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
15
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
-
DOI 10.1016/j.cub.2004.11.001, PII S0960982204008693
-
Landthaler M, Yalcin A, Tuschl T (2004) The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14:2162-2167. (Pubitemid 39623200)
-
(2004)
Current Biology
, vol.14
, Issue.23
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
16
-
-
33847323881
-
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
-
DOI 10.1038/ng1969, PII NG1969
-
Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R (2007) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet 39:380-385. (Pubitemid 46328490)
-
(2007)
Nature Genetics
, vol.39
, Issue.3
, pp. 380-385
-
-
Wang, Y.1
Medvid, R.2
Melton, C.3
Jaenisch, R.4
Blelloch, R.5
-
17
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, Sohn SY, Cho Y, Zhang BT, Kim VN (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125:887-901.
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
Sohn, S.Y.7
Cho, Y.8
Zhang, B.T.9
Kim, V.N.10
-
18
-
-
33846065567
-
Heme is involved in microRNA processing
-
Faller M, Matsunaga M, Yin S, Loo JA, Guo F (2007) Heme is involved in microRNA processing. Nat Struct Mol Biol 14:23-29.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 23-29
-
-
Faller, M.1
Matsunaga, M.2
Yin, S.3
Loo, J.A.4
Guo, F.5
-
19
-
-
34548480185
-
Crystal structure of human DGCR8 core
-
DOI 10.1038/nsmb1294, PII NSMB1294
-
Sohn SY, Bae WJ, Kim JJ, Yeom KH, Kim VN, Cho Y (2007) Crystal structure of human DGCR8 core. Nat Struct Mol Biol 14:847-853. (Pubitemid 47373837)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.9
, pp. 847-853
-
-
Sohn, S.Y.1
Bae, W.J.2
Kim, J.J.3
Yeom, K.-H.4
Kim, V.N.5
Cho, Y.6
-
20
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
DOI 10.1038/ng2003, PII NG2003
-
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T (2007) Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39: 673-677. (Pubitemid 46676103)
-
(2007)
Nature Genetics
, vol.39
, Issue.5
, pp. 673-677
-
-
Kumar, M.S.1
Lu, J.2
Mercer, K.L.3
Golub, T.R.4
Jacks, T.5
-
21
-
-
58049213696
-
Dicer, Drosha, and outcomes in patients with ovarian cancer
-
Merritt WM, Lin YG, Han LY, Kamat AA, Spannuth WA, Schmandt R, Urbauer D, Pennacchio LA, Cheng JF, Nick AM, Deavers MT, Mourad-Zeidan A, Wang H, Mueller P, Lenburg ME, Gray JW, Mok S, Birrer MJ, Lopez-Berestein G, Coleman RL, Bar-Eli M, Sood AK (2008) Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med 359:2641-2650.
-
(2008)
N Engl J Med
, vol.359
, pp. 2641-2650
-
-
Merritt, W.M.1
Lin, Y.G.2
Han, L.Y.3
Kamat, A.A.4
Spannuth, W.A.5
Schmandt, R.6
Urbauer, D.7
Pennacchio, L.A.8
Cheng, J.F.9
Nick, A.M.10
Deavers, M.T.11
Mourad-Zeidan, A.12
Wang, H.13
Mueller, P.14
Lenburg, M.E.15
Gray, J.W.16
Mok, S.17
Birrer, M.J.18
Lopez-Berestein, G.19
Coleman, R.L.20
Bar-Eli, M.21
Sood, A.K.22
more..
-
22
-
-
0037466486
-
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region
-
DOI 10.1016/S0006-291X(03)00554-0
-
Shiohama A, Sasaki T, Noda S, Minoshima S, Shimizu N (2003) Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun 304:184-190. (Pubitemid 36434214)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.304
, Issue.1
, pp. 184-190
-
-
Shiohama, A.1
Sasaki, T.2
Noda, S.3
Minoshima, S.4
Shimizu, N.5
-
23
-
-
43949124669
-
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
-
Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills AA, Karayiorgou M, Gogos JA (2008) Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet 40:751-760.
