-
1
-
-
0033770667
-
Clinical trials of single-agent trastuzumab (Herceptin)
-
Baselga J. Clinical trials of single-agent trastuzumab (Herceptin). Semin. Oncol. 2000, 5(Suppl. 9):20-26.
-
(2000)
Semin. Oncol.
, vol.5
, Issue.SUPPL. 9
, pp. 20-26
-
-
Baselga, J.1
-
2
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
Baselga J., Tripathy D., Mendelsohn J., Baughman S., Benz C.C., Dantis L., Sklarin N.T., Seidman A.D., Hudis C.A., Moore J., Rosen P.P., Twaddell T., Henderson I.C., Norton L. Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J. Clin. Oncol. 1996, 14:737-744.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
3
-
-
73649130228
-
Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed
-
Bassett C.M., Rodriguez-Leyva D., Pierce G.N. Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed. Appl. Physiol. Nutr. Metab. 2009, 34:965-974.
-
(2009)
Appl. Physiol. Nutr. Metab.
, vol.34
, pp. 965-974
-
-
Bassett, C.M.1
Rodriguez-Leyva, D.2
Pierce, G.N.3
-
4
-
-
33847392879
-
Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
-
Bergman Jungestrom M., Thompson L.U., Dabrosin C. Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clin. Cancer Res. 2007, 13:1061-1067.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1061-1067
-
-
Bergman Jungestrom, M.1
Thompson, L.U.2
Dabrosin, C.3
-
5
-
-
34247133519
-
Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005
-
Boon H.S., Olatunde F., Zick S.M. Trends in complementary/alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Women's Health 2007, 7:4.
-
(2007)
BMC Women's Health
, vol.7
, pp. 4
-
-
Boon, H.S.1
Olatunde, F.2
Zick, S.M.3
-
7
-
-
0036966926
-
Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor
-
Chen J., Stavro P.M., Thompson L.U. Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor. Nutr. Cancer 2002, 43:187-192.
-
(2002)
Nutr. Cancer
, vol.43
, pp. 187-192
-
-
Chen, J.1
Stavro, P.M.2
Thompson, L.U.3
-
8
-
-
9344238812
-
Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (MCF-7) in nude mice
-
Chen J., Hui E., Ip T., Thompson L.U. Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (MCF-7) in nude mice. Clin. Cancer Res. 2004, 10:7703-7711.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 7703-7711
-
-
Chen, J.1
Hui, E.2
Ip, T.3
Thompson, L.U.4
-
9
-
-
34548252876
-
Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by down-regulating the expression of estrogen related gene products and signal transduction pathways
-
Chen J., Power K.A., Mann J., Cheng A., Thompson L.U. Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by down-regulating the expression of estrogen related gene products and signal transduction pathways. Nutr. Cancer 2007, 58:162-170.
-
(2007)
Nutr. Cancer
, vol.58
, pp. 162-170
-
-
Chen, J.1
Power, K.A.2
Mann, J.3
Cheng, A.4
Thompson, L.U.5
-
10
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh M., Vogel C., Tripathy D., Robert N., Scholl S., Fehrenbacher L., Wolter J., Paton V., Shak S., Lieberman G., Slamon D. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J. Clin. Oncol. 1999, 17:2639-2648.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.1
Vogel, C.2
Tripathy, D.3
Robert, N.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.7
Paton, V.8
Shak, S.9
Lieberman, G.10
Slamon, D.11
-
11
-
-
0022469463
-
Dietary fat and mammary cancer. II. Modulation of serum and tumor lipid composition and tumor prostaglandins by different dietary fats: association with tumor incidence patterns
-
Cohen L.A., Thompson D.O., Choi K., Karmali R.A., Rose D.P. Dietary fat and mammary cancer. II. Modulation of serum and tumor lipid composition and tumor prostaglandins by different dietary fats: association with tumor incidence patterns. J. Natl. Cancer Inst. 1986, 77:43-51.
