How vital is sleep in Huntington's disease?

Journal of Neurology

Volumn 257, Issue 6, 2010, Pages 882-897

  Goodman, Anna O G ^a   Barker, Roger A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Actigraphy; Circadian rhythms; Huntington's disease; Polysomnography; Quality of life; Sleep

Indexed keywords

PRAMIPEXOLE; ROPINIROLE;

AGING; CHOREA; CHROMOSOME 4; CIRCADIAN RHYTHM; COGNITIVE DEFECT; DEGENERATIVE DISEASE; GENE; HUMAN; HUNTINGTON CHOREA; MENTAL DISEASE; METABOLISM; MOTOR DYSFUNCTION; NERVE TRACT; NEUROPHYSIOLOGY; NONHUMAN; PARASOMNIA; PARKINSON DISEASE; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; REVIEW; SLEEP; SLEEP DISORDER; SURVIVAL TIME; WAKEFULNESS; ANIMAL; BIOLOGICAL MODEL; BRAIN; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN; HUMANS; HUNTINGTON DISEASE; MODELS, NEUROLOGICAL; SLEEP;

EID: 77954424684     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-010-5517-4     Document Type: Review

References (179)

1. MN Alam D McGinty T Bashir S Kumar L Imeri MR Opp R Szymusiak 2004 Interleukin-1beta modulates state-dependent discharge activity of preoptic area and basal forebrain neurons: role in sleep regulation Eur J Neurosci 20 207 216 15245493 (Pubitemid 38932141)
2. MC Antle R Silver 2005 Orchestrating time: arrangements of the brain circadian clock Trends Neurosci 28 145 151 1:CAS:528:DC%2BD2MXitVeis78%3D 15749168 (Pubitemid 40320760)
3. I Arnulf J Nielsen E Lohmann J Schieffer E Wild P Jennum E Konofal M Walker D Oudiette S Tabrizi A Durr 2008 Rapid eye movement sleep disturbances in Huntington disease Arch Neurol 65 482 488 18413470 (Pubitemid 351549956)
4. E Aserinsky 1996 The discovery of REM sleep J Hist Neurosci 5 213 227 1:STN:280:DC%2BD3MrosF2ntA%3D%3D 11618742
5. Aziz A, Fronczek R, Maat-Schieman M, Unmehopa U, Roelandse F, Overeem S, van DS, Lammers GJ, Swaab D, Roos R (2008) Hypocretin and melanin-concentrating hormone in patients with Huntington disease. Brain Pathol 18:474-483
6. NA Aziz JM van der Burg GB Landwehrmeyer P Brundin T Stijnen EHDI Study Group RA Roos 2008 Weight loss in Huntington disease increases with higher CAG repeat number Neurology 71 1506 1513 1:CAS:528:DC%2BD1cXht1yqsrnF 18981372
7. R Basheer RE Strecker MM Thakkar RW McCarley 2004 Adenosine and sleep-wake regulation Prog Neurobiol 73 379 396 1:CAS:528:DC%2BD2cXmslamtbw%3D 15313333 (Pubitemid 39094087)
8. D Bell-Pedersen VM Cassone DJ Earnest SS Golden PE Hardin TL Thomas MJ Zoran 2005 Circadian rhythms from multiple oscillators: lessons from diverse organisms Nat Rev Genet 6 544 556 1:CAS:528:DC%2BD2MXlslWgurs%3D 15951747 (Pubitemid 40910431)
9. RJ Berger 1975 Bioenergetic functions of sleep and activity rhythms and their possible relevance to aging Fed Proc 34 97 102 1:STN:280: DyaE2M%2FlvValug%3D%3D 162800
10. BM Bergmann CA Everson CA Kushida VS Fang CA Leitch DA Schoeller S Refetoff A Rechtschaffen 1989 Sleep deprivation in the rat: V. Energy use and mediation Sleep 12 31 41 1:STN:280:DyaL1M7os1ejsg%3D%3D 2538910 (Pubitemid 19051109)
11. DM Berson 2007 Phototransduction in ganglion-cell photoreceptors Pflugers Arch 454 849 855 1:CAS:528:DC%2BD2sXmvVKnu7s%3D 17351786
12. B Bodosi J Gardi I Hajdu E Szentirmai F Obal Jr JM Krueger 2004 Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation Am J Physiol Regul Integr Comp Physiol 287 R1071 R1079 1:CAS:528:DC%2BD2cXhtVaqt7zF 15475503 (Pubitemid 39391051)
13. BF Boeve MH Silber TJ Ferman 2004 REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies J Geriatr Psychiatry Neurol 17 146 157 15312278 (Pubitemid 39128224)
14. EL Bollen JC Den Heijer C Ponsioen C Kramer EA Van der Velde JG van Dijk RA Roos HA Kamphuisen OJ Buruma 1988 Respiration during sleep in Huntington's chorea J Neurol Sci 84 63 68 1:STN:280:DyaL1c3hsVeqtg%3D%3D 2966850 (Pubitemid 18056745)
15. J Born U Wagner 2004 Awareness in memory: being explicit about the role of sleep Trends Cogn Sci 8 242 244 15165544 (Pubitemid 38692511)
16. H Brunner TC Wetter B Hogl A Yassouridis C Trenkwalder E Friess 2002 Microstructure of the non-rapid eye movement sleep electroencephalogram in patients with newly diagnosed Parkinson's disease: effects of dopaminergic treatment Mov Disord 17 928 933 12360541 (Pubitemid 36040997)
17. MA Carskadon 2004 Sleep deprivation: health consequences and societal impact Med Clin North Am 88 767 776 15087215 x (Pubitemid 38490391)
18. B Cheng MP Mattson 1994 NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults Brain Res 640 56 67 1:CAS:528:DyaK2cXitlKqt7s%3D 7911729 (Pubitemid 24086531)
