메뉴 건너뛰기




Volumn 101, Issue 1-2, 2003, Pages 109-116

Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T

Author keywords

Antinociception; Ceutral sensitization; Conantokins; Cone snail venom derived peptides; Neuropathic pain

Indexed keywords

CONANTOKIN G; CONANTOKIN T; FORMALDEHYDE; FREUND ADJUVANT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OMEGA CONOTOXIN MVIIA; RECEPTOR SUBTYPE; SNAIL VENOM;

EID: 0037219288     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00303-2     Document Type: Article
Times cited : (132)

References (60)
  • 1
    • 0030434482 scopus 로고    scopus 로고
    • Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain
    • Bowersox S.S., Gadbois T., Singh T., Pettus M., Wang Y.X., Luther R.R. Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain. J Pharmacol Exp Ther. 279:1996;1243-1249.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1243-1249
    • Bowersox, S.S.1    Gadbois, T.2    Singh, T.3    Pettus, M.4    Wang, Y.X.5    Luther, R.R.6
  • 2
    • 0032987252 scopus 로고    scopus 로고
    • Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: Correlation with restricted localisation of NR2B subunit in dorsal horn
    • Boyce S., Wyatt A., Webb J.K., O'Donnell R., Mason G., Rigby M., Sirinathsinghji D., Hill R.G., Rupniak N.M. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology. 38:1999;611-623.
    • (1999) Neuropharmacology , vol.38 , pp. 611-623
    • Boyce, S.1    Wyatt, A.2    Webb, J.K.3    O'Donnell, R.4    Mason, G.5    Rigby, M.6    Sirinathsinghji, D.7    Hill, R.G.8    Rupniak, N.M.9
  • 3
    • 0032550185 scopus 로고    scopus 로고
    • Evidence for the interaction of glutamate and NK1 receptors in the periphery
    • Carlton S.M., Zhou S., Coggeshall R.E. Evidence for the interaction of glutamate and NK1 receptors in the periphery. Brain Res. 790:1998;160-169.
    • (1998) Brain Res , vol.790 , pp. 160-169
    • Carlton, S.M.1    Zhou, S.2    Coggeshall, R.E.3
  • 5
    • 0030933616 scopus 로고    scopus 로고
    • Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat
    • Chaplan S.R., Malmberg A.B., Yaksh T.L. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther. 280:1997;829-838.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 829-838
    • Chaplan, S.R.1    Malmberg, A.B.2    Yaksh, T.L.3
  • 6
    • 0032520875 scopus 로고    scopus 로고
    • Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6
    • Chapman V., Suzuki R., Dickenson A.H. Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6. J Physiol. 507:1998;881-894.
    • (1998) J Physiol , vol.507 , pp. 881-894
    • Chapman, V.1    Suzuki, R.2    Dickenson, A.H.3
  • 7
    • 0035218071 scopus 로고    scopus 로고
    • Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil
    • Chizh B.A., Reissmuller E., Schlutz H., Scheede M., Haase G., Englberger W. Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil. Neuropharmacology. 40:2001;212-220.
    • (2001) Neuropharmacology , vol.40 , pp. 212-220
    • Chizh, B.A.1    Reissmuller, E.2    Schlutz, H.3    Scheede, M.4    Haase, G.5    Englberger, W.6
  • 8
    • 0026738989 scopus 로고
    • The role of NMDA receptor-operated calcium channels in persistent nociception after formalin-induced tissue injury
    • Coderre T.J., Melzack R. The role of NMDA receptor-operated calcium channels in persistent nociception after formalin-induced tissue injury. J Neurosci. 9:1992;3671-3675.
    • (1992) J Neurosci , vol.9 , pp. 3671-3675
    • Coderre, T.J.1    Melzack, R.2
  • 9
    • 0028598668 scopus 로고
    • The utility of excitatory amino acid (EAA) antagonists as analgesic agents
    • Coderre T.J., Van Empel I. The utility of excitatory amino acid (EAA) antagonists as analgesic agents. Pain. 59:1994;353-359.
    • (1994) Pain , vol.59 , pp. 353-359
    • Coderre, T.J.1    Van Empel, I.2
  • 10
    • 0025769640 scopus 로고
    • MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy
    • Davar G., Hama A., Deykin A., Vos B., Maciewicz R. MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy. Brain Res. 553:1991;327-330.
