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Volumn 24, Issue 2, 2010, Pages 203-211

Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats

Author keywords

Antinociception; Formalin; NMDA; NR2 receptor; Orofacial pain

Indexed keywords

3-(2-CARBOXYPIPERAZIN-4-YL)PROPYL-1-PHOSPHONIC ACID; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; 5,7 DICHLOROKYNURENIC ACID; 5,7-DICHLOROKYNURENIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; DRUG DERIVATIVE; FORMALDEHYDE; KYNURENIC ACID; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENOL DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE;

EID: 77954892647     PISSN: 23330384     EISSN: 23330376     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (54)
  • 2
    • 33846920665 scopus 로고    scopus 로고
    • NMDA receptor subunits: Function and pharmacology
    • Paoletti P, Neyton J. NMDA receptor subunits: Function and pharmacology. Curr Opin Pharmacol 2007;7:39-47
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 39-47
    • Paoletti, P.1    Neyton, J.2
  • 3
    • 34250158705 scopus 로고    scopus 로고
    • N-methyl-D-aspartate antagonists and neuropathic pain: The search for relief
    • Childers WE Jr, Baudy RB. N-methyl-D-aspartate antagonists and neuropathic pain: The search for relief. J Med Chem 2007;50:2557-2562
    • (2007) J Med Chem , vol.50 , pp. 2557-2562
    • Childers, W.E.1    Baudy, R.B.2
  • 4
    • 0028179069 scopus 로고
    • N-methyl-D-aspartic acid receptor structure and function
    • McBain CJ, Mayer ML. N-methyl-D-aspartic acid receptor structure and function. Physiol Rev 1994;74:723-760
    • (1994) Physiol Rev , vol.74 , pp. 723-760
    • McBain, C.J.1    Mayer, M.L.2
  • 5
    • 0028810883 scopus 로고
    • Structure and function of the NMDA receptor channel
    • Mori H, Mishina M. Structure and function of the NMDA receptor channel. Neuropharmacology 1995;34:1219-1237
    • (1995) Neuropharmacology , vol.34 , pp. 1219-1237
    • Mori, H.1    Mishina, M.2
  • 6
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • Kew JN, Kemp JA. Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacology (Berl) 2005;179:4-129
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 4-129
    • Kew, J.N.1    Kemp, J.A.2
  • 7
    • 0032790229 scopus 로고    scopus 로고
    • Subunit-and site-specific pharmacology of the NMDA receptor channel
    • Yamakura T, Shimoji K. Subunit-and site-specific pharmacology of the NMDA receptor channel. Prog Neurobiol 1999;59:279-298
    • (1999) Prog Neurobiol , vol.59 , pp. 279-298
    • Yamakura, T.1    Shimoji, K.2
  • 8
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: Diversity, development and disease. Curr Opin Neurobiol 2001;11:327-335
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 9
    • 0036389402 scopus 로고    scopus 로고
    • Formalininduced changes of NMDA receptor subunit expression in the spinal cord of the rat
    • Gaunitz C, Schüttler A, Gillen C, Allgaier C. Formalininduced changes of NMDA receptor subunit expression in the spinal cord of the rat. Amino Acids 2002;23:177-182
    • (2002) Amino Acids , vol.23 , pp. 177-182
    • Gaunitz, C.1    Schüttler, A.2    Gillen, C.3    Allgaier, C.4
  • 10
    • 0037219288 scopus 로고    scopus 로고
    • Powerful antinociceptive effects of the cone snail venomderived subtype-selective NMDA receptor antagonists conantokins G and T
    • Malmberg AB, Gilbert H, McCabe RT, Basbaum AI. Powerful antinociceptive effects of the cone snail venomderived subtype-selective NMDA receptor antagonists conantokins G and T. Pain 2003;101:109-116
