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Volumn 10, Issue , 2010, Pages

Troglitazone suppresses telomerase activity independently of PPARγ in estrogen-receptor negative breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SHORT HAIRPIN RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TROGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; CHROMAN DERIVATIVE; ESR1 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; SMALL INTERFERING RNA; TERT PROTEIN, HUMAN; TUMOR MARKER;

EID: 77954763598     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-390     Document Type: Article
Times cited : (20)

References (58)
  • 1
    • 55849134768 scopus 로고    scopus 로고
    • Canadian Cancer Statistics
    • Canadian Cancer Society, National Cancer Institute of Canada, Statistics Canada PTCR, Canada PHAo
    • Canadian Cancer Society, National Cancer Institute of Canada, Statistics Canada PTCR, Canada PHAo Canadian Cancer Statistics. Canadian Cancer Statistics 2008, Canadian Cancer Society, National Cancer Institute of Canada, Statistics Canada PTCR, Canada PHAo.
    • (2008) Canadian Cancer Statistics
  • 2
    • 33846266252 scopus 로고    scopus 로고
    • Prognostic markers in triple-negative breast cancer
    • 10.1002/cncr.22381, 17146782
    • Rakha EA, El-Sayed ME, Green AR, Lee AH, Robertson JF, Ellis IO. Prognostic markers in triple-negative breast cancer. Cancer 2007, 109(1):25-32. 10.1002/cncr.22381, 17146782.
    • (2007) Cancer , vol.109 , Issue.1 , pp. 25-32
    • Rakha, E.A.1    El-Sayed, M.E.2    Green, A.R.3    Lee, A.H.4    Robertson, J.F.5    Ellis, I.O.6
  • 4
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • 10.1038/nrc2275, 18256617
    • Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008, 8(3):167-179. 10.1038/nrc2275, 18256617.
    • (2008) Nat Rev Cancer , vol.8 , Issue.3 , pp. 167-179
    • Harley, C.B.1
  • 5
    • 0031887947 scopus 로고    scopus 로고
    • Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers
    • Carey LA, Hedican CA, Henderson GS, Umbricht CB, Dome JS, Varon D, Sukumar S. Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers. Clin Cancer Res 1998, 4(2):435-440.
    • (1998) Clin Cancer Res , vol.4 , Issue.2 , pp. 435-440
    • Carey, L.A.1    Hedican, C.A.2    Henderson, G.S.3    Umbricht, C.B.4    Dome, J.S.5    Varon, D.6    Sukumar, S.7
  • 7
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • 10.1016/S0959-8049(97)00062-2, 9282118
    • Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33(5):787-791. 10.1016/S0959-8049(97)00062-2, 9282118.
    • (1997) Eur J Cancer , vol.33 , Issue.5 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 8
    • 34147095342 scopus 로고    scopus 로고
    • Protein composition of catalytically active human telomerase from immortal cells
    • 10.1126/science.1138596, 17395830
    • Cohen SB, Graham ME, Lovrecz GO, Bache N, Robinson PJ, Reddel RR. Protein composition of catalytically active human telomerase from immortal cells. Science 2007, 315(5820):1850-1853. 10.1126/science.1138596, 17395830.
    • (2007) Science , vol.315 , Issue.5820 , pp. 1850-1853
    • Cohen, S.B.1    Graham, M.E.2    Lovrecz, G.O.3    Bache, N.4    Robinson, P.J.5    Reddel, R.R.6
  • 10
    • 0027191040 scopus 로고
    • CDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
    • 10.1021/bi00072a015, 7684926
    • Sher T, Yi HF, McBride OW, Gonzalez FJ. cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry 1993, 32(21):5598-5604. 10.1021/bi00072a015, 7684926.
    • (1993) Biochemistry , vol.32 , Issue.21 , pp. 5598-5604
    • Sher, T.1    Yi, H.F.2    McBride, O.W.3    Gonzalez, F.J.4
  • 11
    • 0026785388 scopus 로고
    • Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
    • 10.1210/me.6.10.1634, 1333051
    • Schmidt A, Endo N, Rutledge SJ, Vogel R, Shinar D, Rodan GA. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol 1992, 6(10):1634-1641. 10.1210/me.6.10.1634, 1333051.
