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Volumn 58, Issue 2, 2007, Pages 162-170

Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN; ESTROGEN RECEPTOR; GENE PRODUCT; SOMATOMEDIN C RECEPTOR; TAMOXIFEN;

EID: 34548252876     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635580701328271     Document Type: Article
Times cited : (26)

References (54)
  • 1
    • 0038761469 scopus 로고    scopus 로고
    • Flaxseed, lignans, and cancer
    • 2nd ed, Thompson LU and Cunnane SC eds, Champaign, IL: AOCS Press
    • Thompson LU: Flaxseed, lignans, and cancer. In Flaxseed in Human Nutrition (2nd ed.), Thompson LU and Cunnane SC (eds.). Champaign, IL: AOCS Press, 2003, pp. 194-222.
    • (2003) Flaxseed in Human Nutrition , pp. 194-222
    • Thompson, L.U.1
  • 3
    • 9344258823 scopus 로고    scopus 로고
    • α-Linolenic acid and cancer
    • 2nd ed, Thompson LU and Cunnane SC eds, Champaign, IL: AOCS Press
    • Bougnoux P and Chajes V: α-Linolenic acid and cancer. In Flaxseed in Human Nutrition (2nd ed.), Thompson LU and Cunnane SC (eds.). Champaign, IL: AOCS Press, 2003, pp. 232-244.
    • (2003) Flaxseed in Human Nutrition , pp. 232-244
    • Bougnoux, P.1    Chajes, V.2
  • 4
    • 0025940535 scopus 로고
    • The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis
    • Serraino M and Thompson LU: The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett 60, 135-142, 1991.
    • (1991) Cancer Lett , vol.60 , pp. 135-142
    • Serraino, M.1    Thompson, L.U.2
  • 5
    • 0029902997 scopus 로고    scopus 로고
    • Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis
    • Thompson LU, Rickard SE, Orcheson LJ, and Seidl MM: Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 17, 1373-1376, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 1373-1376
    • Thompson, L.U.1    Rickard, S.E.2    Orcheson, L.J.3    Seidl, M.M.4
  • 6
    • 0032806446 scopus 로고    scopus 로고
    • Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats
    • Rickard SE, Yuan YV, Chen J, and Thompson LU: Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Nutr Cancer 35, 50-57, 1999.
    • (1999) Nutr Cancer , vol.35 , pp. 50-57
    • Rickard, S.E.1    Yuan, Y.V.2    Chen, J.3    Thompson, L.U.4
  • 7
    • 0036966926 scopus 로고    scopus 로고
    • Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor
    • Chen J, Stavro PM, and Thompson LU: Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor. Nutr Cancer 43, 187-192, 2002.
    • (2002) Nutr Cancer , vol.43 , pp. 187-192
    • Chen, J.1    Stavro, P.M.2    Thompson, L.U.3
  • 8
    • 0037044563 scopus 로고    scopus 로고
    • Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts
    • Dabrosin C, Chen J, Wang L, and Thompson LU: Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts. Cancer Lett 185, 31-37, 2002.
    • (2002) Cancer Lett , vol.185 , pp. 31-37
    • Dabrosin, C.1    Chen, J.2    Wang, L.3    Thompson, L.U.4
  • 9
    • 33645009635 scopus 로고    scopus 로고
    • Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice
    • Chen J, Wang L, and Thompson LU: Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice. Cancer Lett 234, 168-175, 2006.
    • (2006) Cancer Lett , vol.234 , pp. 168-175
    • Chen, J.1    Wang, L.2    Thompson, L.U.3
  • 10
    • 23244462764 scopus 로고    scopus 로고
    • The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components
    • Wang L, Chen J, and Thompson LU: The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Int J Cancer 116, 793-798, 2005.
    • (2005) Int J Cancer , vol.116 , pp. 793-798
    • Wang, L.1    Chen, J.2    Thompson, L.U.3
  • 11
    • 18844389202 scopus 로고    scopus 로고
    • Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer
    • Thompson LU, Chen JM, Li T, Strasser-Weippl K, and Goss PE: Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clin Cancer Res 11, 3828-3835, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 3828-3835
    • Thompson, L.U.1    Chen, J.M.2    Li, T.3    Strasser-Weippl, K.4    Goss, P.E.5
  • 12
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr BJ and Jordan VC: The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 25, 127-205, 1984.
