Design, synthesis and 3-d characterization of 1-benzenesulfonyl-1,2,3,4-tetrahydroquinolines as lead scaffold for antiparasitic drug

Letters in Drug Design and Discovery

Volumn 7, Issue 6, 2010, Pages 461-470

  Pagliero, R J ^a   Pierini, A B ^a   Brun, R ^b   Mazzieri, M R ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Antiparasitic; Benzenesulfonyl; Stereoelectronic properties; Tetrahydroquinolines

Indexed keywords

1 (3 NITRO BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 ACETAMIDE BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 AMINE BENZENOSULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 BROMO BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 CHLORO BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 FLUORO BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 METHOXY BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 METHYL BENZENESULFONYL)1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 NITRO BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1 (BENZENESULFONYL) 1,2,3,4 TETRAHYDROQUINOLINE; 1,2,3,4 TETRAHYDROQUINOLINE DERIVATIVE; ANTIPARASITIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SYNTHESIS; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RAT; TRYPANOSOMA CRUZI;

EID: 77954756739     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018010791306614     Document Type: Article

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