Synthesis and tubulin-binding properties of new allocolchicinoids

Bioorganic Chemistry

Volumn 38, Issue 4, 2010, Pages 149-158

  Boyer, Franois Didier ^a,b   Dubois, Joëlle ^a   Thoret, Sylviane ^a   Dau, Marie Elise Tran Huu ^a   Hanna, Issam ^c  

^a CNRS   (France)

^b INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^c LABORATOIRE DE SYNTHÈSE ORGANIQUE   (France)

Author keywords

Allocolchicinoids; Diels Alder reaction; Enyne; Metathesis; Tubulin inhibitors

Indexed keywords

ALKALOID DERIVATIVE; ALLOCOLCHICINE; ALLOCOLCHICINOID B; ALLOCOLCHICINOID C; ALLOCOLCHICINOID DERIVATIVE; BIPHENYL DERIVATIVE; COLCHICINE; ESTER DERIVATIVE; METHYL GROUP; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; DIELS ALDER REACTION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; PRIORITY JOURNAL; RING CLOSING METATHESIS; STRUCTURE ACTIVITY RELATION;

ALNUS;

EID: 77954214072     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2010.03.003     Document Type: Article

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