    • (2003) Pain , vol.101 , pp. 109-116
    • Malmberg, A.B.1    Gilbert, H.2    McCabe, R.T.3    Basbaum, A.I.4
  • 11
    • 0030064089 scopus 로고    scopus 로고
    • Blockade of the polyamine site of NMDA receptors produces antinociception and enhances the effect of morphine, in mice
    • Bernardi M, Bertolini A, Szczawinska K, Genedani S. Blockade of the polyamine site of NMDA receptors produces antinociception and enhances the effect of morphine, in mice. Eur J Pharmacol 1996;298:51-55
    • (1996) Eur J Pharmacol , vol.298 , pp. 51-55
    • Bernardi, M.1    Bertolini, A.2    Szczawinska, K.3    Genedani, S.4
  • 12
    • 0030771671 scopus 로고    scopus 로고
    • Antinociceptive activity of CP-101, 606, an NMDA receptor NR2B subunit antagonist
    • Taniguchi K, Shinjo K, Mizutani M, et al. Antinociceptive activity of CP-101, 606, an NMDA receptor NR2B subunit antagonist. Br J Pharmacol 1997;122:809-812
    • (1997) Br J Pharmacol , vol.122 , pp. 809-812
    • Taniguchi, K.1    Shinjo, K.2    Mizutani, M.3
  • 13
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: Correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S, Wyatt A, Webb JK, et al. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: Correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 1999;38:611-623
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3
  • 14
    • 57349138758 scopus 로고    scopus 로고
    • Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
    • Liu XJ, Gingrich JR, Vargas-Caballero M, et al. Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex. Nat Med 2008;14:1325-1332
    • (2008) Nat Med , vol.14 , pp. 1325-1332
    • Liu, X.J.1    Gingrich, J.R.2    Vargas-Caballero, M.3
  • 15
    • 34250221075 scopus 로고    scopus 로고
    • Differential regulation of glutamate receptors in trigeminal ganglia following masseter inflammation
    • Lee J, Ro JY. Differential regulation of glutamate receptors in trigeminal ganglia following masseter inflammation. Neurosci Lett 2007;421:91-95
    • (2007) Neurosci Lett , vol.421 , pp. 91-95
    • Lee, J.1    Ro, J.Y.2
  • 16
    • 34247230366 scopus 로고    scopus 로고
    • Sex-related differences in NMDA-evoked rat masseter muscle afferent discharge result from estrogen-mediated modulation of peripheral NMDA receptor activity
    • Dong XD, Mann MK, Kumar U, et al. Sex-related differences in NMDA-evoked rat masseter muscle afferent discharge result from estrogen-mediated modulation of peripheral NMDA receptor activity. Neuroscience 2007; 146:822-832
    • (2007) Neuroscience , vol.146 , pp. 822-832
    • Dong, X.D.1    Mann, M.K.2    Kumar, U.3
  • 17
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • Yaksh TL, Rudy TA. Chronic catheterization of the spinal subarachnoid space. Physiol Behav 1976;17:1031-1036
    • (1976) Physiol Behav , vol.17 , pp. 1031-1036
    • Yaksh, T.L.1    Rudy, T.A.2
  • 18
    • 0036299148 scopus 로고    scopus 로고
    • Effect of antisense knock-down of alpha(2a)-and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat
    • Wang XM, Zhang ZJ, Bains R, Mokha SS. Effect of antisense knock-down of alpha(2a)-and alpha(2c)-adrenoceptors on the antinociceptive action of clonidine on trigeminal nociception in the rat. Pain 2002;98:27-35
    • (2002) Pain , vol.98 , pp. 27-35
    • Wang, X.M.1    Zhang, Z.J.2    Bains, R.3    Mokha, S.S.4
  • 19
    • 34848861063 scopus 로고    scopus 로고
    • Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception
    • Ahn DK, Choi HS, Yeo SP, et al. Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception. Pain 2007;132: 23-32
    • (2007) Pain , vol.132 , pp. 23-32