    • (1992) Mol Endocrinol , vol.6 , Issue.10 , pp. 1634-1641
    • Schmidt, A.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Shinar, D.5    Rodan, G.A.6
  • 12
    • 0030590074 scopus 로고    scopus 로고
    • Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2
    • 10.1006/bbrc.1996.1044, 8702406
    • Elbrecht A, Chen Y, Cullinan CA, Hayes N, Leibowitz M, Moller DE, Berger J. Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem Biophys Res Commun 1996, 224(2):431-437. 10.1006/bbrc.1996.1044, 8702406.
    • (1996) Biochem Biophys Res Commun , vol.224 , Issue.2 , pp. 431-437
    • Elbrecht, A.1    Chen, Y.2    Cullinan, C.A.3    Hayes, N.4    Leibowitz, M.5    Moller, D.E.6    Berger, J.7
  • 13
    • 34247558604 scopus 로고    scopus 로고
    • Synergy between PPARgamma ligands and platinum-based drugs in cancer
    • 10.1016/j.ccr.2007.02.025, 2564847, 17482130
    • Girnun GD, Naseri E, Vafai SB, Qu L, Szwaya JD, Bronson R, Alberta JA, Spiegelman BM. Synergy between PPARgamma ligands and platinum-based drugs in cancer. Cancer Cell 2007, 11(5):395-406. 10.1016/j.ccr.2007.02.025, 2564847, 17482130.
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 395-406
    • Girnun, G.D.1    Naseri, E.2    Vafai, S.B.3    Qu, L.4    Szwaya, J.D.5    Bronson, R.6    Alberta, J.A.7    Spiegelman, B.M.8
  • 14
    • 0343855442 scopus 로고    scopus 로고
    • Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer
    • 10.1073/pnas.180329197, 27136, 10984506
    • Mueller E, Smith M, Sarraf P, Kroll T, Aiyer A, Kaufman DS, Oh W, Demetri G, Figg WD, Zhou XP, et al. Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. Proc Natl Acad Sci USA 2000, 97(20):10990-10995. 10.1073/pnas.180329197, 27136, 10984506.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.20 , pp. 10990-10995
    • Mueller, E.1    Smith, M.2    Sarraf, P.3    Kroll, T.4    Aiyer, A.5    Kaufman, D.S.6    Oh, W.7    Demetri, G.8    Figg, W.D.9    Zhou, X.P.10
  • 16
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • 10.1016/j.cell.2005.11.026, 16360030
    • Lehrke M, Lazar MA. The many faces of PPARgamma. Cell 2005, 123(6):993-999. 10.1016/j.cell.2005.11.026, 16360030.
    • (2005) Cell , vol.123 , Issue.6 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 17
    • 33947324058 scopus 로고    scopus 로고
    • PPARgamma activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: the importance of interplay with TGFbeta signalling
    • 10.1111/j.1582-4934.2007.00003.x, 17367502
    • Jarrar MH, Baranova A. PPARgamma activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: the importance of interplay with TGFbeta signalling. J Cell Mol Med 2007, 11(1):71-87. 10.1111/j.1582-4934.2007.00003.x, 17367502.
    • (2007) J Cell Mol Med , vol.11 , Issue.1 , pp. 71-87
    • Jarrar, M.H.1    Baranova, A.2
  • 18
    • 0035964872 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists
    • 10.1006/bbrc.2001.5640, 11563856
    • Inoue K, Kawahito Y, Tsubouchi Y, Kohno M, Yoshimura R, Yoshikawa T, Sano H. Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists. Biochem Biophys Res Commun 2001, 287(3):727-732. 10.1006/bbrc.2001.5640, 11563856.
    • (2001) Biochem Biophys Res Commun , vol.287 , Issue.3 , pp. 727-732
    • Inoue, K.1    Kawahito, Y.2    Tsubouchi, Y.3    Kohno, M.4    Yoshimura, R.5    Yoshikawa, T.6    Sano, H.7
  • 21
    • 0033741281 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists
    • 10.1054/bjoc.2000.1457, 2408786, 11044367
    • Sato H, Ishihara S, Kawashima K, Moriyama N, Suetsugu H, Kazumori H, Okuyama T, Rumi MA, Fukuda R, Nagasue N, et al. Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. Br J Cancer 2000, 83(10):1394-1400. 10.1054/bjoc.2000.1457, 2408786, 11044367.
