Autoantibody against caspase-3, an executioner of apoptosis, in patients with systemic sclerosis

Rheumatology International

Volumn 30, Issue 7, 2010, Pages 871-878

  Okazaki, Shihoko ^a   Ogawa, Fumihide ^a   Iwata, Yohei ^a   Hara, Toshihide ^a   Muroi, Eiji ^a   Komura, Kazuhiro ^a   Takenaka, Motoi ^a   Shimizu, Kazuhiro ^a   Hasegawa, Minoru ^b   Fujimoto, Manabu ^b   Sato, Shinichi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Autoantibody; Caspase 3; Pulmonary fibrosis; Renal vascular damage; Systemic sclerosis

Indexed keywords

AUTOANTIBODY; CASPASE 3; IMMUNOGLOBULIN G;

ADULT; ANTIBODY DETECTION; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; DISEASE DURATION; DISEASE SEVERITY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; LUNG FIBROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SYSTEMIC SCLEROSIS;

ADULT; APOPTOSIS; AUTOANTIBODIES; BIOLOGICAL MARKERS; CASPASE 3; DINOPROST; FEMALE; HUMANS; IMMUNOGLOBULIN G; KIDNEY DISEASES; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PULMONARY FIBROSIS; RENAL CIRCULATION; SCLERODERMA, SYSTEMIC; VASCULITIS;

EID: 77955094748     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-009-1068-3     Document Type: Article

References (38)

