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Volumn 21, Issue 7, 2010, Pages 2027-2034

Novel mucoadhesive system based on sulfhydryl-acrylate interactions

Author keywords

[No Author keywords available]

Indexed keywords

END GROUPS; HYDROPHILIC DRUGS; IN-SITU; MACROMERS; MATRIX; MUCOADHESION; MUCOADHESIVE POLYMERS; NMR STUDIES; PROOF OF CONCEPT; RHEOLOGY MEASUREMENT; SULFHYDRYL; SUSTAINED RELEASE; SYSTEM-BASED; TENSILE MEASUREMENTS; VINYL PROTONS; VISCOSITY INCREASE;

EID: 77954536390     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-010-4069-6     Document Type: Article
Times cited : (46)

References (43)
  • 1
    • 0001015279 scopus 로고    scopus 로고
    • Mucoadhesive polymers
    • S. Dumitriu Dumitriu Ss (eds). Marcel Dekker, Inc New York
    • Bernkop-Schnurch A. Mucoadhesive polymers. In: Dumitriu S, Ss Dumitriu, editors. Polymer biomaterial. New York: Marcel Dekker, Inc; 2002. p. 147-65.
    • (2002) Polymer Biomaterial , pp. 147-165
    • Bernkop-Schnurch, A.1
  • 2
    • 0033813758 scopus 로고    scopus 로고
    • Bioadhesive-based dosage forms: The next generation
    • 10.1002/1520-6017(200007)89:7<850::AID-JPS2>3.0.CO;2-G 1:CAS:528:DC%2BD3cXlt1ahtbk%3D 10861586
    • JW Lee JH Park JR Robinson 2000 Bioadhesive-based dosage forms: the next generation J Pharm Sci 89 850 866 10.1002/1520-6017(200007)89:7<850::AID- JPS2>3.0.CO;2-G 1:CAS:528:DC%2BD3cXlt1ahtbk%3D 10861586
    • (2000) J Pharm Sci , vol.89 , pp. 850-866
    • Lee, J.W.1    Park, J.H.2    Robinson, J.R.3
  • 3
    • 0026571343 scopus 로고
    • Mucin-type glycoproteins
    • 10.3109/10409239209082559 1:CAS:528:DyaK38XltlOrtQ%3D%3D 1727693
    • GJ Strous J Dekker 1992 Mucin-type glycoproteins Crit Rev Biochem Mol Biol 27 57 92 10.3109/10409239209082559 1:CAS:528:DyaK38XltlOrtQ%3D%3D 1727693
    • (1992) Crit Rev Biochem Mol Biol , vol.27 , pp. 57-92
    • Strous, G.J.1    Dekker, J.2
  • 4
    • 0033527547 scopus 로고    scopus 로고
    • The structure and assembly of secreted mucins
    • DOI 10.1074/jbc.274.45.31751
    • J Perez-Vilar RL Hill 1999 The structure and assembly of secreted mucins J Biol Chem 274 31751 31754 10.1074/jbc.274.45.31751 1:CAS:528: DyaK1MXnt12jsrg%3D 10542193 (Pubitemid 29522897)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.45 , pp. 31751-31754
    • Ferez-Vilar, J.1    Hill, R.L.2
  • 5
    • 0036495626 scopus 로고    scopus 로고
    • The MUC family: An obituary
    • DOI 10.1016/S0968-0004(01)02052-7, PII S0968000401020527
    • J Dekker JWA Rossen HA Buller AWC Einerhand 2002 The MUC family: an obituary Trends Biochem Sci 27 126 131 10.1016/S0968-0004(01)02052-7 1:CAS:528:DC%2BD38XhvVWhtb0%3D 11893509 (Pubitemid 34219322)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.3 , pp. 126-131
    • Dekker, J.1    Rossen, J.W.A.2    Buller, H.A.3    Einerhand, A.W.C.4
  • 6
    • 0347985635 scopus 로고    scopus 로고
    • Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: Synthesis and in vitro evaluation
    • DOI 10.1016/S0939-6411(03)00157-7
    • M Roldo M Hornof P Caliceti A Bernkop-Schnurch 2004 Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: synthesis and in vitro evaluation Eur J Pharm Biopharm 57 115 121 10.1016/S0939-6411(03) 00157-7 1:CAS:528:DC%2BD2cXjsFakug%3D%3D 14729087 (Pubitemid 38058810)