19. S Chokroverty 1996 Sleep and degenerative neurologic disorders Neurol Clin 14 807 826 1:STN:280:DyaK2s%2Fot1amsQ%3D%3D 8923496 (Pubitemid 26357674)
20. TC Chou TE Scammell JJ Gooley SE Gaus CB Saper J Lu 2003 Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms J Neurosci 23 10691 10702 1:CAS:528:DC%2BD3sXpsFGju78%3D 14627654 (Pubitemid 37485283)
21. L Churchill DM Rector K Yasuda C Fix MJ Rojas T Yasuda JM Krueger 2008 Tumor necrosis factor alpha: activity dependent expression and promotion of cortical column sleep in rats Neuroscience 156 71 80 1:CAS:528: DC%2BD1cXhtFaisLjI 18694809
22. CL Comella TM Nardine NJ Diederich GT Stebbins 1998 Sleep-related violence, injury, and REM sleep behavior disorder in Parkinson's disease Neurology 51 526 529 1:STN:280:DyaK1czntlyjsQ%3D%3D 9710029 (Pubitemid 28406332)
23. M Corsi-Cabrera J Grinberg-Zylberbaum LS Arditti 1975 Caudate nucleus lesion selectively increases paradoxical sleep episodes in the rat Physiol Behav 14 7 11 1:STN:280:DyaE2M3hvVWjuw%3D%3D 168600
24. D Craufurd JC Thompson JS Snowden 2001 Behavioral changes in Huntington Disease Neuropsychiatry Neuropsychol Behav Neurol 14 219 226 1:STN:280:DC%2BD3MnnvV2msg%3D%3D 11725215 (Pubitemid 33051498)
25. KL Davis BM Davis BS Greenwald RC Mohs AA Mathe CA Johns TB Horvath 1986 Cortisol and Alzheimer's disease, I: basal studies Am J Psychiatry 143 300 305 1:STN:280:DyaL287ls1ehsQ%3D%3D 3953862 (Pubitemid 16034087)
26. SM de la Monte JP Vonsattel EP Richardson Jr 1988 Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease J Neuropathol Exp Neurol 47 516 525
27. L de Lecea TS Kilduff C Peyron X Gao PE Foye PE Danielson C Fukuhara EL Battenberg VT Gautvik FS Bartlett WN Frankel AN van den Pol FE Bloom KM Gautvik JG Sutcliffe 1998 The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity Proc Natl Acad Sci USA 95 322 327 9419374 (Pubitemid 28103952)
28. SG De P Gareri VA Sinopoli E David D Rotiroti 1997 Comparative, behavioural and electrocortical effects of tumor necrosis factor-alpha and interleukin-1 microinjected into the locus coeruleus of rat Life Sci 60 555 564 (Pubitemid 27099803)
29. WC Dement LE Miles MA Carskadon 1982 'White paper' on sleep and aging J Am Geriatr Soc 30 25 50 1:STN:280:DyaL387itV2htw%3D%3D 7035529
30. S Deurveilher K Semba 2005 Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state Neuroscience 130 165 183 1:CAS:528:DC%2BD2cXhtVSlurvM 15561433 (Pubitemid 39550423)
31. L Djousse B Knowlton LA Cupples K Marder I Shoulson RH Myers 2002 Weight loss in early stage of Huntington's disease Neurology 59 1325 1330 1:STN:280:DC%2BD38nmslKmsw%3D%3D 12427878 (Pubitemid 35285981)
32. R Dom M Malfroid F Baro 1976 Neuropathology of Huntington's chorea. Studies of the ventrobasal complex of the thalamus Neurology 26 64 68 1:STN:280:DyaE287gtFWiug%3D%3D 128708
33. W Duan Z Guo MP Mattson 2001 Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice J Neurochem 76 619 626 1:CAS:528:DC%2BD3MXhtVGktbo%3D 11208925 (Pubitemid 32097038)
34. K Duff JS Paulsen LJ Beglinger DR Langbehn JC Stout 2007 Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study Biol Psychiatry 62 1341 1346 17481592 (Pubitemid 350180721)
35. JM Ellenbogen 2005 Cognitive benefits of sleep and their loss due to sleep deprivation Neurology 64 E25 E27 15824327
36. W Emser M Brenner T Stober K Schimrigk 1988 Changes in nocturnal sleep in Huntington's and Parkinson's disease J Neurol 235 177 179 1:STN:280: DyaL1c3hsVChsg%3D%3D 2966851
37. S Evers F Stogbauer 2003 Genetic association of Huntington's disease and restless legs syndrome? A family report Mov Disord 18 225 227 12539222 (Pubitemid 36305472)
38. CA Everson 1995 Functional consequences of sustained sleep deprivation in the rat Behav Brain Res 69 43 54 1:STN:280:DyaK28%2FlslOqug%3D%3D 7546317
39. J Fahrenkrug N Popovic B Georg P Brundin J Hannibal 2007 Decreased VIP and VPAC2 receptor expression in the biological clock of the R6/2 Huntington's disease mouse J Mol Neurosci 31 139 148 1:CAS:528:DC%2BD2sXls1Gqtbg%3D 17478887 (Pubitemid 46742297)
40. U Faraguna VV Vyazovskiy AB Nelson G Tononi C Cirelli 2008 A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep J Neurosci 28 4088 4095 1:CAS:528:DC%2BD1cXkvV2ht70%3D 18400908
41. LA Farrer 1985 Diabetes mellitus in Huntington disease Clin Genet 27 62 67 1:STN:280:DyaL2M7lt1Gktg%3D%3D 3156696
42. LA Farrer FJ Meaney 1985 An anthropometric assessment of Huntington's disease patients and families Am J Phys Anthropol 67 185 194 1:STN:280:DyaL28%2FkvVSrsw%3D%3D 2932916 (Pubitemid 15027364)
