Adenosine receptor type 2a is differently modulated by nicotine in dorsal brainstem cells of Wistar Kyoto and spontaneously hypertensive rats

Journal of Neural Transmission

Volumn 117, Issue 7, 2010, Pages 799-807

  De Matsumoto, Joao Paulo Pontes ^a   De Ferrari, Merari Fatima Ramires ^a   Fior Chadi, Debora Rejane ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Adenosine A2a receptor; Hypertension; Medulla oblongata; Nicotine

Indexed keywords

ADENOSINE A2 RECEPTOR; MESSENGER RNA; NICOTINE; ADENOSINE A2A RECEPTOR; NICOTINIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN STEM; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; GENE EXPRESSION; MEDULLA OBLONGATA; NEUROMODULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; WISTAR KYOTO RAT; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; HYPERTENSION; METABOLISM; POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE; SPONTANEOUSLY HYPERTENSIVE RAT; TIME; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BRAIN STEM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION; MEDULLA OBLONGATA; NICOTINE; NICOTINIC AGONISTS; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, ADENOSINE A2A; RNA, MESSENGER; SPECIES SPECIFICITY; TIME FACTORS;

EID: 77954533373     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-010-0417-4     Document Type: Article

References (63)

1. Altman JA, Bayer AS (1995) Atlas of prenatal rat brain development. CRC Press, Boca Raton
2. RA Barraco MR El-Ridi E Ergene JW Phillis 1991 Adenosine receptor subtypes in the brainstem mediate distinct cardiovascular response patterns Brain Res Bull 26 59 84 10.1016/0361-9230(91)90192-M 1:CAS:528: DyaK3MXhslykt7c%3D 2015518
3. RA Barraco DS O'leary E Ergene TJ Scislo 1996 Activation of purinergic receptor subtypes in the nucleus tractus solitarius elicits specific regional vascular response patterns J Auton Nerv Syst 59 113 124 10.1016/0165-1838(96) 00014-8 1:CAS:528:DyaK28XkvFKmu7s%3D 8832517 (Pubitemid 26228170)
4. L Belardinelli JC Shryock S Snowdy Y Zhang A Monopoli G Lozza E Ongini RA Olsson DM Dennis 1998 The A2A adenosine receptor mediates coronary vasodilation J Pharmacol Exp Ther 284 1066 1073 1:CAS:528:DyaK1cXhs1ygs78%3D 9495868 (Pubitemid 28130836)
5. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D 942051
6. JJ Buccafusco X Yang 1993 Mechanism of the hypertensive response to central injection of nicotine in conscious rats Brain Res Bull 32 35 41 10.1016/0361-9230(93)90316-4 1:CAS:528:DyaK3sXlvFOlt7s%3D 8319101 (Pubitemid 23160578)
7. WA Carlezon RS Duman EJ Nestler 2005 The many faces of CREB Trends Neurosci 28 436 445 10.1016/j.tins.2005.06.005 1:CAS:528:DC%2BD2MXmsVOhtLk%3D 15982754 (Pubitemid 40982557)
8. DC Carrettiero DR Fior-Chadi 2004 Adenosine A1 receptor distribution in the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats J Neural Transm 111 465 473 10.1007/s00702-003-0104-9 1:CAS:528: DC%2BD2cXis1GgsLw%3D 15057516 (Pubitemid 38478914)
9. DC Carrettiero DR Fior-Chadi 2008 Age-dependent changes in adenosine A1 receptor distribution and density within the nucleus tractus solitarii of normotensive and hypertensive rats J Neural Transm 115 1109 1118 10.1007/s00702-008-0055-2 1:CAS:528:DC%2BD1cXht1ShurjI 18463780
