Chlamydial infection of monocytes stimulates IL-1β secretion through activation of the NLRP3 inflammasome

Microbes and Infection

Volumn 12, Issue 8-9, 2010, Pages 652-661

  Abdul Sater, Ali A ^a   Saïd Sadier, Najwane ^a,b   Padilla, Eduardo V ^a   Ojcius, David M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUT JACQUES MONOD   (France)

Author keywords

Chlamydia; Inflammasome; Innate immunity; Monocytes; Nod like receptor

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PARTHENOLIDE; PROTEIN KINASE SYK; REACTIVE OXYGEN METABOLITE; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; CARRIER PROTEIN; ENZYME INHIBITOR; NITRILE; NLRP3 PROTEIN, HUMAN; SESQUITERPENE; SULFONE;

ARTICLE; CHLAMYDIASIS; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL LINE; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; IMMUNOLOGY; MICROBIOLOGY; PATHOGENICITY; SECRETION (PROCESS);

CARRIER PROTEINS; CASPASE 1; CELL LINE; CHLAMYDIA MURIDARUM; CHLAMYDIA TRACHOMATIS; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-1BETA; MONOCYTES; NITRILES; SESQUITERPENES; SULFONES;

ANIMALIA; BACTERIA (MICROORGANISMS); CHLAMYDIA; CHLAMYDIA MURIDARUM; CHLAMYDIA TRACHOMATIS;

EID: 77954956738     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2010.04.008     Document Type: Article

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