1. Okano Y (1996) Antinuclear antibody in systemic sclerosis (scleroderma). Rheum Dis Clin North Am 22:709-735.
2. Ho KT, Reveille JD (2003) The clinical relevance of autoantibodies in scleroderma. Arthritis Res Ther 5:80-93.
3. Koenig M, Dieude M, Senecal JL (2008) Predictive value of antinuclear autoantibodies: the lessons of the systemic sclerosis autoantibodies. Autoimmun Rev 7:588-593.
4. Grassegger A, Pohla-Gubo G, Frauscher M, Hintner H (2008) Autoantibodies in systemic sclerosis (scleroderma): clues for clinical evaluation, prognosis and pathogenesis. Wien Med Wochenschr 158:19-28.
5. Iwata Y, Ogawa F, Komura K, Muroi E, Hara T, Shimizu K et al (2007) Autoantibody against peroxiredoxin I, an antioxidant enzyme, in patients with systemic sclerosis: possible association with oxidative stress. Rheumatology 46:790-795.
6. Nishijima C, Hayakawa I, Matsushita T, Komura K, Hasegawa M, Takehara K et al (2004) Autoantibody against matrix metalloproteinase- 3 in patients with systemic sclerosis. Clin Exp Immunol 138:357-363. (Pubitemid 39472456)
7. Sato S, Hayakawa I, Hasegawa M, Fujimoto M, Takehara K (2003) Function blocking autoantibodies against matrix metalloproteinase-1 in patients with systemic sclerosis. J Invest Dermatol 120:542-547.
8. Matucci Cerinic M, Kahaleh MB (2002) Beauty and the beast. The nitric oxide paradox in systemic sclerosis. Rheumatology 41:843-847.
9. Sgonc R, Gruschwitz MS, Boeck G, Sepp N, Gruber J, Wick G (2000) Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95. Arthritis Rheum 43:2550-2562.
10. Boatright KM, Salvesen GS (2003) Mechanisms of caspase activation. Curr Opin Cell Biol 15:725-731.
11. Nadiri A, Wolinski MK, Saleh M (2006) The inflammatory caspases: key players in the host response to pathogenic invasion and sepsis. J Immunol 177:4239-4245.
12. Fang B, Boross PI, Tozser J, Weber IT (2006) Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol 360:654-666.
13. Ni CZ, Li C, Wu JC, Spada AP, Ely KR (2003) Conformational restrictions in the active site of unliganded human caspase-3. J Mol Recognit 16:121-124.
14. Sisto M, Lisi S, Castellana D, Scagliusi P, D'Amore M, Caprio S et al (2006) Autoantibodies from Sjogren's syndrome induce activation of both the intrinsic and extrinsic apoptotic pathways in human salivary gland cell line A-253. J Autoimmun 27:38-49.
15. Yamamoto T, Nishioka K (2004) Possible role of apoptosis in the pathogenesis of bleomycin-induced scleroderma. J Invest Dermatol 122:44-50.
16. Elizabeth AS, Colon A, Seamus JM (2001) Executioner caspase- 3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis. J Biol Chem 276:7320-7326.
17. Sabbagh L, Kaech SM, Bourbonniere M, Woo M, Cohen LY, Haddad EK et al (2004) The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. J Immunol 173:5425-5433.
18. Xue C, Lan-Lan W, Bei C, Jie C, Wei-Hua F (2006) Abnormal Fas/FasL and caspase-3-mediated apoptotic signaling pathways of T lymphocyte subset in patients with systemic lupus erythematosus. Cell Immunol 239:121-128.
19. Cipriani P, Fulminis A, Pingiotti E, Marrelli A, Liakouli V, Perricone R et al (2006) Resistance to apoptosis in circulating alpha/beta and gamma/delta T lymphocytes from patients with systemic sclerosis. J Rheumatol 33:2003-2014.
20. Ueki A, Isozaki Y, Tomokuni A, Hatayama T, Ueki H, Kusaka M et al (2002) Intramolecular epitope spreading among anti-caspase- 8 autoantibodies in patients with silicosis, systemic sclerosis and systemic lupus erythematosus, as well as in healthy individuals. Clin Exp Immunol 129:556-561.
21. (1980) Preliminary criteria for the classiWcation of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 23:581-590.
22. LeRoy EC, Krieg T, Black C, Medsger TAJ, Fleischmajer R, Rowell N et al (1988) Scleroderma (systemic sclerosis): classification, subsets, and pathogenesis. J Rheumatol 15:202-205.
23. Clements PJ, Lachenbruch PA, Seibold JR, Zee B, Steen VD, Brennan P et al (1993) Skin thickness score in systemic sclerosis: an assessment of interobserver variability in 3 independent studies. J Rheumatol 20:1892-1896.
24. Sato S, Ihn H, Kikuchi K, Takehara K (1994) Antihistone antibodies in systemic sclerosis: association with pulmonary Wbrosis. Arthritis Rheum 37:391-394.
25. Nishijima C, Sato S, Hasegawa M, Nagaoka T, Hirata A, Komatsu K et al (2001) Renal vascular damage in Japanese patients with systemic sclerosis. Rheumatology 40:109-406.
26. Sato S, Hasegawa M, Fujimoto M, Tedder TF, Takehara K (2000) Quantitative genetic variation in CD19 expression correlates with autoimmunity. J Immunol 165:6635-6643.
27. Ogawa F, Shimizu K, Muroi E, Hara T, Hasegawa M, Takehara K et al (2006) Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis. Rheumatology 45:815-818. (Pubitemid 43985368)
28. Sato S, Ihn H, Soma Y, Igarashi A, Tamaki T, Kikuchi K et al (1993) Antihistone antibodies in patients with localized scleroderma. Arthritis Rheum 36:1137-1141.
29. Morrow JD, Roberts LJ 2nd (1996) The isoprostanes. Current knowledge and directions for future research. Biochem Pharmacol 51:1-9.
30. Sgonc R, Gruschwitz MS, Dietrich H, Recheis H, Gershwin ME, Wick G (1996) Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. J Clin Invest 98:785-792.
31. Casiano CA, Martin SJ, Green DR, Tan EM (1996) Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis. J Exp Med 184:765-770.
32. Panchenko MV, Farber HW, Korn JH (2000) Induction of heme oxygenase-1 by hypoxia and free radicals in human dermal Wbroblasts. Am J Physiol Cell Physiol 278:C92-C101.
33. Suematsu M, Wakabayashi Y, Ishimura Y (1996) Gaseous monoxides: a new class of microvascular regulator in the liver. Cardiovasc Res 32:679-686.
34. Butler AR, Flitney FW, Williams DL (1995) NO, nitrosonium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: a chemist's perspective. Trends Pharmacol Sci 16:18-22.
35. Dosreis GA, Borges VM, Zin WA (2004) The central role of Fas-ligand cell signaling in inflammatory lung diseases. J Cell Mol Med 8:285-293.
36. Hagimoto N, Kuwano K, Inoshima I, Yoshimi M, Nakamura N, Fujita M et al (2002) TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J Immunol 168:6470-6478. (Pubitemid 34620072)
37. Plataki M, Koutsopoulos AV, Darivianaki K, Delides G, Siafakas NM, Bouros D (2005) Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary Wbrosis. Chest 127:266-274.
38. Nagy G, Koncz A, Perl A (2005) T- and B-cell abnormalities in systemic lupus erythematosus. Crit Rev Immunol 25:123-140. (Pubitemid 40910585)