    • Ahn, D.K.1    Choi, H.S.2    Yeo, S.P.3
  • 20
    • 53049098005 scopus 로고    scopus 로고
    • Low doses of cannabinoids enhance the antinociceptive effects of intracisternally administered mGluRs groups II and III agonists in formalin-induced TMJ nociception in rats
    • Lee MK, Choi BY, Yang GY, et al. Low doses of cannabinoids enhance the antinociceptive effects of intracisternally administered mGluRs groups II and III agonists in formalin-induced TMJ nociception in rats. Pain 2008;139: 367-375
    • (2008) Pain , vol.139 , pp. 367-375
    • Lee, M.K.1    Choi, B.Y.2    Yang, G.Y.3
  • 21
    • 0024330182 scopus 로고
    • Application of the formalin test to the study of orofacial pain in the rat
    • Clavelou P, Pajot J, Dallel R, Raboisson P. Application of the formalin test to the study of orofacial pain in the rat. Neurosci Lett 1989;103:349-353
    • (1989) Neurosci Lett , vol.103 , pp. 349-353
    • Clavelou, P.1    Pajot, J.2    Dallel, R.3    Raboisson, P.4
  • 22
    • 0035125533 scopus 로고    scopus 로고
    • Antihyperalgesic activity of epibatidine in the formalin model of facial pain
    • Gilbert SD, Clark TM, Flores CM. Antihyperalgesic activity of epibatidine in the formalin model of facial pain. Pain 2001;89:159-165
    • (2001) Pain , vol.89 , pp. 159-165
    • Gilbert, S.D.1    Clark, T.M.2    Flores, C.M.3
  • 23
    • 0037674675 scopus 로고    scopus 로고
    • Effects of TNF-alpha injected intracisternally on the nociceptive jaw-opening reflex and orofacial formalin test in freely moving rats
    • Choi HS, Ju JS, Lee HJ, et al. Effects of TNF-alpha injected intracisternally on the nociceptive jaw-opening reflex and orofacial formalin test in freely moving rats. Prog Neuropsychopharmacol Biol Psychiatry 2003;27: 613-618
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 613-618
    • Choi, H.S.1    Ju, J.S.2    Lee, H.J.3
  • 24
    • 0037472310 scopus 로고    scopus 로고
    • Effects of intracisternal injection of interleukin-6 on nociceptive jaw opening reflex and orofacial formalin test in freely moving rats
    • Choi HS, Ju JS, Lee HJ, Kim BC, Park JS, Ahn DK. Effects of intracisternal injection of interleukin-6 on nociceptive jaw opening reflex and orofacial formalin test in freely moving rats. Brain Res Bull 2003;59:365-370
    • (2003) Brain Res Bull , vol.59 , pp. 365-370
    • Choi, H.S.1    Ju, J.S.2    Lee, H.J.3    Kim, B.C.4    Park, J.S.5    Ahn, D.K.6
  • 25
    • 1842861599 scopus 로고    scopus 로고
    • Intracisternal NMDA produces analgesia in the orofacial formalin test of freely moving rats
    • Lee HJ, Choi HS, Jung CY, et al. Intracisternal NMDA produces analgesia in the orofacial formalin test of freely moving rats. Prog Neuropsychopharmacol Biol Psychiatry 2004;28:497-503
    • (2004) Prog Neuropsychopharmacol Biol Psychiatry , vol.28 , pp. 497-503
    • Lee, H.J.1    Choi, H.S.2    Jung, C.Y.3
  • 26
    • 50349087573 scopus 로고    scopus 로고
    • Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit
    • Peng HY, Chang HM, Chang SY, et al. Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit. Am J Physiol Endocrinol Metab 2008;295:117-129
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , pp. 117-129
    • Peng, H.Y.1    Chang, H.M.2    Chang, S.Y.3
  • 27
    • 34250789223 scopus 로고    scopus 로고
    • Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia
    • Gabra BH, Kessler FK, Ritter JK, Dewey WL, Smith FL. Decrease in N-methyl-D-aspartic acid receptor-NR2B subunit levels by intrathecal short-hairpin RNA blocks group I metabotropic glutamate receptor-mediated hyperalgesia. J Pharmacol Exp Ther 2007;322:186-194
