Oxidative stress and inflammatory parameters after an ironman race

Clinical Journal of Sport Medicine

Volumn 20, Issue 4, 2010, Pages 306-311

  Pinho, Ricardo A ^a   Silva, Luciano A ^a   Pinho, Cleber A ^a   Scheffer, Débora L ^a   Souza, Cláudio T ^a   Benetti, Magnus ^b   Carvalho, Tales ^b   Dal Pizzol, Felipe ^a  

^a UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^b SANTA CATARINA STATE UNIVERSITY   (Brazil)

Author keywords

free radical; inflammation; Ironman; oxidative stress; triathletes

Indexed keywords

BIOLOGICAL MARKER; CATALASE; CYTOKINE; FREE RADICAL; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ATHLETE; BLOOD SAMPLING; CLINICAL ARTICLE; COMPETITION; CYCLING; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ENZYME ASSAY; ERYTHROCYTE; HUMAN; HUMIDITY; INFLAMMATION; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RUNNING; SERUM; SPORT; SWIMMING; TRIATHLON;

ADULT; BIOLOGICAL MARKERS; CATALASE; CYTOKINES; HUMANS; LIPID PEROXIDATION; LIPID PEROXIDES; MALE; OXIDATIVE STRESS; PHYSICAL ENDURANCE; PHYSICAL EXERTION; PROTEIN CARBONYLATION; SPORTS; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 77954617083     PISSN: 1050642X     EISSN: None     Source Type: Journal    
DOI: 10.1097/JSM.0b013e3181e413df     Document Type: Article

References (45)