43. LA Farrer PL Yu 1985 Anthropometric discrimination among affected, at-risk, and not-at-risk individuals in families with Huntington disease Am J Med Genet 21 307 316 1:STN:280:DyaL2M3kvVKitA%3D%3D 3160237
44. M Fava 2004 Daytime sleepiness and insomnia as correlates of depression J Clin Psychiatry 65 Suppl 16 27 32 15575802
45. E Ferrari G Nappi A Vailati E Martignoni PA Bossolo A Polleri 1979 Circadian periodicity of plasma prolactin in some neurological diseases Int J Chronobiol 6 231 242 1:CAS:528:DyaL3cXht1Kmtrk%3D 162341 (Pubitemid 10154358)
46. I Ferrer E Goutan C Marin MJ Rey T Ribalta 2000 Brain-derived neurotrophic factor in Huntington disease Brain Res 866 257 261 1:CAS:528:DC%2BD3cXjsVGisLg%3D 10825501 (Pubitemid 30313028)
47. DR Fish D Sawyers PJ Allen JD Blackie AJ Lees CD Marsden 1991 The effect of sleep on the dyskinetic movements of Parkinson's disease, Gilles de la Tourette syndrome, Huntington's disease, and torsion dystonia Arch Neurol 48 210 214 1:STN:280:DyaK3M7ivVajtQ%3D%3D 1825167
48. RG Foster K Wulff 2005 The rhythm of rest and excess Nat Rev Neurosci 6 407 414 1:CAS:528:DC%2BD2MXjs1Oksrk%3D 15861183 (Pubitemid 40593486)
49. S Frucht JD Rogers PE Greene MF Gordon S Fahn 1999 Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole Neurology 52 1908 1910 1:STN:280:DyaK1M3psl2mtA%3D%3D 10371546 (Pubitemid 29260911)
50. AM Gaba K Zhang K Marder CB Moskowitz P Werner CN Boozer 2005 Energy balance in early-stage Huntington disease Am J Clin Nutr 81 1335 1341 1:CAS:528:DC%2BD2MXlsVWitbk%3D 15941884 (Pubitemid 41710235)
51. JF Gagnon MA Bedard ML Fantini D Petit M Panisset S Rompre J Carrier J Montplaisir 2002 REM sleep behavior disorder and REM sleep without atonia in Parkinson's disease Neurology 59 585 589 1:STN:280:DC%2BD38vjvFSltA%3D%3D 12196654 (Pubitemid 34919994)
52. T Gallopin P Fort E Eggermann B Cauli PH Luppi J Rossier E Audinat M Muhlethaler M Serafin 2000 Identification of sleep-promoting neurons in vitro Nature 404 992 995 1:CAS:528:DC%2BD3cXjtFynsbc%3D 10801127 (Pubitemid 30243592)
53. SE Gaus L Lin E Mignot 2005 CSF hypocretin levels are normal in Huntington's disease patients Sleep 28 1607 1608 16408421 (Pubitemid 41747089)
54. MF Ghilardi G Silvestri A Feigin P Mattis D Zgaljardic C Moisello D Crupi L Marinelli A Dirocco D Eidelberg 2008 Implicit and explicit aspects of sequence learning in pre-symptomatic Huntington's disease Parkinsonism Relat Disord 14 457 464 1:STN:280:DC%2BD1crivVCisA%3D%3D 18316233
55. AO Goodman PR Murgatroyd G Medina-Gomez NI Wood N Finer AJ Vidal-Puig AJ Morton RA Barker 2008 The metabolic profile of early Huntington's disease-a combined human and transgenic mouse study Exp Neurol 210 691 698 1:CAS:528:DC%2BD1cXksVKrsLk%3D 18284928
56. I Grofova M Zhou 1998 Nigral innervation of cholinergic and glutamatergic cells in the rat mesopontine tegmentum: light and electron microscopic anterograde tracing and immunohistochemical studies J Comp Neurol 395 359 379 1:STN:280:DyaK1c3lsF2lug%3D%3D 9596529 (Pubitemid 28287367)
57. V Hahn-Barma B Deweer A Durr C Dode J Feingold B Pillon Y Agid A Brice B Dubois 1998 Are cognitive changes the first symptoms of Huntington's disease? A study of gene carriers J Neurol Neurosurg Psychiatry 64 172 177 1:STN:280:DyaK1c7kvFWksg%3D%3D 9489526 (Pubitemid 28159797)
58. JM Hamilton DP Salmon J Corey-Bloom A Gamst JS Paulsen S Jerkins MW Jacobson G Peavy 2003 Behavioural abnormalities contribute to functional decline in Huntington's disease J Neurol Neurosurg Psychiatry 74 120 122 1:STN:280:DC%2BD3s%2FhsVeltg%3D%3D 12486282 (Pubitemid 36069050)
59. JM Hamilton T Wolfson GM Peavy MW Jacobson J Corey-Bloom 2004 Rate and correlates of weight change in Huntington's disease J Neurol Neurosurg Psychiatry 75 209 212 1:STN:280:DC%2BD2c%2FktF2quw%3D%3D 14742590 (Pubitemid 38183525)
60. MW Hankins SN Peirson RG Foster 2008 Melanopsin: an exciting photopigment Trends Neurosci 31 27 36 1:CAS:528:DC%2BD1cXosFKitg%3D%3D 18054803
61. P Hansotia R Wall J Berendes 1985 Sleep disturbances and severity of Huntington's disease Neurology 35 1672 1674 1:STN:280:DyaL28%2FktVyntQ%3D%3D 2932657 (Pubitemid 16248688)
62. S Happe 2003 Excessive daytime sleepiness and sleep disturbances in patients with neurological diseases: epidemiology and management Drugs 63 2725 2737 14664652 (Pubitemid 38049990)
63. S Happe K Berger 2001 The association of dopamine agonists with daytime sleepiness, sleep problems and quality of life in patients with Parkinson's disease-a prospective study J Neurol 248 1062 1067 1:CAS:528: DC%2BD38XhsFKru70%3D 12013583 (Pubitemid 34134542)