    • (1991) Brain Res , vol.553 , pp. 327-330
    • Davar, G.1    Hama, A.2    Deykin, A.3    Vos, B.4    Maciewicz, R.5
  • 11
    • 0025021299 scopus 로고
    • Differential effects of excitatory amino-acid antagonists on dorsal horn nociceptive neurons in the rat
    • Dickenson A.H., Sullivan A.F. Differential effects of excitatory amino-acid antagonists on dorsal horn nociceptive neurons in the rat. Brain Res. 506:1990;31-39.
    • (1990) Brain Res , vol.506 , pp. 31-39
    • Dickenson, A.H.1    Sullivan, A.F.2
  • 12
    • 0035826949 scopus 로고    scopus 로고
    • NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord
    • Di Luca M., Gardoni F., Finardi A., Pagliardini S., Cattabeni F., Battaglia G., Missale C. NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord. NeuroReport. 12:2001;1301-1305.
    • (2001) NeuroReport , vol.12 , pp. 1301-1305
    • Di Luca, M.1    Gardoni, F.2    Finardi, A.3    Pagliardini, S.4    Cattabeni, F.5    Battaglia, G.6    Missale, C.7
  • 13
    • 0033851790 scopus 로고    scopus 로고
    • Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors
    • Donevan S.D., McCabe R.T. Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors. Mol Pharmacol. 3:2000;614-623.
    • (2000) Mol Pharmacol , vol.3 , pp. 614-623
    • Donevan, S.D.1    McCabe, R.T.2
  • 14
    • 0028038355 scopus 로고
    • Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: A double-blind, cross-over comparison with morphine and placebo
    • Eide P.K., Jorum E., Stubhaug A., Bremnes J., Breivik H. Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo. Pain. 58:1994;347-354.
    • (1994) Pain , vol.58 , pp. 347-354
    • Eide, P.K.1    Jorum, E.2    Stubhaug, A.3    Bremnes, J.4    Breivik, H.5
  • 16
    • 0033794460 scopus 로고    scopus 로고
    • Targeting the N-methyl-D-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions
    • Fisher K., Coderre T.J., Hagen N.A. Targeting the N-methyl-D-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions. J Pain Symptom Manage. 20:2000;358-373.
    • (2000) J Pain Symptom Manage , vol.20 , pp. 358-373
    • Fisher, K.1    Coderre, T.J.2    Hagen, N.A.3
  • 17
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 32:1988;141-167.
    • (1988) Pain , vol.32 , pp. 141-167
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 18
    • 0018956018 scopus 로고
    • Intrathecal morphine in mice: A new technique
    • Hylden J.L.K., Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur J Pharmacol. 67:1980;313-316.
    • (1980) Eur J Pharmacol , vol.67 , pp. 313-316
    • Hylden, J.L.K.1    Wilcox, G.L.2
  • 19
    • 0033810234 scopus 로고    scopus 로고
    • An evaluation of intrathecal ziconotide for the treatment of chronic pain
    • Jain K.K. An evaluation of intrathecal ziconotide for the treatment of chronic pain. Expert Opin Invest Drugs. 10:2000;2403-2410.
    • (2000) Expert Opin Invest Drugs , vol.10 , pp. 2403-2410
    • Jain, K.K.1
  • 20
    • 0035920125 scopus 로고    scopus 로고
    • The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors
    • Klein R.C., Prorok M., Galdzicki Z., Castellino F.J. The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors. J Biol Chem. 276:2001;26860-26867.
    • (2001) J Biol Chem , vol.276 , pp. 26860-26867
    • Klein, R.C.1    Prorok, M.2    Galdzicki, Z.3    Castellino, F.J.4
  • 21
    • 0026677223 scopus 로고
    • The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans
    • Kristensen J.D., Svensson B., Gordh T. Jr. The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans. Pain. 51:1992;249-253.
    • (1992) Pain , vol.51 , pp. 249-253
    • Kristensen, J.D.1    Svensson, B.2    Gordh T., Jr.3
  • 22
    • 0027238585 scopus 로고
    • An electrophysiological study of dorsal horn neurons in the spinal cord of rats with an experimental peripheral neuropathy
    • Laird J.M., Bennett G.J. An electrophysiological study of dorsal horn neurons in the spinal cord of rats with an experimental peripheral neuropathy. J Neurophysiol. 69:1993;2072-2085.
