Proteomic analyses of caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates a shared detoxification system in longevity assurance

Journal of Proteome Research

Volumn 9, Issue 6, 2010, Pages 2871-2881

  Jones, Laura M ^a   Staffa, Katharina ^a   Perally, Samïrah ^a   LaCourse, E James ^b   Brophy, Peter M ^a   Hamilton, Jo V ^a  

^a ABERYSTWYTH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

2 de; C. elegans; daf 2; dauer; glutathione peroxidise; glutathione transferase; GST 1; heat shock protein; HSP 12.6; IIS; Insulin igf 1 signaling; LBP 6; lipid binding protein; longevity; proteomics; ribosomal protein; RNAI; RPS 12; SOD 1; superoxide dismutase

Indexed keywords

ALDEHYDE; ALPHA CRYSTALLIN; ANTIOXIDANT; DAF 2 MUTANT PROTEIN; FATTY ACID; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN; LIPID BINDING PROTEIN; MUTANT PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

AGING; ARTICLE; BIOSYNTHESIS; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DETOXIFICATION; ENERGY CONSUMPTION; LARVA; LIPID PEROXIDATION; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN TARGETING; PROTEOMICS; RNA INTERFERENCE; SURVIVAL; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYTOSOL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLUTATHIONE S-TRANSFERASE PI; INHIBITORY CONCENTRATION 50; LARVA; LONGEVITY; METABOLIC DETOXICATION, DRUG; METABOLIC NETWORKS AND PATHWAYS; MUTATION; RECEPTOR, INSULIN; RNA INTERFERENCE;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MUS MUSCULUS;

EID: 77954569980     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr9009639     Document Type: Article

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