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 186-194
    • Gabra, B.H.1    Kessler, F.K.2    Ritter, J.K.3    Dewey, W.L.4    Smith, F.L.5
  • 28
    • 20444372595 scopus 로고    scopus 로고
    • Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: Possible peripheral mechanisms
    • Christoph T, Reissmüller E, Schiene K, Englberger W, Chizh BA. Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: Possible peripheral mechanisms. Brain Red 2005;1048:218-227
    • (2005) Brain Red , vol.1048 , pp. 218-227
    • Christoph, T.1    Reissmüller, E.2    Schiene, K.3    Englberger, W.4    Chizh, B.A.5
  • 29
    • 0037226868 scopus 로고    scopus 로고
    • Antinociceptive effect in mice of intraperitoneal N-methyl-D-aspartate receptor antagonists in the formalin test
    • Berrino L, Oliva P, Massimo F, et al. Antinociceptive effect in mice of intraperitoneal N-methyl-D-aspartate receptor antagonists in the formalin test. Eur J Pain 2003; 7:131-137
    • (2003) Eur J Pain , vol.7 , pp. 131-137
    • Berrino, L.1    Oliva, P.2    Massimo, F.3
  • 30
    • 67349245826 scopus 로고    scopus 로고
    • Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats
    • Ahn DK, Lim EJ, Kim BC, et al. Compression of the trigeminal ganglion produces prolonged nociceptive behavior in rats. Eur J Pain 2009;13:568-575
    • (2009) Eur J Pain , vol.13 , pp. 568-575
    • Ahn, D.K.1    Lim, E.J.2    Kim, B.C.3
  • 31
    • 0141458065 scopus 로고    scopus 로고
    • The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review
    • Petrenko AB, Yamakura T, Baba H, Shimoji K. The role of N-methyl-D-aspartate (NMDA) receptors in pain: A review. Anesth Analg 2003;97:1108-1116
    • (2003) Anesth Analg , vol.97 , pp. 1108-1116
    • Petrenko, A.B.1    Yamakura, T.2    Baba, H.3    Shimoji, K.4
  • 32
    • 0023605956 scopus 로고
    • Evidence for involvement of Nmethylaspartate receptors in "wind-up" of class 2 neurones in the dorsal horn of the rat
    • Davies SN, Lodge D. Evidence for involvement of Nmethylaspartate receptors in "wind-up" of class 2 neurones in the dorsal horn of the rat. Brain Res 1987;424: 402-406
    • (1987) Brain Res , vol.424 , pp. 402-406
    • Davies, S.N.1    Lodge, D.2
  • 33
    • 0023189510 scopus 로고
    • Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation
    • Dickenson AH, Sullivan AF. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation. Neuropharmacology 1987;26:1235-1238
    • (1987) Neuropharmacology , vol.26 , pp. 1235-1238
    • Dickenson, A.H.1    Sullivan, A.F.2
  • 34
    • 0033794460 scopus 로고    scopus 로고
    • Targeting N-methyl-Daspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions
    • Fisher K, Coderre TJ, Hagen NA. Targeting N-methyl-Daspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions. J Pain Symptom Manage 2000; 20:358-373
    • (2000) J Pain Symptom Manage , vol.20 , pp. 358-373
    • Fisher, K.1    Coderre, T.J.2    Hagen, N.A.3
  • 35
    • 0034041222 scopus 로고    scopus 로고
    • The use of NMDA-receptor antagonists in the treatment of chronic pain
    • Hewitt DJ. The use of NMDA-receptor antagonists in the treatment of chronic pain. Clin J Pain 2000;16:S73-S79
    • (2000) Clin J Pain , vol.16 , pp. S73-S79
    • Hewitt, D.J.1
  • 36
    • 0000801907 scopus 로고    scopus 로고
    • NMDA receptor mechanisms contribute to neuroplasticity induced in caudalis nociceptive neurons by tooth pulp stimulation
    • Chiang CY, Park SJ, Kwan CL, Hu JW, Sessle BJ. NMDA receptor mechanisms contribute to neuroplasticity induced in caudalis nociceptive neurons by tooth pulp stimulation. J Neurophysiol 1998;80:2621-2631