    • (2004) European Journal of Pharmaceutics and Biopharmaceutics , vol.57 , Issue.1 , pp. 115-121
    • Roldo, M.1    Hornof, M.2    Caliceti, P.3    Bernkop-Schnurch, A.4
  • 7
    • 0042140521 scopus 로고    scopus 로고
    • Thiolated polymers: Evidence for the formation of disulphide bonds with mucus glycoproteins
    • DOI 10.1016/S0939-6411(03)00061-4
    • VM Leitner GF Walker A Bernkop-Schnurch 2003 Thiolated polymers: evidence for the formation of disulfide bonds with mucus glycoproteins Eur J Pharm Biopharm 56 207 214 10.1016/S0939-6411(03)00061-4 1:CAS:528:DC%2BD3sXmvFSjtrw%3D 12957634 (Pubitemid 37072104)
    • (2003) European Journal of Pharmaceutics and Biopharmaceutics , vol.56 , Issue.2 , pp. 207-214
    • Leitner, V.M.1    Walker, G.F.2    Bernkop-Schnurch, A.3
  • 8
    • 26644452975 scopus 로고    scopus 로고
    • Thiomers: A new generation of mucoadhesive polymers
    • DOI 10.1016/j.addr.2005.07.002, PII S0169409X05001407, Mucoadhesive Polymers: Strategies, Achievements and Future Challenges
    • A Bernkop-Schnuerch 2005 Thiomers: a new generation of mucoadhesive polymers Adv Drug Deliv Rev 57 1569 1582 10.1016/j.addr.2005.07.002 1:CAS:528:DC%2BD2MXhtFSis7fJ (Pubitemid 41443470)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.11 , pp. 1569-1582
    • Bernkop-Schnurch, A.1
  • 9
    • 0034925740 scopus 로고    scopus 로고
    • Thiolated polymers - thiomers: Development and in vitro evaluation of chitosan-thioglycolic acid conjugates
    • DOI 10.1016/S0142-9612(00)00421-X, PII S014296120000421X
    • CE Kast A Bernkop-Schnurch 2001 Thiolated polymers-thiomers: development and in vitro evaluation of chitosan-thioglycolic acid conjugates Biomaterials 22 2345 2352 10.1016/S0142-9612(00)00421-X 1:CAS:528:DC%2BD3MXlt1Sitbg%3D 11511031 (Pubitemid 32666227)
    • (2001) Biomaterials , vol.22 , Issue.17 , pp. 2345-2352
    • Kast, C.E.1    Bernkop-Schnurch, A.2
  • 10
    • 0038460837 scopus 로고    scopus 로고
    • Thiolated polymers - Thiomers: Synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates
    • DOI 10.1016/S0378-5173(03)00271-0
    • A Bernkop-Schnurch M Hornof T Zoidl 2003 Thiolated polymers-thiomers: synthesis and in vitro evaluation of chitosan-2-iminothiolane conjugates Int J Pharm 260 229 237 10.1016/S0378-5173(03)00271-0 1:CAS:528:DC%2BD3sXkvFektL4%3D 12842342 (Pubitemid 36773920)
    • (2003) International Journal of Pharmaceutics , vol.260 , Issue.2 , pp. 229-237
    • Bernkop-Schnurch, A.1    Hornof, M.2    Zoidl, T.3
  • 11
  • 12
    • 67349189475 scopus 로고    scopus 로고
    • Evaluating the mucoadhesive properties of drug delivery systems based on hydrated thiolated alginate
    • 10.1016/j.jconrel.2009.01.029 1:CAS:528:DC%2BD1MXlvFGjtLw%3D 19217920
    • M Davidovich-Pinhas O Harari H Bianco-Peled 2009 Evaluating the mucoadhesive properties of drug delivery systems based on hydrated thiolated alginate J Control Release 136 38 44 10.1016/j.jconrel.2009.01.029 1:CAS:528:DC%2BD1MXlvFGjtLw%3D 19217920
    • (2009) J Control Release , vol.136 , pp. 38-44
    • Davidovich-Pinhas, M.1    Harari, O.2    Bianco-Peled, H.3
  • 13
    • 0035210936 scopus 로고    scopus 로고
    • Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids
    • DOI 10.1021/bc015519e
    • MP Lutolf N Tirelli S Cerritelli L Colussi JA Hubbell 2001 Systematic modulation of michael-type reactivity of thiols through the use of charged amino acids Bioconjug Chem 12 1051 1056 10.1021/bc015519e 1:CAS:528: DC%2BD3MXmvFSgtr0%3D 11716699 (Pubitemid 33136878)
    • (2001) Bioconjugate Chemistry , vol.12 , Issue.6 , pp. 1051-1056
    • Lutolf, M.P.1    Tirelli, N.2    Cerritelli, S.3    Cavalli, L.4    Hubbell, J.A.5
  • 14
    • 0038516829 scopus 로고    scopus 로고
    • Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition
    • DOI 10.1021/bm025744e
    • MP Lutolf JA Hubbell 2003 Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition Biomacromolecules 4 713 722 10.1021/bm025744e 1:CAS:528: DC%2BD3sXhsVaqurw%3D 12741789 (Pubitemid 36701243)
    • (2003) Biomacromolecules , vol.4 , Issue.3 , pp. 713-722
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 15
    • 33846447043 scopus 로고    scopus 로고
    • Michael-type addition reactions for the in situ formation of poly(vinyl alcohol)-based hydrogels
    • DOI 10.1021/bm0607269
    • M Tortora F Cavalieri E Chiessi G Paradossi 2007 Michael-type addition reactions for the in situ formation of poly(vinyl alcohol)-based hydrogels Biomacromolecules 8 209 214 10.1021/bm0607269 1:CAS:528:DC%2BD28Xht1yiur3M 17206809 (Pubitemid 46140494)
    • (2007) Biomacromolecules , vol.8 , Issue.1 , pp. 209-214
    • Tortora, M.1    Cavalieri, F.2    Chiessi, E.3    Paradossi, G.4
  • 16
    • 13944255099 scopus 로고    scopus 로고
    • Degradable thiol-acrylate photopolymers: Polymerization and degradation behavior of an in situ forming biomaterial
    • DOI 10.1016/j.biomaterials.2004.11.046, PII S0142961204010506
    • AE Rydholm CN Bowman KS Anseth 2005 Degradable thiol-acrylate photopolymers: polymerization and degradation behavior of an in situ forming biomaterial Biomaterials 26 4495 4506 10.1016/j.biomaterials.2004.11.046 1:CAS:528:DC%2BD2MXhs1GgtLw%3D 15722118 (Pubitemid 40269265)
    • (2005) Biomaterials , vol.26 , Issue.22 , pp. 4495-4506
    • Rydholm, A.E.1    Bowman, C.N.2    Anseth, K.S.3
  • 17
    • 33645825387 scopus 로고    scopus 로고
    • Viscoelastic behavior of environmentally sensitive biomimetic polymer matrices
    • 10.1021/ma0524528 1:CAS:528:DC%2BD28Xhs1Gqtr4%3D 2006MaMol.39.2268S
    • BL Seal A Panitch 2006 Viscoelastic behavior of environmentally sensitive biomimetic polymer matrices Macromolecules 39 2268 2274 10.1021/ma0524528 1:CAS:528:DC%2BD28Xhs1Gqtr4%3D 2006MaMol..39.2268S
    • (2006) Macromolecules , vol.39 , pp. 2268-2274
    • Seal, B.L.1    Panitch, A.2
  • 18
    • 10044290786 scopus 로고    scopus 로고
    • Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures
    • DOI 10.1016/j.biomaterials.2004.06.047, PII S014296120400609X
    • L Almany D Seliktar 2005 Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures Biomaterials 26 2467 2477 10.1016/j.biomaterials.2004.06.047 1:CAS:528:DC%2BD2cXhtVCiu7fK 15585249 (Pubitemid 39600699)
    • (2005) Biomaterials , vol.26 , Issue.15 , pp. 2467-2477
    • Almany, L.1    Seliktar, D.2
  • 19
    • 57049085726 scopus 로고    scopus 로고
    • Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
    • 10.1002/anie.200803526 1:CAS:528:DC%2BD1cXhsFamsr7F
