-
1
-
-
0345516019
-
-
(a) Perez-Ramirez, B.; Gorbunoff, M. J.; Timasheff, S. N. Biochemistry 1998, 37, 1646.
-
(1998)
Biochemistry
, vol.37
, pp. 1646
-
-
Perez-Ramirez, B.1
Gorbunoff, M.J.2
Timasheff, S.N.3
-
2
-
-
0033241269
-
-
(b) Guan, J.; Zhu, X.; Brossi, A.; Tachibana, Y.; Bastow, K. F.; Verdier-Pinard, P.; Hamel, E.; McPhail, A. T.; Lee, K. Collect. Czech. Chem. Commun. 1999, 64, 217.
-
(1999)
Collect. Czech. Chem. Commun
, vol.64
, pp. 217
-
-
Guan, J.1
Zhu, X.2
Brossi, A.3
Tachibana, Y.4
Bastow, K.F.5
Verdier-Pinard, P.6
Hamel, E.7
McPhail, A.T.8
Lee, K.9
-
3
-
-
17444428868
-
-
(c) Büttner, F.; Bergemann, S.; Guénard, D.; Gust, R.; Seitz, G.; Thoret, S. Bioorg. Med. Chem. 2005, 13, 3497.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 3497
-
-
Büttner, F.1
Bergemann, S.2
Guénard, D.3
Gust, R.4
Seitz, G.5
Thoret, S.6
-
4
-
-
33744477942
-
-
(d) Nakagawa-Goto, K.; Jung, M. K.; Hamel, E.; Wu, C.-C.; Bastow, K. F.; Brossi, A.; Ohta, S.; Lee, K.-H. Heterocycles 2005, 65, 541.
-
(2005)
Heterocycles
, vol.65
, pp. 541
-
-
Nakagawa-Goto, K.1
Jung, M.K.2
Hamel, E.3
Wu, C.-C.4
Bastow, K.F.5
Brossi, A.6
Ohta, S.7
Lee, K.-H.8
-
5
-
-
0038711432
-
-
(a) Vorogushin, A. V.; Predeus, A. V.; Wulff, W. D.; Hansen, H.-J. J. Org. Chem. 2003, 68, 5826.
-
(2003)
J. Org. Chem
, vol.68
, pp. 5826
-
-
Vorogushin, A.V.1
Predeus, A.V.2
Wulff, W.D.3
Hansen, H.-J.4
-
8
-
-
33744818526
-
-
(d) Besong, G.; Jarowicki, K.; Kocienski, P. J.; Sliwinski, E.; Boyle, F. T. Org. Biomol. Chem. 2006, 4, 2193.
-
(2006)
Org. Biomol. Chem
, vol.4
, pp. 2193
-
-
Besong, G.1
Jarowicki, K.2
Kocienski, P.J.3
Sliwinski, E.4
Boyle, F.T.5
-
9
-
-
34249297702
-
-
(e) Broady, S. D.; Golden, M. D.; Leonard, J.; Muir, J. C.; Maudet, M. Tetrahedron Lett. 2007, 48, 4627.
-
(2007)
Tetrahedron Lett
, vol.48
, pp. 4627
-
-
Broady, S.D.1
Golden, M.D.2
Leonard, J.3
Muir, J.C.4
Maudet, M.5
-
14
-
-
33748719103
-
-
(c) Diler, U.; Franz, B.; Roettele, H.; Schroeder, G.; Herges, R. J. Prakt. Chem./Chem.-Ztg. 1998, 340, 468.
-
(1998)
Prakt. Chem./Chem.-Ztg
, vol.340
, pp. 468
-
-
Diler, U.1
Franz, B.2
Roettele, H.3
Schroeder, G.4
Herges, R.J.5
-
15
-
-
37049164939
-
-
Cook, J. W.; Jack, J.; Loudon, J. D.; Buchanan, G. L.; Macmillan, J. J. Chem. Soc. 1951, 1397.
-
(1951)
J. Chem. Soc
, pp. 1397
-
-
Cook, J.W.1
Jack, J.2
Loudon, J.D.3
Buchanan, G.L.4
Macmillan, J.5
-
21
-
-
0000559897
-
-
(a) Schreiber, S. L.; Sammakia, T.; Crowe, W. E. J. Am. Chem. Soc. 1986, 108, 3128.
-
(1986)
J. Am. Chem. Soc
, vol.108
, pp. 3128
-
-
Schreiber, S.L.1
Sammakia, T.2
Crowe, W.E.3
-
23
-
-
0034725388
-
-
(c) Tanino, K.; Shimizu, T.; Miyama, M.; Kuwajima, I. J. Am. Chem. Soc. 2000, 122, 6116.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 6116
-
-
Tanino, K.1
Shimizu, T.2
Miyama, M.3
Kuwajima, I.4
-
24
-
-
0000728738
-
-
(d) Iwasawa, N.; Sakurada, F.; Iwamoto, M. Org. Lett. 2000, 2, 871.
-
(2000)
Org. Lett
, vol.2
, pp. 871
-
-
Iwasawa, N.1
Sakurada, F.2
Iwamoto, M.3
-
25
-
-
0041877411
-
-
(e) Tanino, K.; Kondo, F.; Shimizu, T.; Miyashita, M. Org. Lett. 2002, 4, 2217.