    • (1993) J Neurophysiol , vol.69 , pp. 2072-2085
    • Laird, J.M.1    Bennett, G.J.2
  • 23
    • 0030879183 scopus 로고    scopus 로고
    • Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors
    • Laughlin T.M., Vanderah T.W., Lashbrook J., Nichols M.L., Ossipov M., Porreca F., Wilcox G.L. Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors. Pain. 72:1997;253-260.
    • (1997) Pain , vol.72 , pp. 253-260
    • Laughlin, T.M.1    Vanderah, T.W.2    Lashbrook, J.3    Nichols, M.L.4    Ossipov, M.5    Porreca, F.6    Wilcox, G.L.7
  • 24
    • 0030583001 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury
    • Leem J.W., Choi E.J., Park E.S., Paik K.S. N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury. Neurosci Lett. 211:1996;37-40.
    • (1996) Neurosci Lett , vol.211 , pp. 37-40
    • Leem, J.W.1    Choi, E.J.2    Park, E.S.3    Paik, K.S.4
  • 25
    • 0034669122 scopus 로고    scopus 로고
    • Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats
    • Ma Q.P., Hargreaves R.J. Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats. Neuroscience. 101:2000;699-707.
    • (2000) Neuroscience , vol.101 , pp. 699-707
    • Ma, Q.P.1    Hargreaves, R.J.2
  • 26
    • 0031775956 scopus 로고    scopus 로고
    • Partial sciatic nerve injury in the mouse as a model of neuropathic pain: Behavioral and neuroanatomical correlates
    • Malmberg A.B., Basbaum A.I. Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates. Pain. 76:1998;215-222.
    • (1998) Pain , vol.76 , pp. 215-222
    • Malmberg, A.B.1    Basbaum, A.I.2
  • 27
    • 0027941058 scopus 로고
    • Voltage-sensitive calcium channels in spinal nociceptive processing: Blockade of N and P type channels inhibit formalin-induced nociception
    • Malmberg A.B., Yaksh T.L. Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N and P type channels inhibit formalin-induced nociception. J Neurosci. 14:1994;4882-4890.
    • (1994) J Neurosci , vol.14 , pp. 4882-4890
    • Malmberg, A.B.1    Yaksh, T.L.2
  • 28
    • 0027057580 scopus 로고
    • Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy
    • Mao J., Price D.D., Hayes R.L., Lu J., Mayer D.J. Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain Res. 598:1992;271-278.
    • (1992) Brain Res , vol.598 , pp. 271-278
    • Mao, J.1    Price, D.D.2    Hayes, R.L.3    Lu, J.4    Mayer, D.J.5
  • 29
    • 0035878076 scopus 로고    scopus 로고
    • PKCγ contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain
    • Martin W.J., Malmberg A.B., Basbaum A.I. PKCγ contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain. J Neurosci. 21:2001;5321-5327.
    • (2001) J Neurosci , vol.21 , pp. 5321-5327
    • Martin, W.J.1    Malmberg, A.B.2    Basbaum, A.I.3
  • 30
    • 0029125541 scopus 로고
    • Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: A double-blind comparison to alfentanil and placebo
    • Max M.B., Byas-Smith M.G., Gracely R.H., Bennett G.J. Intravenous infusion of the NMDA antagonist, ketamine, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo. Clin Neuropharmacol. 18:1995;360-368.
    • (1995) Clin Neuropharmacol , vol.18 , pp. 360-368
    • Max, M.B.1    Byas-Smith, M.G.2    Gracely, R.H.3    Bennett, G.J.4
  • 32
    • 0034653985 scopus 로고    scopus 로고
    • Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord
    • Momiyama A. Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord. J Physiol. 523:(Pt 3):2000;621-628.
    • (2000) J Physiol , vol.523 , Issue.PART 3 , pp. 621-628
    • Momiyama, A.1
  • 33
    • 0028299707 scopus 로고
    • The involvement of N-methyl-D - Aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle
    • Neugebauer V., Lucke T., Grubb B., Schaible H.G. The involvement of N-methyl-D - aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle. Neurosci Lett. 170:1994;237-240.
    • (1994) Neurosci Lett , vol.170 , pp. 237-240
    • Neugebauer, V.1    Lucke, T.2    Grubb, B.3    Schaible, H.G.4
  • 34
    • 0030248210 scopus 로고    scopus 로고
    • The effect of ketamine on phantom pain: A central neuropathic disorder maintained by peripheral input
    • Nikolajsen L., Hansen C.L., Nielsen J., Keller J., Arendt-Nielsen L., Jensen T.S. The effect of ketamine on phantom pain: a central neuropathic disorder maintained by peripheral input. Pain. 67:1996;69-77.
