A synthesis of (aR,7S)-(-)-N-acetylcolchinol and its conjugate with a cyclic RGD peptide

Tetrahedron

Volumn 64, Issue 21, 2008, Pages 4700-4710

  Besong, Gilbert ^a   Billen, Denis ^a   Dager, Indu ^a   Kocienski, Philip ^a   Sliwinski, Eric ^a   Tai, Lik Ren ^a   Boyle, F Thomas ^b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Asymmetric reduction; Biaryl; Colchicine; RGD peptide; Suzuki Miyaura cross coupling

Indexed keywords

BENZENE DERIVATIVE; COLCHINOL; LEWIS ACID; LITHIUM DERIVATIVE; N ACETYLCOLCHINOL ARGINYLGLYCYLASPARTIC ACID CONJUGATE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CHEMICAL REACTION; CHIRALITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; PRIORITY JOURNAL; REDUCTION; STOICHIOMETRY; STRUCTURE ANALYSIS; SUZUKI MIYAURA COUPLING;

EID: 42449137851     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.01.130     Document Type: Article

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