-
1
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk W. D, Wang S. S, Weinrich S. L, Avilion A. A, Chiu C. P, Adams R. R, Chang E, Allsopp R. C, Yu J, Le S, West M. D; Harley C. B, Andrews W. H, Greider C. W, Villeponteau B. The RNA component of human telomerase. Science. 1995; 269: 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.S.3
Weinrich, S.L.4
Avilion, A.A.5
Chiu, C.P.6
Adams, R.R.7
Chang, E.8
Allsopp, R.C.9
Yu, J.10
Le, S.11
West, M.D.12
Harley, C.B.13
Andrews, W.H.14
Greider, C.W.15
Villeponteau, B.16
-
2
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura T. M, Morin G. B, Chapman K. B, Weinrich S. L, Andrews W. H, Lingner J, Harley C. B, Cech T. R. Telomerase catalytic subunit homologs from fission yeast and human. Science. 1997; 277: 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
3
-
-
0031036350
-
A mammalian telomerase-associated protein
-
Harrington L, McPhail T, Mar V, Zhou W, Oulton R, Bass M. B, Arruda I, Robinson M. O. A mammalian telomerase-associated protein. Science. 1997; 275: 973-977.
-
(1997)
Science
, vol.275
, pp. 973-977
-
-
Harrington, L.1
McPhail, T.2
Mar, V.3
Zhou, W.4
Oulton, R.5
Bass, M.B.6
Arruda, I.7
Robinson, M.O.8
-
4
-
-
0032485416
-
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
-
Counter C. M, Meyerson M, Eaton E. N, Ellisen L. W, Caddle S. D, Haber D. A, Weinberg R. A. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 1998; 16: 1217-1222.
-
(1998)
Oncogene
, vol.16
, pp. 1217-1222
-
-
Counter, C.M.1
Meyerson, M.2
Eaton, E.N.3
Ellisen, L.W.4
Caddle, S.D.5
Haber, D.A.6
Weinberg, R.A.7
-
5
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
-
Meyerson M, Counter C. M, Eaton E. N, Ellisen L. W, Steiner P, Caddle S. D, Ziaugra L, Beijersbergen R. L, Davidoff M. J, Liu Q, Bacchetti S, Haber D. A, Weinberg R. A. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 1997; 90: 785-795.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
Counter, C.M.2
Eaton, E.N.3
Ellisen, L.W.4
Steiner, P.5
Caddle, S.D.6
Ziaugra, L.7
Beijersbergen, R.L.8
Davidoff, M.J.9
Liu, Q.10
Bacchetti, S.11
Haber, D.A.12
Weinberg, R.A.13
-
6
-
-
0035897568
-
Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)
-
Poole J. C, Andrews L. G, Tollefsbol T. O. Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT). Gene. 2001; 269: 1-12.
-
(2001)
Gene
, vol.269
, pp. 1-12
-
-
Poole, J.C.1
Andrews, L.G.2
Tollefsbol, T.O.3
-
7
-
-
0343415646
-
Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay
-
Bièche I, Noguès C, Paradis V, Olivi M, Bedossa P, Lidereau R, Vidaud M. Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay. Clin Cancer Res. 2000; 6: 452-459.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 452-459
-
-
Bièche, I.1
Noguès, C.2
Paradis, V.3
Olivi, M.4
Bedossa, P.5
Lidereau, R.6
Vidaud, M.7
-
8
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay J. W, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer. 1997; 33: 787-791.
-
(1997)
Eur J Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
9
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim N. W, Piatyszek M. A, Prowse K. R, Harley C. B, West M. D, Ho P. L, Coviello G. M, Wright W. E, Weinrich S. L, Shay J. W. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994; 266: 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
10
-
-
27744529808
-
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis
-
Quante M, Heeg S, Werder A, Goessel G, Fulda C, Doebele M, Nakagawa H, Beijersbergen R, Blum H. E, Opitz O. G. Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis. Carcinogenesis. 2005; 26: 1879-1889.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1879-1889
-
-
Quante, M.1
Heeg, S.2
Werder, A.3
Goessel, G.4
Fulda, C.5
Doebele, M.6
Nakagawa, H.7
Beijersbergen, R.8
Blum, H.E.9
Opitz, O.G.10
-
11
-
-
0034832792
-
Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions. to gain an insight into the biology of telomerase
-
Yang S. M, Fang D. C, Luo Y. H, Lu R, Battle P. D, Liu W. W. Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions. to gain an insight into the biology of telomerase. J Gastroenterol Hepatol. 2001; 16: 876-882.
-
(2001)
J Gastroenterol Hepatol
, vol.16
, pp. 876-882
-
-
Yang, S.M.1
Fang, D.C.2
Luo, Y.H.3
Lu, R.4
Battle, P.D.5
Liu, W.W.6
-
12
-
-
0033371752
-
Detection of telomerase activity in biopsy samples of colorectal cancer
-
Fang D. C, Young J, Luo Y. H, Lu R, Jass J. Detection of telomerase activity in biopsy samples of colorectal cancer. J Gastroenterol Hepatol. 1999; 14: 328-332.
