Facile synthesis of carbon-11-labeled cholesterol-based cationic lipids as new potential PET probes for imaging of gene delivery in cancer

Steroids

Volumn 75, Issue 10, 2010, Pages 715-720

  Gao, Mingzhang ^a   Wang, Min ^a   Miller, Kathy D ^a   Sledge, George W ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer imaging; Cholesterol based cationic lipids; Gene delivery; Gene therapy; Positron emission tomography; Probes

Indexed keywords

CARBON 11; CHOLESTEROL; LIPID; N METHYL N [4 (CHOLEST 5 EN 3BETA YLOXYCARBONYL)BUTYL] 4 METHYLPIPERIDINIUM IODIDE CARBON C11; N METHYL N [4 (CHOLEST 5 EN 3BETA YLOXYCARBONYL)BUTYL]MORPHOLINIUM IODIDE CARBON C11; N METHYL N [4 (CHOLEST 5 EN 3BETA YLOXYCARBONYL)BUTYL]PIPERIDINIUM IODIDE CARBON C11; N METHYL N [4 (CHOLEST 5 EN 3BETA YLOXYCARBONYL)BUTYL]PYRROLIDINIUM IODIDE CARBON C11; N METHYL N' [4 (CHOLEST 5 EN 3BETA YLOXYCARBONYL)BUTYL]IMIDAZOLIUM IODIDE CARBON C11; TRACER; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; GENE TARGETING; GENE THERAPY; ISOTOPE LABELING; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; SCINTILLATION PROBE; SOLID PHASE EXTRACTION; CHEMICAL STRUCTURE; CHEMISTRY; GENE TRANSFER; HUMAN; NEOPLASM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PROCEDURES; SYNTHESIS;

CHOLESTEROL; GENE TRANSFER TECHNIQUES; HUMANS; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY;

EID: 77954311741     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.04.009     Document Type: Article

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