    • (1998) J Neurophysiol , vol.80 , pp. 2621-2631
    • Chiang, C.Y.1    Park, S.J.2    Kwan, C.L.3    Hu, J.W.4    Sessle, B.J.5
  • 37
    • 0035900594 scopus 로고    scopus 로고
    • Superficial and deep convergent nociceptive neurons are differentially affected by N-methyl-D-aspartate applied on the brainstem surface of the rat medullary dorsal horn
    • Luccarini P, Sessle BJ, Woda A. Superficial and deep convergent nociceptive neurons are differentially affected by N-methyl-D-aspartate applied on the brainstem surface of the rat medullary dorsal horn. Neuroscience 2001;107: 311-316
    • (2001) Neuroscience , vol.107 , pp. 311-316
    • Luccarini, P.1    Sessle, B.J.2    Woda, A.3
  • 38
    • 0343773371 scopus 로고    scopus 로고
    • Neuroplasticity induced by tooth pulp stimulation in trigeminal subnucleus oralis involves NMDA receptor mechanisms
    • Park SJ, Chiang CY, Hu JW, Sessle BJ. Neuroplasticity induced by tooth pulp stimulation in trigeminal subnucleus oralis involves NMDA receptor mechanisms. J Neurophysiol 2001;85:1836-1846
    • (2001) J Neurophysiol , vol.85 , pp. 1836-1846
    • Park, S.J.1    Chiang, C.Y.2    Hu, J.W.3    Sessle, B.J.4
  • 39
    • 0035800236 scopus 로고    scopus 로고
    • Temporomandibular-evoked jaw muscle reflex: Role of brain stem NMDA and non-NMDA receptors
    • Cairns BE, Sessle BJ, Hu JW. Temporomandibular-evoked jaw muscle reflex: Role of brain stem NMDA and non-NMDA receptors. Neuroreport 2001;12:1875-1878
    • (2001) Neuroreport , vol.12 , pp. 1875-1878
    • Cairns, B.E.1    Sessle, B.J.2    Hu, J.W.3
  • 40
    • 66649086928 scopus 로고    scopus 로고
    • Mechanism of differential control of NMDA receptor activity by NR2 subunits
    • Gielen M, Siegler Retchless B, Mony L, Johnson JW, Paoletti P. Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature 2009;459: 703-707
    • (2009) Nature , vol.459 , pp. 703-707
    • Gielen, M.1    Siegler Retchless, B.2    Mony, L.3    Johnson, J.W.4    Paoletti, P.5
  • 41
    • 0034653985 scopus 로고    scopus 로고
    • Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord
    • Momiyama A. Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord. J Physiol 2000;523:621-628
    • (2000) J Physiol , vol.523 , pp. 621-628
    • Momiyama, A.1
  • 42
    • 0037135250 scopus 로고    scopus 로고
    • Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn: Effects of peripheral nerve lesion and inflammation
    • Karlsson U, Sjödin J, Angeby Möller K, Johansson S, Wikström L, Nasström J. Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn: Effects of peripheral nerve lesion and inflammation. Neuroscience 2002;112:861-868
    • (2002) Neuroscience , vol.112 , pp. 861-868
    • Karlsson, U.1    Sjödin, J.2    Angeby Möller, K.3    Johansson, S.4    Wikström, L.5    Nasström, J.6
  • 43
    • 55649100991 scopus 로고    scopus 로고
    • Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in post-synaptic density-93 protein
    • Liaw WJ, Zhu XG, Yaster M, Johns RA, Gauda EB, Tao YX. Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in post-synaptic density-93 protein. Mol Pain 2008;4:45
    • (2008) Mol Pain , vol.4 , pp. 45
    • Liaw, W.J.1    Zhu, X.G.2    Yaster, M.3    Johns, R.A.4    Gauda, E.B.5    Tao, Y.X.6
  • 44
    • 33646087668 scopus 로고    scopus 로고
    • Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat
    • Ultenius C, Linderoth B, Meyerson BA, Wallin J. Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. Neurosci Lett 2006;399:85-90
    • (2006) Neurosci Lett , vol.399 , pp. 85-90
