Activation of purinergic receptor subtypes in the nucleus tractus solitarius elicits specific regional vascular response patterns

Journal of the Autonomic Nervous System

Volumn 59, Issue 3, 1996, Pages 113-124

  Barraco, Robin A ^a   O'Leary, Donal S ^a   Ergene, Erhan ^a   Scislo, Tadeusz J ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

A(2a) Adenosine (P1) purinoceptors; Baroreflex; Cardiovascular control; CGS 21680; Nucleus tractus solitarius; P(2x) Purinoceptors; Regional blood flow; , Methylene ATP

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; PURINE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; VASODILATATION;

EID: 0030570450     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1838(96)00014-8     Document Type: Article

References (43)

1. [1] Barnard, E.A., Burnstock, G. and Webb, T.E., G protein-coupled receptors for ATP and other nucleotides: a new receptor family, Trends Pharmacol. Sci., 15 (1994) 67-70.
2. [2] Barraco, R.A., Janusz, C.A., Polasek, P.M., Parizon, M. and Roberts, P.A., Cardiovascular effects of microinjections of adenosine into the nucleus tractus solitarius, Brain Res. Bull., 20 (1988) 129-132.
3. [3] Barraco, R.A. and Phillis, J.W., Subtypes of adenosine receptors in the brainstem mediate opposite blood pressure responses, Neuropharmacology, 30 (1991) 403-407.
4. [4] Barraco, R.A., El-Ridi, M.R., Ergene, E. and Phillis, J.W., Adenosine receptor subtypes in the brainstem mediate distinct cardiovascular response patterns, Brain Res. Bull., 26 (1991) 59-84.
5. [5] Barraco, R., El-Ridi, M., Ergene, E., Parizon, M. and Bradley, D., An atlas of the rat subpostremal nucleus tractus solitarius, Brain Res. Bull., 29 (1992) 703-765.
6. 2a receptors associated with norepinephrine release and their desensitization in the rat nucleus tractus solitarius, J. Neurochem., 65 (1995) 1604-1611.
7. 2-purinoceptors, J. Auton. Nerv. Syst., 28 (1989) 85-88.
8. [8] Brake, A.J., Wagenbach, M.J. and Julius, D., New structural motif for ligand-gated ion channels defined by an inotropic ATP receptor, Nature, 371 (1994) 519-523.
9. 2-purinoceptor?, Gen. Pharmacol., 16 (1985) 433-440.
10. 2a receptors on soma and central terminals of rat vagal afferent neurons, Brain Res., 652 (1994) 137-144.
11. [11] Ciriello, J., Hochstenbach, S.L. and Roder, S., Central projections of baroreceptor and chemoreceptor afferent fibers in the rat. In R. Barraco (Ed.), Nucleus of the Solitary Tract, CRC Press, Boca Raton, FL, 1994, pp. 35-50.
12. [12] Dalziel, H.H. and Westfall, D.P., Receptors for adenine nucleotides and nucleosides: Subclassification, distribution and molecular characterization, Pharmacol. Rev., 46 (1994) 449-466.
13. [13] Dampney, R.A.L., Functional organization of central pathways regulating the cardiovascular system, Physiol. Rev., 74 (1994) 323-364.
14. [14] Edwards, F.A., Gibb, A.J. and Colquhoun, D., ATP receptor-mediated synaptic currents in the central nervous system, Nature, 359 (1992) 144-147.
15. [15] Evans, R.J., Derkach, V. and Surprenant, A., ATP mediates fast synaptic transmission in mammalian neurons, Nature, 357 (1992) 503-505.
16. 2-purinoceptors in the nucleus tractus solitarius mediate depressor responses, Neurosci. Lett., 174 (1994) 188-192.
17. [17] Fredholm, B.B., Abbracchio, M.P., Burnstock, G., Daly, J.W., Harlen, T.K., Jacobson, K.A., Leff, P. and Williams, M., Nomenclature and classification of purinoceptors, Pharmacol. Rev., 46 (1994) 143-156.
18. [18] Hashim, M.A. and Tadepalli, A.S., Hemodynamic responses evoked by endothelin from central cardiovascular neural substrates, Am. J. Physiol., 262 (1992) H1-H9.
19. [19] Haugland, R.P., Cationic membrane tracers: Dil, DiO and DiA. In K.D. Larison (Ed.), Handbook of Fluorescent Probes and Research Chemicals, 5th Edition, Molecular Probes, Oregon, 1992, 1-4.
20. [20] Inoue, K., Nakazawa, K., Fujimori, K., Watano, T. and Takanaka, A., Extracellular adenosine 5′-triphosphate-evoked glutamate release in cultured hipocampal neurons, Neurosci. Lett., 134 (1992) 215-218.