64. PS Harper 1992 The epidemiology of Huntington's disease Hum Genet 89 365 376 1:STN:280:DyaK38zhs1GjsQ%3D%3D 1535611
65. MH Hastings AB Reddy ES Maywood 2003 A clockwork web: circadian timing in brain and periphery, in health and disease Nat Rev Neurosci 4 649 661 1:CAS:528:DC%2BD3sXlvV2itbw%3D 12894240
66. Y Hayashi 1979 The all-night polygraphies for healthy aged persons (1st report)-with special reference to sleep characteristics of the aged persons (author's transl) Rinsho Shinkeigaku 19 653 660 1:STN:280:DyaL3c7nslOgsg%3D%3D 544116
67. I Hindmarch J Dawson N Stanley 2005 A double-blind study in healthy volunteers to assess the effects on sleep of pregabalin compared with alprazolam and placebo Sleep 28 187 193 16171242 (Pubitemid 40362644)
68. AK Ho AO Robbins RA Barker 2006 Huntington's disease patients have selective problems with insight Mov Disord 21 385 389 16211608
69. E Hockly PM Cordery B Woodman A Mahal A van Dellen C Blakemore CM Lewis AJ Hannan GP Bates 2002 Environmental enrichment slows disease progression in R6/2 Huntington's disease mice Ann Neurol 51 235 242 11835380 (Pubitemid 34111446)
70. KF Hoth JS Paulsen DJ Moser D Tranel LA Clark A Bechara 2007 Patients with Huntington's disease have impaired awareness of cognitive, emotional, and functional abilities J Clin Exp Neuropsychol 29 365 376 17497560 (Pubitemid 46763628)
71. Hurelbrink CB, Lewis SJ, Barker RA (2005) The use of the Actiwatch-Neurologica system to objectively assess the involuntary movements and sleep-wake activity in patients with mild-moderate Huntington's disease. J Neurol 252:642-647
72. R Jech J Klempir J Vymazal J Zidovska O Klempirova E Ruzicka J Roth 2007 Variation of selective gray and white matter atrophy in Huntington's disease Mov Disord 22 1783 1789 17579363 (Pubitemid 47597603)
73. TL Jernigan DP Salmon N Butters JR Hesselink 1991 Cerebral structure on MRI, Part II: specific changes in Alzheimer's and Huntington's diseases Biol Psychiatry 29 68 81 1:STN:280:DyaK3M7lvFKjsg%3D%3D 1825793
74. ME Jewett DJ Dijk RE Kronauer DF Dinges 1999 Dose-response relationship between sleep duration and human psychomotor vigilance and subjective alertness Sleep 22 171 179 1:STN:280:DyaK1M3hslWiug%3D%3D 10201061
75. CL Julien JC Thompson S Wild P Yardumian JS Snowden G Turner D Craufurd 2007 Psychiatric disorders in preclinical Huntington's disease J Neurol Neurosurg Psychiatry 78 939 943 17178819 (Pubitemid 47310828)
76. J Kassubek FD Juengling T Kioschies K Henkel J Karitzky B Kramer D Ecker J Andrich C Saft P Kraus AJ Aschoff AC Ludolph GB Landwehrmeyer 2004 Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study J Neurol Neurosurg Psychiatry 75 213 220 1:STN:280: DC%2BD2c%2Fkt1Sjsg%3D%3D 14742591 (Pubitemid 38183526)
77. T Kodama Y Honda 1999 Acetylcholine and glutamate release during sleep-wakefulness in the pedunculopontine tegmental nucleus and norepinephrine changes regulated by nitric oxide Psychiatry Clin Neurosci 53 109 111 1:CAS:528:DyaK1MXktlynu7c%3D 10459664 (Pubitemid 29299886)
78. WP Koella 1984 The organization and regulation of sleep. A review of the experimental evidence and a novel integrated model of the organizing and regulating apparatus Experientia 40 309 338 1:CAS:528:DyaL2cXitVKqsr8%3D 6370714
79. B Kremer B Weber MR Hayden 1992 New insights into the clinical features, pathogenesis and molecular genetics of Huntington disease Brain Pathol 2 321 335 1:STN:280:DyaK2c%2Fptlyhuw%3D%3D 1341966
80. HP Kremer RA Roos 1992 Weight loss in Huntington's disease Arch Neurol 49 349 1:STN:280:DyaK383hsFWqtw%3D%3D 1532711
81. HP Kremer RA Roos G Dingjan E Marani GT Bots 1990 Atrophy of the hypothalamic lateral tuberal nucleus in Huntington's disease J Neuropathol Exp Neurol 49 371 382 1:STN:280:DyaK3czgtVejsQ%3D%3D 2141871 (Pubitemid 20207798)
82. JM Krueger F Obal 1993 A neuronal group theory of sleep function J Sleep Res 2 63 69 10607073
83. JM Krueger F Obal Jr 2003 Sleep function Front Biosci 8 d511 d519 1:CAS:528:DC%2BD3sXjvVWltrs%3D 12700033
84. JM Krueger DM Rector S Roy HP Van Dongen G Belenky J Panksepp 2008 Sleep as a fundamental property of neuronal assemblies Nat Rev Neurosci 9 910 919 1:CAS:528:DC%2BD1cXhtl2gsbzF 18985047
85. KA Kubitz DM Landers SJ Petruzzello M Han 1996 The effects of acute and chronic exercise on sleep. A meta-analytic review Sports Med 21 277 291 1:STN:280:DyaK283psVyltg%3D%3D 8726346 (Pubitemid 126425985)
86. S Kumar M Bhatia M Behari 2002 Sleep disorders in Parkinson's disease Mov Disord 17 775 781 12210875 (Pubitemid 41295024)