    • (1984) Pharmacol Ther , vol.25 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 13
    • 0035687170 scopus 로고    scopus 로고
    • The past, present, and future of selective estrogen receptor modulation
    • Jordan VC: The past, present, and future of selective estrogen receptor modulation. Ann N Y Acad Sci 949, 72-79, 2001.
    • (2001) Ann N Y Acad Sci , vol.949 , pp. 72-79
    • Jordan, V.C.1
  • 14
    • 0031778177 scopus 로고    scopus 로고
    • Basic guide to the mechanisms of antiestrogen action
    • MacGregor JI and Jordan VC: Basic guide to the mechanisms of antiestrogen action. Pharmacol Rev 50, 151-196, 1998.
    • (1998) Pharmacol Rev , vol.50 , pp. 151-196
    • MacGregor, J.I.1    Jordan, V.C.2
  • 15
    • 0142124242 scopus 로고    scopus 로고
    • Phytoestrogens: Potential benefits and implications for breast cancer survivors
    • Duffy C and Cyr M: Phytoestrogens: potential benefits and implications for breast cancer survivors. J Womens Health 12, 617-631, 2003.
    • (2003) J Womens Health , vol.12 , pp. 617-631
    • Duffy, C.1    Cyr, M.2
  • 16
    • 9344238812 scopus 로고    scopus 로고
    • Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice
    • Chen J, Hui E, Ip T, and Thompson LU: Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice. Clin Cancer Res 10, 7703-7711, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 7703-7711
    • Chen, J.1    Hui, E.2    Ip, T.3    Thompson, L.U.4
  • 17
    • 0030161996 scopus 로고    scopus 로고
    • Long-term tamoxifen therapy: Can an antagonist become an agonist?
    • Santen RJ: Long-term tamoxifen therapy: can an antagonist become an agonist? J Clin Endocrinol Metab 81, 2027-2029, 1996.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2027-2029
    • Santen, R.J.1
  • 18
    • 11244296162 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance
    • Ring A and Dowsett M: Mechanisms of tamoxifen resistance. Endocr Relat Cancer 11, 643-658, 2004.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 643-658
    • Ring, A.1    Dowsett, M.2
  • 19
    • 85039224191 scopus 로고
    • Olfer ED, Cross BM, and Mc William AA eds, 2nd ed, Ottawa, Ontario, Canada: Canadian Council on Animal Care
    • Olfer ED, Cross BM, and Mc William AA (eds.): The Guide to the Care and Use of Experimental Animals (Vol. 1, 2nd ed.). Ottawa, Ontario, Canada: Canadian Council on Animal Care, 1993.
    • (1993) The Guide to the Care and Use of Experimental Animals , vol.1
  • 20
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, and Fahey Jr. GC: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951, 1993.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 21
    • 0036569703 scopus 로고    scopus 로고
    • Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice
    • Ju YH, Doerge DR, Allred KF, Allred CD, and Helferich WG: Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. Cancer Res 62, 2474-2477, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2474-2477
    • Ju, Y.H.1    Doerge, D.R.2    Allred, K.F.3    Allred, C.D.4    Helferich, W.G.5
  • 22
    • 0031915998 scopus 로고    scopus 로고
    • Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    • Allred DC, Harvey JM, Berardo M, and Clark GM: Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 11, 155-168, 1998.
    • (1998) Mod Pathol , vol.11 , pp. 155-168
    • Allred, D.C.1    Harvey, J.M.2    Berardo, M.3    Clark, G.M.4
  • 23
    • 3242798960 scopus 로고    scopus 로고
    • Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ER α) and ER β in human cells
    • Mueller SO, Simon S, Chae K, Metzler M, and Korach KS: Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ER α) and ER β in human cells. Toxicol Sci 80, 14-25, 2004.
    • (2004) Toxicol Sci , vol.80 , pp. 14-25
    • Mueller, S.O.1    Simon, S.2    Chae, K.3    Metzler, M.4    Korach, K.S.5
  • 24
    • 9344235716 scopus 로고    scopus 로고
    • Mechanism of anticancer effects of lignans with a special emphasis on breast cancer
    • 2nd ed, Thompson LU and Cunnane SC eds, Champaign, IL: AOCS Press
    • Saarinen N, Makela S, and Santti R: Mechanism of anticancer effects of lignans with a special emphasis on breast cancer. In Flaxseed in Human Nutrition (2nd ed.), Thompson LU and Cunnane SC (eds.). Champaign, IL: AOCS Press, 2003, pp 223-231.
