Lyophilized Cheliensisin A submicron emulsion for intravenous injection: Characterization, in vitro and in vivo antitumor effect

International Journal of Pharmaceutics

Volumn 357, Issue 1-2, 2008, Pages 139-147

  Zhao, Dong ^a   Gong, Tao ^a   Fu, Yao ^a   Nie, Yu ^a   He, Li Li ^a   Liu, Jie ^a   Zhang, Zhi Rong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Antitumor drug; Cheliensisin A; In vivo and in vitro antitumor efficiency; Lyophilized submicron emulsion; Solubility; Stability

Indexed keywords

ANTINEOPLASTIC AGENT; CHELIENSISIN A; GC 51;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; FEMALE; FREEZE DRYING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO SELECTION; IN VIVO STUDY; LUNG METASTASIS; MALE; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURVIVAL RATE; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CHEMISTRY, PHYSICAL; COLONIC NEOPLASMS; DRUG STABILITY; ELECTROCHEMISTRY; EMULSIONS; EPOXY COMPOUNDS; FEMALE; FREEZE DRYING; HELA CELLS; HUMANS; INJECTIONS, INTRAVENOUS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; PYRONES; SOLUBILITY; SURVIVAL ANALYSIS;

EID: 42749085840     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.01.055     Document Type: Article

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