Inhibitory effects of Bulnesia sarmienti aqueous extract on agonist-induced platelet activation and thrombus formation involves mitogen-activated protein kinases

Journal of Ethnopharmacology

Volumn 130, Issue 3, 2010, Pages 614-620

  Kamruzzaman, S M ^a   Endale, Mehari ^a   Oh, Won Jun ^a   Park, Seung Chun ^a   Kim, Kil Soo ^a   Hong, Joo Heon ^b   Kwak, Yi Seong ^c   Yun, Bong Sik ^d   Rhee, Man Hee ^a  

^a Kyungpook National University   (South Korea)

^b Catholic University of Daegu   (South Korea)

^c Korea Ginseng Corporation   (South Korea)

^d Chonbuk National University   (South Korea)

Author keywords

B. sarmienti extract; Catechins; MAP kinases; Platelet; Thrombus

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BULNESIA SARMIENTI EXTRACT; CATECHIN; COLLAGEN; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; PYROXYLIN; STRESS ACTIVATED PROTEIN KINASE 1; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTERIOVENOUS SHUNT; ARTICLE; BLEEDING TIME; BULNESIA SARMIENTI; CALCIUM MOBILIZATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; RAT; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOGENESIS; ANIMAL; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; IC50; METABOLISM; PHOSPHORYLATION; PROCEDURES; SPRAGUE DAWLEY RAT; THROMBOSIS; TRADITIONAL MEDICINE; ZYGOPHYLLACEAE;

ANIMALS; BLEEDING TIME; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; INHIBITORY CONCENTRATION 50; MALE; MEDICINE, TRADITIONAL; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLANT EXTRACTS; PLATELET ACTIVATION; PLATELET AGGREGATION; RATS; RATS, SPRAGUE-DAWLEY; THROMBOSIS; ZYGOPHYLLACEAE;

BULNESIA SARMIENTI; MUS; RATTUS;

EID: 77954958115     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.049     Document Type: Article

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