    • (1996) Pain , vol.67 , pp. 69-77
    • Nikolajsen, L.1    Hansen, C.L.2    Nielsen, J.3    Keller, J.4    Arendt-Nielsen, L.5    Jensen, T.S.6
  • 35
    • 0033844345 scopus 로고    scopus 로고
    • Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia
    • Nishiyama T. Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia. Can J Anaesth. 47:2000;693-698.
    • (2000) Can J Anaesth , vol.47 , pp. 693-698
    • Nishiyama, T.1
  • 37
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
    • Petralia R.S., Wang Y.X., Wenthold R.J. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci. 10:1994;6102-6120.
    • (1994) J Neurosci , vol.10 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.X.2    Wenthold, R.J.3
  • 38
    • 0029670633 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor proteins NR2A and NR2B are differentially distributed in the developing rat central nervous system as revealed by subunit-specific antibodies
    • Portera-Cailliau C., Price D.L., Martin L.J. N-methyl-D-aspartate receptor proteins NR2A and NR2B are differentially distributed in the developing rat central nervous system as revealed by subunit-specific antibodies. J Neurochem. 2:1996;692-700.
    • (1996) J Neurochem , vol.2 , pp. 692-700
    • Portera-Cailliau, C.1    Price, D.L.2    Martin, L.J.3
  • 39
    • 0034845386 scopus 로고    scopus 로고
    • Structure-function relationships of the NMDA receptor antagonist conantokin peptides
    • Prorok M., Castellino F.J. Structure-function relationships of the NMDA receptor antagonist conantokin peptides. Curr Drug Targets. 2:2001;313-322.
    • (2001) Curr Drug Targets , vol.2 , pp. 313-322
    • Prorok, M.1    Castellino, F.J.2
  • 40
    • 0029923562 scopus 로고    scopus 로고
    • Formalin-evoked activity in identified primary afferent fibers: Systemic lidocaine suppresses phase-2 activity
    • Puig S., Sorkin L.S. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain. 64:1996;345-355.
    • (1996) Pain , vol.64 , pp. 345-355
    • Puig, S.1    Sorkin, L.S.2
  • 42
    • 0026709480 scopus 로고
    • The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
    • Ren K., Hylden J.L., Williams G.M., Ruda M.A., Dubner R. The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain. 50:1992;331-344.
    • (1992) Pain , vol.50 , pp. 331-344
    • Ren, K.1    Hylden, J.L.2    Williams, G.M.3    Ruda, M.A.4    Dubner, R.5
  • 43
    • 0034984121 scopus 로고    scopus 로고
    • Increased spinal N-methyl-D - Aspartate receptor function after 20 h of carrageenan-induced inflammation
    • Rygh L.J., Svendsen F., Hole K., Tjolsen A. Increased spinal N-methyl-D - aspartate receptor function after 20 h of carrageenan-induced inflammation. Pain. 93:2001;15-21.
    • (2001) Pain , vol.93 , pp. 15-21
    • Rygh, L.J.1    Svendsen, F.2    Hole, K.3    Tjolsen, A.4
  • 44
    • 0025167399 scopus 로고
    • A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
    • Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 43:1990;205-218.
    • (1990) Pain , vol.43 , pp. 205-218
    • Seltzer, Z.1    Dubner, R.2    Shir, Y.3
  • 45
    • 0034615844 scopus 로고    scopus 로고
    • Differential effects of MK-801, an N-methyl-D - Aspartate non-competitive antagonist, on the dorsal horn neuron hyperactivity and hyperexcitability in neuropathic rats
    • Sotgiu M.L., Biella G. Differential effects of MK-801, an N-methyl-D - aspartate non-competitive antagonist, on the dorsal horn neuron hyperactivity and hyperexcitability in neuropathic rats. Neurosci Lett. 283:2000;153-156.
    • (2000) Neurosci Lett , vol.283 , pp. 153-156
    • Sotgiu, M.L.1    Biella, G.2
  • 46
    • 0030221060 scopus 로고    scopus 로고
    • Behavioral and electrophysiological assessment of hyperalgesia and changes in dorsal horn responses following partial sciatic nerve ligation in rats
    • Takaishi K., Eisele J.H. Jr, Carstens E. Behavioral and electrophysiological assessment of hyperalgesia and changes in dorsal horn responses following partial sciatic nerve ligation in rats. Pain. 66:1996;297-306.