    • (2003) Flaxseed in Human Nutrition , pp. 223-231
    • Saarinen, N.1    Makela, S.2    Santti, R.3
  • 25
    • 0028972676 scopus 로고
    • Inhibition of 5 α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids
    • Evans B, Griffiths K, and Morton M: Inhibition of 5 α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids. J Endocrinol 147, 295-302, 1995.
    • (1995) J Endocrinol , vol.147 , pp. 295-302
    • Evans, B.1    Griffiths, K.2    Morton, M.3
  • 26
    • 18144386167 scopus 로고    scopus 로고
    • Mammalian lignans and genistein decrease the activity of aromatase and 17β-hydroxysteroid dehydrogenase in MCF-7 cells
    • Brooks JD and Thompson LU: Mammalian lignans and genistein decrease the activity of aromatase and 17β-hydroxysteroid dehydrogenase in MCF-7 cells. J Steroid Biochem Mol Biol 94, 461-467, 2005.
    • (2005) J Steroid Biochem Mol Biol , vol.94 , pp. 461-467
    • Brooks, J.D.1    Thompson, L.U.2
  • 27
    • 0036690593 scopus 로고    scopus 로고
    • Enterolactone inhibits the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in the rat
    • Saarinen NM, Huovinen R, Warri A, Makela SI, Valentin-Blasini L, et al.: Enterolactone inhibits the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in the rat. Mol Cancer Ther 1, 869-876, 2002.
    • (2002) Mol Cancer Ther , vol.1 , pp. 869-876
    • Saarinen, N.M.1    Huovinen, R.2    Warri, A.3    Makela, S.I.4    Valentin-Blasini, L.5
  • 28
    • 2342499956 scopus 로고    scopus 로고
    • Phyto-oestrogens and breast cancer chemoprevention
    • Limer JL and Speirs V: Phyto-oestrogens and breast cancer chemoprevention. Breast Cancer Res 6, 119-127, 2004.
    • (2004) Breast Cancer Res , vol.6 , pp. 119-127
    • Limer, J.L.1    Speirs, V.2
  • 29
    • 0030880014 scopus 로고    scopus 로고
    • Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells
    • Wang C and Kurzer MS: Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells. Nutr Cancer 28, 236-247, 1997.
    • (1997) Nutr Cancer , vol.28 , pp. 236-247
    • Wang, C.1    Kurzer, M.S.2
  • 30
    • 33745911131 scopus 로고    scopus 로고
    • Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with mcf-7 human breast cancer xenografts
    • Saarinen NM, Power KA, Chen J, and Thompson LU: Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with mcf-7 human breast cancer xenografts. Intl J Cancer 119, 925-931, 2006.
    • (2006) Intl J Cancer , vol.119 , pp. 925-931
    • Saarinen, N.M.1    Power, K.A.2    Chen, J.3    Thompson, L.U.4
  • 31
    • 31844438592 scopus 로고    scopus 로고
    • Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice
    • Power KA, Saarinen NM, Chen JM, and Thompson LU: Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF-7 xenografts in ovariectomized athymic nude mice. Int J Cancer 118, 1316-1320, 2006.
    • (2006) Int J Cancer , vol.118 , pp. 1316-1320
    • Power, K.A.1    Saarinen, N.M.2    Chen, J.M.3    Thompson, L.U.4
  • 32
    • 0030692082 scopus 로고    scopus 로고
    • Effects of dietary fatty acids on breast and prostate cancers: Evidence from in vitro experiments and animal studies
    • Rose DP: Effects of dietary fatty acids on breast and prostate cancers: evidence from in vitro experiments and animal studies. Am J Clin Nutr 66, 1513S-1522S, 1997.
    • (1997) Am J Clin Nutr , vol.66
    • Rose, D.P.1
  • 33
    • 0036212979 scopus 로고    scopus 로고
    • n-3 fatty acids and lipid peroxidation in breast cancer inhibition
    • Stoll BA: n-3 fatty acids and lipid peroxidation in breast cancer inhibition. Br J Nutr 87, 193-198, 2002.
