-
1
-
-
0015338405
-
The origin of the equine endometrial cups. I. Production of PMSG by fetal trophoblast cells
-
Allen WR, Moor RM 1972 The origin of the equine endometrial cups. I. Production of PMSG by fetal trophoblast cells. J Reprod Fertil 29:313-316
-
(1972)
J Reprod Fertil
, vol.29
, pp. 313-316
-
-
Allen, W.R.1
Moor, R.M.2
-
2
-
-
0016228403
-
Chemical and biological properties of the subunits of pregnant mare serum gonadotropin
-
Papkoff H 1974 Chemical and biological properties of the subunits of pregnant mare serum gonadotropin. Biochem Biophys Res Commun 58:397-404
-
(1974)
Biochem Biophys Res Commun
, vol.58
, pp. 397-404
-
-
Papkoff, H.1
-
3
-
-
0018764369
-
Pregnant mare serum gonadotropin. Purification and physicochemical, biological, and immunological characterization
-
Christakos S, Bahl OP 1979 Pregnant mare serum gonadotropin. Purification and physicochemical, biological, and immunological characterization. J Biol Chem 254:4253-4261
-
(1979)
J Biol Chem
, vol.254
, pp. 4253-4261
-
-
Christakos, S.1
Bahl, O.P.2
-
4
-
-
0003527224
-
Studies on the rate of disapearance and fate of mare gonadotropic hormone following intravenous injection
-
Catchpole HR, Cole HH, Pearson PB 1935 Studies on the rate of disapearance and fate of mare gonadotropic hormone following intravenous injection. Am J Physiol 112:21-26
-
(1935)
Am J Physiol
, vol.112
, pp. 21-26
-
-
Catchpole, H.R.1
Cole, H.H.2
Pearson, P.B.3
-
5
-
-
0016731993
-
Pregnant mare serum gonadotrophin: Rate of clearance from the circulation of sheep
-
McIntosh JE, Moor RM, Allen WR 1975 Pregnant mare serum gonadotrophin: rate of clearance from the circulation of sheep. J Reprod Fertil 44:95-100
-
(1975)
J Reprod Fertil
, vol.44
, pp. 95-100
-
-
McIntosh, J.E.1
Moor, R.M.2
Allen, W.R.3
-
6
-
-
0025020754
-
The biological role of the carboxyl-terminal extension of human chorionic gonadotropin [corrected] β-subunit
-
Matzuk MM, Hsueh AJ, Lapolt P, Tsafriri A, Keene JL, Boime I 1990 The biological role of the carboxyl-terminal extension of human chorionic gonadotropin [corrected] β-subunit. Endocrinology 126:376-383
-
(1990)
Endocrinology
, vol.126
, pp. 376-383
-
-
Matzuk, M.M.1
Hsueh, A.J.2
Lapolt, P.3
Tsafriri, A.4
Keene, J.L.5
Boime, I.6
-
7
-
-
0020696389
-
Purification of equine gonadotropins and comparative study of their acid-dissociation and receptor-binding specificity
-
Guillou F, Combarnous Y 1983 Purification of equine gonadotropins and comparative study of their acid-dissociation and receptor-binding specificity. Biochim Biophys Acta 755:229-236
-
(1983)
Biochim Biophys Acta
, vol.755
, pp. 229-236
-
-
Guillou, F.1
Combarnous, Y.2
-
8
-
-
0021690978
-
Comparison of in vitro follicle-stimulating hormone (FSH) activity of equine gonadotropins (luteinizing hormone, FSH, and chorionic gonadotropin) in male and female rats
-
Combarnous Y, Guillou F, Martinat N 1984 Comparison of in vitro follicle-stimulating hormone (FSH) activity of equine gonadotropins (luteinizing hormone, FSH, and chorionic gonadotropin) in male and female rats. Endocrinology 115:1821-1827
-
(1984)
Endocrinology
, vol.115
, pp. 1821-1827
-
-
Combarnous, Y.1
Guillou, F.2
Martinat, N.3
-
9
-
-
0018139239
-