    • (2000) Br J Cancer , vol.83 , Issue.10 , pp. 1394-1400
    • Sato, H.1    Ishihara, S.2    Kawashima, K.3    Moriyama, N.4    Suetsugu, H.5    Kazumori, H.6    Okuyama, T.7    Rumi, M.A.8    Fukuda, R.9    Nagasue, N.10
  • 22
    • 12644265334 scopus 로고    scopus 로고
    • Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor
    • 10.1073/pnas.94.1.237, 19300, 8990192
    • Tontonoz P, Singer S, Forman BM, Sarraf P, Fletcher JA, Fletcher CD, Brun RP, Mueller E, Altiok S, Oppenheim H, et al. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proc Natl Acad Sci USA 1997, 94(1):237-241. 10.1073/pnas.94.1.237, 19300, 8990192.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.1 , pp. 237-241
    • Tontonoz, P.1    Singer, S.2    Forman, B.M.3    Sarraf, P.4    Fletcher, J.A.5    Fletcher, C.D.6    Brun, R.P.7    Mueller, E.8    Altiok, S.9    Oppenheim, H.10
  • 23
    • 33745113772 scopus 로고    scopus 로고
    • Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones
    • 10.1677/erc.1.01182, 16728570
    • Weng JR, Chen CY, Pinzone JJ, Ringel MD, Chen CS. Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones. Endocr Relat Cancer 2006, 13(2):401-413. 10.1677/erc.1.01182, 16728570.
    • (2006) Endocr Relat Cancer , vol.13 , Issue.2 , pp. 401-413
    • Weng, J.R.1    Chen, C.Y.2    Pinzone, J.J.3    Ringel, M.D.4    Chen, C.S.5
  • 24
    • 0037899628 scopus 로고    scopus 로고
    • Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase II study
    • 10.1023/A:1024038127156, 12846423
    • Burstein HJ, Demetri GD, Mueller E, Sarraf P, Spiegelman BM, Winer EP. Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase II study. Breast Cancer Res Treat 2003, 79(3):391-397. 10.1023/A:1024038127156, 12846423.
    • (2003) Breast Cancer Res Treat , vol.79 , Issue.3 , pp. 391-397
    • Burstein, H.J.1    Demetri, G.D.2    Mueller, E.3    Sarraf, P.4    Spiegelman, B.M.5    Winer, E.P.6
  • 27
    • 33749176815 scopus 로고    scopus 로고
    • Functional genomics of PPAR-gamma in human immunomodulatory cells
    • 10.1007/s11010-006-9169-8, 16633734
    • Kaul D, Anand PK, Khanna A. Functional genomics of PPAR-gamma in human immunomodulatory cells. Mol Cell Biochem 2006, 290(1-2):211-215. 10.1007/s11010-006-9169-8, 16633734.
    • (2006) Mol Cell Biochem , vol.290 , Issue.1-2 , pp. 211-215
    • Kaul, D.1    Anand, P.K.2    Khanna, A.3
  • 28
    • 33646149159 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma suppresses telomerase activity in vascular smooth muscle cells
    • 10.1161/01.RES.0000218271.93076.c3, 16556873
    • Ogawa D, Nomiyama T, Nakamachi T, Heywood EB, Stone JF, Berger JP, Law RE, Bruemmer D. Activation of peroxisome proliferator-activated receptor gamma suppresses telomerase activity in vascular smooth muscle cells. Circ Res 2006, 98(7):e50-59. 10.1161/01.RES.0000218271.93076.c3, 16556873.
    • (2006) Circ Res , vol.98 , Issue.7
    • Ogawa, D.1    Nomiyama, T.2    Nakamachi, T.3    Heywood, E.B.4    Stone, J.F.5    Berger, J.P.6    Law, R.E.7    Bruemmer, D.8
  • 29
    • 2442657794 scopus 로고    scopus 로고
    • The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines
    • 10.1124/jpet.103.063438, 14988421
    • Strakova N, Ehrmann J, Dzubak P, Bouchal J, Kolar Z. The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines. J Pharmacol Exp Ther 2004, 309(3):1239-1247. 10.1124/jpet.103.063438, 14988421.
