메뉴 건너뛰기




Volumn 193, Issue 9, 2009, Pages 2017-2034

Role of epithelial-mesenchymal transition in tumor progression;Rôle de la transition épithélio-mésenchymateuse au cours de la progression tumorale

Author keywords

Aging; Apoptosis; Neoplasm metastasis; Neoplasms

Indexed keywords


EID: 77954529686     PISSN: 00014079     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0001-4079(19)32376-3     Document Type: Article
Times cited : (12)

References (50)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • HANAHAN D., WEINBERG R.A. - The hallmarks of cancer. Cell, 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • FOLKMAN J. - Tumor angiogenesis: therapeutic implications. N. Engl. J. Med., 1971, 285, 1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 4
    • 0032544686 scopus 로고    scopus 로고
    • Tumor induction of VEGF promoter activity in stromal cells
    • FUKUMURA D., XAVIER R., SUGIURA T. et al. - Tumor induction of VEGF promoter activity in stromal cells. Cell, 1998, 94, 715-725.
    • (1998) Cell , vol.94 , pp. 715-725
    • Fukumura, D.1    Xavier, R.2    Sugiura, T.3
  • 5
  • 6
    • 73349131112 scopus 로고    scopus 로고
    • Micrometastatic disease and metastatic outgrowth: Clinical issues and experimental approaches
    • MCGOWAN P.M., KIRSTEIN J.M., CHAMBERS A.F. - Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches. Future Oncol., 2009, 5, 1083-1098.
    • (2009) Future Oncol. , vol.5 , pp. 1083-1098
    • Mcgowan, P.M.1    Kirstein, J.M.2    Chambers, A.F.3
  • 7
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • THIERY J.P., SLEEMAN J.P. - Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell. Biol., 2006, 7, 131-142.
    • (2006) Nat. Rev. Mol. Cell. Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 8
    • 56849121006 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition during gastrulation: An embryological view
    • NAKAYA Y., SHENG G. - Epithelial to mesenchymal transition during gastrulation: an embryological view. Dev. Growth Differ.. 2008, 50, 755-766.
    • (2008) Dev. Growth Differ.. , vol.50 , pp. 755-766
    • Nakaya, Y.1    Sheng, G.2
  • 9
    • 0036322007 scopus 로고    scopus 로고
    • Evidence that fibroblasts derive from epithelium during tissue fibrosis
    • IWANO M., PLIETH D., DANOFF T.M. et al. - Evidence that fibroblasts derive from epithelium during tissue fibrosis. J. Clin. Invest., 2002, 110, 341-350.
    • (2002) J. Clin. Invest. , vol.110 , pp. 341-350
    • Iwano, M.1    Plieth, D.2    Danoff, T.M.3
  • 10
    • 36348994426 scopus 로고    scopus 로고
    • Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer
    • BERX G., RASPE E., CHRISTOFORI G. - Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin. Exp. Metastasis, 2007, 24, 587-597.
    • (2007) Clin. Exp. Metastasis , vol.24 , pp. 587-597
    • Berx, G.1    Raspe, E.2    Christofori, G.3
  • 11
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • ZAVADIL J., BOTTINGER E.P. - TGF-beta and epithelial-to-mesenchymal transitions. Oncogene, 2005, 24, 5764-5774.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 12
    • 0038756636 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions
    • PEINADO H., QUINTANILLA M., CANO A. - Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem., 2003, 278, 21113-21123.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21113-21123
    • Peinado, H.1    Quintanilla, M.2    Cano, A.3
  • 13
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • DOI 10.1146/annurev.cellbio.20.010403.113126
    • LOGAN C.Y., NUSSE R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell. Dev. Biol., 2004, 20, 781-810. (Pubitemid 39488658)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 14
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • PEINADO H., OLMEDA D., CANO A. - Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer, 2007, 7, 415-428.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 15
    • 57349164238 scopus 로고    scopus 로고
    • Redox mechanisms switch on hypoxiadependent epithelial-mesenchymal transition in cancer cells
    • CANNITO S, NOVO E, COMPAGNONE A, et al. - Redox mechanisms switch on hypoxiadependent epithelial-mesenchymal transition in cancer cells. Carcinogenesis, 2008, 29, 2267-2278.
    • (2008) Carcinogenesis , vol.29 , pp. 2267-2278
    • Cannito, S.1    Novo, E.2    Compagnone, A.3
  • 16
    • 40249113328 scopus 로고    scopus 로고
    • Direct regulation of TWIST by HIF-lalpha promotes metastasis
    • YANG M.H., Wu M.Z., Cmou S.H., et al. - Direct regulation of TWIST by HIF-lalpha promotes metastasis. Nat. Cell. Biol., 2008, 10, 295-305.