10. M Castillo-Melendez E Krstew AJ Lawrence B Jarrott 1994 Presynaptic adenosine A2a receptors on soma and central terminals of rat vagal afferent neurons Brain Res 652 137 144 10.1016/0006-8993(94)90327-1 1:CAS:528: DyaK2cXltVSms7g%3D 7953710
11. JF Chen Z Huang J Ma J Zhu R Moratalla D Standaert MA Moskowitz JS Fink MA Schwarzschild 1999 A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice J Neurosci 19 9192 9200 1:CAS:528:DyaK1MXnslyisLc%3D 10531422
12. E Colombari MA Sato SL Cravo CT Bergamaschi RR Campos Jr OU Lopes 2001 Role of the medulla oblongata in hypertension Hypertension 38 549 554 1:CAS:528:DC%2BD3MXntFSrsb0%3D 11566929
13. RA Dampney 1994 Functional organization of central pathways regulating the cardiovascular system Physiol Rev 74 323 364 1:STN:280:DyaK2c3isV2ksA%3D%3D 8171117
14. JA Dani D Bertrand 2007 Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system Annu Rev Pharmacol Toxicol 47 699 729 10.1146/annurev.pharmtox.47.120505.105214 1:CAS:528: DC%2BD2sXit1alurk%3D 17009926
15. FN Dhar JM McIntosh HN Sapru 2000 Receptor subtypes mediating depressor responses to microinjections of nicotine into medial NTS of rats Am J Physiol Regul Integr Comp Physiol 279 132 140
16. RI Dmitrieva CA Hinojos ML Grove RJ Bell E Boerwinkle M Fornage PA Doris 2009 Genome-wide identification of allelic expression in hypertensive rats Circ Cardiovasc Genet 2 106 115 10.1161/CIRCGENETICS.108.809509 1:CAS:528: DC%2BD1MXmvVyhsLY%3D 20031574
17. AS Doggrell Brown 1998 Rat models of hypertension, cardiac hypertrophy and failure Cardiovasc Res 39 89 105 10.1016/S0008-6363(98)00076-5 1:CAS:528:DyaK1cXkvFOrur0%3D 9764192 (Pubitemid 28322382)
18. CP Fenster ML Beckman JC Parker EB Sheffield TL Whitworth MW Quick RA Lester 1999 Regulation of alpha4beta2 nicotinic receptor desensitization by calcium and protein kinase C Mol Pharmacol 55 432 443 1:CAS:528: DyaK1MXhslWjtbg%3D 10051526
19. CP Fenster JH Hicks ML Beckman PJ Covernton MW Quick RA Lester 1999 Desensitization of nicotinic receptors in the central nervous system Ann N Y Acad Sci 868 620 623 10.1111/j.1749-6632.1999.tb11335.x 1:CAS:528: DyaK1MXjvFKhsrg%3D 10414343 (Pubitemid 29281174)
20. CP Fenster TL Whitworth EB Sheffield MW Quick RA Lester 1999 Upregulation of surface alpha4beta2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine J Neurosci 19 4804 4814 1:CAS:528:DyaK1MXjvVCkurY%3D 10366615
21. MF Ferrari DR Fior-Chadi 2007 Chronic nicotine administration. Analysis of the development of hypertension and glutamatergic neurotransmission Brain Res Bull 72 215 224 10.1016/j.brainresbull.2006.09.013 1:CAS:528: DC%2BD2sXkslKksrk%3D 17452284 (Pubitemid 46604849)
22. MF Ferrari MK Raizada DR Fior-Chadi 2007 Nicotine modulates the renin-angiotensin system of cultured neurons and glial cells from cardiovascular brain areas of Wistar Kyoto and spontaneously hypertensive rats J Mol Neurosci 33 284 293 10.1007/s12031-007-9006-x 1:CAS:528:DC%2BD2sXhtlWitr3L 17952638 (Pubitemid 350242538)