    • Y-Y Wang SK Lai JS Suk A Race R Cone J Hanes 2008 Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier Angew Chem Int 47 9726 9729 10.1002/anie.200803526 1:CAS:528:DC%2BD1cXhsFamsr7F
    • (2008) Angew Chem Int , vol.47 , pp. 9726-9729
    • Wang, Y.-Y.1    Lai, S.K.2    Suk, J.S.3    Race, A.4    Cone, R.5    Hanes, J.6
  • 20
    • 0037022477 scopus 로고    scopus 로고
    • Direct measurement of interactions between tethered poly(ethylene glycol) chains and adsorbed mucin layers
    • DOI 10.1021/la011303p
    • NV Efremova Y Huang NA Peppas DE Leckband 2002 Direct measurement of interactions between tethered polyethylene glycol chains and adsorbed mucin layers Langmuir 18 836 845 10.1021/la011303p 1:CAS:528:DC%2BD38Xis1ykuw%3D%3D (Pubitemid 35384118)
    • (2002) Langmuir , vol.18 , Issue.3 , pp. 836-845
    • Efremova, N.V.1    Huang, Y.2    Peppas, N.A.3    Leckband, D.E.4
  • 21
    • 0034602106 scopus 로고    scopus 로고
    • Mucoadhesive drug carriers based on complexes of poly(acrylic acid) and PEGylated drugs having hydrolyzable PEG-anhydride-drug linkages
    • 10.1016/S0168-3659(00)00303-5 1:CAS:528:DC%2BD3cXovFSlsro%3D 11064131
    • BS Lele AS Hoffman 2000 Mucoadhesive drug carriers based on complexes of poly(acrylic acid) and PEGylated drugs having hydrolyzable PEG-anhydride-drug linkages J Control Release 69 237 248 10.1016/S0168-3659(00)00303-5 1:CAS:528:DC%2BD3cXovFSlsro%3D 11064131
    • (2000) J Control Release , vol.69 , pp. 237-248
    • Lele, B.S.1    Hoffman, A.S.2
  • 22
    • 0035858290 scopus 로고    scopus 로고
    • Surface modifications and molecular imprinting of polymers in medical and pharmaceutical applications
    • DOI 10.1016/S0168-3659(01)00259-0, PII S0168365901002590
    • P Bures Y Huang E Oral NA Peppas 2001 Surface modifications and molecular imprinting of polymers in medical and pharmaceutical applications J Control Release 72 25 33 10.1016/S0168-3659(01)00259-0 1:CAS:528:DC%2BD3MXktVGlu7c%3D 11389982 (Pubitemid 32522341)
    • (2001) Journal of Controlled Release , vol.72 , Issue.1-3 , pp. 25-33
    • Bures, P.1    Huang, Y.2    Oral, E.3    Peppas, N.A.4
  • 23
    • 23644437127 scopus 로고    scopus 로고
    • Bioadhesive properties of pegylated nanoparticles
    • DOI 10.1517/17425247.2.2.205
    • K Yoncheva S Gomez A Campanero Miguel C Gamazo M Irache Juan 2005 Bioadhesive properties of pegylated nanoparticles Expert Opin Drug Deliv 2 205 218 10.1517/17425247.2.2.205 1:CAS:528:DC%2BD2MXjsFansbY%3D 16296748 (Pubitemid 41130878)
    • (2005) Expert Opinion on Drug Delivery , vol.2 , Issue.2 , pp. 205-218
    • Yoncheva, K.1    Gomez, S.2    Campanero, M.A.3    Gamazo, C.4    Irache, J.M.5
  • 24
    • 0028837299 scopus 로고
    • Mucoadhesion of poly(2-hydroxyethyl methacrylate) is improved when linear poly(ethylene oxide) chains are added to the polymer network
    • 10.1016/0168-3659(94)00087-B 1:CAS:528:DyaK2MXjt1Srtb4%3D
    • AD Ascentiis JL deGrazia CN Bowman P Colombo NA Peppas 1995 Mucoadhesion of poly(2-hydroxyethyl methacrylate) is improved when linear poly(ethylene oxide) chains are added to the polymer network J Control Release 33 197 201 10.1016/0168-3659(94)00087-B 1:CAS:528:DyaK2MXjt1Srtb4%3D
