Assessment of the intrinsic and stability properties of the freeze-dried and formulated extract of Hibiscus sabdariffa Linn. (Malvaceae)

African Journal of Pharmacy and Pharmacology

Volumn 4, Issue 6, 2010, Pages 304-313

  Builders, Philip F ^a   Ezeobi, Chukwuemeka R ^a   Tarfa, Florence D ^a   Builders, Modupe I ^b  

^a NATIONAL INSTITUTE FOR PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (Nigeria)

^b UNIVERSITY OF JOS   (Nigeria)

Author keywords

Formulation properties; Hibiscus sabdariffa; Physicochemical properties; Stability properties

Indexed keywords

BALSAM; FLAVONOID; GLYCOSIDE; HIBISCUS SABDARIFFA EXTRACT; MONOSACCHARIDE; PHENOL DERIVATIVE; STEROL;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; FREEZE DRYING; INFRARED SPECTROSCOPY; MOISTURE; PH; PHOTODEGRADATION; PHYSICAL CHEMISTRY; PHYTOCHEMISTRY;

EID: 77954675864     PISSN: None     EISSN: 19960816     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Ali BH, Al Wabe N, Blunden G (2005). Phytochemical, pharmacological and toxicological aspects of Habiscus sabdariffa L.: A review. Phytother. Res., 19(15): 369-375.
2. Aliyu L (2000). Roselle (Hibiscus sabdariffa L.). J. Applied Agric. Technol., 6: 16-20.
3. Andriambeloson E (1998). Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. J. Nutr., 128(12): 2324-2333.
4. Attoe EL, Von EJH (2006). Photochemial degradation of betanine and selected anthocyanins. J. Food Sci., 46 (6): 1934-1937.
5. Babalola SO, Babalola AO, Aworh OC (2000). Copositional attributes of the calyces of roselle (Hibiscus sabdariffa. L). J. Food Technol. Afr., 6: 133-134.
6. Bell L, Labuza TP (2000). Moisture sorption: practical aspects of isotherm measurement and use, 2nd ed. St. Paul, MN: American Association of Cereal Chemists.
7. Beristain C, Perez-Alonso IC, Lobato-Calleros C, Rodriguez-Huezo ME, Vernon-Carter EJ (2006). Thermodynamic analysis of the sorption isotherms of pure and blended carbohydrate polymers. J. Food Eng., 77: 753-760.
8. British P (2004). London: Stationery office.
9. Builders PF, Kunle OO, Adikwu MU (2008). Preparation and characterization of mucinated agarose: A mucin-agarose physical crosslink. Int. J. Pharm., 356: 174-180.
10. Callahan JC, Cleary GW, Elefant M, Kaplan G, Kensler T, Nash RA (1982). Equilibrium moisture content of pharmaceutical excipients. Drug Dev. Ind. Pharm., 8: 355-369.
11. Chifundera K, Balagizi K, Kizungu B (1994). Les empoisonnements et leurs antidotes en me ́ decine traditionnelle au Bushi, Zaire. Fitoterapia, 65: 307-313.
12. Elliot WE (1992). Inhibition of glutathione reductase by flavonoids. A structure-activity study. Biochem Pharmacol., 44(8): 1603-1608.
13. Fasoyiro SB, Ashaye OA, Adeola A, Samuel FO (2005). Chemical and storability of fruit-flavoured (Hibiscus sabdariffa) Drinks. World J. Agric. Sci., 1(2): 165-168.
14. Hancock BC, Shamblin SL (1998) Water vapour sorption by pharmaceutical sugars. PSTT 8: 345-351.
15. Hong V, Wrostlad O (1990). Use of HPLC separation/photodiode array detection for characterisation of anthocyanin. J. Agric. Food chem, 38: 708-715.
16. Igarashi K, Kimura Y, Takenaka A (2000). Preventive effects of dietary cabbage acylated anthocyanins on paraquat-induced oxidative stress in rats. Biosci. Biotechnol. Biochem., 64(8): 1600- 1607.
17. Irani NG, Grotewold E (2006). Light-induced morphological alteration in anthocyanin-accumulating acuoles of maize cells; BMC Plant Biology http://www.biomedcentral.com/1471-2229/5/7.
18. Jack IR, Okorosaye-Orubite K (2008). Phytochemical analysis and antimicrobial activity of the extract of leaves of fleabane (Conyza sumatrensis). J. Appl. Sci. Environ., 12(4): 63-65.
19. Kanner J, Lapidot T (2001). The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plant-derived antioxidants. Free Radic. Biol. Med., 31: 1388-1395.
20. Kontny MJ, Zografi G (1995). Sorption of water by solids. In Physical characterization of pharmaceutical solids. Brittain HG (ed.), Marcel Dekker Inc., New York, pp 387-418.