    • (2004) J Pharmacol Exp Ther , vol.309 , Issue.3 , pp. 1239-1247
    • Strakova, N.1    Ehrmann, J.2    Dzubak, P.3    Bouchal, J.4    Kolar, Z.5
  • 30
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • 110254, 9765382
    • Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. A third-generation lentivirus vector with a conditional packaging system. J Virol 1998, 72(11):8463-8471. 110254, 9765382.
    • (1998) J Virol , vol.72 , Issue.11 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4    Nguyen, M.5    Trono, D.6    Naldini, L.7
  • 31
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • 10.1073/pnas.93.21.11382, 38066, 8876144
    • Naldini L, Blomer U, Gage FH, Trono D, Verma IM. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA 1996, 93(21):11382-11388. 10.1073/pnas.93.21.11382, 38066, 8876144.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.21 , pp. 11382-11388
    • Naldini, L.1    Blomer, U.2    Gage, F.H.3    Trono, D.4    Verma, I.M.5
  • 33
    • 34047274821 scopus 로고    scopus 로고
    • 15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain
    • 10.1158/0008-5472.CAN-06-3043, 17363578
    • Kim HJ, Kim JY, Meng Z, Wang LH, Liu F, Conrads TP, Burke TR, Veenstra TD, Farrar WL. 15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain. Cancer Res 2007, 67(6):2595-2602. 10.1158/0008-5472.CAN-06-3043, 17363578.
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2595-2602
    • Kim, H.J.1    Kim, J.Y.2    Meng, Z.3    Wang, L.H.4    Liu, F.5    Conrads, T.P.6    Burke, T.R.7    Veenstra, T.D.8    Farrar, W.L.9
  • 34
    • 0034695479 scopus 로고    scopus 로고
    • A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation
    • 10.1074/jbc.275.3.1873, 10636887
    • Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Hiramatsu R, Serhan CN, Spiegelman BM. A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation. J Biol Chem 2000, 275(3):1873-1877. 10.1074/jbc.275.3.1873, 10636887.
    • (2000) J Biol Chem , vol.275 , Issue.3 , pp. 1873-1877
    • Wright, H.M.1    Clish, C.B.2    Mikami, T.3    Hauser, S.4    Yanagi, K.5    Hiramatsu, R.6    Serhan, C.N.7    Spiegelman, B.M.8
  • 35
    • 0031593138 scopus 로고    scopus 로고
    • The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines
    • 10.1016/S0300-483X(97)00151-0, 9482120
    • Malich G, Markovic B, Winder C. The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines. Toxicology 1997, 124(3):179-192. 10.1016/S0300-483X(97)00151-0, 9482120.
    • (1997) Toxicology , vol.124 , Issue.3 , pp. 179-192
    • Malich, G.1    Markovic, B.2    Winder, C.3
  • 36
    • 34250901928 scopus 로고    scopus 로고
    • Effects of thiazolidinediones on differentiation, proliferation, and apoptosis
    • 10.1158/1541-7786.MCR-06-0278, 17579114
    • Chou FS, Wang PS, Kulp S, Pinzone JJ. Effects of thiazolidinediones on differentiation, proliferation, and apoptosis. Mol Cancer Res 2007, 5(6):523-530. 10.1158/1541-7786.MCR-06-0278, 17579114.
    • (2007) Mol Cancer Res , vol.5 , Issue.6 , pp. 523-530
    • Chou, F.S.1    Wang, P.S.2    Kulp, S.3    Pinzone, J.J.4
  • 38
    • 38349150862 scopus 로고    scopus 로고
    • STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells
    • Nakatake M, Kakiuchi Y, Sasaki N, Murakami-Murofushi K, Yamada O. STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells. Cell Cycle 2007, 6(12):1496-1501.
    • (2007) Cell Cycle , vol.6 , Issue.12 , pp. 1496-1501
    • Nakatake, M.1    Kakiuchi, Y.2    Sasaki, N.3    Murakami-Murofushi, K.4    Yamada, O.5
  • 39
    • 0028208912 scopus 로고
    • Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells
    • 10.1126/science.8290962, 8290962
    • Zou Z, Anisowicz A, Hendrix MJ, Thor A, Neveu M, Sheng S, Rafidi K, Seftor E, Sager R. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science 1994, 263(5146):526-529. 10.1126/science.8290962, 8290962.