    • (2002) Br J Nutr , vol.87 , pp. 193-198
    • Stoll, B.A.1
  • 34
    • 0030762252 scopus 로고    scopus 로고
    • Dietary fatty acids and prevention of hormone-responsive cancer
    • Rose DP: Dietary fatty acids and prevention of hormone-responsive cancer. Proc Soc Exp Biol Med 216, 224-233, 1997.
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 224-233
    • Rose, D.P.1
  • 35
    • 0030865838 scopus 로고    scopus 로고
    • Regulation of mevalonate synthesis in rat mammary glands by dietary n-3 and n-6 polyunsaturated fatty acids
    • El-Sohemy A and Archer MC: Regulation of mevalonate synthesis in rat mammary glands by dietary n-3 and n-6 polyunsaturated fatty acids. Cancer Res 57, 3685-3687, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3685-3687
    • El-Sohemy, A.1    Archer, M.C.2
  • 36
    • 0041853713 scopus 로고    scopus 로고
    • Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity
    • DeGraffenried LA, Friedrichs WE, Fulcher L, Fernandes G, Silva JM, et al.: Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity. Ann Oncol 14, 1051-1056, 2003.
    • (2003) Ann Oncol , vol.14 , pp. 1051-1056
    • DeGraffenried, L.A.1    Friedrichs, W.E.2    Fulcher, L.3    Fernandes, G.4    Silva, J.M.5
  • 37
    • 0031123463 scopus 로고    scopus 로고
    • Aromatase expression and its localization in human breast cancer
    • Sasano H and Ozaki M: Aromatase expression and its localization in human breast cancer. J Steroid Biochem Mol Biol 61, 293-298, 1997.
    • (1997) J Steroid Biochem Mol Biol , vol.61 , pp. 293-298
    • Sasano, H.1    Ozaki, M.2
  • 38
    • 0030745396 scopus 로고    scopus 로고
    • Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4
    • Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, et al.: Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol 17, 5338-5347, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 5338-5347
    • Neuman, E.1    Ladha, M.H.2    Lin, N.3    Upton, T.M.4    Miller, S.J.5
  • 39
    • 0037089564 scopus 로고    scopus 로고
    • Rate-limiting effects of cyclin D1 in transformation by ErbB2 predicts synergy between herceptin and flavopiridol
    • Nahta R, Iglehart JD, Kempkes B, and Schmidt EV: Rate-limiting effects of cyclin D1 in transformation by ErbB2 predicts synergy between herceptin and flavopiridol. Cancer Res 62, 2267-2271, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2267-2271
    • Nahta, R.1    Iglehart, J.D.2    Kempkes, B.3    Schmidt, E.V.4
  • 40
    • 0037025323 scopus 로고    scopus 로고
    • Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression
    • Liu MM, Albanese C, Anderson CM, Hilty K, Webb P, et al.: Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression. J Biol Chem 277, 24353-24360, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 24353-24360
    • Liu, M.M.1    Albanese, C.2    Anderson, C.M.3    Hilty, K.4    Webb, P.5
  • 41
    • 1242300083 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D
    • Strom A, Hartman J, Foster JS, Kietz S, Wimalasena J, et al.: Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc Natl Acad Sci USA 101, 1566-1571, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1566-1571
    • Strom, A.1    Hartman, J.2    Foster, J.S.3    Kietz, S.4    Wimalasena, J.5
  • 42
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice
    • Lindberg MK, Moverare S, Skrtic S, Gao H, Dahlman-Wright K, et al.: Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol Endocrinol 17, 203-208, 2003.
    • (2003) Mol Endocrinol , vol.17 , pp. 203-208
    • Lindberg, M.K.1    Moverare, S.2    Skrtic, S.3    Gao, H.4    Dahlman-Wright, K.5
  • 43
    • 0034624313 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside
    • Rickard SE, Yuan YV, and Thompson LU: Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside. Cancer Lett 161, 47-55, 2000.