21. Krishnaiah D, Devi T, Bono A, Sarbatly R (2009). Studies on phytochemical constituents of six Malaysian medicinal plants. J. Med. Plts. Res., 3(2): 067-072.
22. Laleh GH, Frydoonfar H, Heidary R, Jameei R, Zare S (2006). The Effect of light, temperature, pH and species on stability of anthocyanin pigments in Four Berberis Species. Pakt. J. Nutr., 5(1): 90-92.
23. Leung AY (1980). Encyclopedia of common natural ingredients used in food, drugs, and cosmetics. Wiley and Sons New York.
24. Lin YC, Chen X (2005). Moisture sorption-desorption-resorption characteristics and its effect on the mechanical behaviour of the epoxy system. Polymer, 46: 11994-12003.
25. López-Serrano M, Ros BA (1999). Purification and characterization of a basic peroxidase isoenzyme from strawberries. Food Chem., 55(2): 133-137.
26. Lotito SB, Frei B (2006). Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon. Free Radic. Biol. Med., 41(12): 1727-46.
27. Niloufer GI, Frantisek P, Antje F, Yuhua L, Lucille P, Kenneth F, Erich G (2007). A trafficking pathway for anthocyanins overlaps with the endoplasmic reticulum-to-vacuole protein-sorting route in arabidopsis and contributes to the formation of vacuolar inclusions. Plant Physiol., 145: 1323-1335.
28. Olaniyi AA (2000). Principles of drug quality assurance and pharmaceutical analysis. Musoro Publishers, Ibadan. pp. 336-340.
29. Oyelade OJ, Tunde-Akintunde TY, Igbeka JC (2008). Predictive equilibrium moisture content equations for yam (Dioscorea rotundata, Poir) flour and hysteresis phenomena under practical storage conditions J. Food Eng., 87(2): 229-235.
30. Parkouda C, Diawara 1B, Ouoba ILI (2008). Technology and physico- chemical characteristics of Bikalga, alkaline fermented seeds of Hibiscus sabdariffa. Afri. J. Biotech., 7(7): 916-922.
31. Qi Y, Chin K, Malekian LF, Berhame M, Gager J (2005). Biological characteristics, nutritional and medicinal value of Roselle Hibiscus sabdariffa. Circular- Urban Forestry Natural Res. Environ., 604: 1-2.
32. Roos Y (1995). Phase transitions in foods, Academic Press, San Diego, USA. pp. 650-780.
33. Rouquerol F, Rouquerol J, Sing K (1999). In: Adsorption by powders and porous solids, Academic Press, London, Great Britain, pp. 212-320.
34. Sherman CP (1997). Infrared Spectroscopy In: Settle AF, Handbook of Instrumental Techniques for Analytical Chemistry. Prentice Hall; Har/Cdr edition Chapter 15.
35. Sing KSW, Everett DH, Haul RAW, Moscou L, Pierotti RA, Rouquerol J, Siemieniewska T (1985). Reporting physisorption data for gas/solid systems with special reference to the determination of surface area and porosity (recommendations). Pure Appl. Chem., 57: 603-619.
36. Sofowora A (1993). Medicinal plants and traditional medicines in Africa. Chichester John Wiley and Sons New York. pp. 97-145.
37. Swaminathan V, Kildsig DO (2001). An Examination of the moisture sorption characteristics of commercial magnesium stearate. AAPS Pharm. Sci. Tech., 2(4): article 28. www.aapspharmscitech.org. Accessed 12/8/2009.
38. Takeoka GR, Dao LT, Full GH, Wong RY, Harden LA, Edwards RH, Berrious JJ (1997).Characterization of black bean (Phaseolus vulgaris L) anthocyanin. J. Agric. Food Chem., 45: 3395-3400.
39. Trease GE, Evans WC (1978). Pharmacology 11th Ed. Bailliere Tindall Ltd, London. pp. 60-75.
40. Van CL, Amidon GL, Zografi G (1983). Moisture sorption kinetics for water-soluble substances I: Theoretical considerations of heat transport control. J. Pharm. Sci., 72: 1381-1388.
41. Wang W, Xu S (2007). Degradation kinetics of anthocyanins in blackberry juice and concentrate. J. Food Eng., 82(3): 271-275.
42. Wang SY, Jiao H (2000). Scavenging capacity of berry crops on superoxide radicals, hydrogen peroxide, hydroxyl radicals, and singlet oxygen. J. Agric. Food Chem., 48(11): 5677-5684.
43. Wiki D (2010). e.n. wikipedia.org/wiki/Malvaceae. Accessed 20/01/2010
44. Wong P, Salmah YHM, Cheman YB (2002). Physico-chemical characteristics of roselle (Hibiscus sabdariffa l.). Nutr. Food Sci., 32: 68-73.