A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats

Journal of Neurochemistry

Volumn 78, Issue 5, 2001, Pages 1064-1072

  Tonai, Takeharu ^a,e   Shiba, Kei Ichiro ^b   Taketani, Yutaka ^c   Ohmoto, Yasukazu ^d   Murata, Kaori ^d   Muraguchi, Masahiro ^d   Ohsaki, Hiroyuki ^e   Takeda, Eiji ^c   Nishisho, Takehiko ^a  

^a Dept of Obstetrics and Gynecology   (Japan)

^b SPINAL INJURIES CENTER   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^e National Hospital Organization   (Japan)

Author keywords

Cytokine induced neutrophil chemo attractant 1; Human; Interleukin 8; Rat; Spinal cord injury

Indexed keywords

CHEMOATTRACTANT; EVANS BLUE; LEUKOCYTE ELASTASE INHIBITOR; MESSENGER RNA; MYELOPEROXIDASE; SIVELESTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; LEUKOCYTE ACTIVATION; MOTOR DYSFUNCTION; NERVOUS SYSTEM INJURY; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD COMPRESSION; SPINAL CORD INJURY; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD-BRAIN BARRIER; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; GENE EXPRESSION; GLYCINE; GROWTH SUBSTANCES; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-8; LEUKOCYTE ELASTASE; MOTOR ACTIVITY; PEROXIDASE; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; SPINAL CORD; SPINAL CORD INJURIES; SULFONAMIDES;

ANIMALIA;

EID: 0034839171     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00488.x     Document Type: Article

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