-
(1999)
J Gastroenterol Hepatol
, vol.14
, pp. 328-332
-
-
Fang, D.C.1
Young, J.2
Luo, Y.H.3
Lu, R.4
Jass, J.5
-
13
-
-
42249104693
-
Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro
-
Yang S. M, Fang D. C, Yang J. L, Chen L, Luo Y. H, Liang G. P. Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro. Eur J Cancer Prev. 2008; 17: 209-217.
-
(2008)
Eur J Cancer Prev
, vol.17
, pp. 209-217
-
-
Yang, S.M.1
Fang, D.C.2
Yang, J.L.3
Chen, L.4
Luo, Y.H.5
Liang, G.P.6
-
15
-
-
0037148401
-
Regulation of the human telomerase reverse transcriptase gene
-
Ducrest A. L, Szutorisz H, Lingner J, Nabholz M. Regulation of the human telomerase reverse transcriptase gene. Oncogene. 2002; 21: 541-552.
-
(2002)
Oncogene
, vol.21
, pp. 541-552
-
-
Ducrest, A.L.1
Szutorisz, H.2
Lingner, J.3
Nabholz, M.4
-
16
-
-
0034048726
-
Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription
-
Kanaya T, Kyo S, Hamada K, Takakura M, Kitagawa Y, Harada H, Inoue M. Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription. Clin Cancer Res. 2000; 6: 1239-1247.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1239-1247
-
-
Kanaya, T.1
Kyo, S.2
Hamada, K.3
Takakura, M.4
Kitagawa, Y.5
Harada, H.6
Inoue, M.7
-
17
-
-
0343673898
-
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
-
Günes C, Lichtsteiner S, Vasserot A. P, Englert C. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res. 2000; 60: 2116-2121.
-
(2000)
Cancer Res
, vol.60
, pp. 2116-2121
-
-
Günes, C.1
Lichtsteiner, S.2
Vasserot, A.P.3
Englert, C.4
-
18
-
-
0035798379
-
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
-
Zhou X. Z, Lu K. P. The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. Cell. 2001; 107: 347-359.
-
(2001)
Cell
, vol.107
, pp. 347-359
-
-
Zhou, X.Z.1
Lu, K.P.2
-
19
-
-
58249097056
-
Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells
-
Zhang B, Bai Y. X, Ma H. H, Feng F, Jin R, Wang Z. L, Lin J, Sun S. P, Yang P, Wang X. X, Huang P. T, Huang C. F, Peng Y, Chen Y. C, Kung H. F, Huang J. J. Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells. Cancer Res. 2009; 69: 75-83.
-
(2009)
Cancer Res
, vol.69
, pp. 75-83
-
-
Zhang, B.1
Bai, Y.X.2
Ma, H.H.3
Feng, F.4
Jin, R.5
Wang, Z.L.6
Lin, J.7
Sun, S.P.8
Yang, P.9
Wang, X.X.10
Huang, P.T.11
Huang, C.F.12
Peng, Y.13
Chen, Y.C.14
Kung, H.F.15
Huang, J.J.16
-
20
-
-
12444313020
-
Loss of heterozygosity and histone hypoacetylation of the PinX1 gene are associated with reduced expression in gastric carcinoma
-
Kondo T, Oue N, Mitani Y, Kuniyasu H, Noguchi T, Kuraoka K, Nakayama H, Yasui W. Loss of heterozygosity and histone hypoacetylation of the PinX1 gene are associated with reduced expression in gastric carcinoma. Oncogene. 2005; 24: 157-164.
-
(2005)
Oncogene
, vol.24
, pp. 157-164
-
-
Kondo, T.1
Oue, N.2
Mitani, Y.3
Kuniyasu, H.4
Noguchi, T.5
Kuraoka, K.6
Nakayama, H.7
Yasui, W.8
-
21
-
-
59449098927
-
The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population
-
Ma Y, Wu L, Liu C, Xu L, Li D, Li J. C. The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population. J Cancer Res Clin Oncol. 2009; 135: 431-437.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 431-437
-
-
Ma, Y.1
Wu, L.2
Liu, C.3
Xu, L.4
Li, D.5
Li, J.C.6
-
22
-
-
0032911694
-
Direct activation of TERT transcription by c-MYC
-
Wu K. J, Grandori C, Amacker M, Simon-Vermot N, Polack A, Lingner J, Dalla-Favera R. Direct activation of TERT transcription by c-MYC. Nat Genet. 1999; 21: 220-224.
-
(1999)
Nat Genet
, vol.21
, pp. 220-224
-
-
Wu, K.J.1
Grandori, C.2
Amacker, M.3
Simon-Vermot, N.4
Polack, A.5
Lingner, J.6
Dalla-Favera, R.7
-
23
-
-
2642610318
-
Myc activates telomerase
-
Wang J, Xie L. Y, Allan S, Beach D, Hannon G. J. Myc activates telomerase. Genes Dev. 1998; 12: 1769-1774.