Pregnant mare serum gonadotropin exhibits higher affinity for lutropin than for follitropin receptors of porcine testis
-
Combarnous Y, Hennen G, Ketelslegers JM 1978 Pregnant mare serum gonadotropin exhibits higher affinity for lutropin than for follitropin receptors of porcine testis. FEBS Lett 90:65-68
-
(1978)
FEBS Lett
, vol.90
, pp. 65-68
-
-
Combarnous, Y.1
Hennen, G.2
Ketelslegers, J.M.3
-
10
-
-
0018669494
-
Biological and binding activities of equine pituitary gonadotrophins and pregnant mare serum gonadotrophin
-
Licht P, Gallo AB, Aggarwal BB, Farmer SW, Castelino JB, Papkoff H 1979 Biological and binding activities of equine pituitary gonadotrophins and pregnant mare serum gonadotrophin. J Endocrinol 83:311-322
-
(1979)
J Endocrinol
, vol.83
, pp. 311-322
-
-
Licht, P.1
Gallo, A.B.2
Aggarwal, B.B.3
Farmer, S.W.4
Castelino, J.B.5
Papkoff, H.6
-
11
-
-
0033056913
-
Humoral immune response to equine chorionic gonadotropin in ewes: Association with major histocompatibility complex and interference with subsequent fertility
-
DOI 10.1095/biolreprod61.1.209
-
Roy F, Combes B, Vaiman D, Cribiu EP, Pobel T, Delétang F, Combarnous Y, Guillou F, Maurel MC 1999 Humoral immune response to equine chorionic gonadotropin in ewes: association with major histocompatibility complex and interference with subsequent fertility. Biol Reprod 61:209-218 (Pubitemid 29295987)
-
(1999)
Biology of Reproduction
, vol.61
, Issue.1
, pp. 209-218
-
-
Roy, F.1
Combes, B.2
Vaiman, D.3
Cribiu, E.P.4
Pobel, T.5
Deletang, F.6
Combarnous, Y.7
Guillou, F.8
Maurel, M.-C.9
-
12
-
-
0033022377
-
The negative effect of repeated equine chorionic gonadotropin treatment on subsequent fertility in Alpine goats is due to a humoralimmuneresponse involving the major histocompatibility complex
-
Roy F, Maurel MC, Combes B, Vaiman D, Cribiu EP, Lantier I, Pobel T, Delétang F, Combarnous Y, Guillou F 1999 The negative effect of repeated equine chorionic gonadotropin treatment on subsequent fertility in Alpine goats is due to a humoralimmuneresponse involving the major histocompatibility complex. Biol Reprod 60:805-813
-
(1999)
Biol Reprod
, vol.60
, pp. 805-813
-
-
Roy, F.1
Maurel, M.C.2
Combes, B.3
Vaiman, D.4
Cribiu, E.P.5
Lantier, I.6
Pobel, T.7
Delétang, F.8
Combarnous, Y.9
Guillou, F.10
-
13
-
-
0021823827
-
Rapid in vitro desensitization of the testosterone response in rat Leydig cells by subactive concentrations of porcine luteinizing hormone
-
Guillou F, Martinat N, Combarnous Y 1985 Rapid in vitro desensitization of the testosterone response in rat Leydig cells by subactive concentrations of porcine luteinizing hormone. FEBS Lett 184:6-9
-
(1985)
FEBS Lett
, vol.184
, pp. 6-9
-
-
Guillou, F.1
Martinat, N.2
Combarnous, Y.3
-
14
-
-
0026800702
-
The cloning of the human follicle stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells
-
Kelton CA, Cheng SV, Nugent NP, Schweickhardt RL, Rosenthal JL, Overton SA, Wands GD, Kuzeja JB, Luchette CA, Chappel SC 1992 The cloning of the human follicle stimulating hormone receptor and its expression in COS-7, CHO, and Y-1 cells. Mol Cell Endocrinol 89:141-151
-
(1992)
Mol Cell Endocrinol
, vol.89
, pp. 141-151
-
-
Kelton, C.A.1
Cheng, S.V.2
Nugent, N.P.3
Schweickhardt, R.L.4
Rosenthal, J.L.5
Overton, S.A.6
Wands, G.D.7