-
(2008)
Nat Genet
, vol.40
, pp. 751-760
-
-
Stark, K.L.1
Xu, B.2
Bagchi, A.3
Lai, W.S.4
Liu, H.5
Hsu, R.6
Wan, X.7
Pavlidis, P.8
Mills, A.A.9
Karayiorgou, M.10
Gogos, J.A.11
-
24
-
-
33749984008
-
Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing
-
DOI 10.1093/nar/gkl458
-
Yeom KH, Lee Y, Han J, Suh MR, Kim VN (2006) Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing. Nucleic Acids Res 34:4622-4629. (Pubitemid 44567057)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.16
, pp. 4622-4629
-
-
Yeom, K.-H.1
Lee, Y.2
Han, J.3
Suh, M.R.4
Kim, V.N.5
-
25
-
-
0036157980
-
The WW domain: Linking cell signalling to the membrane cytoskeleton
-
DOI 10.1016/S0898-6568(01)00236-4, PII S0898656801002364
-
Ilsley JL, Sudol M, Winder SJ (2002) The WW domain: linking cell signalling to the membrane cytoskeleton. Cell Signal 14:183-189. (Pubitemid 34102446)
-
(2002)
Cellular Signalling
, vol.14
, Issue.3
, pp. 183-189
-
-
Ilsley, J.L.1
Sudol, M.2
Winder, S.J.3
-
26
-
-
62349106992
-
Mass spectrometry detection and characterization of noncovalent protein complexes
-
Yin S, Loo JA (2009) Mass spectrometry detection and characterization of noncovalent protein complexes. Methods Mol Biol 492:273-282.
-
(2009)
Methods Mol Biol
, vol.492
, pp. 273-282
-
-
Yin, S.1
Loo, J.A.2
-
27
-
-
0036108484
-
3D domain swapping: As domains continue to swap
-
DOI 10.1110/ps.0201402
-
Liu Y, Eisenberg D (2002) 3D domain swapping: as domains continue to swap. Protein Sci 11:1285-1299. (Pubitemid 34547201)
-
(2002)
Protein Science
, vol.11
, Issue.6
, pp. 1285-1299
-
-
Liu, Y.1
Eisenberg, D.2
-
28
-
-
33846426840
-
Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form
-
Ohnishi S, Guntert P, Koshiba S, Tomizawa T, Akasaka R, Tochio N, Sato M, Inoue M, Harada T, Watanabe S, Tanaka A, Shirouzu M, Kigawa T, Yokoyama S (2007) Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form. FEBS Lett 581: 462-468.
-
(2007)
FEBS Lett
, vol.581
, pp. 462-468
-
-
Ohnishi, S.1
Guntert, P.2
Koshiba, S.3
Tomizawa, T.4
Akasaka, R.5
Tochio, N.6
Sato, M.7
Inoue, M.8
Harada, T.9
Watanabe, S.10
Tanaka, A.11
Shirouzu, M.12
Kigawa, T.13
Yokoyama, S.14
-
29
-
-
0343081091
-
Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan
-
Huang X, Poy F, Zhang R, Joachimiak A, Sudol M, Eck MJ (2000) Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan. Nat Struct Biol 7:634-638.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 634-638
-
-
Huang, X.1
Poy, F.2
Zhang, R.3
Joachimiak, A.4
Sudol, M.5
Eck, M.J.6
-
30
-
-
67749090874
-
Sequence determinants of thermodynamic stability in a WW domain - An all-beta-sheet protein
-
Jager M, Dendle M, Kelly JW (2009) Sequence determinants of thermodynamic stability in a WW domain - an all-beta-sheet protein. Protein Sci 18:1806-1813.
-
(2009)
Protein Sci
, vol.18
, pp. 1806-1813
-
-
Jager, M.1
Dendle, M.2
Kelly, J.W.3
-
32
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
DOI 10.1101/gad.1444406
-
Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM (2006) Extensive posttranscriptional regulation of microRNAs and its implications for cancer. Genes Dev 20:2202-2207. (Pubitemid 44244521)
-
(2006)
Genes and Development
, vol.20
, Issue.16
, pp. 2202-2207
-
-
Thomson, J.M.1
Newman, M.2
Parker, J.S.3
Morin-Kensicki, E.M.4
Wright, T.5
Hammond, S.M.6
-
33
-
-
58149097010
-
Posttranscriptional crossregulation between Drosha and DGCR8
-
Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN (2009) Posttranscriptional crossregulation between Drosha and DGCR8. Cell 136:75-84.
-
(2009)
Cell
, vol.136
, pp. 75-84
-
-
Han, J.1
Pedersen, J.S.2
Kwon, S.C.3
Belair, C.D.4
Kim, Y.K.5
Yeom, K.H.6
Yang, W.Y.7
Haussler, D.8
Blelloch, R.9
Kim, V.N.10
-
34
-
-
66449118741
-
Post-transcriptional control of DGCR8 expression by the Microprocessor
-
Triboulet R, Chang HM, Lapierre RJ, Gregory RI (2009) Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA 15:1005-1011.
