Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: Its inhibition by quercetin

Apoptosis

Volumn 15, Issue 7, 2010, Pages 850-863

  Sun, Zhi Jun ^a   Chen, Gang ^a   Hu, Xiang ^a   Zhang, Wei ^a   Liu, Yang ^a   Zhu, Ling Xin ^a   Zhou, Qian ^a   Zhao, Yi Fang ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Adenoid cystic carcinoma; Akt; Apoptosis; NF B; Quercetin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; QUERCETIN; ANTINEOPLASTIC AGENT; CASPASE; I KAPPA B KINASE;

ADENOID CYSTIC CARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL NUCLEUS; CELL VIABILITY; CLUSTER ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; METASTASIS; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR XENOGRAFT; UBIQUITINATION; ANIMAL; DRUG ANTAGONISM; DRUG SCREENING; ENZYMOLOGY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; NUDE MOUSE; PATHOLOGY; SALIVARY GLAND TUMOR; TUMOR CELL LINE;

MUS MUSCULUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, ADENOID CYSTIC; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MITOCHONDRIA; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; QUERCETIN; SALIVARY GLAND NEOPLASMS; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77954604880     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0497-5     Document Type: Article

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