Kuzeja, J.B.8
Luchette, C.A.9
Chappel, S.C.10
-
15
-
-
0345827711
-
Antiequine chorionic gonadotropin (eCG) antibodies generated in goats treated with eCG for the induction of ovulation modulate the luteinizing hormone and follicle-stimulating hormone bioactivities of eCG differently
-
Hervé V, Roy F, Bertin J, Guillou F, Maurel MC 2004 Antiequine chorionic gonadotropin (eCG) antibodies generated in goats treated with eCG for the induction of ovulation modulate the luteinizing hormone and follicle-stimulating hormone bioactivities of eCG differently. Endocrinology 145:294-303
-
(2004)
Endocrinology
, vol.145
, pp. 294-303
-
-
Hervé, V.1
Roy, F.2
Bertin, J.3
Guillou, F.4
Maurel, M.C.5
-
16
-
-
0031041426
-
Enhancement of FSH bioactivity in vivo using site-specific antisera
-
Ferasin L, Gabai G, Beattie J, Bono G, Holder AT 1997 Enhancement of FSH bioactivity in vivo using site-specific antisera. J Endocrinol 152:355-363
-
(1997)
J Endocrinol
, vol.152
, pp. 355-363
-
-
Ferasin, L.1
Gabai, G.2
Beattie, J.3
Bono, G.4
Holder, A.T.5
-
17
-
-
0027208893
-
Monoclonal antibody enhancement of FSH-induced uterine growth in snell dwarf mice
-
Glencross RG, Lovell RD, Holder AT 1993 Monoclonal antibody enhancement of FSH-induced uterine growth in snell dwarf mice. J Endocrinol 136:R5-R7
-
(1993)
J Endocrinol
, vol.136
-
-
Glencross, R.G.1
Lovell, R.D.2
Holder, A.T.3
-
18
-
-
0022343939
-
Monoclonal antibody-mediated enhancement of growth hormone activity in vivo
-
Holder AT, Aston R, Preece MA, Ivanyi J 1985 Monoclonal antibody-mediated enhancement of growth hormone activity in vivo. J Endocrinol 107:R9-R12
-
(1985)
J Endocrinol
, vol.107
-
-
Holder, A.T.1
Aston, R.2
Preece, M.A.3
Ivanyi, J.4
-
19
-
-
0025646717
-
Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity
-
Xie YB, Wang H, Segaloff DL 1990 Extracellular domain of lutropin/choriogonadotropin receptor expressed in transfected cells binds choriogonadotropin with high affinity. J Biol Chem 265:21411-21414
-
(1990)
J Biol Chem
, vol.265
, pp. 21411-21414
-
-
Xie, Y.B.1
Wang, H.2
Segaloff, D.L.3
-
20
-
-
0023155281
-
Monoclonal antibodies can enhance the biological activity of thyrotropin
-
Holder AT, Aston R, Rest JR, Hill DJ, Patel N, Ivanyi J 1987 Monoclonal antibodies can enhance the biological activity of thyrotropin. Endocrinology 120:567-573
-
(1987)
Endocrinology
, vol.120
, pp. 567-573
-
-
Holder, A.T.1
Aston, R.2
Rest, J.R.3
Hill, D.J.4
Patel, N.5
Ivanyi, J.6
-
21
-
-
0023100491
-
Enhancement of bovine growth hormone activity in vivo by monoclonal antibodies
-
Aston R, Holder AT, Ivanyi J, Bomford R 1987 Enhancement of bovine growth hormone activity in vivo by monoclonal antibodies. Mol Immunol 24:143-150
-
(1987)
Mol Immunol
, vol.24
, pp. 143-150
-
-
Aston, R.1
Holder, A.T.2
Ivanyi, J.3
Bomford, R.4
-
22
-
-
0024586465
-
Potentiation of growth hormone activity in sheep using monoclonal antibodies
-
Pell JM, Johnsson ID, Pullar RA, Morrell DJ, Hart IC, Holder AT, Aston R 1989 Potentiation of growth hormone activity in sheep using monoclonal antibodies. J Endocrinol 120:R15-R18
-
(1989)
J Endocrinol
, vol.120
-
-
Pell, J.M.1
Johnsson, I.D.2
Pullar, R.A.3
Morrell, D.J.4
Hart, I.C.5
Holder, A.T.6
Aston, R.7
-
23
-
-
33845339257
-
Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease
-
Boyman O, Surh CD, Sprent J 2006 Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease. Expert Opin Biol Ther 6:1323-1331
-
(2006)
Expert Opin Biol Ther
, vol.6
, pp. 1323-1331
-
-
Boyman, O.1
Surh, C.D.2
Sprent, J.3
-
24
-
-
47249097468
-
IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T cell expansion without lymphopenia
-
Boyman O, Ramsey C, Kim DM, Sprent J, Surh CD 2008 IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T cell expansion without lymphopenia. J Immunol 180:7265-7275
-
(2008)
J Immunol
, vol.180
, pp. 7265-7275
-
-
Boyman, O.1
Ramsey, C.2
Kim, D.M.3
Sprent, J.4
Surh, C.D.5
-
25
-
-
33751509646
-
Aphosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for β-arrestin-mediated ERK activation
-
Kara E, Crépieux P, Gauthier C, Martinat N, Piketty V, Guillou F, Reiter E 2006 Aphosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for β-arrestin-mediated ERK activation. Mol Endocrinol 20:3014-3026
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3014-3026
-
-
Kara, E.1
Crépieux, P.2
Gauthier, C.3
Martinat, N.4
Piketty, V.5
Guillou, F.6
Reiter, E.7
-
26
-
-
41949089470
-
β-Arrestin-biased agonism at the β 2-adrenergic receptor
-
Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ 2008 β-Arrestin-biased agonism at the β 2-adrenergic receptor. J Biol Chem 283:5669-5676
-
(2008)
J Biol Chem
, vol.283
, pp. 5669-5676
-
-
Drake, M.T.1
Violin, J.D.2
Whalen, E.J.3
Wisler, J.W.4
Shenoy, S.K.5
Lefkowitz, R.J.6
-
27
-
-
0141593597
-
β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
-
Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G 2003 β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proc Natl Acad Sci USA 100:11406-11411
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11406-11411
-
-
Azzi, M.1
Charest, P.G.2
Angers, S.3
Rousseau, G.4
Kohout, T.5
Bouvier, M.6
Piñeyro, G.7
-
28
-
-
33744957160
-
Distinct β-arrestin- And G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
-
Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, Wang S, Eckhardt AE, Cowan CL, Spurney RF, Luttrell LM, Lefkowitz RJ 2006 Distinct β-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J Biol Chem 281:10856-10864
-
(2006)
J Biol Chem
, vol.281
, pp. 10856-10864
-
-
Gesty-Palmer, D.1
Chen, M.2
Reiter, E.3
Ahn, S.4
Nelson, C.D.5
Wang, S.6
Eckhardt, A.E.7
Cowan, C.L.8
Spurney, R.F.9
Luttrell, L.M.10
Lefkowitz, R.J.11
-
29
-
-
0141703263
-
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
-
Wei H, Ahn S, Shenoy SK, Karnik SS, Hunyady L, Luttrell LM, Lefkowitz RJ 2003 Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc Natl Acad Sci USA 100:10782-10787
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10782-10787
-
-
Wei, H.1
Ahn, S.2
Shenoy, S.K.3
Karnik, S.S.4
Hunyady, L.5
Luttrell, L.M.6
Lefkowitz, R.J.7
-
30
-
-
58149471219
-
Characterization of Tsh receptor antibody induced signaling cascades
-
Morshed SA, Latif R, Davies TF 2009 Characterization of Tsh receptor antibody induced signaling cascades. Endocrinology 150:519-529
-
(2009)
Endocrinology
, vol.150
, pp. 519-529
-
-
Morshed, S.A.1
Latif, R.2
Davies, T.F.3
-
31
-
-
36348946976
-
Functional selectivity through protean and biased agonism: Who steers the ship?
