Enhanced rectal bioavailability of ibuprofen in rats by poloxamer 188 and menthol

International Journal of Pharmaceutics

Volumn 269, Issue 1, 2004, Pages 169-176

  Yong, Chul Soon ^a   Yang, Chae Ha ^b   Rhee, Jong Dal ^a   Lee, Beom Jin ^c   Kim, Dong Chool ^d   Kim, Dae Duk ^e   Kim, Chong Kook ^e   Choi, Jun Shik ^f   Choi, Han Gon ^a  

^a Yeungnam University   (South Korea)

^b Daegu Haany University   (South Korea)

^c Kangwon National University   (South Korea)

^d Chungnam National University   (South Korea)

^e Seoul National University   (South Korea)

^f Chosun University   (South Korea)

Author keywords

Ibuprofen; Menthol; Pharmacokinetics; Poloxamer 188; Solubility

Indexed keywords

IBUPROFEN; MENTHOL; POLOXAMER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DIFFUSION; DISSOLUTION; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; NONHUMAN; PRIORITY JOURNAL; RACEMIC MIXTURE; RAT; RECTUM;

EID: 0347418196     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.09.013     Document Type: Article

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