87. CA Kushida BM Bergmann A Rechtschaffen 1989 Sleep deprivation in the rat: IV. Paradoxical sleep deprivation Sleep 12 22 30 1:STN:280:DyaL1M7os1aquw%3D%3D 2928623 (Pubitemid 19051108)
88. EH Kwok NJ Dun 2002 Orexin/hypocretin system: obesity, narcolepsy and beyond Drug News Perspect 15 166 174 1:CAS:528:DC%2BD38XkvFGmsbY%3D 12677259
89. EW Lamont FO James DB Boivin N Cermakian 2007 From circadian clock gene expression to pathologies Sleep Med 8 547 556 17395534 (Pubitemid 47181205)
90. S Laureys P Peigneux F Perrin P Maquet 2002 Sleep and motor skill learning Neuron 35 5 7 1:CAS:528:DC%2BD38XlslOqsLk%3D 12123601 (Pubitemid 34804315)
91. J Lemiere M Decruyenaere G Evers-Kiebooms E Vandenbussche R Dom 2004 Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation-a longitudinal follow-up study J Neurol 251 935 942 1:CAS:528:DC%2BD2cXosVSrtLY%3D 15316797 (Pubitemid 39119311)
92. R Leproult G Copinschi O Buxton E Van Cauter 1997 Sleep loss results in an elevation of cortisol levels the next evening Sleep 20 865 870 1:STN:280:DyaK1c%2FnslOqtw%3D%3D 9415946 (Pubitemid 27524715)
93. PL Lowrey JS Takahashi 2004 Mammalian circadian biology: elucidating genome-wide levels of temporal organization Annu Rev Genomics Hum Genet 5 407 441 1:CAS:528:DC%2BD2cXosl2isL8%3D 15485355
94. J Lu MA Greco P Shiromani CB Saper 2000 Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep J Neurosci 20 3830 3842 1:CAS:528:DC%2BD3cXjtlKqsbs%3D 10804223 (Pubitemid 30266244)
95. Lynch WJ, Girgenti MJ, Breslin FJ, Newton SS, Taylor JR (2008) Gene profiling the response to repeated cocaine self-administration in dorsal striatum: a focus on circadian genes. Brain Res 1213:166-177
96. A Manfridi D Brambilla S Bianchi M Mariotti MR Opp L Imeri 2003 Interleukin-1beta enhances non-rapid eye movement sleep when microinjected into the dorsal raphe nucleus and inhibits serotonergic neurons in vitro Eur J Neurosci 18 1041 1049 12956704 (Pubitemid 37115026)
97. Mano T, Shiozawa Z, Sobue I (1982) Extrapyramidal involuntary movements during sleep. Electroencephalogr Clin Neurophysiol Suppl 431-442
98. EF Masucci FT Borts JF Kurtzke 1990 CT brainstem abnormalities in the differential diagnosis of Huntington's disease Comput Med Imaging Graph 14 205 212 1:STN:280:DyaK3c3mvVChsg%3D%3D 2140710 (Pubitemid 20185006)
99. D McGinty R Szymusiak 2000 The sleep-wake switch: a neuronal alarm clock Nat Med 6 510 511 1:CAS:528:DC%2BD3cXjtFyhs7o%3D 10802704 (Pubitemid 30305899)
100. J Mena-Segovia L Cintra O Prospero-Garcia M Giordano 2002 Changes in sleep-waking cycle after striatal excitotoxic lesions Behav Brain Res 136 475 481 12429410 (Pubitemid 35333263)
101. MM Mitler MA Carskadon CA Czeisler WC Dement DF Dinges RC Graeber 1988 Catastrophes, sleep, and public policy: consensus report Sleep 11 100 109 1:STN:280:DyaL1c3gsVKrtA%3D%3D 3283909
102. A Montoya BH Price M Menear M Lepage 2006 Brain imaging and cognitive dysfunctions in Huntington's disease J Psychiatry Neurosci 31 21 29 16496032 (Pubitemid 43305307)
103. J Montplaisir D Petit D Lorrain S Gauthier T Nielsen 1995 Sleep in Alzheimer's disease: further considerations on the role of brainstem and forebrain cholinergic populations in sleep-wake mechanisms Sleep 18 145 148 1:STN:280:DyaK2MzjsVKnsA%3D%3D 7610309
104. RY Moore 2007 Suprachiasmatic nucleus in sleep-wake regulation Sleep Med 8 Suppl 3 27 33 18032104
105. LM Morales J Estevez H Suarez R Villalobos d B Chacin E Bonilla 1989 Nutritional evaluation of Huntington disease patients Am J Clin Nutr 50 145 150 1:CAS:528:DyaL1MXltFChtrY%3D 2526577 (Pubitemid 19195534)
106. AJ Morton NI Wood MH Hastings C Hurelbrink RA Barker ES Maywood 2005 Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease J Neurosci 25 157 163 1:CAS:528:DC%2BD2MXhtVWrsr4%3D 15634777 (Pubitemid 40110776)
107. G Moruzzi HW Magoun 1995 Brain stem reticular formation and activation of the EEG. 1949 J Neuropsychiatry Clin Neurosci 7 251 267 1:STN:280: DyaK2MzltlSmtQ%3D%3D 7626974
108. M Muhlau A Weindl AM Wohlschlager C Gaser M Stadtler M Valet C Zimmer J Kassubek A Peinemann 2007 Voxel-based morphometry indicates relative preservation of the limbic prefrontal cortex in early Huntington disease J Neural Transm 114 367 372 1:STN:280:DC%2BD2s7htlKgtQ%3D%3D 17024326 (Pubitemid 46328656)
109. JM Mullington JL Chan HP Van Dongen MP Szuba J Samaras NJ Price HK Meier-Ewert DF Dinges CS Mantzoros 2003 Sleep loss reduces diurnal rhythm amplitude of leptin in healthy men J Neuroendocrinol 15 851 854 1:CAS:528:DC%2BD3sXmvFGms7c%3D 12899679 (Pubitemid 37038610)
110. PJ O'Connor SD Youngstedt 1995 Influence of exercise on human sleep Exerc Sport Sci Rev 23 105 134 7556348
