메뉴 건너뛰기




Volumn 37, Issue 4, 2010, Pages 451-459

Myostatin gene knockdown by myostatin-specific short interfering hairpin RNAs increases MyoD expression in C2C12 myoblasts

Author keywords

MyoD; Myostatin; RNA interference; ShRNA; SiRNA

Indexed keywords

MUS; RATTUS;

EID: 77954773184     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2009.00486     Document Type: Article
Times cited : (7)

References (49)
  • 1
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron A C, Lawler A M, Lee S J. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature, 1997, 387(6628): 83-90
    • (1997) Nature , vol.387 , Issue.6628 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 2
    • 12444297498 scopus 로고    scopus 로고
    • Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene
    • Grobet L, Pirottin D, Farnir F, et al. Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis, 2003, 35(4): 227-238
    • (2003) Genesis , vol.35 , Issue.4 , pp. 227-238
    • Grobet, L.1    Pirottin, D.2    Farnir, F.3
  • 3
    • 16944364045 scopus 로고    scopus 로고
    • A deletion in the bovine myostatin gene causes the double muscled phenotype in cattle
    • Grobet L, Martin L J R, Poncelet D, et al. A deletion in the bovine myostatin gene causes the double muscled phenotype in cattle. Nat Genet, 1997, 17(1): 71-74
    • (1997) Nat Genet , vol.17 , Issue.1 , pp. 71-74
    • Grobet, L.1    Martin, L.J.R.2    Poncelet, D.3
  • 4
    • 15644381757 scopus 로고    scopus 로고
    • Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double muscling in cattle
    • Grobet L, Poncelet D, Royo L J, et al. Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double muscling in cattle. Mamm Genome, 1998, 9(3): 210-213
    • (1998) Mamm Genome , vol.9 , Issue.3 , pp. 210-213
    • Grobet, L.1    Poncelet, D.2    Royo, L.J.3
  • 5
    • 0030818314 scopus 로고    scopus 로고
    • Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle
    • Kambadur R, Sharma M, Smith T P L, et al. Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res, 1997, 7(9): 910-915
    • (1997) Genome Res , vol.7 , Issue.9 , pp. 910-915
    • Kambadur, R.1    Sharma, M.2    Smith, T.P.L.3
  • 6
    • 0030840359 scopus 로고    scopus 로고
    • Double muscling in cattle due to mutations in the myostatin gene
    • McPherron A C, Lee S J. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci USA, 1997, 94(23): 12457-12461
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.23 , pp. 12457-12461
    • McPherron, A.C.1    Lee, S.J.2
  • 7
    • 58549100718 scopus 로고    scopus 로고
    • Associations between the 11-bp deletion in the myostatin gene and carcass quality in Angus-sired cattle
    • Gill J L, Bishop S C, McCorquodale C, et al. Associations between the 11-bp deletion in the myostatin gene and carcass quality in Angus-sired cattle. Anim Genet, 2009, 40(1): 97-100
    • (2009) Anim Genet , vol.40 , Issue.1 , pp. 97-100
    • Gill, J.L.1    Bishop, S.C.2    McCorquodale, C.3
  • 8
    • 2942735123 scopus 로고    scopus 로고
    • Myostatin mutation associated with gross muscle hypertrophy in a child
    • Schuelke M, Wagner K R, Stolz L E, et al. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med, 2004, 350(26): 2682-2688
    • (2004) N Engl J Med , vol.350 , Issue.26 , pp. 2682-2688
    • Schuelke, M.1    Wagner, K.R.2    Stolz, L.E.3
  • 9
    • 34249849694 scopus 로고    scopus 로고
    • Run, whippet, run
    • Shadan S. Run, whippet, run. Nature, 2007, 447(7142): 275
    • (2007) Nature , vol.447 , Issue.7142 , pp. 275
    • Shadan, S.1
  • 10
    • 0141615887 scopus 로고    scopus 로고
    • Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin
    • Reisz-Porszasz S, Bhasin S, Artaza J N, et al. Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin. Am J Physiol Endocrinol Metab, 2003, 285(4): E876-E888
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , Issue.4
    • Reisz-Porszasz, S.1    Bhasin, S.2    Artaza, J.N.3
  • 11
    • 9144243683 scopus 로고    scopus 로고
    • Activation of latent myostatin by the BMP-l/tolloid family of metalloproteinases
    • Wolfman N M, McPherron A C, Pappano W N, et al. Activation of latent myostatin by the BMP-l/tolloid family of metalloproteinases. Proc Natl Acad Sci USA, 2003, 100(26): 15842-15846