21. [21] Kendrick, E., Oberg, B. and Wennergren, G., Vasoconstrictor fibre discharge to skeletal muscle, kidney, intestine and skin at varying levels of arterial baroreceptor activity in the cat, Acta Physiol. Scand., 85 (1972) 464-476.
22. [22] Loewy, A.D., Central autonomic pathways. In A.D. Loewy and K.M. Spyer, (Eds.), Central Regulation of Autonomic Function, Oxford Press, New York, 1990, pp. 88-103.
23. [23] Longhurst, J.C., Reflex effects from abdominal visceral afferents. In I.H. Zucker and J.P. Gilmore (Eds.), Reflex Control of Circulation, CRC Press, Boca Raton, FL, 1991, pp. 551-577.
24. [24] Mallard, N., Marshall, R., Sithers, A. and Spriggs, B., Suramin: a selective inhibitor of purinergic neurotransmission in the rat isolated vas deferens, Eur. J. Pharmacol., 220 (1992) 1-10.
25. [25] McKirnan, M.D., Gray, C.G. and White, F.C., Effects of feeding on muscle blood flow during prolonged exercise in miniature swine, J. Appl. Physiol., 70 (1991) 1097-1104.
26. [26] Menetrey, D. and Basbaum, A.I., Spinal and trigeminal projections to the nucleus of the solitary tract: a possible substrate for somatovisceral and viscerovisceral reflex activation, J. Comp. Neurol., 255 (1987) 439-450.
27. [27] Mosqueda-Garcia, R., Tseng, C.J., Appalsamy, M., Beck, C. and Robertson, D., Cardiovascular excitatory effects of adenosine in the nucleus of the solitary tract, Hypertension, 18 (1991) 494-502.
28. [28] Norris, C.P., Barnes, G.E., Smith, E.E. and Granger, H.J., Autoregulation of superior mesenteric flow in fasted and fed dogs, Am. J. Physiol., 237 (1979) H174-H177.
29. [29] O'Leary, D.S., Regional vascular resistance vs. conductance: which index for baroreflex responses?, Am. J. Physiol., 260 (1991) H632-H637.
30. [30] O'Leary, D.S. and Sheriff, D.D., Is the muscle metaboreflex important in control of blood flow to ischemic active skeletal muscle in dogs?, Am. J. Physiol., 268 (1995) H980-H986.
31. [31] Onai, T., Saji, M. and Miura, M., Functional subdivisions of the nucleus tractus solitarii of the rats as determined by circulatory and respiratory responses to electrical stimulation of the nucleus, J. Auton. Nerv. Syst., 21 (1987) 195-202.
32. [32] Ruggiero, D.A., Pickel, V.M., Milner, T.A., Anwar, M., Otake, K., Mtui, E.P. and Park, D., Viscerosensory processing in nucleus tractus solitarii: structural and neurochemical substrates. In R. Barraco (Ed.), Nucleus of the Solitary Tract, CRC Press, Boca Raton, FL, 1994, pp. 3-34.
33. [33] Sagawa, K., Baroreflex control of systemic arterial pressure and vascular bed. In J.T. Shepeherd and F.M. Abboud (Eds.), Handbook of Physiology, Section 2: The Cardiovascular System, Vol III; Peripheral Circulation and Organ Blood Flow, Part 2. Am. Physiological Society, Bethesda, 1983, pp. 453-498.
34. 2-purinoceptors in the nucleus tractus solitarius (NTS) abolishes baroreflex regulation of heart rate. FASEB J., 9 (1995) A44 (Abstract).
35. [35] Snyder, D.W., Doba, N. and Reis, D.J., Regional distribution of blood flow during arterial hypertension produced by lesions of the nucleus tractus solitarii in rats, Circ. Res., 42 (1977) 87-91.
36. [36] Spyer, K.M., Modulation of NTS function by multiple descending inputs: An overview. In R. Barraco (Ed.), Nucleus of the Solitary Tract, CRC Press, Boca Raton, FL, 1994, pp. 161-167.
37. [37] Tao, S. and Abdel-Rahman, A. A., Neuronal and cardiovascular responses to adenosine microinjection into the nucleus tractus solitarius, Brain Res. Bull., 32 (1993) 407-417.
38. [38] Toney, G.M. and Mifflin, S.W., Time-dependent inhibition of hindlimb somatic afferent inputs to nucleus tractus solitarius, J. Neurophysiol., 72 (1994) 63-71.
39. + conductance in dissociated rat nucleus solitarii neurons, Brain Res., 597 (1992) 176-179.
40. 2x receptor for extracellular ATP, Nature, 371 (1994) 516-519.
41. [41] van Giersbergen, P.L.M., Palkovitz, M. and De Jong, W., Involvement of neurotransmitters in the nucleus tractus solitarii in cardiovascular regulation, Physiol. Rev., 72 (1992) 789-824.
42. [42] von Kügelgen, I. and Starke, K., Noradrenaline-ATP co-transmission in the sympathetic nervous system, Trends Pharmacol. Sci., 12 (1991) 319-324.
43. [43] Zimmermann, H., Signalling via ATP in the nervous system, Trends Neurosci., 17 (1994) 420-426.