    • (2000) Cancer Lett , vol.161 , pp. 47-55
    • Rickard, S.E.1    Yuan, Y.V.2    Thompson, L.U.3
  • 44
    • 11244296162 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance
    • Ring A and Dowsett M: Mechanisms of tamoxifen resistance. Endocr Relat Cancer 11, 643-658, 2004.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 643-658
    • Ring, A.1    Dowsett, M.2
  • 45
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: Increased estrogen receplor-HER2/neu cross-talk in ER/HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, AH S, et al.: Mechanisms of tamoxifen resistance: increased estrogen receplor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96, 926-935, 2004.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    AH, S.5
  • 46
    • 0033973395 scopus 로고    scopus 로고
    • Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer
    • Nicholson R I and Gee J M: Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer. Br J Cancer 82, 501-513, 2000.
    • (2000) Br J Cancer , vol.82 , pp. 501-513
    • Nicholson, R.I.1    Gee, J.M.2
  • 47
    • 0037420192 scopus 로고    scopus 로고
    • Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer
    • Osborne CK, Bardou V, Hopp TA, Chamness GC, Hilsenbeck SG, et al.: Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J Natl Cancer Inst 95, 353-361, 2003.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 353-361
    • Osborne, C.K.1    Bardou, V.2    Hopp, T.A.3    Chamness, G.C.4    Hilsenbeck, S.G.5
  • 48
    • 25844468319 scopus 로고    scopus 로고
    • Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer
    • Gee JM, Robertson JF, Gutteridge E, Ellis IO, Pinder SE, et al.: Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr Relat Cancer 12, S99-S111, 2005.
    • (2005) Endocr Relat Cancer , vol.12
    • Gee, J.M.1    Robertson, J.F.2    Gutteridge, E.3    Ellis, I.O.4    Pinder, S.E.5
  • 49
    • 18044379750 scopus 로고    scopus 로고
    • Growth factor signalling networks in breast cancer and resistance to endocrine agents: New therapeutic strategies
    • Nicholson RI, Hutcheson IR, Britton D, Knowlden JM, Giles M, et al.: Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies. J Steroid Biochem Mol Biol 93, 257-262, 2005.
    • (2005) J Steroid Biochem Mol Biol , vol.93 , pp. 257-262
    • Nicholson, R.I.1    Hutcheson, I.R.2    Britton, D.3    Knowlden, J.M.4    Giles, M.5
  • 50
    • 0037937417 scopus 로고    scopus 로고
    • Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells
    • Hamelers IH and Steenbergh PH: Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells. Endocr Relat Cancer 10, 331-345, 2003.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 331-345
    • Hamelers, I.H.1    Steenbergh, P.H.2
  • 51
    • 0019813814 scopus 로고
    • Determination of tamoxifen and biologically active metabolites in human breast tumours and plasma
    • Daniel P, Gaskell SJ, Bishop H, Campbell C, and Nicholson RI: Determination of tamoxifen and biologically active metabolites in human breast tumours and plasma. Eur J Cancer Clin Oncol 17, 1183-1189, 1981.
    • (1981) Eur J Cancer Clin Oncol , vol.17 , pp. 1183-1189
    • Daniel, P.1    Gaskell, S.J.2    Bishop, H.3    Campbell, C.4    Nicholson, R.I.5
  • 52
    • 11144355178 scopus 로고    scopus 로고
    • Tamoxifen and metabolite concentrations in scrum and breast cancer tissue during three dose regimens in a randomized preoperative trial
    • Kisanga ER, Gjerde J, Guerrieri-Gonzaga A, Pigatto F, Pesci-Feltri A, et al.: Tamoxifen and metabolite concentrations in scrum and breast cancer tissue during three dose regimens in a randomized preoperative trial. Clin Cancer Res 10, 2336-2343, 2004.
    • (2004) Clin Cancer Res , vol.10 , pp. 2336-2343
    • Kisanga, E.R.1    Gjerde, J.2    Guerrieri-Gonzaga, A.3    Pigatto, F.4    Pesci-Feltri, A.5
  • 54
    • 0026064491 scopus 로고
    • Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient
    • Robinson SP, Langan-Fahey SM, Johnson DA, and Jordan VC: Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient. Drug Metab Dispos 19, 36-43, 1991.
    • (1991) Drug Metab Dispos , vol.19 , pp. 36-43
    • Robinson, S.P.1    Langan-Fahey, S.M.2    Johnson, D.A.3    Jordan, V.C.4


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