-
(1998)
Genes Dev
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
24
-
-
58149152679
-
Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells
-
Hu X, Yu N, Fu L, Su W, Huang G, Wu Y, Huang H, Huang H. Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells. Nucleotides Nucleic Acids. 2009; 28: 1-11.
-
(2009)
Nucleotides Nucleic Acids
, vol.28
, pp. 1-11
-
-
Hu, X.1
Yu, N.2
Fu, L.3
Su, W.4
Huang, G.5
Wu, Y.6
Huang, H.7
Huang, H.8
-
25
-
-
0037821661
-
Multiple tumor suppressor pathways negatively regulate telomerase
-
Lin S. Y, Elledge S. J. Multiple tumor suppressor pathways negatively regulate telomerase. Cell. 2003; 113: 881-889.
-
(2003)
Cell
, vol.113
, pp. 881-889
-
-
Lin, S.Y.1
Elledge, S.J.2
-
26
-
-
0035957406
-
Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells
-
Xu D, Popov N, Hou M, Wang Q, Björkholm M, Gruber A, Menkel AR, Henriksson M. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc Natl Acad Sci U S A. 2001; 98: 3826-3831.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3826-3831
-
-
Xu, D.1
Popov, N.2
Hou, M.3
Wang, Q.4
Björkholm, M.5
Gruber, A.6
Menkel, A.R.7
Henriksson, M.8
-
27
-
-
0037079003
-
Rules for making human tumor cells
-
Hahn W. C, Weinberg R. A. Rules for making human tumor cells. N Engl J Med. 2002; 347: 1593-1603.
-
(2002)
N Engl J Med
, vol.347
, pp. 1593-1603
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
28
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg R. A. The hallmarks of cancer. Cell. 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
10644232937
-
Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR
-
Banik S. S, Counter C. M. Characterization of Interactions between PinX1 and Human Telomerase Subunits hTERT and hTR. J Biol Chem. 2004; 279: 51745-51748.
-
(2004)
J Biol Chem
, vol.279
, pp. 51745-51748
-
-
Banik, S.S.1
Counter, C.M.2
-
30
-
-
0042169025
-
Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms
-
Horikawa I, Barrett J. C. Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis. 2003; 24: 1167-1176.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1167-1176
-
-
Horikawa, I.1
Barrett, J.C.2
-
31
-
-
0034142386
-
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
-
Kyo S, Takakura M, Taira T, Kanaya T, Itoh H, Yutsudo M, Ariga H, Inoue M. Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res. 2000; 28: 669-677.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 669-677
-
-
Kyo, S.1
Takakura, M.2
Taira, T.3
Kanaya, T.4
Itoh, H.5
Yutsudo, M.6
Ariga, H.7
Inoue, M.8
-
32
-
-
0033521960
-
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
-
Greenberg R. A, O'Hagan R. C, Deng H, Xiao Q, Hann S. R, Adams R. R, Lichtsteiner S, Chin L, Morin G. B, DePinho R. A. Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation Oncogene. 1999; 18: 1219-1226.
-
(1999)
Oncogene
, vol.18
, pp. 1219-1226
-
-
Greenberg, R.A.1
O'Hagan, R.C.2
Deng, H.3
Xiao, Q.4
Hann, S.R.5
Adams, R.R.6
Lichtsteiner, S.7
Chin, L.8
Morin, G.B.9
Depinho, R.A.10
-
33
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
Takakura M, Kyo S, Kanaya T, Hirano H, Takeda J, Yutsudo M, Inoue M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 1999; 59: 551-557.
-
(1999)
Cancer Res
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
34
-
-
0033600896
-
In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells
-
Oh S, Song Y. H, Kim U. J, Yim J, Kim T. K. In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells. Biochem Biophys Res Commun. 1999; 263: 361-365.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 361-365
-
-
Oh, S.1
Song, Y.H.2
Kim, U.J.3
Yim, J.4
Kim, T.K.5
-
35
-
-
33746975369
-
Genetic analysis of Myc and telomerase interactions in vivo
-
Flores I, Evan G, Blasco M. A. Genetic Analysis of Myc and Telomerase Interactions In Vivo. Molecular and Cellular Biology. 2006; 26: 6130-6138.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 6130-6138
-
-
Flores, I.1
Evan, G.2
Blasco, M.A.3
-
36
-
-
44849112330
-
Mitotic checkpoint gene MAD1 in hepatocellular carcinoma is associated with tumor recurrence after surgical resection
-
Nam C. W, Park N. H, Park B. R, Shin J. W, Jung S. W, Na Y. W, Seo J. H. Mitotic checkpoint gene MAD1 in hepatocellular carcinoma is associated with tumor recurrence after surgical resection. J Surg Oncol. 2008; 97: 567-571.
-
(2008)
J Surg Oncol
, vol.97
, pp. 567-571
-
-
Nam, C.W.1
Park, N.H.2
Park, B.R.3
Shin, J.W.4
Jung, S.W.5
Na, Y.W.6
Seo, J.H.7
|