    • (1994) Science , vol.263 , Issue.5146 , pp. 526-529
    • Zou, Z.1    Anisowicz, A.2    Hendrix, M.J.3    Thor, A.4    Neveu, M.5    Sheng, S.6    Rafidi, K.7    Seftor, E.8    Sager, R.9
  • 40
    • 20144386127 scopus 로고    scopus 로고
    • Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    • 10.1073/pnas.0409462102, 548329, 15701700
    • Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T, Dai H, He YD, van't Veer LJ, Bartelink H, et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA 2005, 102(10):3738-3743. 10.1073/pnas.0409462102, 548329, 15701700.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.10 , pp. 3738-3743
    • Chang, H.Y.1    Nuyten, D.S.2    Sneddon, J.B.3    Hastie, T.4    Tibshirani, R.5    Sorlie, T.6    Dai, H.7    He, Y.D.8    van't Veer, L.J.9    Bartelink, H.10
  • 41
    • 0037660837 scopus 로고    scopus 로고
    • H-ras dependent estrogenic effects of epidermal growth factor in the estrogen-independent breast cancer cell line MDA-MB-231
    • 10.1023/A:1024502107690, 12908818
    • Treeck O, Weber A, Boester M, Porz S, Frey N, Diedrich K, Ortmann O. H-ras dependent estrogenic effects of epidermal growth factor in the estrogen-independent breast cancer cell line MDA-MB-231. Breast Cancer Res Treat 2003, 80(2):155-162. 10.1023/A:1024502107690, 12908818.
    • (2003) Breast Cancer Res Treat , vol.80 , Issue.2 , pp. 155-162
    • Treeck, O.1    Weber, A.2    Boester, M.3    Porz, S.4    Frey, N.5    Diedrich, K.6    Ortmann, O.7
  • 42
    • 68649093475 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone--induced apoptosis in leukemia k562 cells and its mechanisms of action
    • 10.1177/1091581809335312, 19482836
    • Liu JJ, Hu T, Wu XY, Wang CZ, Xu Y, Zhang Y, Xiao RZ, Lin DJ, Huang RW, Liu Q. Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone--induced apoptosis in leukemia k562 cells and its mechanisms of action. Int J Toxicol 2009, 28(2):123-131. 10.1177/1091581809335312, 19482836.
    • (2009) Int J Toxicol , vol.28 , Issue.2 , pp. 123-131
    • Liu, J.J.1    Hu, T.2    Wu, X.Y.3    Wang, C.Z.4    Xu, Y.5    Zhang, Y.6    Xiao, R.Z.7    Lin, D.J.8    Huang, R.W.9    Liu, Q.10
  • 43
    • 3843145143 scopus 로고    scopus 로고
    • Prolactin acts as a potent survival factor for human breast cancer cell lines
    • 2409804, 15213724
    • Perks CM, Keith AJ, Goodhew KL, Savage PB, Winters ZE, Holly JM. Prolactin acts as a potent survival factor for human breast cancer cell lines. Br J Cancer 2004, 91(2):305-311. 2409804, 15213724.
    • (2004) Br J Cancer , vol.91 , Issue.2 , pp. 305-311
    • Perks, C.M.1    Keith, A.J.2    Goodhew, K.L.3    Savage, P.B.4    Winters, Z.E.5    Holly, J.M.6
  • 44
    • 0035990751 scopus 로고    scopus 로고
    • Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells
    • 10.1023/A:1016114026769, 12186376
    • Elstner E, Williamson EA, Zang C, Fritz J, Heber D, Fenner M, Possinger K, Koeffler HP. Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells. Breast Cancer Res Treat 2002, 74(2):155-165. 10.1023/A:1016114026769, 12186376.