    • (1995) J Control Release , vol.33 , pp. 197-201
    • Ascentiis, A.D.1    Degrazia, J.L.2    Bowman, C.N.3    Colombo, P.4    Peppas, N.A.5
  • 25
    • 0030898701 scopus 로고    scopus 로고
    • Enhanced hydrogel adhesion by polymer interdiffusion: Use of linear poly(ethylene glycol) as an adhesion promoter
    • 10.1163/156856297X00362 1:CAS:528:DyaK2sXjtl2qurs%3D 9151191
    • JJ Sahlin NA Peppas 1997 Enhanced hydrogel adhesion by polymer interdiffusion: use of linear poly(ethylene glycol) as an adhesion promoter J Biomater Sci Polym Ed 8 421 436 10.1163/156856297X00362 1:CAS:528: DyaK2sXjtl2qurs%3D 9151191
    • (1997) J Biomater Sci Polym Ed , vol.8 , pp. 421-436
    • Sahlin, J.J.1    Peppas, N.A.2
  • 26
    • 0034000923 scopus 로고    scopus 로고
    • Molecular aspects of muco- and bioadhesion: Tethered structures and site-specific surfaces
    • DOI 10.1016/S0168-3659(99)00233-3, PII S0168365999002333
    • Y Huang W Leobandung A Foss NA Peppas 2000 Molecular aspects of muco- and bioadhesion: tethered structures and site-specific surfaces J Control Release 65 63 71 10.1016/S0168-3659(99)00233-3 1:CAS:528:DC%2BD3cXhtl2qsrY%3D 10699271 (Pubitemid 30122916)
    • (2000) Journal of Controlled Release , vol.65 , Issue.1-2 , pp. 63-71
    • Huang, Y.1    Leobandung, W.2    Foss, A.3    Peppas, N.A.4
  • 27
    • 0001350902 scopus 로고
    • Gradient-tailored water suppression for proton-nitrogen-15 HSQC experiments optimized to retain full sensitivity
    • 10.1006/jmra.1993.1098 1:CAS:528:DyaK3sXktF2jtLs%3D
    • V Sklenar M Piotto R Leppik V Saudek 1993 Gradient-tailored water suppression for proton-nitrogen-15 HSQC experiments optimized to retain full sensitivity J Magn Reson Ser A 102 241 245 10.1006/jmra.1993.1098 1:CAS:528:DyaK3sXktF2jtLs%3D
    • (1993) J Magn Reson ser A , vol.102 , pp. 241-245
    • Sklenar, V.1    Piotto, M.2    Leppik, R.3    Saudek, V.4
  • 28
    • 0026951903 scopus 로고
    • Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
    • 10.1007/BF02192855 1:CAS:528:DyaK3sXitVyktrY%3D 1490109
    • M Piotto V Saudek V Sklenar 1992 Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions J Biomol NMR 2 661 665 10.1007/BF02192855 1:CAS:528:DyaK3sXitVyktrY%3D 1490109
    • (1992) J Biomol NMR , vol.2 , pp. 661-665
    • Piotto, M.1    Saudek, V.2    Sklenar, V.3
  • 29
    • 0032651157 scopus 로고    scopus 로고
    • Interactions between hydrophobically modified polyelectrolytes and mucin
    • 1:CAS:528:DyaK1MXlsFyqtbs%3D 1999nsi.book.B
    • LE Bromberg 1999 Interactions between hydrophobically modified polyelectrolytes and mucin Polym Prepr 40 616 617 1:CAS:528:DyaK1MXlsFyqtbs%3D 1999nsi..book.....B
    • (1999) Polym Prepr , vol.40 , pp. 616-617
    • Bromberg, L.E.1
  • 30
    • 0003898491 scopus 로고    scopus 로고
    • The royal society of chemistry Cambridge
    • Comyn J. Adhesion science. Cambridge: The royal society of chemistry; 1997.
    • (1997) Adhesion Science
    • Comyn, J.1
  • 31
    • 0002927440 scopus 로고
    • Theories and mechanisms of adhesion
    • A. Pizzi K.L. Mittal (eds). Marcel Dekker, Inc. New York
    • Schultz J, Nardin M. Theories and mechanisms of adhesion. In: Pizzi A, Mittal KL, editors. Handbook of adhesive technology. New York: Marcel Dekker, Inc.; 1994.