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.26 , pp. 15842-15846
    • Wolfman, N.M.1    McPherron, A.C.2    Pappano, W.N.3
  • 12
    • 41149152962 scopus 로고    scopus 로고
    • Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice
    • Qiao C, Li J, Jiang J, et al. Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice. Hum Gene Ther, 2008, 19 (3): 241-254
    • (2008) Hum Gene Ther , vol.19 , Issue.3 , pp. 241-254
    • Qiao, C.1    Li, J.2    Jiang, J.3
  • 13
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
    • DOI 10.1038/35888
    • Fire A, Xu S, Montgomery M K, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391(6669): 806-811 (Pubitemid 28099681)
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 14
    • 38549170471 scopus 로고    scopus 로고
    • Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice
    • Liu C M, Yang Z, Liu C W, et al. Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice. Gene Ther, 2008, 15(3): 155-160
    • (2008) Gene Ther , vol.15 , Issue.3 , pp. 155-160
    • Liu, C.M.1    Yang, Z.2    Liu, C.W.3
  • 15
    • 58149471229 scopus 로고    scopus 로고
    • Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle
    • Amirouche A, Durieux A C, Freyssenet D, et al. Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle. Endocrinology, 2009, 150(1): 286-294
    • (2009) Endocrinology , vol.150 , Issue.1 , pp. 286-294
    • Amirouche, A.1    Durieux, A.C.2    Freyssenet, D.3
  • 16
    • 66749188280 scopus 로고    scopus 로고
    • Myostatin reduces AKT/TORCl/p70S6K signaling, inhibiting myoblast differentiation and myotube size
    • Trendelenburg A U, Meyer A, Rohner D, et al. Myostatin reduces AKT/TORCl/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am J Physiol Cell Physiol, 2009, 296 (6): C1258-1270
    • (2009) Am J Physiol Cell Physiol , vol.296 , Issue.6
    • Trendelenburg, A.U.1    Meyer, A.2    Rohner, D.3
  • 17
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee S J. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol, 2004, 20: 61-86
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 18
    • 41549084155 scopus 로고    scopus 로고
    • Transforming growth factor-beta and myostatin signaling in skeletal muscle
    • Kollias H D, McDermott J C. Transforming growth factor-beta and myostatin signaling in skeletal muscle. J Appl Physiol, 2008, 104(3): 579-587
    • (2008) J Appl Physiol , vol.104 , Issue.3 , pp. 579-587
    • Kollias, H.D.1    McDermott, J.C.2
  • 19
    • 0036437330 scopus 로고    scopus 로고
    • Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos
    • Pownall M E, Gustafsson M K, Jr Emerson C P. Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. Annu Rev Cell Dev Biol, 2002, 18: 747-783
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 747-783
    • Pownall, M.E.1    Gustafsson Jr. M, K.2    Emerson, C.P.3
  • 20
    • 0032437107 scopus 로고    scopus 로고
    • Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
    • Black B L, Olson E N. Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu Rev Cell Dev Biol, 1998, 14: 167-196
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 167-196
    • Black, B.L.1    Olson, E.N.2
  • 21
    • 0036087344 scopus 로고    scopus 로고
    • Myostatin is an inhibitor of myogenic differentiation
    • Rios R, Carneiro I, Arce V M, et al. Myostatin is an inhibitor of myogenic differentiation. Am J Physiol Cell Physiol, 2002, 282(5): C993-C999
    • (2002) Am J Physiol Cell Physiol , vol.282 , Issue.5
    • Rios, R.1    Carneiro, I.2    Arce, V.M.3
  • 22
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S M, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 2001, 411(6836): 494-498
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 23
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp T R, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296(5567): 550-553
    • (2002) Science , vol.296 , Issue.5567 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 24
    • 47549101861 scopus 로고    scopus 로고
    • Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass
    • Kinouchi N, Ohsawa Y, Ishimaru N, et al. Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass. Gene Ther, 2008, 15 (15): 1126-1130
    • (2008) Gene Ther , vol.15 , Issue.15 , pp. 1126-1130
    • Kinouchi, N.1    Ohsawa, Y.2    Ishimaru, N.3
  • 25
    • 33749249252 scopus 로고    scopus 로고
    • Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass
    • Magee T R, Artaza J N, Ferrini M G, et al. Myostatin short interfering hairpin RNA gene transfer increases skeletal muscle mass. J Gene Med, 2006, 8(9): 1171-1181
    • (2006) J Gene Med , vol.8 , Issue.9 , pp. 1171-1181
    • Magee, T.R.1    Artaza, J.N.2    Ferrini, M.G.3
  • 26
    • 24944552084 scopus 로고    scopus 로고
    • Myostatin gene silenced by RNAi show a zebrafish giant phenotype
    • Acosta J, Carpio Y, Borroto I, et al. Myostatin gene silenced by RNAi show a zebrafish giant phenotype. J Biotechnol, 2005, 119(4): 324-331
    • (2005) J Biotechnol , vol.119 , Issue.4 , pp. 324-331
    • Acosta, J.1    Carpio, Y.2    Borroto, I.3
  • 27
    • 0037462964 scopus 로고    scopus 로고
    • Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
    • Whittemore L A, Song K, Li X, et al. Inhibition of myostatin in adult mice increases skeletal muscle mass and strength. Biochem Biophys Res Commun, 2003, 300(4): 965-971
    • (2003) Biochem Biophys Res Commun , vol.300 , Issue.4 , pp. 965-971
    • Whittemore, L.A.1    Song, K.2    Li, X.3
  • 28
    • 0037191752 scopus 로고    scopus 로고
    • Functional improvement of dystrophic muscle by myostatin blockade
    • Bogdanovich S, Krag T O, Barton E R, et al. Functional improvement of dystrophic muscle by myostatin blockade. Nature 2002, 420(6914): 418-421
    • (2002) Nature , vol.420 , Issue.6914 , pp. 418-421
    • Bogdanovich, S.1    Krag, T.O.2    Barton, E.R.3
  • 29
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G J. RNA interference. Nature, 2002, 418(6894): 244-251
    • (2002) Nature , vol.418 , Issue.6894 , pp. 244-251
    • Hannon, G.J.1
  • 30
    • 33746845652 scopus 로고    scopus 로고
    • Myostatin expression in porcine tissues: Tissue specificity and developmental and postnatal regulation
    • Ji S, Losinski R L, Cornelius S G, et al. Myostatin expression in porcine tissues: tissue specificity and developmental and postnatal regulation. Am J Physiol Regul Integr Comp Physiol, 1998, 275 (4pt2): R1265-R1273
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.275 , Issue.4 PART 2
    • Ji, S.1    Losinski, R.L.2    Cornelius, S.G.3
  • 31
    • 0033006969 scopus 로고    scopus 로고
    • Myostatin, a transforming growth factor-p superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct
    • Sharma M, Kambadur R, Matthews K G, et al. Myostatin, a transforming growth factor-p superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct. J Cell Physiol, 1999, 180(1): 1-9
    • (1999) J Cell Physiol , vol.180 , Issue.1 , pp. 1-9
    • Sharma, M.1    Kambadur, R.2    Matthews, K.G.3
  • 32
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • Thomas M, Langley B, Berry C, et al. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J Biol Chem, 2000, 275 (51): 40235-40243
    • (2000) J Biol Chem , vol.275 , Issue.51 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3
  • 34
    • 18744396428 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle mass: Implications for muscle degenerative diseases
    • Tobin J F, Celeste A J. Myostatin, a negative regulator of muscle mass: implications for muscle degenerative diseases. Curr Opin Pharmacol, 2005, 5(3): 328-332
    • (2005) Curr Opin Pharmacol , vol.5 , Issue.3 , pp. 328-332
    • Tobin, J.F.1    Celeste, A.J.2
  • 35
    • 13444293017 scopus 로고    scopus 로고
    • The function of myostatin and strategies of myostatin blockade-new hope for therapies aimed at promoting growth of skeletal muscle
    • Patel K, Amthor H. The function of myostatin and strategies of myostatin blockade-new hope for therapies aimed at promoting growth of skeletal muscle. Neuromuscul Disord, 2005, 15(2): 117-126
    • (2005) Neuromuscul Disord , vol.15 , Issue.2 , pp. 117-126
    • Patel, K.1    Amthor, H.2
  • 36
    • 0035983150 scopus 로고    scopus 로고
    • Muscle-related traits in cattle: The role of the myostatin gene in the South Devon breed