    • (1996) Pain , vol.66 , pp. 297-306
    • Takaishi, K.1    Eisele J.H., Jr.2    Carstens, E.3
  • 47
    • 0027210790 scopus 로고
    • Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat
    • Tal M., Bennett G.J. Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat. Neurosci Lett. 151:1993;107-110.
    • (1993) Neurosci Lett , vol.151 , pp. 107-110
    • Tal, M.1    Bennett, G.J.2
  • 48
    • 0028064408 scopus 로고
    • Neuropathic pain sensations are differentially sensitive to dextrorphan
    • Tal M., Bennett G.J. Neuropathic pain sensations are differentially sensitive to dextrorphan. NeuroReport. 5:1994;1438-1440.
    • (1994) NeuroReport , vol.5 , pp. 1438-1440
    • Tal, M.1    Bennett, G.J.2
  • 51
    • 0031763988 scopus 로고    scopus 로고
    • Pituitary-adrenocortical responses to persistent noxious stimuli in the awake rat: Endogenous corticosterone does not reduce nociception in the formalin test
    • Taylor B.K., Akana S.F., Peterson M.A., Dallman M.F., Basbaum A.I. Pituitary-adrenocortical responses to persistent noxious stimuli in the awake rat: endogenous corticosterone does not reduce nociception in the formalin test. Endocrinology. 139:1998;2407-2413.
    • (1998) Endocrinology , vol.139 , pp. 2407-2413
    • Taylor, B.K.1    Akana, S.F.2    Peterson, M.A.3    Dallman, M.F.4    Basbaum, A.I.5
  • 52
    • 0027141312 scopus 로고
    • The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray
    • Tölle T.R., Berthele A., Zieglgansberger W., Seeburg P.H., Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J Neurosci. 12:1993;5009-5028.
    • (1993) J Neurosci , vol.12 , pp. 5009-5028
    • Tölle, T.R.1    Berthele, A.2    Zieglgansberger, W.3    Seeburg, P.H.4    Wisden, W.5
  • 53
    • 0030986006 scopus 로고    scopus 로고
    • Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats
    • Wegert S., Ossipov M.H., Nichols M.L., Bian D., Vanderah T.W., Malan T.P. Jr, Porreca F. Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats. Pain. 71:1997;57-64.
    • (1997) Pain , vol.71 , pp. 57-64
    • Wegert, S.1    Ossipov, M.H.2    Nichols, M.L.3    Bian, D.4    Vanderah, T.W.5    Malan T.P., Jr.6    Porreca, F.7
  • 55
    • 0033933764 scopus 로고    scopus 로고
    • Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-Daspartate antagonist conantokin-G: In vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies
    • Williams A.J., Dave J.R., Phillips J.B., Lin Y., McCabe R.T., Tortella F.C. Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-Daspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies. J Pharmacol Exp Ther. 294:2000;378-386.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 378-386
    • Williams, A.J.1    Dave, J.R.2    Phillips, J.B.3    Lin, Y.4    McCabe, R.T.5    Tortella, F.C.6
  • 56
    • 0021014399 scopus 로고
    • Evidence for a central component of post-injury pain hypersensitivity
    • Woolf C.J. Evidence for a central component of post-injury pain hypersensitivity. Nature. 306:1993;686-688.
    • (1993) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 57
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; Implications for the treatment of post-injury pain hypersensitivity states
    • Woolf C.J., Thompson S.W. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain. 44:1991;293-299.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.2
  • 58
    • 0026629818 scopus 로고
    • Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat
    • Yamamoto T., Yaksh T.L. Comparison of the antinociceptive effects of pre- and posttreatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology. 77:1992;757-763.
    • (1992) Anesthesiology , vol.77 , pp. 757-763
    • Yamamoto, T.1    Yaksh, T.L.2
  • 59
    • 0026588069 scopus 로고
    • Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists
    • Yamamoto T., Yaksh T.L. Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists. Pain. 49:1992;121-128.
    • (1992) Pain , vol.49 , pp. 121-128
    • Yamamoto, T.1    Yaksh, T.L.2
  • 60
    • 0032507588 scopus 로고    scopus 로고
    • Localization of glutamate receptors in dorsal horn of rat spinal cord
    • Yung K.K.L. Localization of glutamate receptors in dorsal horn of rat spinal cord. NeuroReport. 9:1998;1639-1644.
    • (1998) NeuroReport , vol.9 , pp. 1639-1644
    • Yung, K.K.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.