    • (2002) Breast Cancer Res Treat , vol.74 , Issue.2 , pp. 155-165
    • Elstner, E.1    Williamson, E.A.2    Zang, C.3    Fritz, J.4    Heber, D.5    Fenner, M.6    Possinger, K.7    Koeffler, H.P.8
  • 45
    • 0037361266 scopus 로고    scopus 로고
    • The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells
    • 10.1023/A:1022978608125, 12725418
    • Yee LD, Guo Y, Bradbury J, Suster S, Clinton SK, Seewaldt VL. The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. Breast Cancer Res Treat 2003, 78(2):179-192. 10.1023/A:1022978608125, 12725418.
    • (2003) Breast Cancer Res Treat , vol.78 , Issue.2 , pp. 179-192
    • Yee, L.D.1    Guo, Y.2    Bradbury, J.3    Suster, S.4    Clinton, S.K.5    Seewaldt, V.L.6
  • 46
    • 33748643227 scopus 로고    scopus 로고
    • Telomerase activity, estrogen receptors (alpha, beta), Bcl-2 expression in human breast cancer and treatment response
    • 10.1186/1471-2407-6-206, 1562436, 16911782
    • Murillo-Ortiz B, Astudillo-De la Vega H, Castillo-Medina S, Malacara JM, Benitez-Bribiesca L. Telomerase activity, estrogen receptors (alpha, beta), Bcl-2 expression in human breast cancer and treatment response. BMC Cancer 2006, 6:206. 10.1186/1471-2407-6-206, 1562436, 16911782.
    • (2006) BMC Cancer , vol.6 , pp. 206
    • Murillo-Ortiz, B.1    Astudillo-De la Vega, H.2    Castillo-Medina, S.3    Malacara, J.M.4    Benitez-Bribiesca, L.5
  • 48
    • 0034142386 scopus 로고    scopus 로고
    • Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
    • 10.1093/nar/28.3.669, 102554, 10637317
    • Kyo S, Takakura M, Taira T, Kanaya T, Itoh H, Yutsudo M, Ariga H, Inoue M. Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucleic Acids Res 2000, 28(3):669-677. 10.1093/nar/28.3.669, 102554, 10637317.
    • (2000) Nucleic Acids Res , vol.28 , Issue.3 , pp. 669-677
    • Kyo, S.1    Takakura, M.2    Taira, T.3    Kanaya, T.4    Itoh, H.5    Yutsudo, M.6    Ariga, H.7    Inoue, M.8
  • 49
    • 6044243631 scopus 로고    scopus 로고
    • Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines
    • 10.1158/1078-0432.CCR-04-0879, 15501982
    • Turturro F, Friday E, Fowler R, Surie D, Welbourne T. Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines. Clin Cancer Res 2004, 10(20):7022-7030. 10.1158/1078-0432.CCR-04-0879, 15501982.
    • (2004) Clin Cancer Res , vol.10 , Issue.20 , pp. 7022-7030
    • Turturro, F.1    Friday, E.2    Fowler, R.3    Surie, D.4    Welbourne, T.5
  • 50
    • 77957719908 scopus 로고    scopus 로고
    • New troglitazone derivatives devoid of PPARgamma agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines
    • Colin C, Salamone S, Grillier-Vuissoz I, Boisbrun M, Kuntz S, Lecomte J, Chapleur Y, Flament S. New troglitazone derivatives devoid of PPARgamma agonist activity display an increased antiproliferative effect in both hormone-dependent and hormone-independent breast cancer cell lines. Breast Cancer Res Treat 2010,
    • (2010) Breast Cancer Res Treat
    • Colin, C.1    Salamone, S.2    Grillier-Vuissoz, I.3    Boisbrun, M.4    Kuntz, S.5    Lecomte, J.6    Chapleur, Y.7    Flament, S.8
  • 51
    • 34548638527 scopus 로고    scopus 로고
    • Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells
    • 10.1016/j.yexcr.2007.06.028, 17706193
    • Kondoh K, Tsuji N, Asanuma K, Kobayashi D, Watanabe N. Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells. Exp Cell Res 2007, 313(16):3486-96. 10.1016/j.yexcr.2007.06.028, 17706193.