    • (2008) Nat. Cell. Biol. , vol.10 , pp. 295-305
    • Yang, M.H.1    Wu, M.Z.2    Cmou, S.H.3
  • 18
    • 45849087087 scopus 로고    scopus 로고
    • Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence
    • ANSIEAU S., BASTED J., DOREAU A. et al. - Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell, 2008 ; 14,79-89.
    • (2008) Cancer Cell , vol.14 , pp. 79-89
    • Ansieau, S.1    Basted, J.2    Doreau, A.3
  • 19
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
    • YANG J., WEINBERG R.A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell, 2008, 14, 818-829. (Pubitemid 351757205)
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 20
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • YANG J., MANI S.A., DONAHER J.L. et al. - Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell, 2004, 117, 927-939.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3
  • 21
    • 68249162521 scopus 로고    scopus 로고
    • Twist expression promotes migration and invasion in hepatocellular carcinoma
    • MATSUO N., SHIRAHA H., FUJIKAWA T. et al. - Twist expression promotes migration and invasion in hepatocellular carcinoma. BMC Cancer, 2009, 9, 240.
    • (2009) BMC Cancer , vol.9 , pp. 240
    • Matsuo, N.1    Shiraha, H.2    Fujikawa, T.3
  • 22
    • 0027530351 scopus 로고
    • Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis
    • OKA H., SHIOZAKI H., KOBAYASHI K. et al. - Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res., 1993, 53, 1696-1701.
    • (1993) Cancer Res. , vol.53 , pp. 1696-1701
    • Oka, H.1    Shiozaki, H.2    Kobayashi, K.3
  • 23
    • 0035215429 scopus 로고    scopus 로고
    • Expression of E-cadherin and lymph node metastasis in resected non-small-cell lung cancer
    • HIRATA T., FUKUSE T., NAIKI H. et al. Expression of E-cadherin and lymph node metastasis in resected non-small-cell lung cancer. Clin. Lung Cancer, 2001, 3, 134-140. (Pubitemid 33138778)
    • (2001) Clinical Lung Cancer , vol.3 , Issue.2 , pp. 134-140
    • Hirata, T.1    Fukuse, T.2    Naiki, H.3    Wada, H.4
  • 24
    • 12244290974 scopus 로고    scopus 로고
    • Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis
    • KAMARA T., KUSAKA T., Nism M. et al. - Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis. J. Exp. Clin. Cancer Res., 2003, 22, 117-123.
    • (2003) J. Exp. Clin. Cancer Res. , vol.22 , pp. 117-123
    • Kamara, T.1    Kusaka, T.2    Nism, M.3
  • 25
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • ONDER T.T., GUPTA P.B., MANI S.A. et al. - Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008, 68, 3645-3654.
    • (2008) Cancer Res. , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3
  • 26
    • 22244473343 scopus 로고    scopus 로고
    • The fallacy of epithelial mesenchymal transition in neoplasia
    • DOI 10.1158/0008-5472.CAN-05-0699
    • TARIN D., THOMPSON E.W., NEWGREEN D.F. The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res., 2005, 65, 5996-6000. (Pubitemid 40994379)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 5996-6000
    • Tarin, D.1
  • 27
    • 33748116186 scopus 로고    scopus 로고
    • A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
    • SPADERNA S., SCHMALHOFER O., HLUBEK F. et al. - A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology, 2006, 131, 830-840.
    • (2006) Gastroenterology , vol.131 , pp. 830-840
    • Spaderna, S.1    Schmalhofer, O.2    Hlubek, F.3
  • 29
    • 9244224723 scopus 로고    scopus 로고
    • Intrinsic tumour suppression
    • LOWE S.W., CEPERO E., EVAN G. - Intrinsic tumour suppression. Nature. 2004, 432, 307-315.
    • (2004) Nature , vol.432 , pp. 307-315
    • Lowe, S.W.1    Cepero, E.2    Evan, G.3
  • 31
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • EVAN G.I., WYLLIE A.H., GILBERT C.S. et al. - Induction of apoptosis in fibroblasts by c-myc protein. Cell, 1992, 69, 119-128.
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1    Wyllie, A.H.2    Gilbert, C.S.3
  • 32
    • 0033569422 scopus 로고    scopus 로고
    • Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
    • EISCHEN C.M., WEBER J.D., ROUSSEL M.F. - Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev., 1999, 13, 2658-2669.
    • (1999) Genes Dev. , vol.13 , pp. 2658-2669
    • Eischen, C.M.1    Weber, J.D.2    Roussel, M.F.3
  • 33
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • SERRANO M., LIN A.W., MCCURRACH M.E. et al. - Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 1997, 88, 593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    Mccurrach, M.E.3