23. MF Ferrari MK Raizada DR Fior-Chadi 2008 Differential regulation of the renin-angiotensin system by nicotine in WKY and SHR glia J Mol Neurosci 35 151 160 10.1007/s12031-007-9025-7 1:CAS:528:DC%2BD1cXmsFKjs7k%3D 18369742
24. MF Ferrari EM Reis JP Matsumoto DR Fior-Chadi 2009 Gene expression profiling of cultured cells from brainstem of newborn spontaneously hypertensive and Wistar Kyoto rats Cell Mol Neurobiol 29 3 287 308 10.1007/s10571-008-9321-y 1:CAS:528:DC%2BD1MXltVOmtLw%3D 18949554
25. MFR Ferrari EM Reis JPP Matsumoto DR Fior-Chadi 2010 Transcriptome analysis of nicotine-exposed cells from the brainstem of neonate spontaneously hypertensive and Wistar Kyoto rats Pharmacogenomics J 10 134 160 10.1038/tpj.2009.42 1:CAS:528:DC%2BD1MXhtFamt7rP 19752883
26. S Ferre I Diamond SR Goldberg L Yao SM Hourani ZL Huang Y Urade I Kitchen 2007 Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain Prog Neurobiol 83 332 347 10.1016/j.pneurobio.2007.04.002 1:CAS:528:DC%2BD2sXhtlags7zO 17532111 (Pubitemid 350110608)
27. K Fuxe S Ferre S Genedani R Franco LF Agnati 2007 Adenosine receptor-dopamine receptor interactions in the basal ganglia and their relevance for brain function Physiol Behav 92 210 217 10.1016/j.physbeh.2007.05.034 1:CAS:528:DC%2BD2sXhtVChu7nP 17572452 (Pubitemid 47381380)
28. JP Greenwood JB Stoker DA Mary 1999 Single-unit sympathetic discharge: quantitative assessment in human hypertensive disease Circulation 100 1305 1310 1:STN:280:DyaK1MvitlKiug%3D%3D 10491375
29. M Grilli M Parodi M Raiteri M Marchi 2005 Chronic nicotine differentially affects the function of nicotinic receptor subtypes regulating neurotransmitter release J Neurochem 93 1353 1360 10.1111/j.1471-4159.2005.03126.x 1:CAS:528:DC%2BD2MXltVansbg%3D 15934954 (Pubitemid 40776588)
30. O Grisk HJ Rose G Lorenz R Rettig 2002 Sympathetic-renal interaction in chronic arterial pressure control Am J Physiol Regul Integr Comp Physiol 283 441 450
31. 2+ and cAMP in nicotine-elicited elevation of tyrosine hydroxylase mRNA Am J Physiol 276 54 65
32. PG Guyenet 2006 The sympathetic control of blood pressure Nat Rev Neurosci 7 335 346 10.1038/nrn1902 1:CAS:528:DC%2BD28Xks1OjtLg%3D 16760914
33. A Haschemi O Wagner R Marculescu B Wegiel SC Robson N Gagliani D Gallo JF Chen FH Bach LE Otterbein 2007 Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages J Immunol 178 5921 5929 1:CAS:528:DC%2BD2sXktlWhsbo%3D 17442976
34. WY Ho PJ Lu M Hsiao HR Hwang YC Tseng MH Yen CJ Tseng 2008 Adenosine modulates cardiovascular functions through activation of extracellular signal-regulated kinases 1 and 2 and endothelial nitric oxide synthase in the nucleus tractus solitarii of rats Circulation 117 773 780 10.1161/ CIRCULATIONAHA.107.746032 1:CAS:528:DC%2BD1cXhsV2jsro%3D 18227383 (Pubitemid 351640678)
35. Y Inoue L Yao FW Hopf P Fan Z Jiang A Bonci I Diamond 2007 Nicotine and ethanol activate protein kinase A synergistically via G(i) betagamma subunits in nucleus accumbens/ventral tegmental cocultures: the role of dopamine D(1)/D(2) and adenosine A(2A) receptors J Pharmacol Exp Ther 322 23 29 10.1124/jpet.107.120675 1:CAS:528:DC%2BD2sXntl2jsbs%3D 17468300 (Pubitemid 46956347)
