Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema

Hypertension Research

Volumn 33, Issue 7, 2010, Pages 703-707

  Ikegame, Yuka ^a   Yamashita, Kentaro ^a   Hayashi, Shin Ichiro ^a   Yoshimura, Shin Ichi ^a   Nakashima, Shigeru ^a   Iwama, Toru ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

acute cerebral ischemia; angiopoietin 1; brain edema endothelial cells; neutrophil elastase inhibitor

Indexed keywords

ANGIOPOIETIN 1; ISOLECTIN B4; LECTIN; SIVELESTAT; GLYCINE; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD VESSEL; BRAIN EDEMA; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MALE; MICROVASCULATURE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM; ACUTE DISEASE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD BRAIN BARRIER; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; DRUG EFFECTS; HYPOXIA-ISCHEMIA, BRAIN;

ACUTE DISEASE; ANGIOPOIETIN-1; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CAPILLARY PERMEABILITY; CELLS, CULTURED; GLYCINE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; LEUKOCYTE ELASTASE; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; PROTEINASE INHIBITORY PROTEINS, SECRETORY; SULFONAMIDES;

EID: 77954350424     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2010.58     Document Type: Article

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