    • Ultenius, C.1    Linderoth, B.2    Meyerson, B.A.3    Wallin, J.4
  • 45
    • 0037952852 scopus 로고    scopus 로고
    • Unaltered pain-related behavior in mice lacking NMDA receptor GluR epsilon 1 subunit
    • Petrenko AB, Yamakura T, Baba H, Sakimura K. Unaltered pain-related behavior in mice lacking NMDA receptor GluR epsilon 1 subunit. Neurosci Res 2003;46:199-204
    • (2003) Neurosci Res , vol.46 , pp. 199-204
    • Petrenko, A.B.1    Yamakura, T.2    Baba, H.3    Sakimura, K.4
  • 46
    • 0030943255 scopus 로고    scopus 로고
    • NMDA-receptor regulation of substance P release from primary afferent nociceptors
    • Liu H, Mantyh PW, Basbaum AI. NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature 1997;386:721-724
    • (1997) Nature , vol.386 , pp. 721-724
    • Liu, H.1    Mantyh, P.W.2    Basbaum, A.I.3
  • 47
    • 0034669122 scopus 로고    scopus 로고
    • Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats
    • Ma QP, Hargreaves RJ. Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats. Neuroscience 2000;101:699-707
    • (2000) Neuroscience , vol.101 , pp. 699-707
    • Ma, Q.P.1    Hargreaves, R.J.2
  • 48
    • 0035577313 scopus 로고    scopus 로고
    • NMDA receptor antagonists as analgesics: Focus on the NR2B subtype
    • Chizh BA, Headley PM, Tzschentke TM. NMDA receptor antagonists as analgesics: Focus on the NR2B subtype. Trends Pharmacol Sci 2001;22:636-642
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 636-642
    • Chizh, B.A.1    Headley, P.M.2    Tzschentke, T.M.3
  • 49
    • 0036830627 scopus 로고    scopus 로고
    • NMDA receptor pathways as drug targets
    • Kemp JA, McKernan RM. NMDA receptor pathways as drug targets. Nat Neurosci 2002;5:1039-1042
    • (2002) Nat Neurosci , vol.5 , pp. 1039-1042
    • Kemp, J.A.1    McKernan, R.M.2
  • 50
    • 23844495851 scopus 로고    scopus 로고
    • NMDA antagonists and neuropathic pain: Multiple drug targets and multiple uses
    • Chizh BA, Headley PM. NMDA antagonists and neuropathic pain: Multiple drug targets and multiple uses. Curr Pharm Des 2005;11:2977-2994
    • (2005) Curr Pharm Des , vol.11 , pp. 2977-2994
    • Chizh, B.A.1    Headley, P.M.2
  • 51
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson JW, Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 1987; 325:529-531
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 52
    • 33646586668 scopus 로고    scopus 로고
    • Glycine/NMDA receptor antagonists as potential CNS therapeutic agents: ACEA-1021 and related compounds
    • Cai SX. Glycine/NMDA receptor antagonists as potential CNS therapeutic agents: ACEA-1021 and related compounds. Curr Top Med Chem 2006;6:651-662
    • (2006) Curr Top Med Chem , vol.6 , pp. 651-662
    • Cai, S.X.1
  • 53
    • 0035798403 scopus 로고    scopus 로고
    • GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice
    • Quartaroli M, Fasdelli N, Bettelini L, Maraia G, Corsi M. GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice. Eur J Pharmacol 2001;430:219-227
    • (2001) Eur J Pharmacol , vol.430 , pp. 219-227
    • Quartaroli, M.1    Fasdelli, N.2    Bettelini, L.3    Maraia, G.4    Corsi, M.5
  • 54
    • 0032966913 scopus 로고    scopus 로고
    • Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A
    • Quartaroli M, Carignani C, Dal Forno G, et al. Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A. J Pharmacol Exp Ther 1999;290:158-169
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 158-169
    • Quartaroli, M.1    Carignani, C.2    Dal Forno, G.3


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