-
1
-
-
0030987548
-
Copolymer 1 induces T cells of the T helper type 2 that cross-react with myelin basic protein and suppress experimental autoimmune encephalomyelitis
-
Aharoni R, Teitelbaum D, Sela M, Arnon R. Copolymer 1 induces T cells of the T helper type 2 that cross-react with myelin basic protein and suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 1997; 94: 10821-10826
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10821-10826
-
-
Aharoni, R.1
Teitelbaum, D.2
Sela, M.3
Arnon, R.4
-
2
-
-
70449106029
-
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
-
Bartholomäus I, Kawakami N, Odoardi F, Schlä ger C, Miljkovic D, Ellwart JW, et al. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 2009; 462: 94-98
-
(2009)
Nature
, vol.462
, pp. 94-98
-
-
Bartholomäus, I.1
Kawakami, N.2
Odoardi, F.3
Schläger, C.4
Miljkovic, D.5
Ellwart, J.W.6
-
3
-
-
33745631754
-
Antigen presentation in autoimmunity and CNS inflammation: How T lymphocytes recognize the brain
-
Becher B, Bechmann I, Greter M. Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain. J Mol Med 2006; 84: 532-543
-
(2006)
J Mol Med
, vol.84
, pp. 532-543
-
-
Becher, B.1
Bechmann, I.2
Greter, M.3
-
4
-
-
0035923519
-
+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis
-
+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. Proc Natl Acad Sci USA 2001; 98: 13942-13947
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13942-13947
-
-
Beeton, C.1
Wulff, H.2
Barbaria, J.3
Clot-Faybesse, O.4
Pennington, M.5
Bernard, D.6
-
5
-
-
33751232672
-
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
-
Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, et al. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc Natl Acad Sci USA 2006; 103: 17414-17419
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17414-17419
-
-
Beeton, C.1
Wulff, H.2
Standifer, N.E.3
Azam, P.4
Mullen, K.M.5
Pennington, M.W.6
-
6
-
-
0019465142
-
The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
-
Ben-Nun A, Wekerle H, Cohen IR. The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol 1981; 11: 195-199
-
(1981)
Eur J Immunol
, vol.11
, pp. 195-199
-
-
Ben-Nun, A.1
Wekerle, H.2
Cohen, I.R.3
-
7
-
-
0034618134
-
Nicotinic acid adenine dinucleo-tide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signaling
-
Berg I, Potter BVL, Mayr GW, Guse AH. Nicotinic acid adenine dinucleo-tide phosphate (NAADP(+)) is an essential regulator of T-lymphocyte Ca(2+)-signaling. J Cell Biol 2000; 150: 581-588
-
(2000)
J Cell Biol
, vol.150
, pp. 581-588
-
-
Berg, I.1
Bvl, P.2
Mayr, G.W.3
Guse, A.H.4
-
8
-
-
13944266418
-
Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment
-
Bhakta NR, Oh DY, Lewis RS. Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment. Nat Immunol 2005; 6: 143-151
-
(2005)
Nat Immunol
, vol.6
, pp. 143-151
-
-
Bhakta, N.R.1
Oh, D.Y.2
Lewis, R.S.3
-
9
-
-
68149150032
-
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system
-
Bittner S, Meuth SG, Gö bel K, Melzer N, Herrmann AM, Simon OJ, et al. TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. Brain 2009; 132: 2501-2516
-
(2009)
Brain
, vol.132
, pp. 2501-2516
-
-
Bittner, S.1
Meuth, S.G.2
Göbel, K.3
Melzer, N.4
Herrmann, A.M.5
Simon, O.J.6
-
11
-
-
33646576875
-
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
-
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006; 441: 179-185
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
Gwack, Y.2
Prakriya, M.3
Srikanth, S.4
Puppel, S.H.5
Tanasa, B.6
-
12
-
-
0035005143
-
Migratory activity and functional changes of green fluorescent effector T cells before and during experimental autoimmune encephalomyelitis
-
Flü gel A, Berkowicz T, Ritter T, Labeur M, Jenne D, Li Z, et al. Migratory activity and functional changes of green fluorescent effector T cells before and during experimental autoimmune encephalomyelitis. Immunity 2001; 14: 547-560
-
(2001)
Immunity
, vol.14
, pp. 547-560
-
-
Flügel, A.1
Berkowicz, T.2
Ritter, T.3
Labeur, M.4
Jenne, D.5
Li, Z.6
-
13
-
-
0344780200
-
+ T lymphocytes: Green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain
-
+ T lymphocytes: green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain. Nature Med 1999; 5: 843-847
-
(1999)
Nature Med
, vol.5
, pp. 843-847
-
-
Flügel, A.1
Willem, M.2
Berkowicz, T.3
Wekerle, H.4
-
14
-
-
28744442319
-