-
(2002)
Org. Lett
, vol.4
, pp. 2217
-
-
Tanino, K.1
Kondo, F.2
Shimizu, T.3
Miyashita, M.4
-
26
-
-
0037433234
-
-
(f) Tanino, K.; Onuki, K.; Asano, K.; Miyashita, M.; Nakamura, T.; Takahashi, Y.; Kuwajima, I. J. Am. Chem. Soc. 2003, 125, 1498.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 1498
-
-
Tanino, K.1
Onuki, K.2
Asano, K.3
Miyashita, M.4
Nakamura, T.5
Takahashi, Y.6
Kuwajima, I.7
-
27
-
-
0037414498
-
-
(g) Young, D. G. J.; Burlison, J. A.; Peters, U. J. Org. Chem. 2003, 68, 3494.
-
(2003)
J. Org. Chem
, vol.68
, pp. 3494
-
-
Young, D.G.J.1
Burlison, J.A.2
Peters, U.3
-
28
-
-
28044472288
-
-
(h) Iwasawa, N.; Inaba, K.; Nakayama, S.; Aoki, M. Angew. Chem., Int. Ed. 2005, 44, 7447.
-
(2005)
Angew. Chem., Int. Ed
, vol.44
, pp. 7447
-
-
Iwasawa, N.1
Inaba, K.2
Nakayama, S.3
Aoki, M.4
-
29
-
-
33847410106
-
-
(i) Olier, C.; Gastaldi, S.; Christie, S. D. R.; Bertrand, M. P. Synlett 2007, 423.
-
(2007)
Synlett
, pp. 423
-
-
Olier, C.1
Gastaldi, S.2
Christie, S.D.R.3
Bertrand, M.P.4
-
31
-
-
0043160327
-
-
For the corresponding ethers, see:, and references therein
-
(k) For the corresponding ethers, see: Baba, T.; Huang, G.; Isobe, M. Tetrahedron 2003, 59, 6851 and references therein.
-
(2003)
Tetrahedron
, vol.59
, pp. 6851
-
-
Baba, T.1
Huang, G.2
Isobe, M.3
-
32
-
-
33847393177
-
-
For recent reviews on the Nicholas reaction, see: a
-
For recent reviews on the Nicholas reaction, see: (a) Diaz, D. D.; Betancort, J. M.; Martin, V. S. Synlett 2007, 343.
-
(2007)
Synlett
, pp. 343
-
-
Diaz, D.D.1
Betancort, J.M.2
Martin, V.S.3
-
36
-
-
0033515799
-
-
In this case, the major product was 7-methoxynaphtho[2,1-b]-thiophene (50% yield), consistent with vinyl carbene insertion into the thiophene C(2)-H bond. For related chemistry, see: (a) Imamura, K.; Hirayama, D.; Yoshimura, H.; Takimiya, K.: Aso, Y.; Otsubo, T. Tetrahedron Lett. 1999, 40, 2789.
-
In this case, the major product was 7-methoxynaphtho[2,1-b]-thiophene (50% yield), consistent with vinyl carbene insertion into the thiophene C(2)-H bond. For related chemistry, see: (a) Imamura, K.; Hirayama, D.; Yoshimura, H.; Takimiya, K.: Aso, Y.; Otsubo, T. Tetrahedron Lett. 1999, 40, 2789.
-
-
-
-
38
-
-
38349168027
-
-
Acetates were chosen over alcohol leaving groups due to their superiority in benzocycloheptenyne complex syntheses; see ref 7a
-
Acetates were chosen over alcohol leaving groups due to their superiority in benzocycloheptenyne complex syntheses; see ref 7a.
-
-
-
-
39
-
-
38349146048
-
-
1H NMR spectrum, reflecting biaryl restricted rotation.
-
1H NMR spectrum, reflecting biaryl restricted rotation.
-
-
-
-
40
-
-
0037025920
-
-
Kira, K.; Tanda, H.; Hamajima, A.; Baba, T.: Takai, S.; Isobe, M. Tetrahedron 2002, 58, 6485.
-
(2002)
Tetrahedron
, vol.58
, pp. 6485
-
-
Kira, K.1
Tanda, H.2
Hamajima, A.3
Baba, T.4
Takai, S.5
Isobe, M.6
-
41
-
-
0033655836
-
-
Both 10 and 11 themselves also have significant tubulin assembly inhibitory activity. See refs 1b,c and: (a) Polański, J. Acta Biochim. Pol. 2000, 47, 37.
-
Both 10 and 11 themselves also have significant tubulin assembly inhibitory activity. See refs 1b,c and: (a) Polański, J. Acta Biochim. Pol. 2000, 47, 37.
-
-
-
-
42
-
-
0037152492
-
-
(b) Han, S.; Hamel, E.; Bastow, K. F.; McPhail, A. T.; Brossi, A.; Lee, K.-H. Bioorg. Med. Chem. Lett. 2002, 12, 2851.
-
(2002)
Bioorg. Med. Chem. Lett
, vol.12
, pp. 2851
-
-
Han, S.1
Hamel, E.2
Bastow, K.F.3
McPhail, A.T.4
Brossi, A.5
Lee, K.-H.6
|