Rheological characterization and in vivo evaluation of thermosensitive poloxamer-based hydrogel for intramuscular injection of piroxicam

International Journal of Pharmaceutics

Volumn 395, Issue 1-2, 2010, Pages 317-323

  Xuan, Jing Ji ^a   Balakrishnan, Prabagar ^a   Oh, Dong Hoon ^a   Yeo, Woo Hyun ^a   Park, San Man ^a   Yong, Chul Soon ^a   Choi, Han Gon ^a  

^a Yeungnam University   (South Korea)

Author keywords

Gelation time; Injectable gel; Piroxicam; Poloxamer; Syringe ability; Thermosensitive

Indexed keywords

CODANTHRAMER; PIROXICAM; POLOXAMER; SODIUM CHLORIDE; SODIUM HYDROXIDE; DELAYED RELEASE FORMULATION; DRUG CARRIER; HYDROGEL; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG SOLUBILITY; FEMALE; FLOW KINETICS; GELATION; HEAT SENSITIVITY; HYDROGEL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SUSTAINED RELEASE FORMULATION; THERMOSTABILITY; VISCOSITY; ANIMAL; AREA UNDER THE CURVE; BIOAVAILABILITY; BLOOD; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG FORMULATION; INTRAMUSCULAR DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; TEMPERATURE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG COMPOUNDING; FEMALE; HYDROGELS; INJECTIONS, INTRAMUSCULAR; PIROXICAM; POLOXAMER; RABBITS; RHEOLOGY; SODIUM CHLORIDE; SODIUM HYDROXIDE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; VISCOSITY;

EID: 77954316122     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.05.042     Document Type: Article

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