    • (1994) Handbook of Adhesive Technology
    • Schultz, J.1    Nardin, M.2
  • 33
    • 0035962381 scopus 로고    scopus 로고
    • Improvement in the mucoadhesive properties of alginate by the covalent attachment of cysteine
    • DOI 10.1016/S0168-3659(01)00227-9, PII S0168365901002279
    • A Bernkop-Schnurch CE Kast MF Richter 2001 Improvement in the mucoadhesive properties of alginate by the covalent attachment of cysteine J Control Release 71 277 285 10.1016/S0168-3659(01)00227-9 1:CAS:528: DC%2BD3MXitlOhsrk%3D 11295220 (Pubitemid 32276047)
    • (2001) Journal of Controlled Release , vol.71 , Issue.3 , pp. 277-285
    • Bernkop-Schnurch, A.1    Kast, C.E.2    Richter, M.F.3
  • 34
    • 76149139778 scopus 로고    scopus 로고
    • Mucoadhesion: A review of characterization techniques
    • 10.1517/17425240903473134 1:CAS:528:DC%2BC3cXht1Sms7s%3D 20095946
    • M Davidovich-Pinhas H Bianco-Peled 2010 Mucoadhesion: a review of characterization techniques Expert Opin Drug Deliv 7 259 271 10.1517/17425240903473134 1:CAS:528:DC%2BC3cXht1Sms7s%3D 20095946
    • (2010) Expert Opin Drug Deliv , vol.7 , pp. 259-271
    • Davidovich-Pinhas, M.1    Bianco-Peled, H.2
  • 37
    • 52949129126 scopus 로고    scopus 로고
    • Enhanced dissolution of ibuprofen using solid dispersion with polyethylene glycol 20,000
    • 10.1080/03639040701744095 1:CAS:528:DC%2BD1cXhtFKls7vK 18686087
    • M Newa KH Bhandari DX Lee JH Sung JA Kim BK Yoo JS Woo HG Choi CS Yong 2008 Enhanced dissolution of ibuprofen using solid dispersion with polyethylene glycol 20,000 Drug Dev Ind Pharm 34 1013 1021 10.1080/03639040701744095 1:CAS:528:DC%2BD1cXhtFKls7vK 18686087
    • (2008) Drug Dev Ind Pharm , vol.34 , pp. 1013-1021
    • Newa, M.1    Bhandari, K.H.2    Lee, D.X.3    Sung, J.H.4    Kim, J.A.5    Yoo, B.K.6    Woo, J.S.7    Choi, H.G.8    Yong, C.S.9
  • 38
    • 49549112726 scopus 로고    scopus 로고
    • Preparation and evaluation of fast dissolving ibuprofen-polyethylene glycol 6000 solid dispersions
    • 10.1080/10717540801952431 1:CAS:528:DC%2BD1cXptlSqtbo%3D 18686079
    • M Newa KH Bhandari J-A Kim B-K Yoo H-G Choi C-S Yong J-S Woo W-S Lyoo 2008 Preparation and evaluation of fast dissolving ibuprofen-polyethylene glycol 6000 solid dispersions Drug Deliv 15 355 364 10.1080/10717540801952431 1:CAS:528:DC%2BD1cXptlSqtbo%3D 18686079
    • (2008) Drug Deliv , vol.15 , pp. 355-364
    • Newa, M.1    Bhandari, K.H.2    Kim, J.-A.3    Yoo, B.-K.4    Choi, H.-G.5    Yong, C.-S.6    Woo, J.-S.7    Lyoo, W.-S.8
  • 41
    • 18544383452 scopus 로고    scopus 로고
    • High molecular weight poly(ethylene oxide)-based drug delivery systems. Part I: Hydrogels and hydrophilic matrix systems
    • S Dhawan M Varma VR Sinha 2005 High molecular weight poly(ethylene oxide)-based drug delivery systems. Part I: hydrogels and hydrophilic matrix systems Pharm Technol 29 72-74 76 80
    • (2005) Pharm Technol , vol.29 , Issue.7274 , pp. 76-80
    • Dhawan, S.1    Varma, M.2    Sinha, V.R.3
  • 42
    • 0023195932 scopus 로고
    • A simple equation for desciption of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
    • DOI 10.1016/0168-3659(87)90034-4
    • PL Ritger NA Peppas 1987 A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs J Control Release 5 23 36 10.1016/0168-3659(87)90034-4 1:CAS:528:DyaL2sXkvVeku7o%3D (Pubitemid 17106643)
    • (1987) Journal of Controlled Release , vol.5 , Issue.1 , pp. 23-36
    • Ritger, P.L.1    Peppas, N.A.2
  • 43
    • 0023196815 scopus 로고
    • A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
    • DOI 10.1016/0168-3659(87)90035-6
    • PL Ritger NA Peppas 1987 A simple equation for description of solute release II. Fickian and anomalous release from swellable devices J Control Release 5 37 42 10.1016/0168-3659(87)90035-6 1:CAS:528:DyaL2sXkvVeku7s%3D (Pubitemid 17106644)
    • (1987) Journal of Controlled Release , vol.5 , Issue.1 , pp. 37-42
    • Ritger, P.L.1    Peppas, N.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.