-
(2009)
RNA
, vol.15
, pp. 1005-1011
-
-
Triboulet, R.1
Chang, H.M.2
Lapierre, R.J.3
Gregory, R.I.4
-
35
-
-
70349187028
-
Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8
-
Shenoy A, Blelloch R (2009) Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8. PLoS One 4:e6971.
-
(2009)
PLoS One
, vol.4
-
-
Shenoy, A.1
Blelloch, R.2
-
36
-
-
40849108663
-
Selective blockade of microRNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI (2008) Selective blockade of microRNA processing by Lin28. Science 320:97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
37
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo I, Joo C, Cho J, Ha M, Han J, Kim VN (2008) Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 32:276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
Kim, V.N.6
-
38
-
-
4143083663
-
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex
-
DOI 10.1016/j.str.2004.05.023, PII S0969212604002436
-
Reverter D, Lima CD (2004) A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. Structure 12:1519-1531. (Pubitemid 39092096)
-
(2004)
Structure
, vol.12
, Issue.8
, pp. 1519-1531
-
-
Reverter, D.1
Lima, C.D.2
-
39
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
DOI 10.1016/S0076-6879(97)76066-X
-
Otwinowski Z, Minor W (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 276:307-326. (Pubitemid 27085611)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
40
-
-
37549039510
-
A short history of SHELX
-
Sheldrick GM (2008) A short history of SHELX. Acta Crystallogr A 64:112-122.
-
(2008)
Acta Crystallogr A
, vol.64
, pp. 112-122
-
-
Sheldrick, G.M.1
-
41
-
-
0032964481
-
Automated protein model building combined with iterative structure refinement
-
DOI 10.1038/8263
-
Perrakis A, Morris R, Lamzin VS (1999) Automated protein model building combined with iterative structure refinement. Nat Struct Biol 6:458-463. (Pubitemid 29218016)
-
(1999)
Nature Structural Biology
, vol.6
, Issue.5
, pp. 458-463
-
-
Perrakis, A.1
Morris, R.2
Lamzin, V.S.3
-
43
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC (2002) PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr D Biol Crystallogr 58:1948-1954.
-
(2002)
Acta Crystallogr D Biol Crystallogr
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
Read, R.J.7
Sacchettini, J.C.8
Sauter, N.K.9
Terwilliger, T.C.10
-
44
-
-
0027169515
-
Mainchain bond lengths and bond angles in protein structures
-
Laskowski RA, Moss DS, Thornton JM (1993) Mainchain bond lengths and bond angles in protein structures. J Mol Biol 231:1049-1067.
-
(1993)
J Mol Biol
, vol.231
, pp. 1049-1067
-
-
Laskowski, R.A.1
Moss, D.S.2
Thornton, J.M.3
-
45
-
-
0027180507
-
Verification of protein structures: Patterns of nonbonded atomic interactions
-
Colovos C, Yeates TO (1993) Verification of protein structures: patterns of nonbonded atomic interactions. Protein Sci 2:1511-1519. (Pubitemid 23262844)
-
(1993)
Protein Science
, vol.2
, Issue.9
, pp. 1511-1519
-
-
Colovos, C.1
Yeates, T.O.2
-
46
-
-
0026610767
-
Assessment of protein models with three-dimensional profiles
-
Luthy R, Bowie JU, Eisenberg D (1992) Assessment of protein models with three-dimensional profiles. Nature 356:83-85.
-
(1992)
Nature
, vol.356
, pp. 83-85
-
-
Luthy, R.1
Bowie, J.U.2
Eisenberg, D.3
-
47
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project N
-
Collaborative Computational Project N (1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 50:760-763.
-
(1994)
Acta Crystallogr D Biol Crystallogr
, vol.50
, pp. 760-763
-
-
-
48
-
-
0043237703
-
Potential for dramatic improvement in sequence alignment against structures of remote homologous proteins by extracting structural information from multiple structure alignment
-
DOI 10.1016/S0022-2836(03)00858-1
-
Zhang Z, Lindstam M, Unge J, Peterson C, Lu G (2003) Potential for dramatic improvement in sequence alignment against structures of remote homologous proteins by extracting structural information from multiple structure alignment. J Mol Biol 332:127-142. (Pubitemid 36999736)
-
(2003)
Journal of Molecular Biology
, vol.332
, Issue.1
, pp. 127-142
-
-
Zhang, Z.1
Lindstam, M.2
Unge, J.3
Peterson, C.4
Lu, G.5
|