36. JK Kane O Konu JZ Ma MD Li 2004 Nicotine coregulates multiple pathways involved in protein modification/degradation in rat brain Brain Res Mol Brain Res 132 181 191 10.1016/j.molbrainres.2004.09.010 1:CAS:528:DC%2BD2cXhtVCktLnL 15582157 (Pubitemid 39586760)
37. BM Kivell FJ Mcdonald JH Miller 2001 Method for serum-free culture of late fetal and early postnatal rat brainstem neurons Brain Res Brain Res Protoc 6 91 99 10.1016/S1385-299X(00)00037-4 1:CAS:528:DC%2BD3MXht1yjsLY%3D 11223407 (Pubitemid 32167151)
38. MD Li JK Kane SL Parker K Mcallen SG Matta BM Sharp 2000 Nicotine administration enhances NPY expression in the rat hypothalamus Brain Res 867 157 164 10.1016/S0006-8993(00)02283-6 1:CAS:528:DC%2BD3cXjs1Grtb0%3D 10837809 (Pubitemid 30317392)
39. J Linden 2005 Adenosine in tissue protection and tissue regeneration Mol Pharmacol 67 1385 1397 10.1124/mol.105.011783 1:CAS:528:DC%2BD2MXktFegsL0%3D 15703375 (Pubitemid 40594134)
40. KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 25 402 408 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D 11846609 (Pubitemid 34164012)
41. WC Lo CR Jan SN Wu CJ Tseng 1998 Cardiovascular effects of nitric oxide and adenosine in the nucleus tractus solitarii of rats Hypertension 32 1034 1038 1:CAS:528:DyaK1MXitVWisw%3D%3D 9856969
42. LV Lopes RA Cunha JA Ribeiro 1999 Increase in the number, G protein coupling, and efficiency of facilitatory adenosine A2a receptor in limbic cortex, but not striatum, of aged rats J Neurochem 73 1733 1738 10.1046/j.1471-4159.1999.731733.x 1:CAS:528:DyaK1MXmtlOhtrg%3D 10501222 (Pubitemid 29440178)
43. SG Matta JD Valentine BM Sharp 1997 Nicotine activates NPY and catecholaminergic neurons in brainstem regions involved in ACTH secretion Brain Res 759 259 269 10.1016/S0006-8993(97)00266-7 1:CAS:528:DyaK2sXjslKnurs%3D 9221946 (Pubitemid 27286704)
44. R Mosqueda-Garcia CJ Tseng M Appalsamy C Beck D Robertson 1991 Cardiovascular excitatory effects of adenosine in the nucleus of the solitary tract Hypertension 18 494 502 1:CAS:528:DyaK3MXmslWhtr0%3D 1680812
45. C Mulle D Choquet H Korn JP Changeux 1992 Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation Neuron 8 135 143 10.1016/0896-6273(92)90115-T 1:CAS:528:DyaK38Xht1WlsLc%3D 1309647
46. C Mulle C Lena JP Changeux 1992 Potentiation of nicotinic receptor response by external calcium in rat central neurons Neuron 8 937 945 10.1016/0896-6273(92)90208-U 1:CAS:528:DyaK38Xks1enu74%3D 1586487
47. RA Neff J Humphrey M Mihalevich D Mendelowitz 1998 Nicotine enhances presynaptic and postsynaptic glutamatergic neurotransmission to activate cardiac parasympathetic neurons Circ Res 83 1241 1247 1:CAS:528:DyaK1MXitVSr 9851941
48. YM Pinto M Paul D Ganten 1998 Lessons from rat models of hypertension: from Goldblatt to genetic engineering Cardiovasc Res 39 77 88 10.1016/S0008-6363(98)00077-7 1:CAS:528:DyaK1cXkvFOrurw%3D 9764191 (Pubitemid 28322381)
49. O Puig R Tjian 2005 Transcriptional feedback control of insulin receptor by dFOXO/FOXO1 Genes Dev 19 2435 2446 10.1101/gad.1340505 1:CAS:528: DC%2BD2MXhtFOntLrL 16230533 (Pubitemid 41483691)
