Methadone implants for methadone maintenance treatment. In vitro and in vivo animal studies

Journal of Controlled Release

Volumn 95, Issue 3, 2004, Pages 413-421

  Negrin C M ^a   Delgado, A ^a   Llabres M ^a   Evora C ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Auto induction; Biodegradable polymers; Controlled release; Deconvolution; Implants; Methadone maintenance treatment

Indexed keywords

ESTIMATION; LIVING SYSTEMS STUDIES; OPTIMIZATION; ORGANIC ACIDS; ORGANIC POLYMERS;

DECONVOLUTION; METHADONE IMPLANTS;

IMPLANTS (SURGICAL);

CHLORIDE; METHADONE; METHADONE CHLORIDE; POLYGLACTIN; POLYLACTIC ACID; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CORRELATION ANALYSIS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG FORMULATION; DRUG IMPLANT; DRUG RELEASE; DRUG SCREENING; IN VITRO STUDY; IN VIVO STUDY; MAINTENANCE THERAPY; MALE; MOUSE; MULTIPLE DRUG DOSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE;

ANIMALS; BIOCOMPATIBLE MATERIALS; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; DRUG IMPLANTS; FORECASTING; INJECTIONS, SUBCUTANEOUS; LACTIC ACID; MALE; METHADONE; MICE; OPIOID-RELATED DISORDERS; POLYGLYCOLIC ACID; POLYMERS; SPAIN; TIME FACTORS;

EID: 1542719308     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2003.12.008     Document Type: Article

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