-
Kenakin T 2007 Functional selectivity through protean and biased agonism: who steers the ship? Mol Pharmacol 72:1393-1401
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1393-1401
-
-
Kenakin, T.1
-
32
-
-
34447649922
-
β-Arrestin-biased ligands at seven-transmembrane receptors
-
Violin JD, Lefkowitz RJ 2007 β-Arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 28:416-422
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 416-422
-
-
Violin, J.D.1
Lefkowitz, R.J.2
-
33
-
-
0027312248
-
Topography of equine chorionic gonadotropin epitopes relative to the luteinizing hormone and follicle-stimulating hormone receptor interaction sites
-
Chopineau M, Maurel MC, Combarnous Y, Durand P 1993 Topography of equine chorionic gonadotropin epitopes relative to the luteinizing hormone and follicle-stimulating hormone receptor interaction sites. Mol Cell Endocrinol 92:229-239
-
(1993)
Mol Cell Endocrinol
, vol.92
, pp. 229-239
-
-
Chopineau, M.1
Maurel, M.C.2
Combarnous, Y.3
Durand, P.4
-
34
-
-
24944486315
-
Adenosine 5′-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells
-
Tosca L, Froment P, Solnais P, Ferré P, Foufelle F, Dupont J 2005 Adenosine 5′-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells. Endocrinology 146:4500-4513
-
(2005)
Endocrinology
, vol.146
, pp. 4500-4513
-
-
Tosca, L.1
Froment, P.2
Solnais, P.3
Ferré, P.4
Foufelle, F.5
Dupont, J.6
-
35
-
-
9344220483
-
Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments
-
DiPilato LM, Cheng X, Zhang J 2004 Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments. Proc Natl Acad Sci USA 101:16513-16518
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16513-16518
-
-
DiPilato, L.M.1
Cheng, X.2
Zhang, J.3
-
36
-
-
0035910074
-
Genetically encoded reporters of protein kinase a activity reveal impact of substrate tethering
-
Zhang J, Ma Y, Taylor SS, Tsien RY 2001 Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proc Natl Acad Sci USA 98:14997-15002
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14997-15002
-
-
Zhang, J.1
Ma, Y.2
Taylor, S.S.3
Tsien, R.Y.4
-
37
-
-
0037452623
-
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
-
Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ 2003 Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference. Proc Natl Acad Sci USA 100:1740-1744
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1740-1744
-
-
Ahn, S.1
Nelson, C.D.2
Garrison, T.R.3
Miller, W.E.4
Lefkowitz, R.J.5
-
38
-
-
13444270337
-
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
-
DOI 10.1073/pnas.0409534102
-
Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ 2005 Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor. Proc Natl Acad Sci USA 102:1448-1453 (Pubitemid 40209190)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1448-1453
-
-
Ren, X.-R.1
Reiter, E.2
Ahn, S.3
Kim, J.4
Chen, W.5
Lefkowitz, R.J.6
-
39
-
-
13444291851
-
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
-
DOI 10.1073/pnas.0409532102
-
Kim J, Ahn S, Ren XR, Whalen EJ, Reiter E, Wei H, Lefkowitz RJ 2005 Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling. Proc Natl Acad Sci USA 102:1442-1447 (Pubitemid 40209189)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1442-1447
-
-
Kim, J.1
Ahn, S.2
Ren, X.-R.3
Whalen, E.J.4
Reiter, E.5
Wei, H.6
Lefkowitz, R.J.7
-
40
-
-
0035797505
-
The ERK-dependent signaling is stage-specifically modulated by FSH, during primary Sertoli cell maturation