-
(1986)
J. Natl. Cancer Inst.
, vol.77
, pp. 43-51
-
-
Cohen, L.A.1
Thompson, D.O.2
Choi, K.3
Karmali, R.A.4
Rose, D.P.5
-
12
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
Crone S.A., Zhao Y.Y., Fan L., Gu Y., Minamisawa S., Liu Y., Peterson K.L., Chen J., Kahn R., Condorelli G., Ross J., Chien K.R., Lee K.F. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat. Med. 2002, 8:459-465.
-
(2002)
Nat. Med.
, vol.8
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.Y.2
Fan, L.3
Gu, Y.4
Minamisawa, S.5
Liu, Y.6
Peterson, K.L.7
Chen, J.8
Kahn, R.9
Condorelli, G.10
Ross, J.11
Chien, K.R.12
Lee, K.F.13
-
13
-
-
70349935179
-
Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth
-
Ghosh-Choudhury T., Mandal C.C., Woodruff K., StClair P., Fernandes G., Choudhury G.G., Ghosh-Choudhury N. Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth. Breast Cancer Res. Treat. 2009, 118:213-228.
-
(2009)
Breast Cancer Res. Treat.
, vol.118
, pp. 213-228
-
-
Ghosh-Choudhury, T.1
Mandal, C.C.2
Woodruff, K.3
StClair, P.4
Fernandes, G.5
Choudhury, G.G.6
Ghosh-Choudhury, N.7
-
14
-
-
0037149539
-
Tumor biology: herceptin acts as an anti-angiogenic cocktail
-
Izumi Y., Xu L., di Tomaso E., Fukumura D., Jain R.K. Tumor biology: herceptin acts as an anti-angiogenic cocktail. Nature 2002, 416:279-280.
-
(2002)
Nature
, vol.416
, pp. 279-280
-
-
Izumi, Y.1
Xu, L.2
di Tomaso, E.3
Fukumura, D.4
Jain, R.K.5
-
15
-
-
0034002793
-
Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
-
Kuhajda F. Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 2008, 16:202-208.
-
(2008)
Nutrition
, vol.16
, pp. 202-208
-
-
Kuhajda, F.1
-
16
-
-
6944240423
-
N-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon
-
Ma D.W.L., Seo J., Davidson L.A., Callaway E.S., Fan Y.Y., Lupton J.R., Chapkin R.S. N-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon. FASEB J. 2004, 18:1040-1042.
-
(2004)
FASEB J.
, vol.18
, pp. 1040-1042
-
-
Ma, D.W.L.1
Seo, J.2
Davidson, L.A.3
Callaway, E.S.4
Fan, Y.Y.5
Lupton, J.R.6
Chapkin, R.S.7
-
17
-
-
11144348618
-
Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal α-linolenic acid and γ-linolenic acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis
-
Menendez J., Ropero S., Mehmi I., Atlas E., Colomer R., Lupu R. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal α-linolenic acid and γ-linolenic acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. Int. J. Oncol. 2004, 24:1369-1383.
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 1369-1383
-
-
Menendez, J.1
Ropero, S.2
Mehmi, I.3
Atlas, E.4
Colomer, R.5
Lupu, R.6
-
18
-
-
3242685815
-
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu(erbB2) oncogene overexpression in cancer cells
-
Menendez J., Vellon L., Mehmi I., Oza B.P., Roper S., Colomer R., Lupu R. Inhibition of fatty acid synthase (FAS) suppresses HER2/neu(erbB2) oncogene overexpression in cancer cells. PNAS 2004, 101:10715-10720.
-
(2004)
PNAS
, vol.101
, pp. 10715-10720
-
-
Menendez, J.1
Vellon, L.2
Mehmi, I.3
Oza, B.P.4
Roper, S.5
Colomer, R.6
Lupu, R.7
-
19
-
-
34249876936
-
HER2 (erbB-2)-targeted effects of the ω-3 polyunsaturated. Fatty acid α-linolenic acid (ALA:18:3n-3) in breast cancer cells: the " fat features" of the " Mediterranean diet" as an " anti-HER2 cocktail"
-
Menendez J., Vazquez-Martin A., Ropero S., Colomer R., Lupu R. HER2 (erbB-2)-targeted effects of the ω-3 polyunsaturated. Fatty acid α-linolenic acid (ALA:18:3n-3) in breast cancer cells: the " fat features" of the " Mediterranean diet" as an " anti-HER2 cocktail" Clin. Transl. Oncol. 2006, 8:812-820.
