Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPK

American Journal of Physiology - Endocrinology and Metabolism

Volumn 299, Issue 2, 2010, Pages

  Murase, Takatoshi ^a   Misawa, Koichi ^a   Haramizu, Satoshi ^a   Minegishi, Yoshihiko ^a   Hase, Tadashi ^a  

^a KAO CORPORATION   (Japan)

Author keywords

AMP activated protein kinase; Ca2+ calmodulin dependent protein kinase kinase; Endurance; Exercise; LKB1

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; AMP ACTIVATED PROTEIN KINASE ALPHA1; AMP ACTIVATED PROTEIN KINASE ALPHA2; ANTIOBESITY AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; NATURAL PRODUCT; NOOTKATONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE LKB1; UNCLASSIFIED DRUG; ADENINE NUCLEOTIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; REACTIVE OXYGEN METABOLITE; SESQUITERPENE;

ABDOMINAL FAT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; C57BL 6 MOUSE; CALORIMETRY; CONTROLLED STUDY; DIET; DRUG MECHANISM; ENDURANCE; ENERGY EXPENDITURE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXHAUSTION; FATTY ACID OXIDATION; FEMALE; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; GRAPEFRUIT; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERLEPTINEMIA; INSULIN BLOOD LEVEL; LIPID STORAGE; LIVER; LIVER METABOLISM; MALE; MOUSE; MUSCLE METABOLISM; MUSCLE TISSUE; NONHUMAN; OBESITY; PHYSICAL CAPACITY; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SWIMMING; WEIGHT GAIN; WHOLE BODY ENERGY EXPENDITURE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION; WESTERN BLOTTING;

ADENINE NUCLEOTIDES; ANIMALS; ANTI-OBESITY AGENTS; BLOTTING, WESTERN; CALORIMETRY, INDIRECT; CELLS, CULTURED; CITRUS PARADISI; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIET; ENERGY METABOLISM; ENZYME ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OBESITY; OXIDATION-REDUCTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PHYSICAL ENDURANCE; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SESQUITERPENES; STIMULATION, CHEMICAL; SWIMMING;

EID: 77954916370     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00774.2009     Document Type: Article

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