Dose-dependent hyperlipidemia in rabbits following administration of poloxamer 407 gel

Life Sciences

Volumn 65, Issue 21, 1999, Pages PL261-PL266

  Blonder, Joan M ^a   Baird, Linda ^a   Fulfs, Jon C ^b   Rosenthal, Gary J ^a  

^a RxKinetix Inc   (United States)

^b Inhausen Research Institute Inc   (United States)

Author keywords

Drug delivery; Pluronic F 127; Poloxamer 407; Rabbits

Indexed keywords

CHOLESTEROL; POLOXAMER; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CHEMISTRY; BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; EYE DISEASE; FEMALE; GASTROINTESTINAL DISEASE; GEL; GELATINIZATION; HUMAN; HYPERLIPIDEMIA; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PROTEIN STABILITY; RABBIT; SUBCUTANEOUS DRUG ADMINISTRATION; SUSTAINED RELEASE FORMULATION; TOOTH DISEASE;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 0033569331     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0024-3205(99)00495-6     Document Type: Article

References (23)

1. I.R. Schmolka, Polymers for Controlled Drug Delivery, 189-214, CRC Press, Boca Raton, (1991).
2. J. Yao, M.L. Battell and J.H. McNeil, Can. J. Physiol. Pharmacol. 75 83-90 (1997).
3. P.L. Wang and T.P. Johnston, J. Parenter. Sci. Technol. 47 183-189 (1993).
4. I.R. Schmolka, J. Am. Oil Chem. Soc. 68 206-209 (1991).
5. K. Morikawa, F. Okada, M. Hosokawa and H. Kobayashi, Cancer Res. 47 37-41 (1987).
6. S.D. Desai and J. Blanchard, J. Pharm. Sci. 87 226-230 (1998).
7. A. Paavola, J. Yliruusi, Y. Kajimoto, E. Kalso, T. Wahlstrom and P. Rosenberg, Pharm. Res. 12 1997-2002 (1995).
8. T.P. Johnston, M.A. Punjabi and C.J. Froelich, Pharm. Res. 9 425-434 (1992).
9. S. Miyazaki, T. Tobiyama, M. Takada and D. Attwood, J. Pharm. Pharmacol. 47 455-457 (1995).
10. R. Bhardwaj and J. Blanchard, J. Pharm. Sci. 85 915-919 (1996).
11. H.J. Lee, G. Riley, O. Johnson, J.L. Cleland, N. Kim, M. Charnis, L. Bailey, E. Duenas, A. Shahzamani, M. Marian, A.J.S. Jones and S.D. Putney, J. Pharmacol. Exp. Ther. 281 1431-1439 (1997).
12. S.C. Miller and M.D. Donovan, Int. J. Pharm. 12 147-152 (1982).
13. B.-J. Lee, T.-S. Lee, B.-J. Cha, S.-H. Kim and W.-G. Kim, Int. J. Pharm. 159 105-114 (1997).
14. M. Katakam, W.R. Ravis and A.K. Banga, J. Controlled Release 49 21-26 (1997).
15. Z.G.M. Wout, E.A. Pec, J.A. Maggiore, R.H. Williams, P. Palicharla and T.P. Johnston, Journal of Parenteral Science & Technology 46 192-200 (1992).
16. W.K. Palmer, E.E. Emeson and T.P. Johnston, Atherosclerosis 136 115-123 (1998).
17. T.P. Johnston and W.K. Palmer, Biochem. Pharmacol. 46 1037-1042 (1993).
18. T.P. Johnston and W.K. Palmer, J. Cardiovasc. Pharmacol. 29 580-585 (1997).
19. J.A. Porter, B.L. Carter, T.P. Johnston and W.K. Palmer, Pharmacotherapy 15 92-98 (1995).
20. V.J. Nash, T.P. Johnston and W.K. Palmer, Pharmacotherapy 16 10-15 (1996).
21. L.P. Stratton, A. Dong, M.C. Manning and J.F. Carpenter, J. Pharm. Sci. 86 1006-1009 (1997).
22. G.L. Schaer, L.J. Spaccavento, K.F. Browne, K.A. Krueger, D. Krichbaum, J.M. Phelan, W.O. Fletcher, C.L. Grines, S. Edwards, M.K. Jolly and R.J. Gibbons, Circulation 94 298-307 (1996).
23. R.L. Hunter, C. Papadea, C.J. Gallagher, D.C. Finlayson and I.J. Check, Thromb. Haemostasis 63 6-12 (1990).