Antigen-specific therapies in multiple sclerosis: Going beyond proteins and peptides
-
Fontoura P, Garren H, Steinman L. Antigen-specific therapies in multiple sclerosis: going beyond proteins and peptides. Int Rev Immunol 2005; 24: 415-446
-
(2005)
Int Rev Immunol
, vol.24
, pp. 415-446
-
-
Fontoura, P.1
Garren, H.2
Steinman, L.3
-
15
-
-
33745217366
-
Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay
-
Gasser A, Bruhn S, Guse AH. Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay. J Biol Chem 2006; 281: 16906-16913
-
(2006)
J Biol Chem
, vol.281
, pp. 16906-16913
-
-
Gasser, A.1
Bruhn, S.2
Guse, A.H.3
-
16
-
-
0033522178
-
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose
-
Guse AH, da Silva CP, Berg I, Skapenko AL, Weber K, Heyer P, et al. Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose. Nature 1999; 398: 70-73
-
(1999)
Nature
, vol.398
, pp. 70-73
-
-
Guse, A.H.1
Da Silva, C.P.2
Berg, I.3
Skapenko, A.L.4
Weber, K.5
Heyer, P.6
-
17
-
-
0028811179
-
Non-radioactive, isomer-specific inositol phosphate mass determinations: High-performance liquid chromatography-micro-metal-dye detection strongly improves speed and sensitivity of analyses from cells and micro-enzyme assays
-
Guse AH, Goldwich A, Weber K, Mayr GW. Non-radioactive, isomer-specific inositol phosphate mass determinations: high-performance liquid chromatography-micro-metal-dye detection strongly improves speed and sensitivity of analyses from cells and micro-enzyme assays. J Chromatogr B Biomed Appl 1995; 672: 189-198
-
(1995)
J Chromatogr B Biomed Appl
, vol.672
, pp. 189-198
-
-
Guse, A.H.1
Goldwich, A.2
Weber, K.3
Mayr, G.W.4
-
18
-
-
0024274081
-
Immune mechanisms in inflammatory neuropathy
-
Hartung H-P, Heininger K, Schäfer B, Fierz W, Toyka KV. Immune mechanisms in inflammatory neuropathy. Ann NY Acad Sci 1988; 540: 122-161
-
(1988)
Ann NY Acad Sci
, vol.540
, pp. 122-161
-
-
Hartung, H.-P.1
Heininger, K.2
Schäfer, B.3
Fierz, W.4
Toyka, K.V.5
-
19
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
Kappos L, Antel J, Comi G, Montalban X, O'Connor P, Polman CH, et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med 2006; 355: 1124-1140
-
(2006)
N Engl J Med
, vol.355
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
Montalban, X.4
O'Connor, P.5
-
20
-
-
1642458745
-
The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomye-litis
-
Kawakami N, Lassmann S, Li Z, Odoardi F, Ritter T, Ziemssen T, et al. The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomye-litis. J Exp Med 2004; 199: 185-197
-
(2004)
J Exp Med
, vol.199
, pp. 185-197
-
-
Kawakami, N.1
Lassmann, S.2
Li, Z.3
Odoardi, F.4
Ritter, T.5
Ziemssen, T.6
-
21
-
-
22344453196
-
Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion
-
Kawakami N, Nägerl UV, Odoardi F, Bonhoeffer T, Wekerle H, Flü gel A. Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion. J Exp Med 2005a; 201: 1805-1814
-
(2005)
J Exp Med
, vol.201
, pp. 1805-1814
-
-
Kawakami, N.1
Nägerl, U.V.2
Odoardi, F.3
Bonhoeffer, T.4
Wekerle, H.5
Flügel, A.6
-
23
-
-
65649096159
-
Localizing central nervous system immune surveillance: Menin-geal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis
-
Kivisäkk P, Imitola J, Rasmussen S, Elyaman W, Zhu B, Ransohoff RM, et al. Localizing central nervous system immune surveillance: menin-geal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol 2009; 65: 457-469
-
(2009)
Ann Neurol
, vol.65
, pp. 457-469
-
-
Kivisäkk, P.1
Imitola, J.2
Rasmussen, S.3
Elyaman, W.4
Zhu, B.5
Ransohoff, R.M.6
-
24
-
-
33646820687
-
Progressive multifocal leukoencephalopathy and multiple sclerosis: Lessons from natalizumab
-
Langer-Gould A, Steinman L. Progressive multifocal leukoencephalopathy and multiple sclerosis: lessons from natalizumab. Curr Neurol Neurosci Rep 2006; 6: 253-258
-
(2006)
Curr Neurol Neurosci Rep
, vol.6
, pp. 253-258
-
-
Langer-Gould, A.1
Steinman, L.2
-
26
-
-
34250159112
-
Interferon-beta: Mechanism of action and dosing issues
-
Markowitz CE. Interferon-beta: mechanism of action and dosing issues. Neurol 2007; 68: S8-11.
-
(2007)
Neurol
, vol.68
-
-
Markowitz, C.E.1
-
27
-
-
0037413467
-
A controlled trial of Natalizumab for relapsing multiple sclerosis
-
Miller DH, Khan OA, Sheremata WA, Blumhardt LD, Rice GP, Libonati MA, et al. A controlled trial of Natalizumab for relapsing multiple sclerosis. N Engl J Med 2003; 348: 15-23.