  • 34
    • 10944221249 scopus 로고    scopus 로고
    • Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells
    • VALSESIA-WITTMANN S., MAGDELEINE M., DUPASQUIER S. et al. - Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells. Cancer Cell, 2004, 6, 625-630.
    • (2004) Cancer Cell , vol.6 , pp. 625-630
    • Valsesia-Wittmann, S.1    Magdeleine, M.2    Dupasquier, S.3
  • 35
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • BRODEUR G.M., SEEGER R.C., SCHWAB M. et al. - Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science, 1984, 224, 1121-1124.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3
  • 36
    • 0033200349 scopus 로고    scopus 로고
    • Twist is a potential oncogene that inhibits apoptosis
    • MAESTRO R., DEI Tos A.P., HAMAMORI Y. et al. - Twist is a potential oncogene that inhibits apoptosis. Genes Dev., 1999, 13, 2207-2217.
    • (1999) Genes Dev. , vol.13 , pp. 2207-2217
    • Maestro, R.1    Dei Tos, A.P.2    Hamamori, Y.3
  • 37
    • 12544249159 scopus 로고    scopus 로고
    • HOXA5-twist interaction alters p53 homeostasis in breast cancer cells
    • STASINOPOULOS I.A., MIRONCHIK Y., RAMAN A. el al. - HOXA5-twist interaction alters p53 homeostasis in breast cancer cells. J. Biol Chem., 2005, 280, 2294-2299.
    • (2005) J. Biol Chem. , vol.280 , pp. 2294-2299
    • Stasinopoulos, I.A.1    Mironchik, Y.2    Raman, A.3
  • 38
    • 52149111636 scopus 로고    scopus 로고
    • Twist and p53 reciprocally regulate target genes via direct interaction
    • SHIOTA M., IZUMI H., ONITSUKA T. et al. - Twist and p53 reciprocally regulate target genes via direct interaction. Oncogene, 2008.
    • (2008) Oncogene
    • Shiota, M.1    Izumi, H.2    Onitsuka, T.3
  • 39
    • 17244366865 scopus 로고    scopus 로고
    • Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
    • GORGOULIS V.G., VASSILIOU L.V., KARAKAIDOS P. et al. - Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature, 2005, 434, 907-913.
    • (2005) Nature , vol.434 , pp. 907-913
    • Gorgoulis, V.G.1    Vassiliou, L.V.2    Karakaidos, P.3
  • 40
    • 33845235459 scopus 로고    scopus 로고
    • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
    • BARTKOVA J., REZAEI N., LIONTOS M. et al. - Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature, 2006, 444, 633-637.
    • (2006) Nature , vol.444 , pp. 633-637
    • Bartkova, J.1    Rezaei, N.2    Liontos, M.3
  • 41
    • 23244447893 scopus 로고    scopus 로고
    • Tumour biology: Senescence in premalignant tumours
    • COLLADO M., GIL J., EFEYAN A. et al. - Tumour biology: senescence in premalignant tumours. Nature, 2005, 436, 642.
    • (2005) Nature , vol.436 , pp. 642
    • Collado, M.1    Gil, J.2    Efeyan, A.3
  • 42
    • 34247897276 scopus 로고    scopus 로고
    • A. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
    • SARKISIAN C.J., KEISTER B.A., STAIRS D.B. et al. - A. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nat. Cell. Biol. 2007, 9, 493-505.
    • (2007) Nat. Cell. Biol. , vol.9 , pp. 493-505
    • Sarkisian, C.J.1    Keister, B.A.2    Stairs, D.B.3
  • 44
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • CHEN Z., TROTMAN L.C., SHAFFER D. et al. - Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 2005, 436, 725-730.
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1    Trotman, L.C.2    Shaffer, D.3
  • 46
    • 69349094006 scopus 로고    scopus 로고
    • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
    • MARION R.M., STRATI K., LI H. et al. - A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature, 2009, 460, 1149-1153.
    • (2009) Nature , vol.460 , pp. 1149-1153
    • Marion, R.M.1    Strati, K.2    Li, H.3
  • 47
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • MOREL A.P., LIEVRE M., THOMAS C et al. - Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE, 2008, 3, e2888.
    • (2008) PLoS ONE , vol.3
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3
  • 49
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • CRHGHTON C.J., LI X., LANDIS M. et al. - Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc. Natl. Acad. Sci. U S A. 2009, 106, 13820-13825.
    • (2009) Proc. Natl. Acad. Sci. U S A. , vol.106 , pp. 13820-13825
    • Crhghton, C.J.1    Li, X.2    Landis, M.3
  • 50
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • GUPTA P.B., ONDER T.T., JIANG G. et al. - Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell., 2009, 138, 645-659.
    • (2009) Cell. , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.