-
(2006)
Clin. Transl. Oncol.
, vol.8
, pp. 812-820
-
-
Menendez, J.1
Vazquez-Martin, A.2
Ropero, S.3
Colomer, R.4
Lupu, R.5
-
20
-
-
0029039990
-
The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers - a review
-
Ravdin P.M., Chamness G.C. The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers - a review. Gene 1995, 159:19-27.
-
(1995)
Gene
, vol.159
, pp. 19-27
-
-
Ravdin, P.M.1
Chamness, G.C.2
-
21
-
-
0027487229
-
AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
-
Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993, 123:1939-1951.
-
(1993)
J. Nutr.
, vol.123
, pp. 1939-1951
-
-
Reeves, P.G.1
Nielsen, F.H.2
Fahey, G.C.3
-
22
-
-
77649281088
-
Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen receptor- and growth factor-signaling pathways
-
Saggar J., Chen J., Corey P., Thompson L.U. Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen receptor- and growth factor-signaling pathways. Mol. Nutr. Food Res. 2010, 54:415-425.
-
(2010)
Mol. Nutr. Food Res.
, vol.54
, pp. 415-425
-
-
Saggar, J.1
Chen, J.2
Corey, P.3
Thompson, L.U.4
-
23
-
-
33947169954
-
(n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells
-
Schley P., Brindley D., Field C.J. (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells. J. Nutr. 2007, 137:548-553.
-
(2007)
J. Nutr.
, vol.137
, pp. 548-553
-
-
Schley, P.1
Brindley, D.2
Field, C.J.3
-
24
-
-
0026699914
-
Effect of low level flaxseed supplementation on the fatty acid composition of mammary glands and tumors in rats
-
Serraino M.R., Thompson L.U., Cunnane S.C. Effect of low level flaxseed supplementation on the fatty acid composition of mammary glands and tumors in rats. Nutr. Res. 1992, 12:767-772.
-
(1992)
Nutr. Res.
, vol.12
, pp. 767-772
-
-
Serraino, M.R.1
Thompson, L.U.2
Cunnane, S.C.3
-
25
-
-
0029902997
-
Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis
-
Thompson L.U., Rickard S.E., Orcheson L.J., Seidl M. Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 1996, 17:1373-1376.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1373-1376
-
-
Thompson, L.U.1
Rickard, S.E.2
Orcheson, L.J.3
Seidl, M.4
-
26
-
-
18844389202
-
Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer
-
Thompson L.U., Chen J., Li T., Strasser-Weippl K., Goss P.E. Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clin. Cancer Res. 2005, 11:3828-3835.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3828-3835
-
-
Thompson, L.U.1
Chen, J.2
Li, T.3
Strasser-Weippl, K.4
Goss, P.E.5
-
27
-
-
77955052781
-
Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen
-
(Epub ahead of print)
-
Truan, J., Chen, J.M., Thompson, L.U., 2010. Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen. Mol. Nutr. Food Res. (Epub ahead of print).
-
(2010)
Mol. Nutr. Food Res.
-
-
Truan, J.1
Chen, J.M.2
Thompson, L.U.3
-
28
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I., Sawyers C.L. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2002, 2:489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
29
-
-
0036467826
-
Efficacy and safety of Trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel C.L., Cobleigh M.A., Tripathy D., Gutheil J.C., Harris L.N., Fehrenbacher L., Slamon D.J., Murphy M., Novotny W.F., Burchmore M., Shak S., Stewart S.J., Press M. Efficacy and safety of Trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 2002, 20:719-726.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
30
-
-
23244462764
-
The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components
-
Wang L., Chen J., Thompson L.U. The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Int. J. Cancer 2005, 116:793-797.
-
(2005)
Int. J. Cancer
, vol.116
, pp. 793-797
-
-
Wang, L.1
Chen, J.2
Thompson, L.U.3
|