    • Wiener P, Smith J A, Lewis A M, et al. Muscle-related traits in cattle: The role of the myostatin gene in the South Devon breed. Genet Set Evol, 2002, 34(2): 221-232
    • (2002) Genet Set Evol , vol.34 , Issue.2 , pp. 221-232
    • Wiener, P.1    Smith, J.A.2    Lewis, A.M.3
  • 37
    • 0005325783 scopus 로고
    • The major gene of muscular hypertrophy in the Belgian Blue cattle breed
    • Owen J B, Axford R F E. Bangor, UK: CAB International
    • Hanset R. The major gene of muscular hypertrophy in the Belgian Blue cattle breed//Owen J B, Axford R F E. Breeding for Disease Resistance in Farm Animals. Bangor, UK: CAB International, 1991: 467-478
    • (1991) Breeding for Disease Resistance in Farm Animals , pp. 467-478
    • Hanset, R.1
  • 39
    • 24944560377 scopus 로고    scopus 로고
    • A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
    • Stegmeier F, Hu G, Rickles R J, et al. A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc Natl Acad Sci USA, 2005, 102(37): 13212-13217
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.37 , pp. 13212-13217
    • Stegmeier, F.1    Hu, G.2    Rickles, R.J.3
  • 40
    • 26644467465 scopus 로고    scopus 로고
    • Single copy shRNA configuration for ubiquitous gene knockdown in mice
    • Seibler J, Kuter-Luks B, Kern H, et al. Single copy shRNA configuration for ubiquitous gene knockdown in mice. Nucleic Acids Res, 2005, 33(7): e67
    • (2005) Nucleic Acids Res , vol.33 , Issue.7
    • Seibler, J.1    Kuter-Luks, B.2    Kern, H.3
  • 41
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison P J, Caudy A A, Bernstein E, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev, 2002, 16(8): 948-958
    • (2002) Genes Dev , vol.16 , Issue.8 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3
  • 43
    • 0036653097 scopus 로고    scopus 로고
    • RNA interference: The new somatic cell genetics?
    • Paddison P J, Hannon G J. RNA interference: the new somatic cell genetics?. Cancer Cell, 2002, 2(1): 17-23
    • (2002) Cancer Cell , vol.2 , Issue.1 , pp. 17-23
    • Paddison, P.J.1    Hannon, G.J.2
  • 44
    • 13844280638 scopus 로고    scopus 로고
    • Synthetic shRNAs as potent RNAi triggers
    • Siolas D, Lerner C, Burchard J, et al. Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol, 2004, 23(2): 227-231
    • (2004) Nat Biotechnol , vol.23 , Issue.2 , pp. 227-231
    • Siolas, D.1    Lerner, C.2    Burchard, J.3
  • 45
    • 0037312978 scopus 로고    scopus 로고
    • Germline transmission of RNAi in mice
    • Carmell M A, Zhang L, Conklin D S, et al. Germline transmission of RNAi in mice. Nat Struct Biol, 2003, 10(2): 91-92
    • (2003) Nat Struct Biol , vol.10 , Issue.2 , pp. 91-92
    • Carmell, M.A.1    Zhang, L.2    Conklin, D.S.3
  • 46
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson D A, Dillon C P, Kwiatkowski A V, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet, 2003, 33(3): 401-406
    • (2003) Nat Genet , vol.33 , Issue.3 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 47
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G, Singer O, Ikawa M, et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA, 2003, 100(4): 1844-1848
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.4 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3
  • 48
    • 2442584612 scopus 로고    scopus 로고
    • CRE recombinase-inducible RNA interference mediated by lentiviral vectors
    • Tiscornia G, Tergaonkar V, Galimi F, et al. CRE recombinase-inducible RNA interference mediated by lentiviral vectors. Proc Natl Acad Sci USA, 2004, 101(19): 7347-7351
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.19 , pp. 7347-7351
    • Tiscornia, G.1    Tergaonkar, V.2    Galimi, F.3
  • 49
    • 33645762032 scopus 로고    scopus 로고
    • Suppression of prion protein in livestock by RNA interference
    • Michael C G, Charles R L, Michelle A C, et al. Suppression of prion protein in livestock by RNA interference. Proc Natl Acad Sci USA, 2006, 103(14): 5285-5290
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.14 , pp. 5285-5290
    • Michael, C.G.1    Charles, R.L.2    Michelle, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.