111. F Obal Jr JM Krueger 2003 Biochemical regulation of non-rapid-eye- movement sleep Front Biosci 8 d520 d550 1:CAS:528:DC%2BD3sXjvVWltLg%3D 12700031
112. MM Ohayon MA Carskadon C Guilleminault MV Vitiello 2004 Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan Sleep 27 1255 1273 15586779 (Pubitemid 44138893)
113. WG Ondo VK Dat H Khan F Atassi C Kwak J Jankovic 2001 Daytime sleepiness and other sleep disorders in Parkinson's disease Neurology 57 1392 1396 1:STN:280:DC%2BD3MrmslCnuw%3D%3D 11673578 (Pubitemid 32995718)
114. K Oyanagi S Takeda H Takahashi E Ohama F Ikuta 1989 A quantitative investigation of the substantia nigra in Huntington's disease Ann Neurol 26 13 19 1:STN:280:DyaL1Mznt1OmsQ%3D%3D 2528318 (Pubitemid 19190038)
115. EF Pace-Schott JA Hobson 2002 The neurobiology of sleep: genetics, cellular physiology and subcortical networks Nat Rev Neurosci 3 591 605 1:CAS:528:DC%2BD38XlslGrt7g%3D 12154361
116. PN Pallier ES Maywood Z Zheng JE Chesham AN Inyushkin R Dyball MH Hastings AJ Morton 2007 Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease J Neurosci 27 7869 7878 1:CAS:528: DC%2BD2sXos1Crt7Y%3D 17634381 (Pubitemid 47093825)
117. PN Pallier AJ Morton 2009 Management of sleep/wake cycles improves cognitive function in a transgenic mouse model of Huntington's disease Brain Res 1279 90 98 1:CAS:528:DC%2BD1MXnsFajt7g%3D 19450569
118. SR Patel S Redline 2004 Two epidemics: are we getting fatter as we sleep less? Sleep 27 602 603 15282992 (Pubitemid 38823354)
119. JS Paulsen C Nehl KF Hoth JE Kanz M Benjamin R Conybeare B McDowell B Turner 2005 Depression and stages of Huntington's disease J Neuropsychiatry Clin Neurosci 17 496 502 16387989 (Pubitemid 41790050)
120. JS Paulsen RE Ready JM Hamilton MS Mega JL Cummings 2001 Neuropsychiatric aspects of Huntington's disease J Neurol Neurosurg Psychiatry 71 310 314 1:STN:280:DC%2BD3Mvms12hsQ%3D%3D 11511702
121. P Peigneux S Laureys S Fuchs F Collette F Perrin J Reggers C Phillips C Degueldre FG Del J Aerts A Luxen P Maquet 2004 Are spatial memories strengthened in the human hippocampus during slow wave sleep? Neuron 44 535 545 1:CAS:528:DC%2BD2cXpvVChsLw%3D 15504332 (Pubitemid 39423353)
122. A Petersen J Gil ML Maat-Schieman M Bjorkqvist H Tanila IM Araujo R Smith N Popovic N Wierup P Norlen JY Li RA Roos F Sundler H Mulder P Brundin 2005 Orexin loss in Huntington's disease Hum Mol Genet 14 39 47 1:CAS:528: DC%2BD2MXitFGmsQ%3D%3D 15525658 (Pubitemid 40123461)
123. D Petit JF Gagnon ML Fantini L Ferini-Strambi J Montplaisir 2004 Sleep and quantitative EEG in neurodegenerative disorders J Psychosom Res 56 487 496 15172204 (Pubitemid 38686687)
124. Peyron C, Tighe DK, van den Pol AN, de LL, Heller HC, Sutcliffe JG Kilduff TS (1998) Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 18:9996-10015 (Pubitemid 28543775)
125. HD Piggins A Loudon 2005 Circadian biology: clocks within clocks Curr Biol 15 R455 R457 1:CAS:528:DC%2BD2MXltlajtb8%3D 15964264 (Pubitemid 40841342)
126. G Plazzi R Corsini F Provini G Pierangeli P Martinelli P Montagna E Lugaresi P Cortelli 1997 REM sleep behavior disorders in multiple system atrophy Neurology 48 1094 1097 1:STN:280:DyaK2s3msVSgtw%3D%3D 9109907 (Pubitemid 27175645)
127. W Plihal J Born 1999 Effects of early and late nocturnal sleep on priming and spatial memory Psychophysiology 36 571 582 1:STN:280:DyaK1MzntVKisQ%3D%3D 10442025 (Pubitemid 29357552)
128. S Podolsky NA Leopold DS Sax 1972 Increased frequency of diabetes mellitus in patients with Huntington's chorea Lancet 1 1356 1358 1:STN:280:DyaE383gs1aluw%3D%3D 4113563
129. M Politis N Pavese YF Tai SJ Tabrizi RA Barker P Piccini 2008 Hypothalamic involvement in Huntington's disease: an in vivo PET study Brain 131 2860 2869 18829696
130. V Popovic M Svetel M Djurovic S Petrovic M Doknic S Pekic D Miljic N Milic J Glodic C Dieguez FF Casanueva V Kostic 2004 Circulating and cerebrospinal fluid ghrelin and leptin: potential role in altered body weight in Huntington's disease Eur J Endocrinol 151 451 455 1:CAS:528: DC%2BD2cXpsFChtLg%3D 15476444 (Pubitemid 39430262)
131. Postuma RB, Gagnon JF, Vendette M, Fantini ML, Massicotte-Marquez J, Montplaisir J (2009) Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology 72:1296-1300
132. RE Pratley AD Salbe E Ravussin JN Caviness 2000 Higher sedentary energy expenditure in patients with Huntington's disease Ann Neurol 47 64 70 1:STN:280:DC%2BD3c%2FpsF2lsQ%3D%3D 10632102 (Pubitemid 30033651)