    • (2007) Exp Cell Res , vol.313 , Issue.16 , pp. 3486-3496
    • Kondoh, K.1    Tsuji, N.2    Asanuma, K.3    Kobayashi, D.4    Watanabe, N.5
  • 52
    • 33947246971 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists cause growth arrest and apoptosis in human ovarian carcinoma cell lines
    • 10.1111/j.1525-1438.2006.00866.x, 17316361
    • Yang YC, Tsao YP, Ho TC, Choung IP. Peroxisome proliferator-activated receptor-gamma agonists cause growth arrest and apoptosis in human ovarian carcinoma cell lines. Int J Gynecol Cancer 2007, 17(2):418-425. 10.1111/j.1525-1438.2006.00866.x, 17316361.
    • (2007) Int J Gynecol Cancer , vol.17 , Issue.2 , pp. 418-425
    • Yang, Y.C.1    Tsao, Y.P.2    Ho, T.C.3    Choung, I.P.4
  • 53
    • 33747383912 scopus 로고    scopus 로고
    • Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin
    • 10.1007/s10495-006-8896-3, 16820965
    • Schultze K, Bock B, Eckert A, Oevermann L, Ramacher D, Wiestler O, Roth W. Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis 2006, 11(9):1503-1512. 10.1007/s10495-006-8896-3, 16820965.
    • (2006) Apoptosis , vol.11 , Issue.9 , pp. 1503-1512
    • Schultze, K.1    Bock, B.2    Eckert, A.3    Oevermann, L.4    Ramacher, D.5    Wiestler, O.6    Roth, W.7
  • 54
    • 13944280963 scopus 로고    scopus 로고
    • Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma
    • 10.1158/0008-5472.CAN-04-1677, 15735046
    • Shiau CW, Yang CC, Kulp SK, Chen KF, Chen CS, Huang JW, Chen CS. Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma. Cancer Res 2005, 65(4):1561-1569. 10.1158/0008-5472.CAN-04-1677, 15735046.
    • (2005) Cancer Res , vol.65 , Issue.4 , pp. 1561-1569
    • Shiau, C.W.1    Yang, C.C.2    Kulp, S.K.3    Chen, K.F.4    Chen, C.S.5    Huang, J.W.6    Chen, C.S.7
  • 55
    • 0032586875 scopus 로고    scopus 로고
    • Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells
    • 10.1016/S0014-5793(99)00871-6, 10428487
    • Takahashi N, Okumura T, Motomura W, Fujimoto Y, Kawabata I, Kohgo Y. Activation of PPARgamma inhibits cell growth and induces apoptosis in human gastric cancer cells. FEBS Lett 1999, 455(1-2):135-139. 10.1016/S0014-5793(99)00871-6, 10428487.
    • (1999) FEBS Lett , vol.455 , Issue.1-2 , pp. 135-139
    • Takahashi, N.1    Okumura, T.2    Motomura, W.3    Fujimoto, Y.4    Kawabata, I.5    Kohgo, Y.6
  • 56
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • 10.1073/pnas.95.15.8806, 21158, 9671760
    • Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, Shintaku P, Said JW, Heber D, Koeffler HP. Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA 1998, 95(15):8806-8811. 10.1073/pnas.95.15.8806, 21158, 9671760.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.15 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 57
    • 0035019640 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells
    • 10.1210/jc.86.5.2170, 11344222
    • Ohta K, Endo T, Haraguchi K, Hershman JM, Onaya T. Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells. J Clin Endocrinol Metab 2001, 86(5):2170-2177. 10.1210/jc.86.5.2170, 11344222.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.5 , pp. 2170-2177
    • Ohta, K.1    Endo, T.2    Haraguchi, K.3    Hershman, J.M.4    Onaya, T.5
  • 58
    • 0038312167 scopus 로고    scopus 로고
    • HTERT mRNA expression correlates with telomerase activity in human breast cancer
    • 10.1053/ejso.2002.1374, 12711283
    • Kirkpatrick KL, Clark G, Ghilchick M, Newbold RF, Mokbel K. hTERT mRNA expression correlates with telomerase activity in human breast cancer. Eur J Surg Oncol 2003, 29(4):321-326. 10.1053/ejso.2002.1374, 12711283.
    • (2003) Eur J Surg Oncol , vol.29 , Issue.4 , pp. 321-326
    • Kirkpatrick, K.L.1    Clark, G.2    Ghilchick, M.3    Newbold, R.F.4    Mokbel, K.5


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