50. K Rezvani Y Teng D Shim M De Biasi 2007 Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity J Neurosci 27 10508 10519 10.1523/JNEUROSCI.3353-07.2007 1:CAS:528:DC%2BD2sXhtFGmt7fM 17898222 (Pubitemid 47501994)
51. TJ Scislo DS O'leary 2005 Purinergic mechanisms of the nucleus of the solitary tract and neural cardiovascular control Neurol Res 27 182 194 10.1179/016164105X21959 1:CAS:528:DC%2BD2MXjt1ajs7Y%3D 15829182 (Pubitemid 40388424)
52. TJ Scislo DS O'leary 2006 Vasopressin V1 receptors contribute to hemodynamic and sympathoinhibitory responses evoked by stimulation of adenosine A2a receptors in NTS Am J Physiol Heart Circ Physiol 290 1889 1898 10.1152/ajpheart.01030.2005
53. TJ Scislo N Tan DS O'leary 2005 Differential role of nitric oxide in regional sympathetic responses to stimulation of NTS A2a adenosine receptors Am J Physiol Heart Circ Physiol 288 638 649 10.1152/ajpheart.00857.2004 (Pubitemid 40139646)
54. AM Sebastiao JA Ribeiro 2000 Fine-tuning neuromodulation by adenosine Trends Pharmacol Sci 21 341 346 10.1016/S0165-6147(00)01517-0 1:CAS:528:DC%2BD3cXmtF2gtLs%3D 10973087 (Pubitemid 30649669)
55. P Seguela J Wadiche K Dineley-Miller JA Dani JW Patrick 1993 Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium J Neurosci 13 596 604 1:CAS:528:DyaK3sXitVKhsLY%3D 7678857
56. JM Seubert F Xu JP Graves JB Collins SO Sieber RS Paules DL Kroetz DC Zeldin 2005 Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats Am J Physiol Renal Physiol 289 F522 F561 10.1152/ajprenal.00354.2004 (Pubitemid 41208470)
57. DV Smith VV Uteshev 2008 Heterogeneity of nicotinic acetylcholine receptor expression in the caudal nucleus of the solitary tract Neuropharmacology 54 445 453 10.1016/j.neuropharm.2007.10.018 1:CAS:528:DC%2BD1cXpt1KnsA%3D%3D 18078963
58. AF Sved FJ Gordon 1994 Amino acids as central neurotransmitters in the baroreceptor reflex pathway News Physiol Sci 9 243 246 1:CAS:528: DyaK2MXjtV2nu74%3D
59. AF Sved S Ito JC Sved 2003 Brainstem mechanisms of hypertension: role of the rostral ventrolateral medulla Curr Hypertens Rep 5 262 268 10.1007/s11906-003-0030-0 12724060
60. T Thomas JH St Lambert MR Dashwood KM Spyer 2000 Localization and action of adenosine A2a receptors in regions of the brainstem important in cardiovascular control Neuroscience 95 513 518 10.1016/S0306-4522(99)00473-X 1:CAS:528:DyaK1MXnslGlsr0%3D 10658631
61. CJ Tseng I Biaggioni M Appalsamy D Robertson 1988 Purinergic receptors in the brainstem mediate hypotension and bradycardia Hypertension 11 191 197 1:CAS:528:DyaL1cXht1Gisrc%3D 3277913
62. ME Turner J Farkas J Dunmire D Ely A Milsted 2009 Which Sry locus is the hypertensive Y chromosome locus? Hypertension 53 430 435 10.1161/ HYPERTENSIONAHA.108.124131 1:CAS:528:DC%2BD1MXlvFWjtA%3D%3D 19075093
63. S Ueno S Kakehata N Akaike 1993 Nicotinic acetylcholine receptor in dissociated rat nucleus tractus solitarii neurons Neurosci Lett 149 15 18 10.1016/0304-3940(93)90336-J 1:CAS:528:DyaK3sXhsVSguro%3D 8469372 (Pubitemid 23022119)