Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 142-150

  Pagliero, Romina J ^a   Lusvarghi, Sabrina ^a   Pierini, Adriana B ^a   Brun, Reto ^b   Mazzieri, María R ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Antiparasitic; Benzenesulfonyl; Stereoelectronic properties; Tetrahydroquinolines

Indexed keywords

1 (3 NITRO BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 ACETAMIDE BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 AMINO BENZENOSULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 BROMO BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 CHLORO BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 FLUORO BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 METHOXY BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 (4 METHYL BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLONE; 1 (4 NITRO BENZENESULFONYL) 2 METHYL 1,2,3,4-TETRAHYDROQUINOLINE; 1 (BENZENESULFONYL) 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 1 BENZENESULFONYL 2 METHYL 1,2,3,4 TETRAHYDROQUINOLINE DERIVATIVE; ANTIPROTOZOAL AGENT; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONFORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HYDROGEN BOND; MOLECULAR MODEL; NONHUMAN; PLASMODIUM FALCIPARUM; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION; TRYPANOZOMA CRUZI; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; HUMANS; LEISHMANIA DONOVANI; MODELS, MOLECULAR; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PROTOZOAN INFECTIONS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA; TRYPANOSOMA CRUZI;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 72049115481     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.010     Document Type: Article

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