133. PN Prinz PP Vitaliano MV Vitiello J Bokan M Raskind E Peskind C Gerber 1982 Sleep, EEG and mental function changes in senile dementia of the Alzheimer's type Neurobiol Aging 3 361 370 1:STN:280:DyaL3s7pt1OgtA%3D%3D 7170052
134. NM Punjabi E Shahar S Redline DJ Gottlieb R Givelber HE Resnick 2004 Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study Am J Epidemiol 160 521 530 15353412 (Pubitemid 39215628)
135. Z Qin L Zhang F Sun X Fang C Meng C Tanner P Chan 2009 Health related quality of life in early Parkinson's disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort Parkinsonism Relat Disord 15 767 771 19553154
136. RE Ready M Mathews A Leserman JS Paulsen 2008 Patient and caregiver quality of life in Huntington's disease Mov Disord 23 721 726 18175350
137. A Rechtschaffen BM Bergmann CA Everson CA Kushida MA Gilliland 2002 Sleep deprivation in the rat: X. Integration and discussion of the findings. 1989 Sleep 25 68 87 11833857
138. Rechtschaffen A, Kales A (1968) A manual of standardized terminology, technique and scoring system for sleep stages of human sleep. Brain Information Service, Los Angeles
139. AO Robbins AK Ho RA Barker 2006 Weight changes in Huntington's disease Eur J Neurol 13 e7 1:STN:280:DC%2BD28vls1GgtQ%3D%3D 16879284
140. HD Rosas WJ Koroshetz YI Chen C Skeuse M Vangel ME Cudkowicz K Caplan K Marek LJ Seidman N Makris BG Jenkins JM Goldstein 2003 Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis Neurology 60 1615 1620 1:STN:280:DC%2BD3s3kvVWqtA%3D%3D 12771251 (Pubitemid 36618087)
141. HD Rosas DH Salat SY Lee AK Zaleta V Pappu B Fischl D Greve N Hevelone SM Hersch 2008 Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity Brain 131 1057 1068 18337273 (Pubitemid 351499426)
142. A Rosenblatt 2007 Neuropsychiatry of Huntington's disease Dialogues Clin Neurosci 9 191 197 17726917 (Pubitemid 47075466)
143. NF Ruby CE Hwang C Wessells F Fernandez P Zhang R Sapolsky HC Heller 2008 Hippocampal-dependent learning requires a functional circadian system Proc Natl Acad Sci USA 105 15593 15598 1:CAS:528:DC%2BD1cXht1GisLvJ 18832172
144. PR Sanberg HC Fibiger RF Mark 1981 Body weight and dietary factors in Huntington's disease patients compared with matched controls Med J Aust 1 407 409 1:STN:280:DyaL3M3ksVCmsA%3D%3D 6454826
145. CB Saper TC Chou TE Scammell 2001 The sleep switch: hypothalamic control of sleep and wakefulness Trends Neurosci 24 726 731 1:CAS:528: DC%2BD3MXosFKlsrY%3D 11718878
146. CB Saper TE Scammell J Lu 2005 Hypothalamic regulation of sleep and circadian rhythms Nature 437 1257 1263 1:CAS:528:DC%2BD2MXhtFCrurrP 16251950 (Pubitemid 41568665)
147. AH Schapira 2000 Sleep attacks (sleep episodes) with pergolide Lancet 355 1332 1333 1:CAS:528:DC%2BD3cXivVCqsbc%3D 10776749
148. AJ Scheen E Van Cauter 1998 The roles of time of day and sleep quality in modulating glucose regulation: clinical implications Horm Res 49 191 201 1:CAS:528:DyaK1cXitVCltrc%3D 9550124 (Pubitemid 28138337)
149. ES Schernhammer F Laden FE Speizer WC Willett DJ Hunter I Kawachi CS Fuchs GA Colditz 2003 Night-shift work and risk of colorectal cancer in the nurses' health study J Natl Cancer Inst 95 825 828 12783938 (Pubitemid 36798430)
150. DF Scott KW Heathfield B Toone JH Margerison 1972 The EEG in Huntington's chorea: a clinical and neuropathological study J Neurol Neurosurg Psychiatry 35 97 102 1:STN:280:DyaE387osVCitw%3D%3D 4260288
151. S Sephton D Spiegel 2003 Circadian disruption in cancer: a neuroendocrine-immune pathway from stress to disease? Brain Behav Immun 17 321 328 1:CAS:528:DC%2BD3sXmslegsLc%3D 12946654 (Pubitemid 36999839)
152. JE Sherin PJ Shiromani RW McCarley CB Saper 1996 Activation of ventrolateral preoptic neurons during sleep Science 271 216 219 1:CAS:528:DyaK28XktFOktQ%3D%3D 8539624 (Pubitemid 26033304)
153. DL Sherrill K Kotchou SF Quan 1998 Association of physical activity and human sleep disorders Arch Intern Med 158 1894 1898 1:STN:280: DyaK1cvjtVCrtw%3D%3D 9759685 (Pubitemid 28440862)
154. M Shibata 1990 Hypothalamic neuronal responses to cytokines Yale J Biol Med 63 147 156 1:CAS:528:DyaK3cXmt1yqsbg%3D 2205055 (Pubitemid 20342084)
155. R Shiwach 1994 Psychopathology in Huntington's disease patients Acta Psychiatr Scand 90 241 246 1:STN:280:DyaK2M7jtlersA%3D%3D 7831992 (Pubitemid 24303590)
156. JM Siegel 2009 Sleep viewed as a state of adaptive inactivity Nat Rev Neurosci 10 747 753 1:CAS:528:DC%2BD1MXpsVers7o%3D 19654581
157. R Silvestri M Raffaele P De Domenico A Tisano G Mento C Casella MC Tripoli S Serra R Di Perri 1995 Sleep features in Tourette's syndrome, neuroacanthocytosis and Huntington's chorea Neurophysiol Clin 25 66 77 1:STN:280:DyaK2MzislSgsw%3D%3D 7603414