-
Crépieux P, Marion S, Martinat N, Fafeur V, Vern YL, Kerboeuf D, Guillou F, Reiter E 2001 The ERK-dependent signaling is stage-specifically modulated by FSH, during primary Sertoli cell maturation. Oncogene 20:4696-4709
-
(2001)
Oncogene
, vol.20
, pp. 4696-4709
-
-
Crépieux, P.1
Marion, S.2
Martinat, N.3
Fafeur, V.4
Vern, Y.L.5
Kerboeuf, D.6
Guillou, F.7
Reiter, E.8
-
41
-
-
0036168853
-
Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific
-
Dewi DA, Abayasekara DR, Wheeler-Jones CP 2002 Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific. Endocrinology 143:877-888
-
(2002)
Endocrinology
, vol.143
, pp. 877-888
-
-
Dewi, D.A.1
Abayasekara, D.R.2
Wheeler-Jones, C.P.3
-
42
-
-
23044461829
-
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors
-
Barthet G, Gaven F, Framery B, Shinjo K, Nakamura T, Claeysen S, Bockaert J, Dumuis A 2005 Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. J Biol Chem 280:27924-27934
-
(2005)
J Biol Chem
, vol.280
, pp. 27924-27934
-
-
Barthet, G.1
Gaven, F.2
Framery, B.3
Shinjo, K.4
Nakamura, T.5
Claeysen, S.6
Bockaert, J.7
Dumuis, A.8
-
43
-
-
0035083109
-
Inverse, protean, and ligand-selective agonism: Matters of receptor conformation
-
Kenakin T 2001 Inverse, protean, and ligand-selective agonism: matters of receptor conformation. FASEB J 15:598-611
-
(2001)
FASEB J
, vol.15
, pp. 598-611
-
-
Kenakin, T.1
-
44
-
-
51649084026
-
Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics
-
Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu JM, Gainetdinov RR, Caron MG 2008 Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci USA 105:13656-13661
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13656-13661
-
-
Masri, B.1
Salahpour, A.2
Didriksen, M.3
Ghisi, V.4
Beaulieu, J.M.5
Gainetdinov, R.R.6
Caron, M.G.7
-
45
-
-
36749094552
-
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
-
Wisler JW, DeWire SM, Whalen EJ, Violin JD, Drake MT, Ahn S, Shenoy SK, Lefkowitz RJ 2007 A unique mechanism of β-blocker action: carvedilol stimulates β-arrestin signaling. Proc Natl Acad Sci USA 104:16657-16662
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16657-16662
-
-
Wisler, J.W.1
DeWire, S.M.2
Whalen, E.J.3
Violin, J.D.4
Drake, M.T.5
Ahn, S.6
Shenoy, S.K.7
Lefkowitz, R.J.8
-
46
-
-
34247476171
-
Missing links: Mechanisms of protean agonism
-
Neubig RR 2007 Missing links: mechanisms of protean agonism. Mol Pharmacol 71:1200-1202
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1200-1202
-
-
Neubig, R.R.1
-
47
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB 2007 Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 320:1-13
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 1-13
-
-
Urban, J.D.1
Clarke, W.P.2
Von Zastrow, M.3
Nichols, D.E.4
Kobilka, B.5
Weinstein, H.6
Javitch, J.A.7
Roth, B.L.8
Christopoulos, A.9
Sexton, P.M.10
Miller, K.J.11
Spedding, M.12
Mailman, R.B.13
-
48
-
-
13444261019
-
G protein-coupled receptors: A count of 1001 conformations
-
Vauquelin G, Van Liefde I 2005 G protein-coupled receptors: a count of 1001 conformations. Fundam Clin Pharmacol 19:45-56
-
(2005)
Fundam Clin Pharmacol
, vol.19
, pp. 45-56
-
-
Vauquelin, G.1
Van Liefde, I.2
-
49
-
-
0029054965
-
Agonist-receptor efficacy. II. Agonist trafficking of receptor signals
-
Kenakin T 1995 Agonist-receptor efficacy. II. Agonist trafficking of receptor signals. Trends Pharmacol Sci 16:232-238