-
(2003)
N Engl J Med
, vol.348
, pp. 15-23
-
-
Miller, D.H.1
Khan, O.A.2
Sheremata, W.A.3
Blumhardt, L.D.4
Rice, G.P.5
Libonati, M.A.6
-
28
-
-
36749001706
-
Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease
-
Odoardi F, Kawakami N, Klinkert WE, Wekerle H, Flü gel A. Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proc Natl Acad Sci USA 2007a; 104: 18625-18630
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 18625-18630
-
-
Odoardi, F.1
Kawakami, N.2
Klinkert, W.E.3
Wekerle, H.4
Flügel, A.5
-
29
-
-
33846533787
-
Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalo-myelitis
-
Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, et al. Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalo-myelitis. Proc Natl Acad Sci USA 2007b; 104: 920-925
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 920-925
-
-
Odoardi, F.1
Kawakami, N.2
Li, Z.3
Cordiglieri, C.4
Streyl, K.5
Nosov, M.6
-
30
-
-
33745759762
-
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
-
Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJ, Koblan-Huberson M, et al. Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat Cell Biol 2006; 8: 771-773
-
(2006)
Nat Cell Biol
, vol.8
, pp. 771-773
-
-
Peinelt, C.1
Vig, M.2
Koomoa, D.L.3
Beck, A.4
Nadler, M.J.5
Koblan-Huberson, M.6
-
31
-
-
0023727077
-
Phenotypic and functional heterogeneity of CD4+ T cells
-
Powrie F, Mason D. Phenotypic and functional heterogeneity of CD4+ T cells. Immunol Today 1988; 9: 274-277
-
(1988)
Immunol Today
, vol.9
, pp. 274-277
-
-
Powrie, F.1
Mason, D.2
-
32
-
-
0034663895
-
+ T lymphocytes differ on CD45RC expression
-
+ T lymphocytes differ on CD45RC expression. J Immunol 2000; 165: 1816-1823
-
(2000)
J Immunol
, vol.165
, pp. 1816-1823
-
-
Ramírez, F.1
Mason, D.2
-
33
-
-
18244375249
-
Egr-2 and Egr-3 are negative regulators of T cell activation
-
Safford M, Collins S, Lutz MA, Allen A, Huang CT, Kowalski J, et al. Egr-2 and Egr-3 are negative regulators of T cell activation. Nat Immunol 2005; 6: 472-480
-
(2005)
Nat Immunol
, vol.6
, pp. 472-480
-
-
Safford, M.1
Collins, S.2
Lutz, M.A.3
Allen, A.4
Huang, C.T.5
Kowalski, J.6
-
34
-
-
34547135943
-
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes
-
Skokos D, Shakhar G, Varma R, Waite JC, Cameron TO, Lindquist RL, et al. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nat Immunol 2007; 8: 835-844
-
(2007)
Nat Immunol
, vol.8
, pp. 835-844
-
-
Skokos, D.1
Shakhar, G.2
Varma, R.3
Waite, J.C.4
Cameron, T.O.5
Lindquist, R.L.6
-
36
-
-
0020643801
-
2+ from a non-mitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
-
2+ from a non-mitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 1983; 306: 67-69
-
(1983)
Nature
, vol.306
, pp. 67-69
-
-
Streb, H.1
Irvine, R.F.2
Berridge, M.J.3
Schulz, I.4
-
38
-
-
0032193213
-
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage depleted mice
-
Tran EH, Hoekstra K, Van Rooijen N, Dijkstra CD, Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage depleted mice. J Immunol 1998; 161: 3767-3775
-
(1998)
J Immunol
, vol.161
, pp. 3767-3775
-
-
Tran, E.H.1
Hoekstra, K.2
Van Rooijen, N.3
Dijkstra, C.D.4
Owens, T.5
-
40
-
-
3142753454
-
Immunosuppressive treatment in multiple sclerosis
-
Weiner HL. Immunosuppressive treatment in multiple sclerosis. J Neurol Sci 2004; 223: 1-11.
-
(2004)
J Neurol Sci
, vol.223
, pp. 1-11
-
-
Weiner, H.L.1
-
41
-
-
0028221166
-
Animal models
-
Wekerle H, Kojima K, Lannes-Vieira J, Lassmann H, Linington C. Animal models. Ann Neurol 1994; 36: S47-53.
-
(1994)
Ann Neurol
, vol.36
-
-
Wekerle, H.1
Kojima, K.2
Lannes-Vieira, J.3
Lassmann, H.4
Linington, C.5
-
42
-
-
33748655172
-
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
-
Yeromin AV, Zhang SL, Jiang W, Yu Y, Safrina O, Cahalan MD. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 2006; 443: 226-229
-
(2006)
Nature
, vol.443
, pp. 226-229
-
-
Yeromin, A.V.1
Zhang, S.L.2
Jiang, W.3
Yu, Y.4
Safrina, O.5
Cahalan, M.D.6
|