1. Smith LL, Anwar A, Fragen M, et al. Cytokines and cell adhesion molecules associated with high-intensity eccentric exercise. Eur J Appl Physiol. 2000;82:61-67.
2. Hew-Butler T, Collins M, Bosch A, et al. Maintenance of plasma volume and serum sodium concentration despite body weight loss in Ironman triathletes. Clin J Sport Med. 2007;17:116-122.
3. Suzuki K, Peake J, Nosaka K, et al. Changes in markers of muscle damage, inflammation and HSP70 after an Ironman Triathlon race. Eur J Appl Physiol. 2006;98:525-534.
4. Knez WL, Jenkins DG, Coombes JS. Oxidative stress in half and full Ironman triathletes. Med Sci Sports Exerc. 2007;39:283-288.
5. Pinho RA, Andrades ME, Oliveira MR, et al. Imbalance in SOD/CAT activities in rat skeletal muscles submitted to treadmill training exercise. Cell Biol Int. 2006;30:848-853.
6. Carmeli E, Laviam G, Reznick AZ. The role of antioxidant nutrition in exercise and aging. In: Radák Z, ed. Free Radicals in Exercise and Aging. Champaign, IL: Human Kinetics, 2000:73-115.
7. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 4th ed. New York, NY: Clarendon Press; 2007.
8. Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol. 2005;98:1154-1162.
9. König D, Berg A. Exercise and oxidative stress: is there a need for additional antioxidants. Österreichisches J Für Sportmedizin. 2002;3: 6-15.
10. Meydani SN, Meydani M, Blumberg JB, et al. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA. 1997;277:1380-1386.
11. Avery NG, Kaiser JL, Sharman ML, et al. Effects of vitamin E supplementation on recovery from repeated bouts of resistance exercise. J Strength Cond Res. 2003;17:801-809.
12. Knez WL, Coombes JS, Jenkins DG. Ultra-endurance exercise and oxidative damage: implications for cardiovascular health. Sports Med. 2006;6:429-441.
13. Radak Z, Apor P, Pucsok J, et al. Marathon running alters the DNA base excision repair in human skeletal muscle. Life Sci. 2003;72:1627-1633.
14. Child RB, Wilkinson DM, Fallowfield JL, et al. Elevated serum antioxidant capacity and plasma malondialdehyde concentration in response to a simulated half-marathon run. Med Sci Sports Exerc. 1998;30:1603-1607.
15. Mastaloudis A, Leonard S, Traber M. Oxidative stress in athletes during extreme endurance exercise. Free Radic Biol Med. 2001;31: 911-922.
16. Radak Z, Pucsuk J, Boros S, et al. Changes in urine 8-hydroxydeox- yguanosine levels of super-marathon runners during a four-day race period. Life Sci. 2000;66:1763-1767.
17. McAnulty SR, McAnulty LS, Nieman DC, et al. Effect of alpha-tocopherol supplementation on plasma homocysteine and oxidative stress in highly trained athletes before and after exhaustive exercise. J Nutr Biochem. 2005;16:530-537.
18. Nieman DC. Special feature for the Olympics: effects of exercise on the immune system: exercise effects on systemic immunity. Immunol Cell Biol. 2000;78:496-501.
19. Cannon SC, Blumberg JB. Acute phase immune responses in exercise. In: Sen CK, Packer L, Hänninen O, eds. Handbook of Oxidants and Antioxidants in Exercise. Amsterdam, the Netherlands: Elsevier; 2000: 177-194.
20. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 1990;186:421-431.
21. 2+ in the presence of xylenol orange. Comparison with the TBA assay and an iodometric method. Lipids. 1991;26:853-856.
22. Levine RL, Garland D, Oliver CN, et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 1990;186: 464-478.
23. Bannister JV, Calabrese L. Assays for SOD. Methods Biochem Analyt. 1987;32:279-812.
24. Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121-126.
25. Lowry OH, Rosebough NG, Farr AL, et al. Protein measurement with the folin phenol reagent. J Biol Chem. 1951;193:265-275.
26. Neubauer O, Konig D, Kern N, et al. No indications of persistent oxidative stress in response to an Ironman Triathlon. Med Sci Sports Exerc. 2008; 40:2119-2128.
27. McBride JM, Kraemer WJ, Triplett-McBride T, et al. Effect of resistance exercise on free radical production. Med Sci Sports Exerc. 1998;30:67-72.
28. Goldfarb AH, Bloomer RJ, Mckenzie MJ. Combined antioxidant treatment effects on blood oxidative stress after eccentric exercise. Med Sci Sports Exerc. 2005;37:234-239.
29. Calabrese V, Scapagnini G, Colombrita C, et al. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach. Amino Acids. 2003;25:437-444.
30. McArdle A, Pattwell D, Vasilak A, et al. Contractile activity-induced oxidative stress: cellular origin and adaptive responses. Am J Physiol Cell Physiol. 2001;280:621-627.
31. Szweda PA, Friguet B, Szweda LI. Proteolysis, free radicals, and aging. Free Radic Biol Med. 2002;33:29-36
32. Liu ML, Bergholm R, Makimattila S, et al. A marathon run increases the susceptibility of LDL to oxidation in vitro and modifies plasma antioxidants. Am J Physiol. 1999;276:1083-1091.
33. Selamoglu S, Turgay F, Kayatekin BM, et al. Aerobic and anaerobic training effects on the antioxidant enzymes in the blood. Acta Physiol Hung. 2000;87:267-273.
34. Finaud J, Lac G, Filaire E. Oxidative stress relationship with exercise and training. Sports Med. 2006;36:327-358.
35. Fisher-Wellman K, Bloomer R. Acute exercise and oxidative stress: a 30 year history. Dynamic Med. 2009;8:1-25.
36. Margaritis I, Tessier F, Richard MJ, et al. No evidence of oxidative stress after a triathlon race in highly trained competitors. Int J Sports Med. 1997; 18:186-190.
37. Pedersen BK, Steensberg A, Fischer C, et al. The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? Proc Nutr Soc. 2004; 63:263-267.
38. Ostrowski K, Rohde T, Asp S, et al. Pro-and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol. 1999;515:287-291.
39. Suzuki K, Nakaji S, Yamada M, et al. Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc Immunol Rev. 2002;8:6-48.
40. Pedersen BK, Steensberg A, Schjerling P. Muscle-derived interleukin-6: possible biological effects. J Physiol. 2001;536:329-337.
41. Steensberg A, Dalsgaard MK, Secher NH, et al. Cerebrospinal fluid IL-6, HSP72, and TNF-alpha in exercising humans. Brain Behav Immun. 2006; 20:585-589.
42. Pedersen BK, Steensberg A, Fischer C, et al. Searching for the exercise factor: is IL-6 a candidate? J Muscle Res Cell Motil. 2003;24:113-119.
43. Suzuki K, Nakaji S, Yamada M, et al. Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc Immunol Rev. 2002;8:6-48.
44. Neubauer O, Konig D,Wagner K-H. Recovery after an Ironman Triathlon: sustained inflammatory responses and muscular stress. Eur J Appl Physiol. 2008;104:417-426.
45. Lancaster GI. Exercise and cytokines. In: Neil C, Gleeson M, MacLaren D, eds. Immune Function in Sport and Exercise. New York, NY: Elsevier; 2006:205-220.