158. SK Sishta A Troupe KS Marszalek LM Kremer 1974 Huntington's chorea: an electroencephalographic and psychometric study Electroencephalogr Clin Neurophysiol 36 387 393 1:STN:280:DyaE2M%2FlslGnug%3D%3D 4140065
159. K Spiegel R Leproult M L'hermite-Baleriaux G Copinschi PD Penev E Van Cauter 2004 Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin J Clin Endocrinol Metab 89 5762 5771 1:CAS:528:DC%2BD2cXhtVSisbnK 15531540 (Pubitemid 39518469)
160. TL Steininger H Gong D McGinty R Szymusiak 2001 Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups J Comp Neurol 429 638 653 1:CAS:528: DC%2BD3MXitlejsw%3D%3D 11135241 (Pubitemid 32011859)
161. M Steriade 2003 The corticothalamic system in sleep Front Biosci 8 d878 d899 1:CAS:528:DC%2BD3sXjvVWqsbo%3D 12700074 (Pubitemid 38943170)
162. N Stoy E McKay 2000 Weight loss in Huntington's disease Ann Neurol 48 130 131 1:STN:280:DC%2BD3czltVOgsw%3D%3D 10894233
163. RE Strecker S Morairty MM Thakkar T Porkka-Heiskanen R Basheer LJ Dauphin DG Rainnie CM Portas RW Greene RW McCarley 2000 Adenosinergic modulation of basal forebrain and preoptic/anterior hypothalamic neuronal activity in the control of behavioral state Behav Brain Res 115 183 204 1:CAS:528: DC%2BD3cXms1Sqtrk%3D 11000420
164. DF Swaab MA Hofman PJ Lucassen JS Purba FC Raadsheer JA Van de Nes 1993 Functional neuroanatomy and neuropathology of the human hypothalamus Anat Embryol (Berl) 187 317 330 1:STN:280:DyaK3s3ovF2ktA%3D%3D
165. N Tachibana Y Oka 2004 Longitudinal change in REM sleep components in a patient with multiple system atrophy associated with REM sleep behavior disorder: paradoxical improvement of nocturnal behaviors in a progressive neurodegenerative disease Sleep Med 5 155 158 15033136 (Pubitemid 38351828)
166. S Taheri L Lin D Austin T Young E Mignot 2004 Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index PLoS Med 1 e62 15602591 (Pubitemid 40418884)
167. JS Takahashi HK Hong CH Ko EL McDearmon 2008 The genetics of mammalian circadian order and disorder: implications for physiology and disease Nat Rev Genet 9 764 775 1:CAS:528:DC%2BD1cXhtFeitrnN 18802415
168. N Taylor D Bramble 1997 Sleep disturbance and Huntingdon's disease Br J Psychiatry 171 393 1:STN:280:DyaK1c%2FktVOksg%3D%3D 9373439
169. AJ Tietzel LC Lack 2002 The recuperative value of brief and ultra-brief naps on alertness and cognitive performance J Sleep Res 11 213 218 12220317
170. FW Turek C Joshu A Kohsaka E Lin G Ivanova E McDearmon A Laposky S Losee-Olson A Easton DR Jensen RH Eckel JS Takahashi J Bass 2005 Obesity and metabolic syndrome in circadian Clock mutant mice Science 308 1043 1045 1:CAS:528:DC%2BD2MXjvF2qsb0%3D 15845877 (Pubitemid 40664419)
171. EJ Van Someren 2000 Circadian and sleep disturbances in the elderly Exp Gerontol 35 1229 1237 11113604
172. Videnovic A, Leurgans S, Fan W, Jaglin J, Shannon KM (2009) Daytime somnolence and nocturnal sleep disturbances in Huntington disease. Parkinsonism Relat Disord 15:471-474
173. J Villablanca 1972 Permanent reduction in sleep after removal of cerebral cortex and striatum in cats Brain Res 36 463 468 1:STN:280: DyaE38%2FpslGrsg%3D%3D 4333235
174. JP Vonsattel RH Myers TJ Stevens RJ Ferrante ED Bird EP Richardson Jr 1985 Neuropathological classification of Huntington's disease J Neuropathol Exp Neurol 44 559 577 1:STN:280:DyaL28%2Fjs1egsg%3D%3D 2932539
175. AG Watts LW Swanson 1987 Efferent projections of the suprachiasmatic nucleus: II. Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat J Comp Neurol 258 230 252 1:STN:280:DyaL2s3itlanug%3D%3D 2438309 (Pubitemid 17050998)
176. TC Wetter V Collado-Seidel T Pollmacher A Yassouridis C Trenkwalder 2000 Sleep and periodic leg movement patterns in drug-free patients with Parkinson's disease and multiple system atrophy Sleep 23 361 367 1:STN:280: DC%2BD3c3mvFGitQ%3D%3D 10811380 (Pubitemid 30263169)
177. M Wiegand AA Moller CJ Lauer S Stolz W Schreiber M Dose JC Krieg 1991 Nocturnal sleep in Huntington's disease J Neurol 238 203 208 1:STN:280:DyaK3MznsVWrsg%3D%3D 1832711
178. SD Youngstedt PJ O'Connor RK Dishman 1997 The effects of acute exercise on sleep: a quantitative synthesis Sleep 20 203 214 1:STN:280: DyaK2szit1alsA%3D%3D 9178916 (Pubitemid 27242270)
179. C Zuccato A Ciammola D Rigamonti BR Leavitt D Goffredo L Conti ME MacDonald RM Friedlander V Silani MR Hayden T Timmusk S Sipione E Cattaneo 2001 Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Science 293 493 498 1:CAS:528:DC%2BD3MXlsFGjtr0%3D 11408619 (Pubitemid 32679077)