-
(1995)
Trends Pharmacol Sci
, vol.16
, pp. 232-238
-
-
Kenakin, T.1
-
50
-
-
0030939070
-
Induction of promiscuous G protein coupling of the follicle-stimulating hormone (FSH) receptor: A novel mechanism for transducing pleiotropic actions of FSH isoforms
-
Arey BJ, Stevis PE, Deecher DC, Shen ES, Frail DE, Negro-Vilar A, Lopez FJ 1997 Induction of promiscuous G protein coupling of the follicle-stimulating hormone (FSH) receptor: a novel mechanism for transducing pleiotropic actions of FSH isoforms. Mol Endocrinol 11:517-526
-
(1997)
Mol Endocrinol
, vol.11
, pp. 517-526
-
-
Arey, B.J.1
Stevis, P.E.2
Deecher, D.C.3
Shen, E.S.4
Frail, D.E.5
Negro-Vilar, A.6
Lopez, F.J.7
-
51
-
-
39749166839
-
Differing pharmacological activities of thiazolidinone analogs at the FSH receptor
-
Arey BJ, Yanofsky SD, Claudia Pérez M, Holmes CP, Wrobel J, Gopalsamy A, Stevis PE, López FJ, Winneker RC 2008 Differing pharmacological activities of thiazolidinone analogs at the FSH receptor. Biochem Biophys Res Commun 368:723-728
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 723-728
-
-
Arey, B.J.1
Yanofsky, S.D.2
Claudia Pérez, M.3
Holmes, C.P.4
Wrobel, J.5
Gopalsamy, A.6
Stevis, P.E.7
López, F.J.8
Winneker, R.C.9
-
52
-
-
33846156211
-
Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH
-
Sanders J, Bolton J, Sanders P, Jeffreys J, Nakatake N, Richards T, Evans M, Kiddie A, Summerhayes S, Roberts E, Miguel RN, Furmaniak J, Smith BR 2006 Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH. Thyroid 16:1195-1206
-
(2006)
Thyroid
, vol.16
, pp. 1195-1206
-
-
Sanders, J.1
Bolton, J.2
Sanders, P.3
Jeffreys, J.4
Nakatake, N.5
Richards, T.6
Evans, M.7
Kiddie, A.8
Summerhayes, S.9
Roberts, E.10
Miguel, R.N.11
Furmaniak, J.12
Smith, B.R.13
-
53
-
-
33751162165
-
Distinct signaling profiles of β1 and β2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy
-
Galandrin S, Bouvier M 2006 Distinct signaling profiles of β1 and β2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Mol Pharmacol 70:1575-1584
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1575-1584
-
-
Galandrin, S.1
Bouvier, M.2
-
54
-
-
34447642715
-
The evasive nature of drug efficacy: Implications for drug discovery
-
Galandrin S, Oligny-Longpré G, Bouvier M 2007 The evasive nature of drug efficacy: implications for drug discovery. Trends Pharmacol Sci 28:423-430
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 423-430
-
-
Galandrin, S.1
Oligny-Longpré, G.2
Bouvier, M.3
-
55
-
-
18544411827
-
μ-Opioid receptor internalization: Opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain
-
Keith DE, Anton B, Murray SR, Zaki PA, Chu PC, Lissin DV, Monteillet-Agius G, Stewart PL, Evans CJ, von Zastrow M 1998 μ-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain. Mol Pharmacol 53:377-384
-
(1998)
Mol Pharmacol
, vol.53
, pp. 377-384
-
-
Keith, D.E.1
Anton, B.2
Murray, S.R.3
Zaki, P.A.4
Chu, P.C.5
Lissin, D.V.6
Monteillet-Agius, G.7
Stewart, P.L.8
Evans, C.J.9
Von Zastrow, M.10
-
56
-
-
0031729845
-
The endothelin subtype a receptor undergoes agonist- And antagonist-mediated internalization in the absence of signaling
-
Bhowmick N, Narayan P, Puett D 1998 The endothelin subtype A receptor undergoes agonist- and antagonist-mediated internalization in the absence of signaling. Endocrinology 139:3185-3192
-
(1998)
Endocrinology
, vol.139
, pp. 3185-3192
-
-
Bhowmick, N.1
Narayan, P.2
Puett, D.3
|